P Hui

Summary

Affiliation: Yale University
Country: USA

Publications

  1. pmc Expression of glypican 3 in placental site trophoblastic tumor
    Robin J Ou-Yang
    Department of Pathology, The Ohio State University Medical Center, 410 W 10th Ave, 401 Doan Hall, Columbus, OH 43210, USA
    Diagn Pathol 5:64. 2010
  2. ncbi request reprint Pathogenesis of placental site trophoblastic tumor may require the presence of a paternally derived X chromosome
    P Hui
    Department of Pathology, Yale University Medical School, New Haven, Connecticut, USA
    Lab Invest 80:965-72. 2000
  3. ncbi request reprint HMGA proteins in malignant peripheral nerve sheath tumor and synovial sarcoma: preferential expression of HMGA2 in malignant peripheral nerve sheath tumor
    Pei Hui
    Department of Pathology, Yale University School of Medicine, New Haven, CT 06520 8023, USA
    Mod Pathol 18:1519-26. 2005
  4. ncbi request reprint Absence of Y chromosome in human placental site trophoblastic tumor
    Pei Hui
    Department of Pathology, Yale University, New Haven, CT 06520 8023, USA
    Mod Pathol 20:1055-60. 2007
  5. ncbi request reprint Gestational trophoblastic diseases: recent advances in histopathologic diagnosis and related genetic aspects
    Pei Hui
    Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06520 8023, USA
    Adv Anat Pathol 12:116-25. 2005
  6. ncbi request reprint Minimal uterine serous carcinoma: a clinicopathological study of 40 cases
    Pei Hui
    Department of Pathology, Yale University School of Medicine, New Haven, CT 06520 8023, USA
    Mod Pathol 18:75-82. 2005
  7. ncbi request reprint Recurrent endometrial stromal tumors with smooth-muscle differentiation and a protracted clinical course
    Pei Hui
    Department of Pathology, Yale University School of Medicine, Yale New Haven Hospital, BML 250, 310 Cedar Street, New Haven, CT 06520 8023, USA
    Nat Clin Pract Oncol 2:588-93, quiz. 2005
  8. ncbi request reprint Comparative genomic hybridization study of placental site trophoblastic tumour: a report of four cases
    Pei Hui
    Department of Pathology, Weil Medical College of Cornell University, USA
    Mod Pathol 17:248-51. 2004
  9. doi request reprint Molecular diagnosis of gestational trophoblastic disease
    Pei Hui
    Department of Pathology, Yale University School of Medicine, BML 254B, 310 Cedar Street, New Haven, CT 06520 8023, USA
    Expert Rev Mol Diagn 10:1023-34. 2010
  10. ncbi request reprint Intraplacental smooth muscle tumor: a case report
    L M Ernst
    Department of Anatomic Pathology, Yale University School of Medicine, New Haven, Connecticut, USA
    Int J Gynecol Pathol 20:284-8. 2001

Collaborators

Detail Information

Publications44

  1. pmc Expression of glypican 3 in placental site trophoblastic tumor
    Robin J Ou-Yang
    Department of Pathology, The Ohio State University Medical Center, 410 W 10th Ave, 401 Doan Hall, Columbus, OH 43210, USA
    Diagn Pathol 5:64. 2010
    ....
  2. ncbi request reprint Pathogenesis of placental site trophoblastic tumor may require the presence of a paternally derived X chromosome
    P Hui
    Department of Pathology, Yale University Medical School, New Haven, Connecticut, USA
    Lab Invest 80:965-72. 2000
    ..Although largely speculative, an active paternal X chromosome may be of importance in the pathogenesis of PSTT...
  3. ncbi request reprint HMGA proteins in malignant peripheral nerve sheath tumor and synovial sarcoma: preferential expression of HMGA2 in malignant peripheral nerve sheath tumor
    Pei Hui
    Department of Pathology, Yale University School of Medicine, New Haven, CT 06520 8023, USA
    Mod Pathol 18:1519-26. 2005
    ..In summary, expression of HMGA2 is a feature of MPNST but not of synovial sarcoma and immunohistochemical staining of HMGA2 may be a useful marker to separate malignant peripheral nerve sheath tumor from synovial sarcoma...
