Research Topics
| Kent A KiehlSummaryAffiliation: Yale University Country: USA Publications
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Detail Information
Publications
A cognitive neuroscience perspective on psychopathy: evidence for paralimbic system dysfunctionKent A Kiehl
Olin Neuropsychiatry Research Center, Institute of Living, Hartford, CT 06106, USA
Psychiatry Res 142:107-28. 2006..The paralimbic system dysfunction model of psychopathy is discussed as it relates to the extant literature on psychopathy...- An adaptive reflexive processing model of neurocognitive function: supporting evidence from a large scale (n = 100) fMRI study of an auditory oddball taskKent A Kiehl
Olin Neuropsychiatry Research Center, The Institute of Living, Hartford, CT 06106, USA
Neuroimage 25:899-915. 2005..This process may be termed 'adaptive reflexive processing.' The implications of these results for interpreting functional MRI studies are discussed... - Reproducibility of the hemodynamic response to auditory oddball stimuli: a six-week test-retest studyKent A Kiehl
Institute of Living at Hartford Hospital, Yale University School of Medicine, 200 Retreat Avenue, Fuller One Building, Hartford, CT 06106, USA
Hum Brain Mapp 18:42-52. 2003..The observed pattern of results supports the hypothesis that the hemodynamic response to target and novel stimuli is highly reproducible over the 6-week test-retest period... - Brain potentials implicate temporal lobe abnormalities in criminal psychopathsKent A Kiehl
Clinical Cognitive Neuroscience Laboratory, Olin Neuropsychiatry Research Center, Institute of Living, Hartford, CT 06106, USA
J Abnorm Psychol 115:443-53. 2006..The data are interpreted as supporting the hypothesis that psychopathy may be related to dysfunction of the paralimbic system--a system that includes parts of the temporal and frontal lobes... - Temporal lobe abnormalities in semantic processing by criminal psychopaths as revealed by functional magnetic resonance imagingKent A Kiehl
Institute of Living, 200 Retreat Ave, Harford, CT 06106, USA
Psychiatry Res 130:27-42. 2004..The results are consistent with other studies of semantic processing in psychopathy and support the theory that psychopathy is associated with right hemisphere abnormalities for processing conceptually abstract material... - Abnormal hemodynamics in schizophrenia during an auditory oddball taskKent A Kiehl
Clinical Cognitive Neuroscience Laboratory, Olin Neuropsychiatry Research Center, The Institute of Living, Hartford, Connecticut 06106, USA
Biol Psychiatry 57:1029-40. 2005..This deficit in the processing of salience stimuli might be related to abnormalities in orienting, attention, and memory processes... - Temporal lobe abnormalities in semantic processing by criminal psychopaths as revealed by functional magnetic resonance imagingKent A Kiehl
Institute of Living, Hartford, CT 06106, USA
Psychiatry Res 130:297-312. 2004..The results are consistent with other studies of semantic processing in psychopathy and support the theory that psychopathy is associated with right hemisphere abnormalities for processing conceptually abstract material... - Aberrant "default mode" functional connectivity in schizophreniaAbigail G Garrity
Trinity College, Hartford, CT, USA
Am J Psychiatry 164:450-7. 2007..It was hypothesized that the default mode network would show abnormal activation and connectivity in patients with schizophrenia... - An FMRI auditory oddball study of combined-subtype attention deficit hyperactivity disorderMichael C Stevens
Olin Neuropsychiatry Research Center, Whitehall Building, Institute of Living Hartford Hospital, Hartford, CT 06106, USA
Am J Psychiatry 164:1737-49. 2007..However, the relationship between abnormal neurocognition and dysfunction in specific brain regions in ADHD remains unclear... - Brain network dynamics during error commissionMichael C Stevens
Olin Neuropsychiatry Research Center, The Institute of Living Hartford Hospital, Hartford, Connecticut 06106, USA
Hum Brain Mapp 30:24-37. 2009..These findings characterize the spatial structure of neural networks underlying error commission and identify neurobiological differences between adolescents and adults... - Functional neural networks underlying response inhibition in adolescents and adultsMichael C Stevens
Olin Neuropsychiatry Research Center, Hartford, CT 06106, United
