Shizhong Han

Summary

Affiliation: Yale University
Country: USA

Publications

  1. pmc Ordered subset linkage analysis based on admixture proportion identifies new linkage evidence for alcohol dependence in African-Americans
    Shizhong Han
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut and VA CT Healthcare Center 116A2, 950 Campbell Avenue, West Haven, CT, USA
    Hum Genet 132:397-403. 2013
  2. doi Autosomal linkage scan for loci predisposing to comorbid dependence on multiple substances
    Bao zhu Yang
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
    Am J Med Genet B Neuropsychiatr Genet 159:361-9. 2012
  3. pmc Linkage analysis followed by association show NRG1 associated with cannabis dependence in African Americans
    Shizhong Han
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut Veterans Affairs Connecticut Healthcare Center, West Haven, CT 06516, USA
    Biol Psychiatry 72:637-44. 2012
  4. pmc Association of CHRNA4 polymorphisms with smoking behavior in two populations
    Shizhong Han
    Department of Psychiatry, Division of Human Genetics, Yale University School of Medicine, New Haven, Connecticut, USA
    Am J Med Genet B Neuropsychiatr Genet 156:421-9. 2011
  5. pmc Integrating GWASs and human protein interaction networks identifies a gene subnetwork underlying alcohol dependence
    Shizhong Han
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, USA Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA 55242, USA Electronic address
    Am J Hum Genet 93:1027-34. 2013
  6. doi Association of the HTR2A gene with alcohol and heroin abuse
    Jian Cao
    Department of Pathology, School of Medicine, Yale University, New Haven, CT, 06511, USA
    Hum Genet 133:357-65. 2014
  7. pmc A genomewide linkage scan of cocaine dependence and major depressive episode in two populations
    Bao zhu Yang
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Neuropsychopharmacology 36:2422-30. 2011
  8. pmc Variant callers for next-generation sequencing data: a comparison study
    Xiangtao Liu
    Department of Psychiatry, Division of Human Genetics, Yale University School of Medicine, New Haven, Connecticut, United States of America VA CT Health Care Center, West Haven, Connecticut, United States of America
    PLoS ONE 8:e75619. 2013
  9. pmc Meta-analysis of 15 genome-wide linkage scans of smoking behavior
    Shizhong Han
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06516, USA
    Biol Psychiatry 67:12-9. 2010

Detail Information

Publications9

  1. pmc Ordered subset linkage analysis based on admixture proportion identifies new linkage evidence for alcohol dependence in African-Americans
    Shizhong Han
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut and VA CT Healthcare Center 116A2, 950 Campbell Avenue, West Haven, CT, USA
    Hum Genet 132:397-403. 2013
    ..This approach could be applied to any linkage analysis for complex traits conducted in an admixed population...
  2. doi Autosomal linkage scan for loci predisposing to comorbid dependence on multiple substances
    Bao zhu Yang
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
    Am J Med Genet B Neuropsychiatr Genet 159:361-9. 2012
    ..This is the first linkage evidence supporting existence of genetic loci influencing risk for several comorbid disorders simultaneously in two major US populations...
  3. pmc Linkage analysis followed by association show NRG1 associated with cannabis dependence in African Americans
    Shizhong Han
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut Veterans Affairs Connecticut Healthcare Center, West Haven, CT 06516, USA
    Biol Psychiatry 72:637-44. 2012
    ..A genetic contribution to cannabis dependence (CaD) has been established but susceptibility genes for CaD remain largely unknown...
  4. pmc Association of CHRNA4 polymorphisms with smoking behavior in two populations
    Shizhong Han
    Department of Psychiatry, Division of Human Genetics, Yale University School of Medicine, New Haven, Connecticut, USA
    Am J Med Genet B Neuropsychiatr Genet 156:421-9. 2011
    ..033). In summary, our study supports association between CHRNA4 common variation and ND in AA and EA samples. Additional studies will be necessary to evaluate the role of rare variants at CHRNA4 for ND...
  5. pmc Integrating GWASs and human protein interaction networks identifies a gene subnetwork underlying alcohol dependence
    Shizhong Han
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, USA Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA 55242, USA Electronic address
    Am J Hum Genet 93:1027-34. 2013
    ..In conclusion, we identified a gene subnetwork underlying AD that is biologically meaningful and highly reproducible, providing important clues for future research into AD etiology and treatment. ..
  6. doi Association of the HTR2A gene with alcohol and heroin abuse
    Jian Cao
    Department of Pathology, School of Medicine, Yale University, New Haven, CT, 06511, USA
    Hum Genet 133:357-65. 2014
    ..The meta-analysis supports a contribution of the HTR2A gene to the susceptibility to substance use disorders, particularly alcohol dependence...
  7. pmc A genomewide linkage scan of cocaine dependence and major depressive episode in two populations
    Bao zhu Yang
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Neuropsychopharmacology 36:2422-30. 2011
    ..Replication of the linkage findings in other populations is warranted, as is a focused analysis of the genes located in the linkage regions implicated here...
  8. pmc Variant callers for next-generation sequencing data: a comparison study
    Xiangtao Liu
    Department of Psychiatry, Division of Human Genetics, Yale University School of Medicine, New Haven, Connecticut, United States of America VA CT Health Care Center, West Haven, Connecticut, United States of America
    PLoS ONE 8:e75619. 2013
    ..87% and 99.82%, respectively. In conclusion, GATK showed several advantages over other variant callers for general purpose NGS analyses. The GATK pipelines we developed perform very well. ..
  9. pmc Meta-analysis of 15 genome-wide linkage scans of smoking behavior
    Shizhong Han
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06516, USA
    Biol Psychiatry 67:12-9. 2010
    ..Numerous putative susceptibility loci have been identified, but only a few of these were replicated in independent studies...