Jeansok J Kim

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi request reprint Neural circuits and mechanisms involved in Pavlovian fear conditioning: a critical review
    Jeansok J Kim
    Department of Psychology and Program in Neurobiology and Behavior, University of Washington, Guthrie Hall, Seattle, WA 98195 1525, USA
    Neurosci Biobehav Rev 30:188-202. 2006
  2. pmc Selective enhancement of emotional, but not motor, learning in monoamine oxidase A-deficient mice
    J J Kim
    Neuroscience Program, University of Southern California, Los Angeles, CA 90089 2520, USA
    Proc Natl Acad Sci U S A 94:5929-33. 1997
  3. ncbi request reprint The stressed hippocampus, synaptic plasticity and lost memories
    Jeansok J Kim
    Department of Psychology and Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06520 8205, USA
    Nat Rev Neurosci 3:453-62. 2002
  4. ncbi request reprint Amygdala is critical for stress-induced modulation of hippocampal long-term potentiation and learning
    J J Kim
    Department of Psychology, Yale University, New Haven, Connecticut 06520 8205, USA
    J Neurosci 21:5222-8. 2001
  5. ncbi request reprint Inhibitory cerebello-olivary projections and blocking effect in classical conditioning
    J J Kim
    Neuroscience Program, University of Southern California, Los Angeles, CA 90089 2520, USA
    Science 279:570-3. 1998
  6. pmc Amygdalar stimulation produces alterations on firing properties of hippocampal place cells
    Eun Joo Kim
    Department of Psychology, University of Washington, Seattle, Washington 98195 1525, USA
    J Neurosci 32:11424-34. 2012
  7. pmc Cerebellar cortical inhibition and classical eyeblink conditioning
    Shaowen Bao
    Neuroscience Program, University of Southern California, Los Angeles, CA 90089 2520, USA
    Proc Natl Acad Sci U S A 99:1592-7. 2002
  8. ncbi request reprint Discriminative conditioning with different CS-US intervals produces temporally differentiated conditioned responses in the two eyes of the rabbit (Oryctolagus cuniculus)
    Taekwan Lee
    Department of Psychology, Yale University, USA
    Behav Neurosci 123:1085-94. 2009
  9. ncbi request reprint Stress effects in the hippocampus: synaptic plasticity and memory
    Jeansok J Kim
    Department of Psychology, University of Washington, Seattle, WA 98195 1520, USA
    Stress 9:1-11. 2006
  10. pmc Prefrontal cortex and hippocampus subserve different components of working memory in rats
    Taejib Yoon
    Department of Psychology, University of Washington, Seattle, Washington 98195 1525, USA
    Learn Mem 15:97-105. 2008

Collaborators

Detail Information

Publications32

  1. ncbi request reprint Neural circuits and mechanisms involved in Pavlovian fear conditioning: a critical review
    Jeansok J Kim
    Department of Psychology and Program in Neurobiology and Behavior, University of Washington, Guthrie Hall, Seattle, WA 98195 1525, USA
    Neurosci Biobehav Rev 30:188-202. 2006
    ..The purpose of this review is to critically evaluate the strengths and weaknesses of evidence indicating that fear conditioning depend crucially upon the amygdalar circuit and plasticity...
  2. pmc Selective enhancement of emotional, but not motor, learning in monoamine oxidase A-deficient mice
    J J Kim
    Neuroscience Program, University of Southern California, Los Angeles, CA 90089 2520, USA
    Proc Natl Acad Sci U S A 94:5929-33. 1997
    ..These results suggest that chronic elevations of monoamines, due to a deletion of the gene encoding MAOA, lead to selective alterations in emotional behavior...
  3. ncbi request reprint The stressed hippocampus, synaptic plasticity and lost memories
    Jeansok J Kim
    Department of Psychology and Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06520 8205, USA
    Nat Rev Neurosci 3:453-62. 2002
    ..Here, we provide an overview of the neurobiology of stress memory interactions, and present a neural endocrine model to explain how stress modifies hippocampal functioning...