  4. ncbi request reprint Absence of Y chromosome in human placental site trophoblastic tumor
    Pei Hui
    Department of Pathology, Yale University, New Haven, CT 06520 8023, USA
    Mod Pathol 20:1055-60. 2007
    ....
  5. ncbi request reprint Gestational trophoblastic diseases: recent advances in histopathologic diagnosis and related genetic aspects
    Pei Hui
    Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06520 8023, USA
    Adv Anat Pathol 12:116-25. 2005
    ..Last, a brief discussion on the role of genetic studies and the future direction of research in elucidating the nature of this intriguing group of lesions is presented...
  6. ncbi request reprint Minimal uterine serous carcinoma: a clinicopathological study of 40 cases
    Pei Hui
    Department of Pathology, Yale University School of Medicine, New Haven, CT 06520 8023, USA
    Mod Pathol 18:75-82. 2005
    ..Complete surgical staging is important to predict the prognosis. When the lesion is confined to an endometrial polyp and/or the endometrium proper, the clinical outcome is excellent...
  7. ncbi request reprint Recurrent endometrial stromal tumors with smooth-muscle differentiation and a protracted clinical course
    Pei Hui
    Department of Pathology, Yale University School of Medicine, Yale New Haven Hospital, BML 250, 310 Cedar Street, New Haven, CT 06520 8023, USA
    Nat Clin Pract Oncol 2:588-93, quiz. 2005
    ..She had no significant family history or other gynecological problems. Physical examination revealed tissue fragments and blood clots oozing from the cervical os, and her uterus was diffusely enlarged...
  8. ncbi request reprint Comparative genomic hybridization study of placental site trophoblastic tumour: a report of four cases
    Pei Hui
    Department of Pathology, Weil Medical College of Cornell University, USA
    Mod Pathol 17:248-51. 2004
    ..The recurrent chromosomal gain involving chromosomal 21q observed in two of our cases deserves additional studies to ascertain whether it carries any pathobiological significance...
  9. doi request reprint Molecular diagnosis of gestational trophoblastic disease
    Pei Hui
    Department of Pathology, Yale University School of Medicine, BML 254B, 310 Cedar Street, New Haven, CT 06520 8023, USA
    Expert Rev Mol Diagn 10:1023-34. 2010
    ..Recently, PCR-based short tandem repeat DNA genotyping has emerged as a powerful diagnostic measure in the workup of gestational trophoblastic disorders, particularly hydatidiform moles...
  10. ncbi request reprint Intraplacental smooth muscle tumor: a case report
    L M Ernst
    Department of Anatomic Pathology, Yale University School of Medicine, New Haven, Connecticut, USA
    Int J Gynecol Pathol 20:284-8. 2001
    ..Thus, this neoplasm, despite its gross appearance of a primary placental tumor, actually represented an incorporated benign uterine leiomyoma...
  11. pmc Her2/neu extracellular domain shedding in uterine serous carcinoma: implications for immunotherapy with trastuzumab
    P Todeschini
    Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, Room 305 LSOG, PO Box 208063, 333 Cedar Street, New Haven, CT, USA
    Br J Cancer 105:1176-82. 2011
    ....
  12. ncbi request reprint Improved survival in surgical stage I patients with uterine papillary serous carcinoma (UPSC) treated with adjuvant platinum-based chemotherapy
    Michael G Kelly
    Division of Gynecology Oncology, Department of Obstetrics and Gynecology and Pathology, Yale University School of Medicine, New Haven, CT 06520 8063, USA
    Gynecol Oncol 98:353-9. 2005
    ..The purpose of this study was to evaluate the efficacy of adjuvant platinum-based chemotherapy and vaginal cuff radiation in a large cohort of surgical stage I UPSC patients...
  13. ncbi request reprint Isolated noncompaction of the ventricular myocardium: clinical and molecular aspects of a rare cardiomyopathy
    Eduardo Zambrano
    Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06520 8023, USA
    Lab Invest 82:117-22. 2002
  14. doi request reprint Anaplastic oligoastrocytoma in Turcot syndrome
    Joachim Baehring
    Department of Neurology, Yale University School of Medicine, 333 Cedar Street, TMP412, New Haven, CT 06510, USA
    J Neurooncol 95:293-8. 2009
    ..Our case adds to the handful of cases published with detailed molecular data previously...
