Research Topics
| P HuiSummaryAffiliation: Yale University Country: USA Publications
| Collaborators
|
Detail Information
Publications
Expression of glypican 3 in placental site trophoblastic tumorRobin J Ou-Yang
Department of Pathology, The Ohio State University Medical Center, 410 W 10th Ave, 401 Doan Hall, Columbus, OH 43210, USA
Diagn Pathol 5:64. 2010....- Pathogenesis of placental site trophoblastic tumor may require the presence of a paternally derived X chromosomeP Hui
Department of Pathology, Yale University Medical School, New Haven, Connecticut, USA
Lab Invest 80:965-72. 2000..Although largely speculative, an active paternal X chromosome may be of importance in the pathogenesis of PSTT... - HMGA proteins in malignant peripheral nerve sheath tumor and synovial sarcoma: preferential expression of HMGA2 in malignant peripheral nerve sheath tumorPei Hui
Department of Pathology, Yale University School of Medicine, New Haven, CT 06520 8023, USA
Mod Pathol 18:1519-26. 2005..In summary, expression of HMGA2 is a feature of MPNST but not of synovial sarcoma and immunohistochemical staining of HMGA2 may be a useful marker to separate malignant peripheral nerve sheath tumor from synovial sarcoma... - Gestational trophoblastic diseases: recent advances in histopathologic diagnosis and related genetic aspectsPei Hui
Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06520 8023, USA
Adv Anat Pathol 12:116-25. 2005..Last, a brief discussion on the role of genetic studies and the future direction of research in elucidating the nature of this intriguing group of lesions is presented... - Absence of Y chromosome in human placental site trophoblastic tumorPei Hui
Department of Pathology, Yale University, New Haven, CT 06520 8023, USA
Mod Pathol 20:1055-60. 2007.... - Minimal uterine serous carcinoma: a clinicopathological study of 40 casesPei Hui
Department of Pathology, Yale University School of Medicine, New Haven, CT 06520 8023, USA
Mod Pathol 18:75-82. 2005..Complete surgical staging is important to predict the prognosis. When the lesion is confined to an endometrial polyp and/or the endometrium proper, the clinical outcome is excellent... - Recurrent endometrial stromal tumors with smooth-muscle differentiation and a protracted clinical coursePei Hui
Department of Pathology, Yale University School of Medicine, Yale New Haven Hospital, BML 250, 310 Cedar Street, New Haven, CT 06520 8023, USA
Nat Clin Pract Oncol 2:588-93, quiz. 2005..She had no significant family history or other gynecological problems. Physical examination revealed tissue fragments and blood clots oozing from the cervical os, and her uterus was diffusely enlarged... - Comparative genomic hybridization study of placental site trophoblastic tumour: a report of four casesPei Hui
Department of Pathology, Weil Medical College of Cornell University, USA
Mod Pathol 17:248-51. 2004..The recurrent chromosomal gain involving chromosomal 21q observed in two of our cases deserves additional studies to ascertain whether it carries any pathobiological significance... - Molecular diagnosis of gestational trophoblastic diseasePei Hui
Department of Pathology, Yale University School of Medicine, BML 254B, 310 Cedar Street, New Haven, CT 06520 8023, USA
Expert Rev Mol Diagn 10:1023-34. 2010..Recently, PCR-based short tandem repeat DNA genotyping has emerged as a powerful diagnostic measure in the workup of gestational trophoblastic disorders, particularly hydatidiform moles... - Intraplacental smooth muscle tumor: a case reportL M Ernst
Department of Anatomic Pathology, Yale University School of Medicine, New Haven, Connecticut, USA
Int J Gynecol Pathol 20:284-8. 2001..Thus, this neoplasm, despite its gross appearance of a primary placental tumor, actually represented an incorporated benign uterine leiomyoma... - Her2/neu extracellular domain shedding in uterine serous carcinoma: implications for immunotherapy with trastuzumabP Todeschini
Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, Room 305 LSOG, PO Box 208063, 333 Cedar Street, New Haven, CT, USA