  4. ncbi request reprint Amygdala is critical for stress-induced modulation of hippocampal long-term potentiation and learning
    J J Kim
    Department of Psychology, Yale University, New Haven, Connecticut 06520 8205, USA
    J Neurosci 21:5222-8. 2001
    ..These results indicate that an intact amygdala is necessary for the expression of the modulatory effects of stress on hippocampal LTP and memory...
  5. ncbi request reprint Inhibitory cerebello-olivary projections and blocking effect in classical conditioning
    J J Kim
    Neuroscience Program, University of Southern California, Los Angeles, CA 90089 2520, USA
    Science 279:570-3. 1998
    ..These results suggest that the inferior olive becomes functionally inhibited by the cerebellum during conditioning, and that this negative feedback process might be the neural mechanism mediating blocking...
  6. pmc Amygdalar stimulation produces alterations on firing properties of hippocampal place cells
    Eun Joo Kim
    Department of Psychology, University of Washington, Seattle, Washington 98195 1525, USA
    J Neurosci 32:11424-34. 2012
    ....
  7. pmc Cerebellar cortical inhibition and classical eyeblink conditioning
    Shaowen Bao
    Neuroscience Program, University of Southern California, Los Angeles, CA 90089 2520, USA
    Proc Natl Acad Sci U S A 99:1592-7. 2002
    ..Together, these results suggest that different aspects of the memories for eyeblink CRs are encoded in the cerebellar cortex and the cerebellar deep nuclei...
  8. ncbi request reprint Discriminative conditioning with different CS-US intervals produces temporally differentiated conditioned responses in the two eyes of the rabbit (Oryctolagus cuniculus)
    Taekwan Lee
    Department of Psychology, Yale University, USA
    Behav Neurosci 123:1085-94. 2009
    ..The results indicate that the neuronal substrates subserving CRs of the two eyes involve not only a dominant lateralization but also some avenue of bilaterality...
  9. ncbi request reprint Stress effects in the hippocampus: synaptic plasticity and memory
    Jeansok J Kim
    Department of Psychology, University of Washington, Seattle, WA 98195 1520, USA
    Stress 9:1-11. 2006
    ..This review focuses on endocrine-system-level mechanisms of stress effects in the hippocampus, and how stress, by altering the property of hippocampal plasticity, can subsequently influence hippocampal memory...
  10. pmc Prefrontal cortex and hippocampus subserve different components of working memory in rats
    Taejib Yoon
    Department of Psychology, University of Washington, Seattle, Washington 98195 1525, USA
    Learn Mem 15:97-105. 2008
    ..These results suggest that while both the mPFC and hippocampus are necessarily involved in DAT, they seem to process different informational components associated with the memory task...
  11. pmc Dorsal periaqueductal gray-amygdala pathway conveys both innate and learned fear responses in rats
    Eun Joo Kim
    Department of Psychology, University of Washington, Seattle, WA 98195 1525, USA
    Proc Natl Acad Sci U S A 110:14795-800. 2013
    ..These results suggest that the dPAG conveys unconditional stimulus information to the BLA, which directs both innate and learned fear responses, and that brain stimulation-evoked behaviors are modulated by context. ..
  12. pmc Stress-induced alterations in hippocampal plasticity, place cells, and spatial memory
    Jeansok J Kim
    Department of Psychology, University of Washington, Seattle, WA 98195 1520, USA
    Proc Natl Acad Sci U S A 104:18297-302. 2007
    ..These findings suggest that stress-induced modifications in synaptic plasticity may prevent the storage of stable "rate maps" by hippocampal place cells, which in turn may contribute to spatial memory impairments associated with stress...
  13. pmc Biologically predisposed learning and selective associations in amygdalar neurons
    Ain Chung
    Department of Psychology, University of Washington, Seattle, Washington 98195 1525, USA
    Learn Mem 18:371-4. 2011
    ..Results indicate coincident Arc mRNA activation within BLA neurons after CS-US combinations that yield rapid, efficient learning, but not after CS-US combinations that do not...
