Research Topics
Species | Matthew R HodgesSummaryAffiliation: Yale University Country: USA Publications
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Detail Information
Publications
Defects in breathing and thermoregulation in mice with near-complete absence of central serotonin neuronsMatthew R Hodges
Department of Neurology, Yale University, New Haven, Connecticut 06520, USA
J Neurosci 28:2495-505. 2008..We conclude that the proper function of the 5-HT system is particularly important under conditions of environmental stress and contributes significantly to the hypercapnic ventilatory response and thermoregulatory cold defense...
Transgenic mice lacking serotonin neurons have severe apnea and high mortality during developmentMatthew R Hodges
Departments of Neurology and Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT 06510, USA
J Neurosci 29:10341-9. 2009..These findings provide insight into the mechanisms of sudden infant death syndrome, which has been associated with abnormalities of 5-HT neurons and of cardiorespiratory control...
Interaction between defects in ventilatory and thermoregulatory control in mice lacking 5-HT neuronsMatthew R Hodges
Department of Neurology, Yale University School of Medicine, New Haven, CT 06520, United States
Respir Physiol Neurobiol 164:350-7. 2008....
Carotid body denervation alters ventilatory responses to ibotenic acid injections or focal acidosis in the medullary rapheM R Hodges
Dept of Neurology, Yale University School of Medicine, New Haven, CT 06520, USA
J Appl Physiol 98:1234-42. 2005....
Contributions of 5-HT neurons to respiratory control: neuromodulatory and trophic effectsMatthew R Hodges
Department of Neurology and Cellular and Molecular Physiology, Yale School of Medicine, New Haven, CT 06520, USA
Respir Physiol Neurobiol 164:222-32. 2008..Future directions of study are also discussed...
Altered ventilatory and thermoregulatory control in male and female adult Pet-1 null miceMatthew R Hodges
Departments of Neurology and Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT 06520, United States
Respir Physiol Neurobiol 177:133-40. 2011....
Homing in on the specific phenotype(s) of central respiratory chemoreceptorsG B Richerson
Department of Neurology, Yale University School of Medicine, New Haven, CT 06520 8018, USA
Exp Physiol 90:259-66; discussion 266-9. 2005..Future work will need to focus on which of the candidates are indeed chemoreceptors, what percentage of the overall response each one contributes, and how this percentage varies under different conditions...
Effects on breathing of focal acidosis at multiple medullary raphe sites in awake goatsM R Hodges
Department of Physiology, Medical College of Wisconsin, USA
J Appl Physiol 97:2303-9. 2004..Additionally, focal acidification of raphe chemoreceptors appears to activate an established thermogenic response needed to offset the increased heat loss associated with the CO(2) hyperpnea...
Transient attenuation of CO2 sensitivity after neurotoxic lesions in the medullary raphe area of awake goatsM R Hodges
Dept of Physiology, Medical College of Wisconsin, USA
J Appl Physiol 97:2236-47. 2004....
Ventilatory phenotypes among four strains of adult ratsMatthew R Hodges
Department of Physiology, Medical College of Wisconsin, Wisconsin 53226, USA
J Appl Physiol 93:974-83. 2002..Finally, the data establish a foundation for physiological genomic studies aimed at elucidating the genetics of these ventilatory control mechanisms...
