Joshua Johnson

Summary

Affiliation: Yale University
Country: USA

Publications

  1. pmc mTOR controls ovarian follicle growth by regulating granulosa cell proliferation
    James Yu
    Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, New Haven, Connecticut, United States of America
    PLoS ONE 6:e21415. 2011
  2. doi request reprint Ovarian aging: breaking up is hard to fix
    Joshua Johnson
    Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06510, USA
    Sci Transl Med 5:172fs5. 2013
  3. doi request reprint Ovarian cryopreservation strategies and the fine control of ovarian follicle development in vitro
    Joshua Johnson
    Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, New Haven, Connecticut, USA
    Ann N Y Acad Sci 1221:40-6. 2011
  4. doi request reprint Oocyte destruction is activated during viral infection
    Travis C Thomson
    Department of Obstetrics, Gynecology, and Reproductive Sciences Division of Reproductive Endocrinology and Infertility, Yale School of Medicine, New Haven, Connecticut, USA
    Genesis 50:453-65. 2012
  5. doi request reprint Cross talk between estradiol and mTOR kinase in the regulation of ovarian granulosa proliferation
    James Yu
    Department of Obstetrics, Gynecology, and Reproductive Sciences, Division of Reproductive Endocrinology, Yale School of Medicine, New Haven, CT 06511, USA
    Reprod Sci 19:143-51. 2012
  6. doi request reprint A putative mitotic checkpoint dependent on mTOR function controls cell proliferation and survival in ovarian granulosa cells
    Aylin Yaba
    Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, New Haven, Connecticut 06510, SA
    Reprod Sci 15:128-38. 2008
  7. doi request reprint The control of oocyte survival by intrinsic and extrinsic factors
    Meltem Kurus
    Division of Reproductive Endocrinology and Infertility, Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, 333 Cedar Street FMB, 329F, New Haven, CT, 06520 8023, USA
    Adv Exp Med Biol 761:7-18. 2013
  8. doi request reprint Intrinsic and extrinsic mechanisms of oocyte loss
    Travis C Thomson
    Department of Obstetrics, Gynecology and Reproductive Sciences, Division of Reproductive Endocrinology and Infertility, Yale School of Medicine, 333 Cedar Street FMB 329F, New Haven, CT 06520, USA
    Mol Hum Reprod 16:916-27. 2010

Collaborators

  • Travis C Thomson
  • James Yu
  • Aylin Yaba
  • Meltem Kurus
  • Mete Hakan Karalok
  • Cengiz Karakaya
  • Grace To
  • Anette Schneemann
  • Corinna Kasiman
  • Travis Thomson
  • Katherine E Fitzpatrick
  • Veronica Bianchi
  • Andrea Borini

Detail Information

Publications8

  1. pmc mTOR controls ovarian follicle growth by regulating granulosa cell proliferation
    James Yu
    Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, New Haven, Connecticut, United States of America
    PLoS ONE 6:e21415. 2011
    ..Implications for the real-time regulation of follicle growth and dominance, including the consequences of increased numbers of aneuploid granulosa cells, are discussed...
  2. doi request reprint Ovarian aging: breaking up is hard to fix
    Joshua Johnson
    Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06510, USA
    Sci Transl Med 5:172fs5. 2013
    ..Accumulation of double-stranded DNA breaks and inhibition of DNA repair contributes to reproductive aging by diminishing ovarian reserves in mice and women...
  3. doi request reprint Ovarian cryopreservation strategies and the fine control of ovarian follicle development in vitro
    Joshua Johnson
    Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, New Haven, Connecticut, USA
    Ann N Y Acad Sci 1221:40-6. 2011
    ..Here, we consider the state of the art of these strategies, and consider the question of whether whole ovary freezing has a place in fertility preservation in the foreseeable future...
  4. doi request reprint Oocyte destruction is activated during viral infection
    Travis C Thomson
    Department of Obstetrics, Gynecology, and Reproductive Sciences Division of Reproductive Endocrinology and Infertility, Yale School of Medicine, New Haven, Connecticut, USA
    Genesis 50:453-65. 2012
    ..The genetic and signaling requirements for oocyte destruction delineated here represent a novel host-virus interaction with implications for the control of both fly and virus populations...
  5. doi request reprint Cross talk between estradiol and mTOR kinase in the regulation of ovarian granulosa proliferation
    James Yu
    Department of Obstetrics, Gynecology, and Reproductive Sciences, Division of Reproductive Endocrinology, Yale School of Medicine, New Haven, CT 06511, USA
    Reprod Sci 19:143-51. 2012
    ..The low concentrations of inhibitors required to increase granulosa proliferation suggest a novel use to support the growth of ovarian follicles...
  6. doi request reprint A putative mitotic checkpoint dependent on mTOR function controls cell proliferation and survival in ovarian granulosa cells
    Aylin Yaba
    Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, New Haven, Connecticut 06510, SA
    Reprod Sci 15:128-38. 2008
    ..Follicles cultured in rapamycin did not undergo atresia. mTOR inhibition results in a reduction in granulosa cell proliferation, supporting a model in which stress and nutritional cues may directly influence ovarian follicle growth...
  7. doi request reprint The control of oocyte survival by intrinsic and extrinsic factors
    Meltem Kurus
    Division of Reproductive Endocrinology and Infertility, Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, 333 Cedar Street FMB, 329F, New Haven, CT, 06520 8023, USA
    Adv Exp Med Biol 761:7-18. 2013
    ..We and others are assessing the role of adjacent somatic (granulosa) cells in follicle survival, determining the relative importance of "oocyte-extrinsic" factors...
  8. doi request reprint Intrinsic and extrinsic mechanisms of oocyte loss
    Travis C Thomson
    Department of Obstetrics, Gynecology and Reproductive Sciences, Division of Reproductive Endocrinology and Infertility, Yale School of Medicine, 333 Cedar Street FMB 329F, New Haven, CT 06520, USA
    Mol Hum Reprod 16:916-27. 2010
    ..RAP treatment of mouse follicles in vitro resulted in phagocytic uptake of the oocyte by granulosa cells as seen in flies. We hypothesize that extrinsic modes of oocyte loss occur in mammals...