Br J Cancer 105:1176-82. 2011.... - Epithelioid trophoblastic tumor: comparative genomic hybridization and diagnostic DNA genotypingMina L Xu
Department of Pathology, Yale New Haven Hospital, Yale University School of Medicine, New Haven, CT, USA
Mod Pathol 22:232-8. 2009.... - Improved survival in surgical stage I patients with uterine papillary serous carcinoma (UPSC) treated with adjuvant platinum-based chemotherapyMichael G Kelly
Division of Gynecology Oncology, Department of Obstetrics and Gynecology and Pathology, Yale University School of Medicine, New Haven, CT 06520 8063, USA
Gynecol Oncol 98:353-9. 2005..The purpose of this study was to evaluate the efficacy of adjuvant platinum-based chemotherapy and vaginal cuff radiation in a large cohort of surgical stage I UPSC patients... - Anaplastic oligoastrocytoma in Turcot syndromeJoachim Baehring
Department of Neurology, Yale University School of Medicine, 333 Cedar Street, TMP412, New Haven, CT 06510, USA
J Neurooncol 95:293-8. 2009..Our case adds to the handful of cases published with detailed molecular data previously... - Isolated noncompaction of the ventricular myocardium: clinical and molecular aspects of a rare cardiomyopathyEduardo Zambrano
Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06520-8023, USA
Lab Invest 82:117-22. 2002 - Precise DNA genotyping diagnosis of hydatidiform moleFredilyn Lipata
Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06520 8023, USA
Obstet Gynecol 115:784-94. 2010..To estimate whether tissue DNA genotyping is effective for the confirmation and subclassification of hydatidiform moles... - Lack of genetic association between exaggerated placental site reaction and placental site trophoblastic tumorJorge Dotto
Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Int J Gynecol Pathol 27:562-7. 2008..The assignment of sex chromosomes in our study (XY, 55% and XX, 45%) does not support a neoplastic association between placental site trophoblastic tumor and EPS... - CSF IgH gene rearrangement analysis in isolated post-transplant lymphoproliferative disorder of the central nervous systemJoachim M Baehring
Department of Neurology and Neurosurgery, Yale University School of Medicine, 333 Cedar Street, TMP412, New Haven, CT 06510, USA
J Neurooncol 86:57-60. 2008..We present a case in whom immunoglobulin heavy chain gene rearrangement analysis of cerebrospinal fluid (CSF) was instrumental in establishing the diagnosis... - HER-2/NEU overexpression in vulvar Paget disease: the Yale experienceChristine E Richter
Department of Obstetrics, Gynecology and Reproductive Sciences, Division of Gynecologic Oncology, Yale University School of Medicine, New Haven, Connecticut 06510, USA
J Clin Pathol 63:544-7. 2010..To determine the level of HER-2/neu overexpression in vulvar Paget disease (PD) in order to assess the possibility of using HER-2/neu as a target for the treatment of Paget disease... - Assessment of clonality in melanocytic neviP Hui
Department of Pathology, Yale University School of Medicine, New Haven, Connecticut, USA
J Cutan Pathol 28:140-4. 2001..CONCLUSIONS: These findings suggest that melanocytic nevi are clonal/neoplastic lesions. As such, they cannot be discriminated from melanoma on the basis of clonality... - Genotypic analysis of hydatidiform mole: an accurate and practical method of diagnosisCarlo Bifulco
Programs in Molecular Diagnostics, Department of Pathology, Yale University School of Medicine, New Haven, CT 06520 8023, USA
Am J Surg Pathol 32:445-51. 2008..Our study demonstrates the applicability of DNA genotyping, the molecular approach for the diagnosis, and subtyping of molar pregnancy, to the daily clinical practice... - Epithelioid trophoblastic tumor: clinicopathological features with an emphasis on uterine cervical involvementOluwole Fadare
Department of Pathology, Yale University School of Medicine, New Haven, CT 06520-8023, USA
Mod Pathol 19:75-82. 2006..High index of suspicion and an awareness of elevation of serum chorionic gonadotropin are crucial in reaching a correct diagnosis... - Atypical angiomyolipoma of kidney in a patient with tuberous sclerosis: a case report with p53 gene mutation analysisLinglei Ma
