Research Topics
| S D KatzSummaryAffiliation: Yale University Country: USA Publications
Research Grants
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Detail Information
Publications
Peripheral limitations of maximal aerobic capacity in patients with chronic heart failureStuart D Katz
Yale University School of Medicine, Section of Cardiovascular Medicine, Heart Failure Center, New Haven, Conn 06510, USA
J Nucl Cardiol 9:215-25. 2002
Vascular endothelial dysfunction and mortality risk in patients with chronic heart failureStuart D Katz
Department of Internal Medicine, Yale University School of Medicine, 135 College St, Ste 301, New Haven, CT 06510, USA
Circulation 111:310-4. 2005..Endothelial function is known to be impaired in subjects with chronic heart failure (CHF), but the association between endothelial function and subsequent mortality risk in CHF has not been previously reported...
Mechanisms and treatment of anemia in chronic heart failureStuart D Katz
Yale University School of Medicine, 135 College Street, Suite 301, New Haven, CT 06510, USA
Congest Heart Fail 10:243-7. 2004..Additional studies are needed to determine the safety and efficacy of long-term erythropoietic therapy in chronic HF patients...
Efficacy and safety of sildenafil citrate in men with erectile dysfunction and chronic heart failureStuart D Katz
Department of Internal Cardiovascular Medicine, Yale University School of Medicine, New Haven, Connecticut 06510, USA
Am J Cardiol 95:36-42. 2005..The incidence of events related to cardiovascular effects was low. Sildenafil is an effective and well-tolerated management of ED in men who have mild to moderate CHF...
Potential role of type 5 phosphodiesterase inhibition in the treatment of congestive heart failureS D Katz
Yale University School of Medicine, Heart Failure Center, Yale University, 135 College Street, Suite 201, New Haven, CT 06510, USA
Congest Heart Fail 9:9-15. 2003..Further studies are warranted to characterize the safety and efficacy of type 5 phosphodiesterase inhibition in the treatment of chronic heart failure...
Blood volume assessment in the diagnosis and treatment of chronic heart failureStuart D Katz
Department of Internal Medicine, Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, Connecticut 06510, USA
Am J Med Sci 334:47-52. 2007..Additional work is needed to determine the clinical utility of serial blood volume measurements in the management of patients with CHF...
Potential role of statins in the treatment of heart failureStuart D Katz
Yale Heart Failure and Transplant Center, Yale University School of Medicine, New Haven, CT, USA
Curr Atheroscler Rep 10:318-23. 2008..Until further information becomes available, routine use of statins is not recommended in the heart failure population...
Comparison of metabolic vasodilation in response to exercise and ischemia and endothelium-dependent flow-mediated dilation in African-American versus non-African-American patients with chronic heart failureAna Silvia Androne
Department of Internal Medicine, Yale University College of Medicine, New Haven, Connecticut, USA
Am J Cardiol 97:685-9. 2006..Impaired vasodilation may contribute to differences in therapeutic response and clinical outcomes in African-American patients with chronic HF...
Iron sucrose augments homocysteine-induced endothelial dysfunction in normal subjectsH Zheng
Department of Medicine, Yale University School of Medicine, New Haven, Conneticut 06510, USA
Kidney Int 69:679-84. 2006..This potential mechanistic link between intravenous iron and endothelial dysfunction warrants further study of cardiovascular effects of intravenous iron in anemic chronic kidney disease populations...
Inhibition of angiotensin-converting enzyme and phosphodiesterase type 5 improves endothelial function in heart failureKatarzyna Hryniewicz
Department of Internal Medicine, Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, CT 06510, U.S.A
Clin Sci (Lond) 108:331-8. 2005..Therefore further work to characterize chronic effects of combined ACE and PDE5 inhibition on endothelial function are warranted...
Iron stores and vascular function in voluntary blood donorsHaoyi Zheng
Department of Internal Medicine, Yale University School of Medicine, 135 College St, Suite 301, New Haven, CT 06510, USA
Arterioscler Thromb Vasc Biol 25:1577-83. 2005..These findings support a potential link between blood donation and reduced cardiovascular risk that warrants further investigation in prospective outcome studies...