  14. ncbi request reprint Bilateral nature of the conditioned eyeblink response in the rabbit: behavioral characteristics and potential mechanisms
    Taekwan Lee
    Department of Psychology, Yale University, USA
    Behav Neurosci 122:1306-17. 2008
    ..The observed differences in the IET suggest that the effect depends largely on the specific development of eyeblink CRs rather than the CER. The neurobiological implications of this apparent bilaterality of the eyeblink CR are discussed...
  15. pmc Chronic stress selectively reduces hippocampal volume in rats: a longitudinal magnetic resonance imaging study
    Taekwan Lee
    Department of Psychology, Garland Hall, University of Wisconsin, Milwaukee, Wisconsin, USA
    Neuroreport 20:1554-8. 2009
    ..This longitudinal, within-subjects design study provides direct evidence that the hippocampus is differentially vulnerable and sensitive to chronic stress...
  16. ncbi request reprint Sex-selective effects of neonatal isolation on fear conditioning and foot shock sensitivity
    Therese A Kosten
    Yale University, New Haven, CT 06516, USA
    Behav Brain Res 157:235-44. 2005
    ..The sex-specific effect of ISO on context fear may reflect neuronal reorganization in stress responsive areas and/or sex differences in some unconditioned responses...
  17. ncbi request reprint Selective neurotoxic lesions of basolateral and central nuclei of the amygdala produce differential effects on fear conditioning
    Ja Wook Koo
    Department of Psychology, Yale University, New Haven, Connecticut 06520 8205, USA
    J Neurosci 24:7654-62. 2004
    ..Instead, the expression of conditioned fear appears to primarily involve BLA projections that course through the CeA en route to downstream fear response structures...
  18. pmc Effects of stress and hippocampal NMDA receptor antagonism on recognition memory in rats
    Kevin B Baker
    Department of Psychology, Yale University, New Haven, Connecticut 06520 8205, USA
    Learn Mem 9:58-65. 2002
    ..Together, these results suggest that stress and intrahippocampal administration of APV affect recognition memory by influencing synaptic plasticity in the hippocampus...
  19. pmc Stress impairs optimal behavior in a water foraging choice task in rats
    Lauren K Graham
    Department of Psychology, University of Washington, Seattle, Washington 98195 1525, USA
    Learn Mem 17:1-4. 2010
    ..Temporary inactivation of the amygdala during stress, however, blocked impairing effects on decision making...
  20. ncbi request reprint Differential effects of cerebellar, amygdalar, and hippocampal lesions on classical eyeblink conditioning in rats
    Taekwan Lee
    Department of Psychology, Yale University, New Haven, Connecticut 06520 8205, USA
    J Neurosci 24:3242-50. 2004
    ....
  21. ncbi request reprint A thalamo-cortico-amygdala pathway mediates auditory fear conditioning in the intact brain
    Jeffrey A Boatman
    Department of Psychology, 335 Guthrie Hall, University of Washington, Seattle, WA 98195 1525, USA
    Eur J Neurosci 24:894-900. 2006
    ..These results suggest that the thalamo-cortico-amygdala pathway is the principal auditory CS pathway when the brain is intact...
  22. ncbi request reprint Amygdalar lateralization in fear conditioning: evidence for greater involvement of the right amygdala
    Kevin B Baker
    Department of Psychology, Yale University, New Haven, CT, USA
    Behav Neurosci 118:15-23. 2004
    ..These results indicate that fear conditioning is partially disrupted with unilateral amygdalar lesions, but that the right amygdala has greater involvement than the left amygdala when conditioning occurs under a normal brain state...
  23. ncbi request reprint Early life stress impairs fear conditioning in adult male and female rats
    Therese A Kosten
    Department of Psychiatry, Yale University School of Medicine, VA CT Hospital System, 950 Campbell Ave, Building 5, 3rd Floor, West Haven, CT 06516, USA
    Brain Res 1087:142-50. 2006
    ..These opposing effects may reflect developmental differences on stress-induced alterations on hippocampal regulation of the hypothalamic-pituitary-adrenal axis...
