Research Topics
Species | Arie KaffmanSummaryAffiliation: Yale University Country: USA Publications
Research Grants
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Detail Information
Publications
Neurodevelopmental sequelae of postnatal maternal care in rodents: clinical and research implications of molecular insightsArie Kaffman
Abraham Ribicoff Labs, Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06598, USA
J Child Psychol Psychiatry 48:224-44. 2007..Finally, the relevance of findings reported in rodents to those noted in non-human primates and humans are assessed and the research and clinical implications of these observations for future work are explored...
New frontiers in animal research of psychiatric illnessArie Kaffman
Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
Methods Mol Biol 829:3-30. 2012..A better understanding of this issue, in animals, is the key for defining human psychopathology, and the development of earlier and more effective interventions for mental illness...- Early life stress inhibits expression of a novel innate immune pathway in the developing hippocampusLan Wei
Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
Neuropsychopharmacology 37:567-80. 2012.... - Early life stress increases anxiety-like behavior in Balbc mice despite a compensatory increase in levels of postnatal maternal careLan Wei
Abraham Ribicoff Labs, Department of Psychiatry, Yale University School of Medicine, 34 Park Street, CMHC, rm S310, New Haven CT 06517, USA
Horm Behav 57:396-404. 2010..We propose that exposure to stress during the postnatal period overrides the ability of high levels of postnatal maternal care to program anxiety-like behavior by inhibiting the normal growth spurt that characterizes this period... - Affiliative behavior requires juvenile, but not adult neurogenesisLan Wei
Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06511, USA
J Neurosci 31:14335-45. 2011..Additional work is needed to determine whether ablation of juvenile neurogenesis in the subgranular zone and/or the subventricular zone is responsible for the social abnormalities seen after global elimination of juvenile neurogenesis... - Early-life stress, corticotropin-releasing factor, and serotonin transporter gene: a pilot studyJeremy D Coplan
State University of New York SUNY, Downstate Medical Center, Department of Psychiatry, Brooklyn, NY 11203, USA
Psychoneuroendocrinology 36:289-93. 2011..CSF CRF concentrations were elevated specifically in the VFD "s/s" and "s/l" allele group in comparison to each of the remaining three groups, indicating a gene-by-environment (G×E) interaction...
Research Grants
- Effect of maternal care on neurogenesis and behaviorArie Kaffman; Fiscal Year: 2007..We believe that such close collaboration between clinicians and basic behavioral-neuroscience provides the kind of translational work that will yield new treatment strategies for affective disorders in the future. ..