Phosphodiesterase 5 inhibition in chronic heart failure and pulmonary hypertensionMilan D Patel
Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, Connecticut 06510, USA
Am J Cardiol 96:47M-51M. 2005..Additional studies are needed to determine the therapeutic potential of this class of agents in these disease states...
Acetylcholinesterase inhibition with pyridostigmine improves heart rate recovery after maximal exercise in patients with chronic heart failureA S Androne
Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA
Heart 89:854-8. 2003..A specific effect of pyridostigmine on heart rate one minute after exercise suggests that pyridostigmine augments parasympathetic tone in patients with CHF...
Relation of unrecognized hypervolemia in chronic heart failure to clinical status, hemodynamics, and patient outcomesAna Silvia Androne
Department of Internal Medicine, Yale University School of Medicine, 135 College Street, New Haven, CT 06510, USA
Am J Cardiol 93:1254-9. 2004..13 to 6.19, p = 0.025). These findings demonstrate that clinically unrecognized hypervolemia is frequently present in nonedematous patients with CHF and is associated with increased cardiac filling pressures and worse patient outcomes...
Partial reversal of cachexia by beta-adrenergic receptor blocker therapy in patients with chronic heart failureKatarzyna Hryniewicz
Department of Internal Medicine, Yale University College of Medicine, New Haven, Connecticut 06510, USA
J Card Fail 9:464-8. 2003..Further work is needed to determine the role the sympathetic nervous system in the pathogenesis of cachexia in patients with CHF...
Treatment of anemia in patients with chronic heart failureStuart D Katz
Department of Internal Medicine, Yale University College of Medicine, New Haven, CT 06510, USA
J Card Fail 10:S13-6. 2004..Additional studies are needed to determine the safety and efficacy of long-term erythropoietic therapy in CHF patients...
The prevalence of anemia in chronic heart failure and its impact on the clinical outcomesYi da Tang
Department of Internal Medicine, Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, CT 06510, USA
Heart Fail Rev 13:387-92. 2008..These data provide the rationale for interventional treatment trials to determine if anemia is in the causal pathway for disease progression and increased mortality risk in HF patients...
Effects of recombinant human erythropoietin on antiplatelet action of aspirin and clopidogrel in healthy subjects: results of a double-blind, placebo-controlled randomized trialYi da Tang
Department of Internal Medicine, Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, CT 06510, USA
Am Heart J 154:494.e1-7. 2007..Whether prothrombotic effects of rHuEpo mitigate the effects of antiplatelet agents used in acute coronary syndrome patients is unknown...
Anemia in chronic heart failure: prevalence, etiology, clinical correlates, and treatment optionsYi-Da Tang
Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06510, USA
Circulation 113:2454-61. 2006
Insulin sensitivity, vascular function, and iron stores in voluntary blood donorsHaoyi Zheng
Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, 135 College St, New Haven, CT 06510, USA
Diabetes Care 30:2685-9. 2007..We sought to determine whether iron-dependent changes in glucose metabolism may contribute to improved vascular function in blood donors...
Comparative costs of home positive inotropic infusion versus in-hospital care in patients awaiting cardiac transplantationShrikanth P Y Upadya
Yale University School of Medicine, Department of Internal Medicine, Section of Cardiovascular Medicine, New Haven, Connecticut 06510, USA
J Card Fail 10:384-9. 2004..CONCLUSION: Outpatient inotropic therapy combined with AICD implantation in selected patients awaiting cardiac transplantation is an effective cost-minimizing strategy...
Home continuous positive inotropic infusion as a bridge to cardiac transplantation in patients with end-stage heart failureShrikanth Upadya
Yale University School of Medicine, Department of Internal Medicine, New Haven, Connecticut 06510, USA
J Heart Lung Transplant 23:466-72. 2004..CONCLUSIONS: Continuous positive inotropic therapy at home was safe and was associated with decreased health care costs in selected patients awaiting cardiac transplantation...