Department of Pathology, Yale University School of Medicine, New Haven, Conn 06510, USA
Arch Pathol Lab Med 129:676-9. 2005..Our finding indicates no definite link between p53 abnormalities and the atypical appearance of AML. To the best of our knowledge, this is the second renal AML case investigated for p53 mutations... - STAT3-mediated signaling in the determination of rod photoreceptor cell fate in mouse retinaSamuel Shao-Min Zhang
Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
Invest Ophthalmol Vis Sci 45:2407-12. 2004..CONCLUSIONS: These results indicate that STAT3, but not MAPK, can critically regulate photoreceptor development during mouse retina development... - Glial heterotopia of the uterine cervix: DNA genotyping confirmation of its fetal originAlexa Siddon
Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06520 8023, USA
Int J Gynecol Pathol 29:394-7. 2010..Genotyping also attested the presence of Klinefelter's syndrome in the first gestation and Down syndrome in the second gestation. Therefore, this molecular case investigation confirms the fetal origin of uterine glial heterotopia... - Differential expression of HMGA1 and HMGA2 in dermatofibroma and dermatofibrosarcoma protuberans: potential diagnostic applications, and comparison with histologic findings, CD34, and factor XIIIa immunoreactivityNing Li
Department of Pathology, Yale University School of Medicine, New Haven, CT 06504 8900, USA
Am J Dermatopathol 26:267-72. 2004..001). We conclude that HMGA1 and HMGA2 expression can be used to distinguish DF from DFSP with a degree of accuracy that is fully equivalent to that of Factor XIIIa and CD34... - Overexpression of EpCAM in uterine serous papillary carcinoma: implications for EpCAM-specific immunotherapy with human monoclonal antibody adecatumumab (MT201)Karim El-Sahwi
Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut 06520 8063, USA
Mol Cancer Ther 9:57-66. 2010..MT201 might represent a novel therapeutic strategy in patients harboring advanced/recurrent or metastatic USPC refractory to standard treatment modalities... - Patients with uterine papillary serous cancers may benefit from adjuvant platinum-based chemoradiationM G Kelly
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Yale University School of Medicine, 333 Cedar Street, PO Box 2080 63, New Haven, CT 06520 8063, USA
Gynecol Oncol 95:469-73. 2004..Only complete surgical staging accurately depicts the extent of this disease. The purpose of this study was to evaluate different therapeutic options in surgically staged patients... - In vitro activity of pertuzumab in combination with trastuzumab in uterine serous papillary adenocarcinomaK El-Sahwi
Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520 8063, USA
Br J Cancer 102:134-43. 2010..We evaluated pertuzumab activity separately or in combination with trastuzumab against primary USPC cell lines expressing different levels of HER2/neu... - MicroRNA signatures differentiate uterine cancer tumor subtypesElena S Ratner
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Yale University School of Medicine, New Haven, CT, USA
Gynecol Oncol 118:251-7. 2010..Our purpose was to identify miRNA profiles of EC subtypes, and to identify miRNAs associated with these subtypes to ultimately understand the different biological behavior between these subtypes... - Real-time quantitative RT-PCR of cyclin D1 mRNA in mantle cell lymphoma: comparison with FISH and immunohistochemistryPei Hui
Department of Laboratory Medicine, Yale University School of Medicine, 333 Cedar Street, P.O. Box 208035, New Haven, CT 06520-8035, USA
Leuk Lymphoma 44:1385-94. 2003.... - Minimal uterine serous carcinoma with extrauterine tumor of identical morphology: an immunohistochemical study of 13 casesZhijie Yan
Department of Pathology, University of Alabama School of Medicine, Birmingham, AL, USA
Appl Immunohistochem Mol Morphol 18:75-9. 2010..In conclusion, our findings support the hypothesis that a transtubal metastatic process is responsible for the extrauterine involvement by minimal endometrial serous carcinoma... - Benign metastasizing leiomyoma: clonality, telomere length and clinicopathologic analysisKurt T Patton
