Research Topics
| D JainSummaryAffiliation: Yale University Country: USA Publications
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Publications
Molecular evidence for the neoplastic potential of hepatic Von-Meyenburg complexesDhanpat Jain
Department of Pathology, Yale University School of Medicine, New Haven, CT 06520 8023, USA
Appl Immunohistochem Mol Morphol 18:166-71. 2010..The findings also support that VMCs are preneoplastic lesions that could progress to CC with time...
Total fibrous obliteration of main portal vein and portal foam cell venopathy in chronic hepatic allograft rejectionDhanpat Jain
Department of Pathology, Yale University School of Medicine, New Haven, CT 06520 8023, USA
Arch Pathol Lab Med 128:64-7. 2004..Chronic hepatic allograft rejection is characterized by arteriopathy and bile duct loss. Pathology of the portal vein or its branches is not considered to play a major role in chronic rejection...- Diagnosis of hepatocellular carcinoma: fine needle aspiration cytology or needle core biopsyDhanpat Jain
Department of Anatomic Pathology, Yale Univesity School of Medicine, New Haven, Connecticut 06520 8023, USA
J Clin Gastroenterol 35:S101-8. 2002..However, the final choice of the diagnostic procedure should be decided on the basis of working clinical diagnosis and the institutional experience... - Granular cells as a marker of early amiodarone hepatotoxicityD Jain
Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06520 8023, USA
J Clin Gastroenterol 31:241-3. 2000..Pathologists and clinicians should be aware of this subtle histologic finding when looking for evidence to support AD hepatotoxicity... - Relevance of increased lung thallium uptake on stress imaging in patients with unstable angina and non-Q wave myocardial infarction: results of the Thrombolysis in Myocardial Infarction (TIMI)-IIIB StudyD Jain
Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, Connecticut 06510, USA DJ
J Am Coll Cardiol 30:421-9. 1997..This study sought to determine the significance of abnormal thallium-201 (Tl-201) lung uptake on stress imaging in the absence of perfusion abnormalities... - Effects of mental stress on left ventricular and peripheral vascular performance in patients with coronary artery diseaseD Jain
Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA
J Am Coll Cardiol 31:1314-22. 1998..We sought to investigate the mechanism of a mental stress-induced fall in left ventricular ejection fraction (LVEF) in patients with coronary artery disease... - Destabilizing effects of mental stress on ventricular arrhythmias in patients with implantable cardioverter-defibrillatorsR Lampert
Yale University School of Medicine, New Haven, CT 06520, USA
Circulation 101:158-64. 2000.... - Morphology of isolated colonic cryptsM E Robert
Department of Pathology, Yale University School of Medicine, New Haven, Conn 06520 8023, USA
Cells Tissues Organs 168:246-51. 2001..This morphologic analysis will increase our understanding of the observed physiology of isolated colonic crypts... - Bloom syndrome in sibs: first reports of hepatocellular carcinoma and Wilms tumor with documented anaplasia and nephrogenic restsD Jain
Department of Pathology, Yale University School of Medicine, 310 Cedar Street, New Haven, CT 06520-8023, USA
Pediatr Dev Pathol 4:585-9. 2001..These examples expand the spectrum of malignancies occurring in BS to include liver cell neoplasms, and confirm the association of nephrogenic rests with WT, even in the setting of BS... - Liver disease in patients with hereditary hemorrhagic telangiectasiaG Garcia-Tsao
Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn 06520, USA
N Engl J Med 343:931-6. 2000..Liver involvement in patients with this disease has not been fully characterized... - Day-to-day reproducibility of mental stress-induced abnormal left ventricular function response in patients with coronary artery disease and its relationship to autonomic activationD Jain
Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, CT, USA
J Nucl Cardiol 8:347-55. 2001.... - Cardiac pathology of systemic lupus erythematosusD Jain
Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
J Clin Pathol 62:584-92. 2009..While many histopathological findings in lupus-related cardiac diseases are non-specific, there are a few important findings which pathologists should be aware of. This review provides pathological descriptions of these entities... - Use of paclitaxel in patients with pre-existing cardiomyopathy: a review of our experienceA Gollerkeri
Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA
Int J Cancer 93:139-41. 2001..Our experience confirms the results of prior studies that paclitaxel can be safely administered in patients with underlying cardiac dysfunction... - Impact of myocardial perfusion imaging on clinical management and the utilization of hospital resources in suspected acute coronary syndromesB G Abbott
Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, USA
Nucl Med Commun 24:1061-9. 2003.... 