Behav Brain Res 181:12-22. 2007..We identify and characterize several age-related differences in the function of neural circuits that are associated with behavioral performance changes across adolescent development... - An fMRI study of working memory in first-degree unaffected relatives of schizophrenia patientsShashwath A Meda
Olin Neuropsychiatry Research Center, Institute of Living at Hartford Hospital, 200 Retreat Avenue, Hartford, CT 06106, USA
Schizophr Res 104:85-95. 2008..Additionally, fMRI differences in both conditions were modulated by load, with a parametric increase in between-group differences with load in several key regions during encoding and an opposite effect during response selection... - Functional neural circuits for mental timekeepingMichael C Stevens
Olin Neuropsychiatry Research Center, Hartford, Connecticut 06106, USA
Hum Brain Mapp 28:394-408. 2007..These findings are discussed within the context of current biological and information processing models of neural timekeeping... - A functional magnetic resonance imaging study of working memory abnormalities in schizophreniaMatthew R Johnson
Olin Neuropsychiatry Research Center, The Institute of Living at Hartford Hospital, Hartford, CT, USA
Biol Psychiatry 60:11-21. 2006..Additionally, differences between encoding and retrieval suggest that WM dysfunction may be manifested differently during the distinct phases of encoding, maintenance, and retrieval... - The hemodynamics of oddball processing during single-tone and two-tone target detection tasksMichael C Stevens
Clinical Cognitive Neuroscience Laboratory, Olin Neuropsychiatry Research Center, Whitehall Building, The Institute of Living/Hartford Hospital, CT 06106, USA
Int J Psychophysiol 60:292-303. 2006..The results are discussed as they relate to the understanding of neurocognitive function pertaining to contextual manipulations in general, and orienting processes in particular... - Modulation of temporally coherent brain networks estimated using ICA at rest and during cognitive tasksVince D Calhoun
Olin Neuropsychiatry Research Center, Institute of Living, Hartford, Connecticut 06106, USA
Hum Brain Mapp 29:828-38. 2008..In summary, TCNs show considerable promise as potential imaging biological markers of brain diseases, though each network needs to be studied in more detail... - Aberrant localization of synchronous hemodynamic activity in auditory cortex reliably characterizes schizophreniaVince D Calhoun
Institute of Living, Olin Neuropsychiatry Research Center, 200 Retreat Avenue, Hartford, CT 06106, USA
Biol Psychiatry 55:842-9. 2004.... - Temporal lobe and "default" hemodynamic brain modes discriminate between schizophrenia and bipolar disorderVince D Calhoun
Olin Neuropsychiatry Research Center, Institute of Living, Hartford, Connecticut, USA
Hum Brain Mapp 29:1265-75. 2008..A combination of two such hemodynamic brain networks shows promise as a biomarker for schizophrenia and bipolar disorder... - A method for multitask fMRI data fusion applied to schizophreniaVince D Calhoun
Olin Neuropsychiatry Research Center, Institute of Living, Hartford, Connecticut 06106, USA
Hum Brain Mapp 27:598-610. 2006..It thus provides a way to integrate and probe brain networks using a variety of tasks and may increase our understanding of coordinated brain networks and the impact of pathology upon them... - Hemispheric differences in hemodynamics elicited by auditory oddball stimuliMichael C Stevens
Olin Neuropsychiatry Research Center, The Institute of Living, Hartford, CT 06106, USA; Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, USA
Neuroimage 26:782-92. 2005..The results (1) support the proposal that the right hemisphere is differentially engaged in processing salient stimuli and (2) demonstrate the successful use of a new voxel-based laterality analysis technique for fMRI data... - Interparticipant correlations: a model free FMRI analysis techniqueMartin P Hejnar
Olin Neuropsychiatry Research Center, Institute of Living, Hartford, Connecticut 06106, USA
Hum Brain Mapp 28:860-7. 2007..This technique, designed to have increased sensitivity to inter-subject correlations that are not necessarily task-related, may potentially be useful as a compliment to model-based approaches... - fMRI in an oddball task: effects of target-to-target intervalMichael C Stevens