  15. ncbi request reprint CSF IgH gene rearrangement analysis in isolated post-transplant lymphoproliferative disorder of the central nervous system
    Joachim M Baehring
    Department of Neurology and Neurosurgery, Yale University School of Medicine, 333 Cedar Street, TMP412, New Haven, CT 06510, USA
    J Neurooncol 86:57-60. 2008
    ..We present a case in whom immunoglobulin heavy chain gene rearrangement analysis of cerebrospinal fluid (CSF) was instrumental in establishing the diagnosis...
  16. doi request reprint Precise DNA genotyping diagnosis of hydatidiform mole
    Fredilyn Lipata
    Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06520 8023, USA
    Obstet Gynecol 115:784-94. 2010
    ..To estimate whether tissue DNA genotyping is effective for the confirmation and subclassification of hydatidiform moles...
  17. doi request reprint Lack of genetic association between exaggerated placental site reaction and placental site trophoblastic tumor
    Jorge Dotto
    Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Int J Gynecol Pathol 27:562-7. 2008
    ..The assignment of sex chromosomes in our study (XY, 55% and XX, 45%) does not support a neoplastic association between placental site trophoblastic tumor and EPS...
  18. doi request reprint Epithelioid trophoblastic tumor: comparative genomic hybridization and diagnostic DNA genotyping
    Mina L Xu
    Department of Pathology, Yale New Haven Hospital, Yale University School of Medicine, New Haven, CT, USA
    Mod Pathol 22:232-8. 2009
    ....
  19. doi request reprint HER-2/NEU overexpression in vulvar Paget disease: the Yale experience
    Christine E Richter
    Department of Obstetrics, Gynecology and Reproductive Sciences, Division of Gynecologic Oncology, Yale University School of Medicine, New Haven, Connecticut 06510, USA
    J Clin Pathol 63:544-7. 2010
    ..To determine the level of HER-2/neu overexpression in vulvar Paget disease (PD) in order to assess the possibility of using HER-2/neu as a target for the treatment of Paget disease...
  20. ncbi request reprint Assessment of clonality in melanocytic nevi
    P Hui
    Department of Pathology, Yale University School of Medicine, New Haven, Connecticut, USA
    J Cutan Pathol 28:140-4. 2001
    ..CONCLUSIONS: These findings suggest that melanocytic nevi are clonal/neoplastic lesions. As such, they cannot be discriminated from melanoma on the basis of clonality...
  21. doi request reprint Genotypic analysis of hydatidiform mole: an accurate and practical method of diagnosis
    Carlo Bifulco
    Programs in Molecular Diagnostics, Department of Pathology, Yale University School of Medicine, New Haven, CT 06520 8023, USA
    Am J Surg Pathol 32:445-51. 2008
    ..Our study demonstrates the applicability of DNA genotyping, the molecular approach for the diagnosis, and subtyping of molar pregnancy, to the daily clinical practice...
  22. ncbi request reprint Epithelioid trophoblastic tumor: clinicopathological features with an emphasis on uterine cervical involvement
    Oluwole Fadare
    Department of Pathology, Yale University School of Medicine, New Haven, CT 06520 8023, USA
    Mod Pathol 19:75-82. 2006
    ..High index of suspicion and an awareness of elevation of serum chorionic gonadotropin are crucial in reaching a correct diagnosis...
  23. doi request reprint Glial heterotopia of the uterine cervix: DNA genotyping confirmation of its fetal origin
    Alexa Siddon
    Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06520 8023, USA
    Int J Gynecol Pathol 29:394-7. 2010
    ..Genotyping also attested the presence of Klinefelter's syndrome in the first gestation and Down syndrome in the second gestation. Therefore, this molecular case investigation confirms the fetal origin of uterine glial heterotopia...
  24. ncbi request reprint Atypical angiomyolipoma of kidney in a patient with tuberous sclerosis: a case report with p53 gene mutation analysis
    Linglei Ma
    Department of Pathology, Yale University School of Medicine, New Haven, Conn 06510, USA
    Arch Pathol Lab Med 129:676-9. 2005
    ..Our finding indicates no definite link between p53 abnormalities and the atypical appearance of AML. To the best of our knowledge, this is the second renal AML case investigated for p53 mutations...