Cytomegalovirus infection masquerading as an ulcerative colitis flare-up: case report and review of the literatureD G Begos
Department of Surgery, Yale University School of Medicine, New Haven, Connecticut, USA
Yale J Biol Med 69:323-8. 1996..Appropriate antiviral therapy appears to eliminate these complications, thus a high index of suspicion for CMV superinfection in cases of IBD refractory to traditional therapy is warranted...- Composite glandular and endocrine tumors of the stomach with pancreatic acinar differentiationDhanpat Jain
Department of Pathology, Yale University School of Medicine, New Haven, CT, USA
Am J Surg Pathol 29:1524-9. 2005..In summary, these tumors represent another distinct type of composite glandular and endocrine gastric neoplasm with pancreatic acinar differentiation... - Ectonucleotidase NTPDase2 is selectively down-regulated in biliary cirrhosisJonathan A Dranoff
Section of Digestive Diseases and Yale Liver Center, Yale University School of Medicine, One Gilbert Street, New Haven, CT 06520, USA
J Investig Med 52:475-82. 2004..The ectonucleotidase* nucleoside triphosphate diphosphohydrolase 2 (NTPDase2) is restricted to portal fibroblasts in the normal liver. However, the fate of NTPDase2 after bile duct ligation (BDL) is unknown... - Adult nesidioblastosis. Clinicopathologic correlation between pre-operative selective arterial calcium stimulation studies and post-operative pathologic findingsBarton Kenney
Department of Pathology and Laboratory Medicine, Yale University School of Medicine, New Haven, CT 06520, USA
JOP 9:504-11. 2008..Overall, seventy-three cases of nesidioblastosis have been described in the English literature since the entity was first described by Laidlaw in 1938, and only a minute fraction of these have occurred in children... - Different cytokeratin and neuronal cell adhesion molecule staining patterns in focal nodular hyperplasia and hepatic adenoma and their significanceAnita Iyer
Department of Pathology, Yale School of Medicine, New Haven, CT 06520, USA
Hum Pathol 39:1370-7. 2008.... - CD8+ but not CD4+ T cells require cognate interactions with target tissues to mediate GVHD across only minor H antigens, whereas both CD4+ and CD8+ T cells require direct leukemic contact to mediate GVLCatherine Matte-Martone
Section of Medical Oncology, Cancer Center, Yale University School of Medicine, New Haven, CT 06520 8032, USA
Blood 111:3884-92. 2008..Thus, CD4 cells use distinct effector mechanisms in GVHD and GVL: direct cytolytic action is required for GVL but not for GVHD. If these noncytolytic pathways can be inhibited, then GVHD might be ameliorated while preserving GVL... - Effector memory CD4+ T cells mediate graft-versus-leukemia without inducing graft-versus-host diseaseHong Zheng
Penn State Milton S Hershey Medical Center, Department of Medicine, Hershey, PA, USA
Blood 111:2476-84. 2008.... - Increased T-cell sinusoidal lymphocytosis in liver biopsies in patients with chronic hepatitis C and mixed cryoglobulinemiaSusanne Carmack
Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06520 8023, USA
Am J Gastroenterol 103:705-11. 2008..This feature may be an important clue to predict the presence of MC, an HCV-associated phenomenon that has important implications for response to treatment and disease progression... - Intraductal papillary cholangiocarcinoma associated with von Meyenberg complexes: a case reportAntonio Galvao Neto
Department of Pathology, Yale School of Medicine, PO Box 208070, New Haven, Connecticut 06520 8070, USA
Dig Dis Sci 52:2643-5. 2007..A possibility that the carcinoma may have originated in a VMC was considered. On follow-up after 12 months the patient is doing well and is without any disease or recurrence... - Gastric siderosis: patterns and significanceEsmeralda C Marginean