  24. ncbi request reprint Effects of complete immunotoxin lesions of the cholinergic basal forebrain on fear conditioning and spatial learning
    Karyn M Frick
    Department of Psychology and Interdepartmental Neuroscience Program, Yale University, New Haven, Connecticut 06520, USA
    Hippocampus 14:244-54. 2004
    ..The failure of BF cholinergic lesions to impair contextual fear conditioning indicates that scopolamine-induced impairments in fear conditioning may not be mediated by affecting cholinergic input to the hippocampus and neocortex...
  25. pmc Auditory Cortex is Important in the Extinction of Two Different Tone-Based Conditioned Fear Memories in Rats
    Eun Young Song
    Department of Psychology, University of Washington Seattle, WA, USA
    Front Behav Neurosci 4:24. 2010
    ..These findings indicate that the auditory cortex contributes to extinction of wide-ranging auditory fear memories, as evidenced by deficits in both tone-on CS and tone-off CS extinction training...
  26. ncbi request reprint A computer vision-based automated Figure-8 maze for working memory test in rodents
    Samuel F Pedigo
    Department of Psychology, University of Washington, Seattle, WA 98195 1520, USA
    J Neurosci Methods 156:10-6. 2006
    ..Thus, our automated Figure-8 maze is effective at assessing working memory and provides novel behavioral measures in rodents...
  27. pmc Serotonin, stress, and conditioning
    Jeansok J Kim
    Department of Psychology and Program in Neurobiology and Behavior, University of Washington, Seattle, Washington 98195 1525, USA
    Biol Psychiatry 63:819-20. 2008
  28. ncbi request reprint Memory impairments and hippocampal modifications in adult rats with neonatal isolation stress experience
    Therese A Kosten
    Menninger Department of Psychiatry, Baylor College of Medicine and the Michael E DeBakey VA Medical Center, Research Service Line 151, 2002 Holcombe Blvd, Houston, TX 77030, USA
    Neurobiol Learn Mem 88:167-76. 2007
    ....
  29. ncbi request reprint Neonatal handling alters learning in adult male and female rats in a task-specific manner
    Therese A Kosten
    Menninger Department of Psychiatry, Baylor College of Medicine and the Michael E DeBakey VA Medical Center, Houston, TX 77030, USA
    Brain Res 1154:144-53. 2007
    ..These data suggest that neonatal handling alters learning and memory in a task-specific manner that may reflect alterations in emotional reactivity or differential effects of the manipulation on unknown neurohormonal mechanisms...
  30. ncbi request reprint Amygdalar inactivation blocks stress-induced impairments in hippocampal long-term potentiation and spatial memory
    Jeansok J Kim
    Department of Psychology and Program in Neurobiology and Behavior, University of Washington, Seattle, Washington 98195 1525, USA
    J Neurosci 25:1532-9. 2005
    ..Together, these results suggest that the amygdalar neuronal activity during stress, but not shortly after stress, is essential for the emergence of stress-induced alterations in hippocampal LTP and memory...
  31. ncbi request reprint Immediate shock deficit in fear conditioning: effects of shock manipulations
    J Landeira-Fernandez
    Departamento de Psicologia, Pontificia Universidade Catolico do Rio de Janeiro, Rio de Janeiro, Brazil
    Behav Neurosci 120:873-9. 2006
    ..However, immediate shock seems to sensitize subsequent context conditioning (Experiment 3). These findings suggest that the associative deficit produced by immediate shock is not related to the rat's ability to process the footshock US...
  32. ncbi request reprint Learning-induced enduring changes in functional connectivity among prefrontal cortical neurons
    Eun H Baeg
    Neuroscience Laboratory, Institute for Medical Sciences, Ajou University School of Medicine, Suwon 443 721, Korea
    J Neurosci 27:909-18. 2007
    ..The present finding of negatively accelerated changes in FC confirms associative learning theories and provides crucial neurophysiological evidence for Hebb's hypothesis...