Comparison of suppression of the circulating and vascular renin-angiotensin system by enalapril versus trandolapril in chronic heart failureUlrich P Jorde
Division of Cardiology, New York University School of Medicine, New York, New York, USA
Am J Cardiol 94:1501-5. 2004....
Effect of dexrazoxane on homocysteine-induced endothelial dysfunction in normal subjectsHaoyi Zheng
Department of Medicine, Peking Union Medical College Hospital, Beijing, China
Arterioscler Thromb Vasc Biol 22:E15-8. 2002..CONCLUSIONS: Administration of the novel antioxidant agent dexrazoxane prevents homocysteine-induced impairment of vascular endothelial function in the brachial artery of healthy subjects...
Elevated plasma aldosterone levels despite complete inhibition of the vascular angiotensin-converting enzyme in chronic heart failureUlrich P Jorde
Division of Circulatory Physiology, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA
Circulation 106:1055-7. 2002..Complete inhibition of the vascular converting enzyme does not obviate the need for aldosterone receptor blockade in patients with CHF...
Hemodilution is common in patients with advanced heart failureAna-Silvia Androne
Department of Medicine, Columbia University, New York, NY, USA
Circulation 107:226-9. 2003..Patients with hemodilution tend to do worse than patients with true anemia, which suggests that volume overload may be an important mechanism contributing to the poor outcome in anemic CHF patients...
Effect of erythropoietin on exercise capacity in patients with moderate to severe chronic heart failureDonna M Mancini
Department of Medicine, Columbia Presbyterian Medical Center, New York, NY, USA
Circulation 107:294-9. 2003..An increase in hemoglobin could enhance exercise performance by increasing oxygen delivery. We investigated the effect of erythropoietin (EPO) on exercise performance in anemic patients with CHF...
Association of extended work shifts, vascular function, and inflammatory markers in internal medicine residents: a randomized crossover trialHaoyi Zheng
JAMA 296:1049-50. 2006
Dissociation between exercise hemodynamics and exercise capacity in patients with chronic heart failure and marked increase in ejection fraction after treatment with beta-adrenergic receptor antagonistsMathew Maurer
Division of Circulatory Physiology, Columbia Presbyterian Medical Center, New York, New York, USA
Am J Cardiol 91:356-60. 2003
Comparative effects of carvedilol and metoprolol on regional vascular responses to adrenergic stimuli in normal subjects and patients with chronic heart failureKatarzyna Hryniewicz
Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA
Circulation 108:971-6. 2003..These data suggest that long-term benefits of carvedilol in heart failure are not mediated by alpha-adrenergic blockade...
Vasopressor response to angiotensin II infusion in patients with chronic heart failure receiving beta-blockersTimothy J Vittorio
Division of Circulatory Physiology, Columbia Presbyterian Medical Center, New York, NY 10032, USA
Circulation 107:290-3. 2003..Whether this is due to the alpha1-adrenergic blocking or other ancillary properties of carvedilol warrants further investigation...
Hospitalization for heart failure in the presence of a normal left ventricular ejection fraction: results of the New York Heart Failure RegistryMarc Klapholz
Saint Vincent Catholic Medical Centers, New York, New York, USA
J Am Coll Cardiol 43:1432-8. 2004..2%. CONCLUSIONS: Patients hospitalized for HFNEF are most often chronically incapacitated elderly women with a history of hypertension and increased LV mass. Reasons for clinical decompensation are identified in only one-half of patients...
Comparison of blood volume characteristics in anemic patients with low versus preserved left ventricular ejection fractionsDmitry Abramov
Columbia University Medical Center, New York, New York, USA
Am J Cardiol 102:1069-72. 2008....
Research Grants
- Studies on Genetics in Heart FailureStuart Katz; Fiscal Year: 2007..The proposed studies will advance applicant career development and provide new insight into pathophysiology of CHF. ..