Department of Anatomic Pathology, Program in Gastrointestinal Pathology, Yale University School of Medicine, New Haven, CT 06510, USA
Am J Surg Pathol 30:514-20. 2006.... - Histological-hemodynamic correlation in cirrhosis-a histological classification of the severity of cirrhosisSatish Nagula
Section of Digestive Diseases, Department of Internal Medicine, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA
J Hepatol 44:111-7. 2006.... - Liver biopsy: evolving role in the new millenniumHarinath Sheela
Department of Internal Medicine, Section of Digestive Diseases and Liver Center, Yale University School of Medicine, New Haven, CT 06510, USA
J Clin Gastroenterol 39:603-10. 2005..This review discusses the technique, indications, contraindications, and the changing role of liver biopsy in some of the common disorders and the associated controversies... - Clinicopathologic features and survival in fibrolamellar carcinoma: comparison with conventional hepatocellular carcinoma with and without cirrhosisSanjay Kakar
Department of Anatomic Pathology, UCSF VA Medical Center, San Francisco, CA 94121, USA
Mod Pathol 18:1417-23. 2005..The better outcome in fibrolamellar carcinoma appears to be due to the absence of cirrhosis rather than its distinct clinicopathologic features... - Diagnostic intraoperative imprint cytology of a solid pseudopapillary tumor of the pancreasM Rajan Mariappan
Department of Surgical Pathology, Yale University School of Medicine, New Haven, Connecticut 06510, USA
Diagn Cytopathol 32:351-2. 2005 - Ileostomy adenocarcinomas in the setting of ulcerative colitisHardean E Achneck
Department of Surgery, Yale University School of Medicine, New Haven, CT 06520-8023, USA
J Clin Gastroenterol 39:396-400. 2005..The literature on adenocarcinoma arising in the 23 patients with ulcerative colitis who received a Brooke or Kock ileostomy and had no prior history of neoplasm is reviewed... - Rapid progression of autoimmune hepatitis in the background of primary sclerosing cholangitisJoAnn Hong-Curtis
Section of Digestive Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA
J Clin Gastroenterol 38:906-9. 2004..By making the diagnosis of AIH in a patient with well-established PSC, appropriate treatment can be initiated, resulting in the patient's prompt recovery... - Isolation of primary rat liver fibroblastsEmma A Kruglov
Department of Medicine and Yale Liver Center, Yale University School of Medicine, New Haven, Conn 06520, USA
J Investig Med 50:179-84. 2002..CONCLUSION: Primary isolated rat fibroblasts can be produced from a freshly perfused rat liver with a modification of standard cell culture methods. The role of fibroblasts in liver physiology can now be studied directly... - Multiple angiomyolipomata of the liver: a case reportLaura H Tang
Department of Anatomic Pathology, Yale University School of Medicine, New Haven, Connecticut 06511, USA
Mod Pathol 15:167-71. 2002..While the histologic diagnosis of AML in a surgical resection specimen is often straightforward, the radiographic, cytologic and intra-operative interpretation of a case with multiple lesions presents a considerable challenge... - Distinct roles for donor- and host-derived antigen-presenting cells and costimulatory molecules in murine chronic graft-versus-host disease: requirements depend on target organBritt E Anderson
Section of Immunobiology, The Department of Dermatology, Yale University School of Medicine, 333 Cedar St, Box 208035, New Haven, CT 06520 8035, USA
Blood 105:2227-34. 2005..These results identify differences in APC requirements between CD8-mediated aGVHD and CD4-mediated cGVHD. They further highlight donor APCs as additional targets for GVHD therapy...