Stephanie Halene

Summary

Affiliation: Yale University
Country: USA

Publications

  1. pmc C/EBPepsilon directs granulocytic-vs-monocytic lineage determination and confers chemotactic function via Hlx
    Stephanie Halene
    Section of Hematology, Department of Internal Medicine and Yale Cancer Center, Yale University School of Medicine, New Haven, CT 06520 8073, USA
    Exp Hematol 38:90-103. 2010
  2. pmc Evidence-based genomic diagnosis characterized chromosomal and cryptic imbalances in 30 elderly patients with myelodysplastic syndrome and acute myeloid leukemia
    Renu Bajaj
    Molecular Cytogenetics Laboratory, Department of Genetics, Yale University School of Medicine, 333 Cedar Street, New Haven, CT, USA
    Mol Cytogenet 4:3. 2011
  3. pmc Serum response factor is an essential transcription factor in megakaryocytic maturation
    Stephanie Halene
    Department of Internal Medicine and Yale Cancer Center, Section of Hematology, 333 Cedar Street, New Haven, CT 06520, USA
    Blood 116:1942-50. 2010
  4. pmc MKL1 and MKL2 play redundant and crucial roles in megakaryocyte maturation and platelet formation
    ELENOE C SMITH
    Department of Cell Biology, Yale University School of Medicine, New Haven, CT, USA
    Blood 120:2317-29. 2012
  5. pmc Complex oncogene dependence in microRNA-125a-induced myeloproliferative neoplasms
    Shangqin Guo
    Department of Genetics, Yale University School of Medicine, New Haven, CT 06520, USA
    Proc Natl Acad Sci U S A 109:16636-41. 2012
  6. pmc Role of RhoA-specific guanine exchange factors in regulation of endomitosis in megakaryocytes
    Yuan Gao
    Department of Laboratory Medicine, Yale University, New Haven, CT 06520, USA
    Dev Cell 22:573-84. 2012
  7. pmc Different roles of G protein subunits beta1 and beta2 in neutrophil function revealed by gene expression silencing in primary mouse neutrophils
    Yong Zhang
    Department of Pharmacology, Yale School of Medicine, New Haven, Connecticut 06520, USA
    J Biol Chem 285:24805-14. 2010

Collaborators

Detail Information

Publications7

  1. pmc C/EBPepsilon directs granulocytic-vs-monocytic lineage determination and confers chemotactic function via Hlx
    Stephanie Halene
    Section of Hematology, Department of Internal Medicine and Yale Cancer Center, Yale University School of Medicine, New Haven, CT 06520 8073, USA
    Exp Hematol 38:90-103. 2010
    ..Although the specific granule deficiency phenotype has been replicated in C/EBPepsilon(-/-) (knockout [KO]) mice, the mechanisms by which C/EBPepsilon mutations act to decrease neutrophil function are not entirely clear...
  2. pmc Evidence-based genomic diagnosis characterized chromosomal and cryptic imbalances in 30 elderly patients with myelodysplastic syndrome and acute myeloid leukemia
    Renu Bajaj
    Molecular Cytogenetics Laboratory, Department of Genetics, Yale University School of Medicine, 333 Cedar Street, New Haven, CT, USA
    Mol Cytogenet 4:3. 2011
    ..abstract:..
  3. pmc Serum response factor is an essential transcription factor in megakaryocytic maturation
    Stephanie Halene
    Department of Internal Medicine and Yale Cancer Center, Section of Hematology, 333 Cedar Street, New Haven, CT 06520, USA
    Blood 116:1942-50. 2010
    ..Critical actin cytoskeletal genes are down-regulated in KO megakaryocytes. Thus, Srf is required for normal megakaryocyte maturation and platelet production partly because of regulation of cytoskeletal genes...
  4. pmc MKL1 and MKL2 play redundant and crucial roles in megakaryocyte maturation and platelet formation
    ELENOE C SMITH
    Department of Cell Biology, Yale University School of Medicine, New Haven, CT, USA
    Blood 120:2317-29. 2012
    ....
  5. pmc Complex oncogene dependence in microRNA-125a-induced myeloproliferative neoplasms
    Shangqin Guo
    Department of Genetics, Yale University School of Medicine, New Haven, CT 06520, USA
    Proc Natl Acad Sci U S A 109:16636-41. 2012
    ..Our data demonstrate that miR-125a-induced MPN is addicted to its sustained overexpression, and highlight the complex nature of oncogenic miRNA dependence in an early neoplastic state...
  6. pmc Role of RhoA-specific guanine exchange factors in regulation of endomitosis in megakaryocytes
    Yuan Gao
    Department of Laboratory Medicine, Yale University, New Haven, CT 06520, USA
    Dev Cell 22:573-84. 2012
    ..These mechanistic insights enhance our understanding of normal versus malignant megakaryocytopoiesis, as well as aberrant mitosis in aneuploid cancers...
  7. pmc Different roles of G protein subunits beta1 and beta2 in neutrophil function revealed by gene expression silencing in primary mouse neutrophils
    Yong Zhang
    Department of Pharmacology, Yale School of Medicine, New Haven, Connecticut 06520, USA
    J Biol Chem 285:24805-14. 2010
    ....