Olin Neuropsychiatry Research Center, The Institute of Living, Hartford, Connecticut 06106, USA
Psychophysiology 42:636-42. 2005..There was no such effect of novel interval, suggesting that neuronal modulation may only occur for task-relevant stimuli, possibly in the service of strategic resource allocation processes... - Dysfunctional action monitoring hyperactivates frontal-striatal circuits in obsessive-compulsive disorder: an event-related fMRI studyNicholas Maltby
Anxiety Disorders Center, The Institute of Living Hartford Hospital, Hartford, CT 06106, USA
Neuroimage 24:495-503. 2005..These results suggest that correctly rejected, high-conflict trials that require response inhibition may provide a better model than error trials of compulsive behaviors in OCD... - Sex-related differences in amygdala activity influences immediate memoryDeane E Aikins
Department of Psychiatry, Yale University, USA
Neuroreport 21:273-6. 2010..Our results indicate that increased amygdala activation while viewing unpleasant pictures may preferentially facilitate immediate recognition memory in men relative to women... - Attentional modulation of the amygdala varies with personalitySteven B Most
Department of Psychology, Yale University, New Haven, CT 06520, USA
Neuroimage 31:934-44. 2006.... - Reading anomalous sentences: an event-related fMRI study of semantic processingKent A Kiehl
Institute of Living at Hartford Hospital, Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
Neuroimage 17:842-50. 2002..The results are discussed as they relate to the localization of the cerebral sites underlying semantic processing in general and the localization of the scalp recorded N400 event-related potential in particular... - Abnormal function of the brain system supporting motivated attention in medicated patients with schizophrenia: an fMRI studyPeter F Liddle
Department of Psychiatry, University of British Columbia, Vancouver BC, Canada
Psychol Med 36:1097-108. 2006..Patients with schizophrenia have an impaired ability to generate activity that is appropriate to current circumstances and goals... - Rostral anterior cingulate cortex dysfunction during error processing in schizophreniaKristin R Laurens
Department of Psychiatry, University of British Columbia, Vancouver, Canada
Brain 126:610-22. 2003.... - Infection, incest, and iniquity: investigating the neural correlates of disgust and moralityJana Schaich Borg
Stanford University, USA
J Cogn Neurosci 20:1529-46. 2008.... - Error-related negativity and correct response negativity in schizophreniaAlan T Bates
Department of Psychiatry, University of British Columbia, BC, Vancouver, Canada
Clin Neurophysiol 113:1454-63. 2002..Patients with high disorganization symptoms may employ an abnormal strategy for comparing actual response outcome with desired response outcome, while patients with psychomotor poverty may be less emotionally responsive to errors... - A supramodal limbic-paralimbic-neocortical network supports goal-directed stimulus processingKristin R Laurens
Department of Forensic Mental Health Science, Institute of Psychiatry, King's College London, University of London, London, United Kingdom
Hum Brain Mapp 24:35-49. 2005..Paralimbic cortex offers an important site for the convergence of motivational/goal-directed influences from limbic cortex with stimulus processing and response selection mediated within the frontoparietal areas... - Attention orienting dysfunction during salient novel stimulus processing in schizophreniaKristin R Laurens
Department of Forensic Mental Health Science, Institute of Psychiatry, King s College London, University of London, Box P023, De Crespigny Park, London SE5 8AF, UK
Schizophr Res 75:159-71. 2005..In addition, trend results suggest that patients experienced increased distraction by novel stimuli... - Emotional Intelligence predicts individual differences in social exchange reasoningDeidre L Reis
Department of Psychology, Yale University, Box 208205, New Haven, CT 06520, USA
Neuroimage 35:1385-91. 2007..The results are the first to directly suggest that EI is mediated in part by mechanisms supporting social reasoning and validate a new approach to investigating EI in terms of more basic information processing mechanisms... - State dependent changes in error monitoring in schizophreniaAlan T Bates
Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada
J Psychiatr Res 38:347-56. 2004....