Research Topics
| W N KernanSummaryAffiliation: Yale University Country: USA Publications
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Detail Information
Publications
Blood pressure exceeding national guidelines among women after strokeW N Kernan
Departments of Internal Medicine, Yale University School of Medicine, New Haven, CT 06504, USA
Stroke 31:415-9. 2000..The purpose of this study was to determine how commonly blood pressure exceeds national guidelines among patients who have had one of these events...
Boosting enrollment in neurology trials with Local Identification and Outreach Networks (LIONs)W N Kernan
Departments of Internal Medicine, Yale School of Medicine, New Haven, CT 06519, USA
Neurology 72:1345-51. 2009..Our purpose was to develop a geographically localized, multi-institution strategy for improving enrolment in a trial of secondary stroke prevention...
Disagreement between students and preceptors regarding the value of teaching behaviors for ambulatory care settingsWalter N Kernan
Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06519, USA
Teach Learn Med 20:143-50. 2008..Medical students and preceptors commonly disagree on methods of clinical instruction in ambulatory care, although the extent of the problem is not documented...
Stroke after transient ischaemic attack: dealing in futuresWalter N Kernan
Yale University School of Medicine, New Haven, CT 06519, USA
Lancet 369:251-2. 2007
Student faculty rounds: a peer-mediated learning activity for internal medicine clerkshipsWalter N Kernan
Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520 8025, USA
Med Teach 27:140-4. 2005..Adequate faculty guidance is needed to assure students design conferences for maximum educational effectiveness...
Decline in physical performance among women with a recent transient ischemic attack or ischemic stroke: opportunities for functional preservation a report of the Women's Estrogen Stroke TrialWalter N Kernan
Department of Medicine, Yale University School of Medicine, P O Box 208025, New Haven, CT 06520 8025, USA
Stroke 36:630-4. 2005..To examine this possibility, we measured change in physical performance, independent of subsequent stroke, among women with a recent ischemic stroke or transient ischemic attack (TIA)...
Prevalence of abnormal glucose tolerance following a transient ischemic attack or ischemic strokeWalter N Kernan
Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06520 8025, USA
Arch Intern Med 165:227-33. 2005..We conducted this study to determine if IGT and DGT are sufficiently common among patients with TIA and ischemic stroke to warrant therapeutic trials of antihyperglycemic agents...
Assessing the teaching behaviors of ambulatory care preceptorsWalter N Kernan
Yale University School of Medicine, P O Box 208025, New Haven, CT 06520 8025, USA
Acad Med 79:1088-94. 2004..The purpose of this research was to (1) develop an instrument for measuring teaching behavior of ambulatory care preceptors (the Teaching Encounter Card), and (2) assess current teaching practices at one institution...
Boosting enrolment in clinical trials: validation of a regional network modelW Kernan
IRIS Coordinating Center, Suite 515, 2 Church Street South, New Haven, CT 06519, USA
Clin Trials 8:645-53. 2011..Clinical trials of stroke therapy have been hampered by slow rates of enrolment...
The stroke prognosis instrument II (SPI-II) : A clinical prediction instrument for patients with transient ischemia and nondisabling ischemic strokeW N Kernan
Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520 8025, USA
Stroke 31:456-62. 2000..In this article we validate and improve SPI-I (creating SPI-II)...
Impaired insulin sensitivity among nondiabetic patients with a recent TIA or ischemic strokeW N Kernan
Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520 8025, USA
Neurology 60:1447-51. 2003..To determine the prevalence of impaired insulin sensitivity among nondiabetic patients with a recent TIA or nondisabling ischemic stroke...
Pioglitazone improves insulin sensitivity among nondiabetic patients with a recent transient ischemic attack or ischemic strokeWalter N Kernan
Department of Medicine, Yale University School of Medicine, PO Box 208025, New Haven, CT 06520 8025, USA
Stroke 34:1431-6. 2003....
Insulin resistance and risk for strokeW N Kernan
Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA
Neurology 59:809-15. 2002..Insulin resistance is also common among nondiabetic individuals, and may be an important risk factor for stroke in both populations. The authors review the definition, epidemiology, and treatment of insulin resistance...
A clinical trial of estrogen-replacement therapy after ischemic strokeC M Viscoli
Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn. 06520-8056, USA
N Engl J Med 345:1243-9. 2001..CONCLUSIONS: Estradiol does not reduce mortality orthe recurrence of stroke in postmenopausal women with cerebrovascular disease. This therapy should not be prescribed for the secondary prevention of cerebrovascular disease...
A quality-of-life instrument for young hemorrhagic stroke patientsA G Hamedani
Yale University School of Medicine, New Haven, CT, USA
Stroke 32:687-95. 2001..CONCLUSIONS: HSQuale is a reliable and valid QOL instrument. Compared with other outcome measures, it assesses a broader range of deficits and is better able to discriminate among subgroups of hemorrhagic stroke survivors...
Major risk factors for intracerebral hemorrhage in the young are modifiableEdward Feldmann
Department of Clinical Neurosciences, Brown Medical School, 110 Lockwood St, Providence, RI 02903, USA
Stroke 36:1881-5. 2005..To identify risk factors for intracerebral hemorrhage (ICH), we examined data from the Hemorrhagic Stroke Project (HSP), a case-control study of hemorrhagic stroke among men and women aged 18 to 49 years...