  25. ncbi request reprint STAT3-mediated signaling in the determination of rod photoreceptor cell fate in mouse retina
    Samuel Shao Min Zhang
    Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Invest Ophthalmol Vis Sci 45:2407-12. 2004
    ..The purpose of this study was to determine the intracellular pathways by which ciliary neurotrophic factor (CNTF) and leukemia inhibitory factor (LIF) negatively regulate the development of rod photoreceptors in the mouse retina...
  26. ncbi request reprint Differential expression of HMGA1 and HMGA2 in dermatofibroma and dermatofibrosarcoma protuberans: potential diagnostic applications, and comparison with histologic findings, CD34, and factor XIIIa immunoreactivity
    Ning Li
    Department of Pathology, Yale University School of Medicine, New Haven, CT 06504 8900, USA
    Am J Dermatopathol 26:267-72. 2004
    ..001). We conclude that HMGA1 and HMGA2 expression can be used to distinguish DF from DFSP with a degree of accuracy that is fully equivalent to that of Factor XIIIa and CD34...
  27. pmc Overexpression of EpCAM in uterine serous papillary carcinoma: implications for EpCAM-specific immunotherapy with human monoclonal antibody adecatumumab (MT201)
    Karim El-Sahwi
    Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut 06520 8063, USA
    Mol Cancer Ther 9:57-66. 2010
    ..MT201 might represent a novel therapeutic strategy in patients harboring advanced/recurrent or metastatic USPC refractory to standard treatment modalities...
  28. pmc Relapsing and remitting severe hypoglycemia due to a monoclonal anti-insulin antibody heralding a case of multiple myeloma
    F Waldron-Lynch
    Department of Internal Medicine, Section of Endocrinology and Metabolism, Yale University School of Medicine, New Haven, Connecticut 06510, USA
    J Clin Endocrinol Metab 97:4317-23. 2012
    ..We report a novel case of insulin autoimmune syndrome (IAS) presenting with hypoglycemia due to production of a monoclonal anti-insulin antibody in a patient subsequently found to have multiple myeloma (MM)...
  29. pmc In vitro activity of pertuzumab in combination with trastuzumab in uterine serous papillary adenocarcinoma
    K El-Sahwi
    Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520 8063, USA
    Br J Cancer 102:134-43. 2010
    ..We evaluated pertuzumab activity separately or in combination with trastuzumab against primary USPC cell lines expressing different levels of HER2/neu...
  30. ncbi request reprint Patients with uterine papillary serous cancers may benefit from adjuvant platinum-based chemoradiation
    M G Kelly
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Yale University School of Medicine, 333 Cedar Street, PO Box 2080 63, New Haven, CT 06520 8063, USA
    Gynecol Oncol 95:469-73. 2004
    ..Only complete surgical staging accurately depicts the extent of this disease. The purpose of this study was to evaluate different therapeutic options in surgically staged patients...
  31. ncbi request reprint Real-time quantitative RT-PCR of cyclin D1 mRNA in mantle cell lymphoma: comparison with FISH and immunohistochemistry
    Pei Hui
    Department of Laboratory Medicine, Yale University School of Medicine, 333 Cedar Street, P O Box 208035, New Haven, CT 06520 8035, USA
    Leuk Lymphoma 44:1385-94. 2003
    ....
  32. ncbi request reprint Benign metastasizing leiomyoma: clonality, telomere length and clinicopathologic analysis
    Kurt T Patton
    Department of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
    Mod Pathol 19:130-40. 2006
    ..Our evidence supports the notion that benign metastasizing leiomyoma is clonally derived from benign-appearing uterine leiomyomas...
  33. doi request reprint Minimal uterine serous carcinoma with extrauterine tumor of identical morphology: an immunohistochemical study of 13 cases
    Zhijie Yan
    Department of Pathology, University of Alabama School of Medicine, Birmingham, AL, USA
    Appl Immunohistochem Mol Morphol 18:75-9. 2010
    ..In conclusion, our findings support the hypothesis that a transtubal metastatic process is responsible for the extrauterine involvement by minimal endometrial serous carcinoma...
