Farren J Isaacs

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi Precise manipulation of chromosomes in vivo enables genome-wide codon replacement
    Farren J Isaacs
    Department of Genetics, Harvard Medical School, Boston, MA 02115, USA
    Science 333:348-53. 2011
  2. ncbi RNA synthetic biology
    Farren J Isaacs
    Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA
    Nat Biotechnol 24:545-54. 2006
  3. ncbi Programming cells by multiplex genome engineering and accelerated evolution
    Harris H Wang
    Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA
    Nature 460:894-8. 2009
  4. ncbi Molecular biology. Signal processing in single cells
    Farren J Isaacs
    Lipper Center for Computational Genetics and Department of Genetics, Harvard Medical School, Boston, MA 02115, USA
    Science 307:1886-8. 2005
  5. ncbi Engineered riboregulators enable post-transcriptional control of gene expression
    Farren J Isaacs
    Center for BioDynamics and Department of Biomedical Engineering, Boston University, 44 Cummington Street, Boston, Massachusetts 02215, USA
    Nat Biotechnol 22:841-7. 2004

Detail Information

Publications5

  1. ncbi Precise manipulation of chromosomes in vivo enables genome-wide codon replacement
    Farren J Isaacs
    Department of Genetics, Harvard Medical School, Boston, MA 02115, USA
    Science 333:348-53. 2011
    ..Our methods treat the chromosome as both an editable and an evolvable template, permitting the exploration of vast genetic landscapes...
  2. ncbi RNA synthetic biology
    Farren J Isaacs
    Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA
    Nat Biotechnol 24:545-54. 2006
    ..Further challenges include designing RNA molecules to be sensors of intracellular and environmental stimuli, probes to explore the behavior of biological networks and components of engineered cellular control systems...
  3. ncbi Programming cells by multiplex genome engineering and accelerated evolution
    Harris H Wang
    Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA
    Nature 460:894-8. 2009
    ..Our multiplex approach embraces engineering in the context of evolution by expediting the design and evolution of organisms with new and improved properties...
  4. ncbi Molecular biology. Signal processing in single cells
    Farren J Isaacs
    Lipper Center for Computational Genetics and Department of Genetics, Harvard Medical School, Boston, MA 02115, USA
    Science 307:1886-8. 2005
  5. ncbi Engineered riboregulators enable post-transcriptional control of gene expression
    Farren J Isaacs
    Center for BioDynamics and Department of Biomedical Engineering, Boston University, 44 Cummington Street, Boston, Massachusetts 02215, USA
    Nat Biotechnol 22:841-7. 2004
    ....