Altruism as a reason for participation in clinical trials was independently associated with adherenceJulie R Rosenbaum
Yale Primary Care Internal Medicine Residency, Waterbury Hospital Health Center, Department of Medicine, CT 06721, USA
J Clin Epidemiol 58:1109-14. 2005..To determine whether altruism as reason for participation in research is independently associated with adherence to a medical regimen in a clinical trial...
Obstructive sleep apnea as a risk factor for stroke and deathH Klar Yaggi
Section of Pulmonary and Critical Care Medicine, Yale Center for Sleep Medicine, Yale University School of Medicine, New Haven, Conn 06520, USA
N Engl J Med 353:2034-41. 2005..005). CONCLUSIONS: The obstructive sleep apnea syndrome significantly increases the risk of stroke or death from any cause, and the increase is independent of other risk factors, including hypertension...
Factors associated with medical students' career choices regarding internal medicineKaren E Hauer
Department of Medicine, University of California, San Francisco, 533 Parnassus Ave, U137, Box 0131, San Francisco, CA 94143 0131, USA
JAMA 300:1154-64. 2008..The factors influencing current students' career choices regarding IM are unclear...
Clinical assessment of function among women with a recent cerebrovascular event: a self-reported versus performance-based measurePamela L Owens
Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
Ann Intern Med 136:802-11. 2002..Self-reported functional status is a commonly used health measure in clinical settings, yet the optimal approach for assessing function is often debated...
Racial disparities in stroke risk factors: the impact of socioeconomic statusDawn M Bravata
Clinical Epidemiology Research Center, Veterans Affairs Connecticut Healthcare System, West Haven, CT 06516, USA
Stroke 36:1507-11. 2005..Our objective was to determine if differences in income, education, and insurance, as well as differences in the prevalence of stroke risk factors, accounted for the association between ethnicity and stroke...
Influence of race, clinical, and other socio-demographic features on trial participationGiselle Corbie-Smith
Department of Social Medicine, Division of General Medicine and Clinical Epidemiology, University of North Carolina at Chapel Hill, Wing D, Medical School, CB 7240, Chapel Hill, NC 27599, USA
J Clin Epidemiol 56:304-9. 2003..94-0.97), hysterectomy (OR 1.78, 95% CI 1.27-2.50), no cognitive impairment (OR 1.70, 95% CI 1.10-2.63), history of volunteerism (OR 1.62, 95% CI 1.02-2.63), and previous estrogen use (RR 1.58, 95% CI 1.08-2.30)...
Integrating teaching skills and clinical content in a faculty development workshopMichael L Green
Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA
J Gen Intern Med 18:468-74. 2003..Integrating clinical content with clinical teaching in a faculty development workshop is feasible, can improve clinical and teaching skills, and can facilitate behavior change...
Major risk factors for aneurysmal subarachnoid hemorrhage in the young are modifiableJoseph P Broderick
Department of Neurology, University of Cincinnati, College of Medicine, Cincinnati, Ohio 45267, USA
Stroke 34:1375-81. 2003..To identify risk factors for subarachnoid hemorrhage (SAH) and intracerebral hemorrhage, we designed a case-control study of men and women 18 to 49 years of age (the Hemorrhagic Stroke Project [HSP]). This report focuses on SAH...
Two measures of insulin sensitivity provided similar information in a U.S. populationDawn M Bravata
Clinical Epidemiology Unit, Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA
J Clin Epidemiol 57:1214-7. 2004..This project describes the range of observed values of the HOMA and FPI in a large sample of the U.S. population...
Estrogen therapy and risk of cognitive decline: results from the Women's Estrogen for Stroke Trial (WEST)Catherine M Viscoli
Yale University School of Medicine, Department of Internal Medicine, 333 Cedar St, Room IE 61 SHM, PO Box 208025, New Haven, CT 06520 8025, USA
Am J Obstet Gynecol 192:387-93. 2005..This study was undertaken to assess whether estrogen therapy (ET) reduces the risk of cognitive decline in women with cerebrovascular disease...
Association between impaired insulin sensitivity and strokeDawn M Bravata
Clinical Epidemiology Research Center CERC, VA Connecticut Healthcare System, 950 Campbell Avenue, West Haven, CT 06516, USA
Neuroepidemiology 25:69-74. 2005..Prior research has indicated an association between insulin resistance and stroke; we sought to determine if this association persists after adjusting for stroke risk factors, including glycemic control...
The Clerkship Directors in Internal Medicine's agenda for advancing medical student education in internal medicineWalter N Kernan
Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA
Am J Med 117:713-7. 2004
Re: Evaluation of acute candesartan cilexetil therapy in stroke survivorsWalter N Kernan
Stroke 34:e237-8; author reply e237-8. 2003
Rapid intervention for TIA: a new standard emergesWalter N Kernan
Lancet Neurol 6:940-1. 2007
Research Grants
- Insulin Resistance Intervention after Stroke TrialWalter Kernan; Fiscal Year: 2007..If effective, pioglitazone will be comparable to carotid endarterectomy for symptomatic disease or anticoacjulation for atrial fibrillation in terms of vascular events prevented...