  34. ncbi request reprint Clonal analysis of cutaneous fibrous histiocytoma (dermatofibroma)
    Pei Hui
    Department of Pathology, Yale University School of Medicine, New Haven, CT 06520, USA
    J Cutan Pathol 29:385-9. 2002
    ..Diagnostically, the most important question faced is the distinction from dermatofibrosarcoma protuberans (DFSP). Misdiagnosis can occur, as the early phase of DFSP can simulate DF, particularly the deep and cellular forms of DF...
  35. ncbi request reprint Primary or secondary? Genotyping confirmation of an ovarian primary carcinoid tumor
    Jorge Dotto
    Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06520 8023, USA
    Int J Gynecol Pathol 27:33-6. 2008
    ..The nature of this primary ovarian tumor was eventually confirmed by demonstration of its germ cell origin through DNA genotyping...
  36. pmc MicroRNA signatures differentiate uterine cancer tumor subtypes
    Elena S Ratner
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Yale University School of Medicine, New Haven, CT, USA
    Gynecol Oncol 118:251-7. 2010
    ..Our purpose was to identify miRNA profiles of EC subtypes, and to identify miRNAs associated with these subtypes to ultimately understand the different biological behavior between these subtypes...
  37. ncbi request reprint Multiple angiomyolipomata of the liver: a case report
    Laura H Tang
    Department of Anatomic Pathology, Yale University School of Medicine, New Haven, Connecticut 06511, USA
    Mod Pathol 15:167-71. 2002
    ..While the histologic diagnosis of AML in a surgical resection specimen is often straightforward, the radiographic, cytologic and intra-operative interpretation of a case with multiple lesions presents a considerable challenge...
  38. pmc A KRAS-variant in ovarian cancer acts as a genetic marker of cancer risk
    Elena Ratner
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Cancer Res 70:6509-15. 2010
    ....
  39. ncbi request reprint Identification of binding sites of EVI1 in mammalian cells
    Bogdan Yatsula
    Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06510 8023, USA
    J Biol Chem 280:30712-22. 2005
    ..In this study we demonstrated for the first time that the N-terminal DNA binding domain of EVI1 has the capacity to bind to endogenous genes. We hypothesized that these genes play a critical role in EVI1-induced transformation...
  40. ncbi request reprint Human herpesvirus-8 is not associated with angiolymphoid hyperplasia with eosinophilia
    Pradip Bhattacharjee
    Department of Dermatology, Yale University School of Medicine, New Haven, CT 06520 8059, USA
    J Cutan Pathol 31:612-5. 2004
    ..It has been well documented in the literature that human herpesvirus-8 (HHV-8) DNA is present in the majority of cases of Kaposi's sarcoma; however, there is contradictory data regarding the association of this virus with ALHE...
  41. doi request reprint Pulmonary atresia with intact ventricular septum (PA-IVS) in monozygotic twins
    Danielle De Stefano
    Department of Laboratory Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Am J Med Genet A 146:525-8. 2008
  42. pmc Assessment of RET/PTC oncogene activation and clonality in thyroid nodules with incomplete morphological evidence of papillary carcinoma: a search for the early precursors of papillary cancer
    Alfredo Fusco
    Centro di Endocrinologia ed Oncologia Sperimentale del Consiglio Nazionale delle Ricerche c o Dipartimento di Biologia e Patologia Cellulare e Molecolare, Universita di Napoli Federico II, Naples, Italy
    Am J Pathol 160:2157-67. 2002
    ....
  43. doi request reprint Synovial sarcoma of the stomach: a clinicopathologic, immunohistochemical, and molecular genetic study of 10 cases
    Hala R Makhlouf
    Department of Hepatic, Gastrointestinal Pathology, Armed Forces Institute of Pathology, Washington, DC 20306 6000, USA
    Am J Surg Pathol 32:275-81. 2008
    ..Synovial sarcoma rarely occurs as a gastric primary tumor. It has a variable prognosis depending on tumor size and differentiation, and should be considered in the differential diagnosis of KIT-negative gastric spindle cell neoplasms...
  44. ncbi request reprint Expression of mucins, SIMA, villin, and CDX2 in small-intestinal adenocarcinoma
    Megan Q Zhang
    Lauren V Ackerman Laboratory of Surgical Pathology, Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA
    Am J Clin Pathol 128:808-16. 2007
    ..These observations further support the notion that SIA is immunophenotypically distinct from CRC despite their morphologic similarity...