Karl L Insogna

Summary

Affiliation: Yale University
Country: USA

Publications

  1. doi The effect of proton pump-inhibiting drugs on mineral metabolism
    Karl L Insogna
    Department of Medicine, Endocrine Section, Yale University, New Haven, Connecticut 06520 8020, USA
    Am J Gastroenterol 104:S2-4. 2009
  2. pmc Survey of the enthesopathy of X-linked hypophosphatemia and its characterization in Hyp mice
    Guoying Liang
    Department of Internal Medicine Endocrinology, Yale University, P O Box 208020, New Haven, CT 06520 8020, USA
    Calcif Tissue Int 85:235-46. 2009
  3. pmc Circulating levels of soluble klotho and FGF23 in X-linked hypophosphatemia: circadian variance, effects of treatment, and relationship to parathyroid status
    Thomas O Carpenter
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520 8064, USA
    J Clin Endocrinol Metab 95:E352-7. 2010
  4. ncbi Treatment of osteoporosis and osteopenia in long-term renal transplant patients with alendronate
    Dinna N Cruz
    Yale University School of Medicine, New Haven, CT 06520 8029, USA
    Am J Transplant 2:62-7. 2002
  5. ncbi The expanding role of PI3-kinase in bone
    Lauren H Golden
    Yale University, New Haven, CT 06520, USA
    Bone 34:3-12. 2004
  6. pmc Phosphorus-31 MRI of hard and soft solids using quadratic echo line-narrowing
    Merideth A Frey
    Department of Physics, Yale University, New Haven, CT 06511, USA
    Proc Natl Acad Sci U S A 109:5190-5. 2012
  7. ncbi Meat and soy protein affect calcium homeostasis in healthy women
    Jane E Kerstetter
    Yale New Haven Hospital, New Haven, CT, USA
    J Nutr 136:1890-5. 2006
  8. ncbi Fibroblast growth factor 7: an inhibitor of phosphate transport derived from oncogenic osteomalacia-causing tumors
    Thomas O Carpenter
    Endocrine Sections of the Department of Pediatrics, Yale University School of Medicine, P O Box 208064, New Haven, Connecticut 06520 8064, USA
    J Clin Endocrinol Metab 90:1012-20. 2005
  9. ncbi Overexpression of parathyroid hormone-related protein causes hypercalcemia but not bone metastases in a murine model of mammary tumorigenesis
    John J Wysolmerski
    Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Bone Miner Res 17:1164-70. 2002
  10. pmc A clinician's guide to X-linked hypophosphatemia
    Thomas O Carpenter
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520 8064, USA
    J Bone Miner Res 26:1381-8. 2011

Collaborators

Detail Information

Publications11

  1. doi The effect of proton pump-inhibiting drugs on mineral metabolism
    Karl L Insogna
    Department of Medicine, Endocrine Section, Yale University, New Haven, Connecticut 06520 8020, USA
    Am J Gastroenterol 104:S2-4. 2009
    ..In the long term, this could potentially lead to a negative whole body calcium balance, resulting in higher rates of bone loss and a greater risk of fragility fractures...
  2. pmc Survey of the enthesopathy of X-linked hypophosphatemia and its characterization in Hyp mice
    Guoying Liang
    Department of Internal Medicine Endocrinology, Yale University, P O Box 208020, New Haven, CT 06520 8020, USA
    Calcif Tissue Int 85:235-46. 2009
    ....
  3. pmc Circulating levels of soluble klotho and FGF23 in X-linked hypophosphatemia: circadian variance, effects of treatment, and relationship to parathyroid status
    Thomas O Carpenter
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520 8064, USA
    J Clin Endocrinol Metab 95:E352-7. 2010
    ....
  4. ncbi Treatment of osteoporosis and osteopenia in long-term renal transplant patients with alendronate
    Dinna N Cruz
    Yale University School of Medicine, New Haven, CT 06520 8029, USA
    Am J Transplant 2:62-7. 2002
    ..Whether patients with lesser degrees of bone loss and/or patients without parameters of high bone turnover can also benefit from bisphosphonate therapy deserves further study...
  5. ncbi The expanding role of PI3-kinase in bone
    Lauren H Golden
    Yale University, New Haven, CT 06520, USA
    Bone 34:3-12. 2004
    ..The classification, structure, function, and regulation of PI3-Ks will be reviewed here, with particular emphasis on the role of PI3-K in bone...
  6. pmc Phosphorus-31 MRI of hard and soft solids using quadratic echo line-narrowing
    Merideth A Frey
    Department of Physics, Yale University, New Haven, CT 06511, USA
    Proc Natl Acad Sci U S A 109:5190-5. 2012
    ..Here we demonstrate that this method can be used to carry out three-dimensional MRI of the phosphorus ((31)P) in ex vivo bone and soft tissue samples...
  7. ncbi Meat and soy protein affect calcium homeostasis in healthy women
    Jane E Kerstetter
    Yale New Haven Hospital, New Haven, CT, USA
    J Nutr 136:1890-5. 2006
    ..1) when they consumed the soy diets rather than the meat diets. These data indicate that when soy protein is substituted for meat protein, there is an acute decline in dietary calcium bioavailability...
  8. ncbi Fibroblast growth factor 7: an inhibitor of phosphate transport derived from oncogenic osteomalacia-causing tumors
    Thomas O Carpenter
    Endocrine Sections of the Department of Pediatrics, Yale University School of Medicine, P O Box 208064, New Haven, Connecticut 06520 8064, USA
    J Clin Endocrinol Metab 90:1012-20. 2005
    ..Finally, FGF7 message was confirmed in PCR products of mRNA extracted from fragments of each tumor. Members of the FGF family (other than FGF23) are expressed by OO-associated tumors and may play a role in mediating this syndrome...
  9. ncbi Overexpression of parathyroid hormone-related protein causes hypercalcemia but not bone metastases in a murine model of mammary tumorigenesis
    John J Wysolmerski
    Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Bone Miner Res 17:1164-70. 2002
    ....
  10. pmc A clinician's guide to X-linked hypophosphatemia
    Thomas O Carpenter
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520 8064, USA
    J Bone Miner Res 26:1381-8. 2011
    ..We briefly review the clinical and pathophysiologic features of the disorder and offer this guide in response to the conference recommendation, based on our collective accumulated experience in the management of this complex disorder...
  11. pmc The role of the receptor activator of nuclear factor-kappaB ligand/osteoprotegerin cytokine system in primary hyperparathyroidism
    Inaam A Nakchbandi
    Department of Medicine, Yale University School of Medicine, New Haven, CT 06520, USA
    J Clin Endocrinol Metab 93:967-73. 2008
    ..The objective of this investigation was to examine changes in serum levels of receptor activator of nuclear factor-kappaB ligand and osteoprotegerin (OPG) in primary hyperparathyroidism and their relationship to bone loss...