Department of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
Mod Pathol 19:130-40. 2006..Our evidence supports the notion that benign metastasizing leiomyoma is clonally derived from benign-appearing uterine leiomyomas... - Clonal analysis of cutaneous fibrous histiocytoma (dermatofibroma)Pei Hui
Department of Pathology, Yale University School of Medicine, New Haven, CT 06520, USA
J Cutan Pathol 29:385-9. 2002..The fibroblastic form of DF may represent a reactive fibroblastic proliferation. Alternatively, it may represent a true neoplasm whose neoplastic cell type has been obscured by prominent reactive fibroblastic component... - Primary or secondary? Genotyping confirmation of an ovarian primary carcinoid tumorJorge Dotto
Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06520 8023, USA
Int J Gynecol Pathol 27:33-6. 2008..The nature of this primary ovarian tumor was eventually confirmed by demonstration of its germ cell origin through DNA genotyping... - Multiple angiomyolipomata of the liver: a case reportLaura H Tang
Department of Anatomic Pathology, Yale University School of Medicine, New Haven, Connecticut 06511, USA
Mod Pathol 15:167-71. 2002..While the histologic diagnosis of AML in a surgical resection specimen is often straightforward, the radiographic, cytologic and intra-operative interpretation of a case with multiple lesions presents a considerable challenge... - A KRAS-variant in ovarian cancer acts as a genetic marker of cancer riskElena Ratner
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
Cancer Res 70:6509-15. 2010.... - Human herpesvirus-8 is not associated with angiolymphoid hyperplasia with eosinophiliaPradip Bhattacharjee
Department of Dermatology, Yale University School of Medicine, New Haven, CT 06520-8059, USA
J Cutan Pathol 31:612-5. 2004..CONCLUSIONS: Combined data from several, small published studies are equivocal for an association between HHV-8 and ALHE. The results of our large study show no association between HHV-8 and ALHE... - Identification of binding sites of EVI1 in mammalian cellsBogdan Yatsula
Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06510 8023, USA
J Biol Chem 280:30712-22. 2005..In this study we demonstrated for the first time that the N-terminal DNA binding domain of EVI1 has the capacity to bind to endogenous genes. We hypothesized that these genes play a critical role in EVI1-induced transformation... - Pulmonary atresia with intact ventricular septum (PA-IVS) in monozygotic twinsDanielle De Stefano
Department of Laboratory Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA
Am J Med Genet A 146:525-8. 2008 - Assessment of RET/PTC oncogene activation and clonality in thyroid nodules with incomplete morphological evidence of papillary carcinoma: a search for the early precursors of papillary cancerAlfredo Fusco
Centro di Endocrinologia ed Oncologia Sperimentale del Consiglio Nazionale delle Ricerche c o Dipartimento di Biologia e Patologia Cellulare e Molecolare, Universita di Napoli Federico II, Naples, Italy
Am J Pathol 160:2157-67. 2002.... - Synovial sarcoma of the stomach: a clinicopathologic, immunohistochemical, and molecular genetic study of 10 casesHala R Makhlouf
Department of Hepatic, Gastrointestinal Pathology, Armed Forces Institute of Pathology, Washington, DC 20306 6000, USA
Am J Surg Pathol 32:275-81. 2008..Synovial sarcoma rarely occurs as a gastric primary tumor. It has a variable prognosis depending on tumor size and differentiation, and should be considered in the differential diagnosis of KIT-negative gastric spindle cell neoplasms... - Expression of mucins, SIMA, villin, and CDX2 in small-intestinal adenocarcinomaMegan Q Zhang
Lauren V Ackerman Laboratory of Surgical Pathology, Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA
Am J Clin Pathol 128:808-16. 2007..These observations further support the notion that SIA is immunophenotypically distinct from CRC despite their morphologic similarity...