Handan Gunduz-Bruce

Summary

Affiliation: Yale University
Country: USA

Publications

  1. doi request reprint Efficacy of pimozide augmentation for clozapine partial responders with schizophrenia
    Handan Gunduz-Bruce
    Yale School of Medicine, Department of Psychiatry, 300 George Street, New Haven, CT 06510, United States
    Schizophr Res 143:344-7. 2013
  2. pmc Glutamatergic modulation of auditory information processing in the human brain
    Handan Gunduz-Bruce
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
    Biol Psychiatry 71:969-77. 2012
  3. ncbi request reprint Cortisol levels in relation to hippocampal sub-regions in subjects with first episode schizophrenia
    Handan Gunduz-Bruce
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Schizophr Res 94:281-7. 2007
  4. pmc CSF sub-compartments in relation to plasma osmolality in healthy controls and in patients with first episode schizophrenia
    Handan Gunduz-Bruce
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Psychiatry Res 155:57-66. 2007
  5. ncbi request reprint Duration of untreated psychosis and time to treatment response for delusions and hallucinations
    Handan Gunduz-Bruce
    VA Medical Center, Psychiatry Service 118A, 950 Campbell Ave, West Haven, CT 06516, USA
    Am J Psychiatry 162:1966-9. 2005
  6. doi request reprint The acute effects of NMDA antagonism: from the rodent to the human brain
    Handan Gunduz-Bruce
    Yale University School of Medicine, VA Medical Center, Psychiatry Service 116A, West Haven, CT 06516, USA
    Brain Res Rev 60:279-86. 2009
  7. ncbi request reprint Randomized comparison of olanzapine versus risperidone for the treatment of first-episode schizophrenia: 4-month outcomes
    Delbert G Robinson
    Department of Psychiatry, The Zucker Hillside Hospital of the North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Am J Psychiatry 163:2096-102. 2006
  8. doi request reprint Potential psychiatric applications of metabotropic glutamate receptor agonists and antagonists
    John H Krystal
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
    CNS Drugs 24:669-93. 2010
  9. ncbi request reprint Clinical and neuropsychological correlates of white matter abnormalities in recent onset schizophrenia
    Philip R Szeszko
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Neuropsychopharmacology 33:976-84. 2008
  10. pmc Patterns of stress in schizophrenia
    Julia D Betensky
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Psychiatry Res 160:38-46. 2008

Detail Information

Publications17

  1. doi request reprint Efficacy of pimozide augmentation for clozapine partial responders with schizophrenia
    Handan Gunduz-Bruce
    Yale School of Medicine, Department of Psychiatry, 300 George Street, New Haven, CT 06510, United States
    Schizophr Res 143:344-7. 2013
    ....
  2. pmc Glutamatergic modulation of auditory information processing in the human brain
    Handan Gunduz-Bruce
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
    Biol Psychiatry 71:969-77. 2012
    ..On the basis of these findings, we tested whether NAC would reduce ketamine effects on behavior, MMN, and P300 in healthy humans...
  3. ncbi request reprint Cortisol levels in relation to hippocampal sub-regions in subjects with first episode schizophrenia
    Handan Gunduz-Bruce
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Schizophr Res 94:281-7. 2007
    ..Larger scale studies are needed to conclude a link between the two measures, yet it is possible that the negative association that was previously shown in other disorders may not apply to schizophrenia...
  4. pmc CSF sub-compartments in relation to plasma osmolality in healthy controls and in patients with first episode schizophrenia
    Handan Gunduz-Bruce
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Psychiatry Res 155:57-66. 2007
    ..These results suggest that plasma osmolality is related to ventricle size in healthy volunteers and that this physiological link is impaired in patients with first episode schizophrenia...
  5. ncbi request reprint Duration of untreated psychosis and time to treatment response for delusions and hallucinations
    Handan Gunduz-Bruce
    VA Medical Center, Psychiatry Service 118A, 950 Campbell Ave, West Haven, CT 06516, USA
    Am J Psychiatry 162:1966-9. 2005
    ..However, individual psychotic symptoms have not been investigated in this context. The authors examined the relationship between duration of untreated psychosis and time to response for hallucinations and delusions...
  6. doi request reprint The acute effects of NMDA antagonism: from the rodent to the human brain
    Handan Gunduz-Bruce
    Yale University School of Medicine, VA Medical Center, Psychiatry Service 116A, West Haven, CT 06516, USA
    Brain Res Rev 60:279-86. 2009
    ..In the glia, ketamine has significant downstream effects on the glutathione metabolism. Further studies are needed to identify the mechanistic connections between ketamine's effects at the cellular and behavioral levels...
  7. ncbi request reprint Randomized comparison of olanzapine versus risperidone for the treatment of first-episode schizophrenia: 4-month outcomes
    Delbert G Robinson
    Department of Psychiatry, The Zucker Hillside Hospital of the North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Am J Psychiatry 163:2096-102. 2006
    ..The authors compared 4-month treatment outcomes for olanzapine versus risperidone in patients with first-episode schizophrenia spectrum disorders...
  8. doi request reprint Potential psychiatric applications of metabotropic glutamate receptor agonists and antagonists
    John H Krystal
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
    CNS Drugs 24:669-93. 2010
    ..This review also links growing insights into the role of glutamate in the pathophysiology of these disorders to hypothesized mGluR-related treatment mechanisms...
  9. ncbi request reprint Clinical and neuropsychological correlates of white matter abnormalities in recent onset schizophrenia
    Philip R Szeszko
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Neuropsychopharmacology 33:976-84. 2008
    ..These abnormalities have clinical and neuropsychological correlates, which may be useful in further characterizing structure-function relations in schizophrenia and constraining neurobiological models of the disorder...
  10. pmc Patterns of stress in schizophrenia
    Julia D Betensky
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    Psychiatry Res 160:38-46. 2008
    ....
  11. ncbi request reprint Smaller anterior hippocampal formation volume in antipsychotic-naive patients with first-episode schizophrenia
    Philip R Szeszko
    Department of Psychiatry Research, The Zucker Hillside Hospital, 75 59 263rd St, Glen Oaks, NY 11004, USA
    Am J Psychiatry 160:2190-7. 2003
    ..The authors investigated volumetric alterations of the anterior hippocampal formation in patients experiencing a first episode of schizophrenia relative to healthy comparison subjects...
  12. ncbi request reprint DRD2 promoter region variation as a predictor of sustained response to antipsychotic medication in first-episode schizophrenia patients
    Todd Lencz
    Department of Psychiatry Research, The Zucker Hillside Hospital, Glen Oaks, NY 11004, USA
    Am J Psychiatry 163:529-31. 2006
    ....
  13. ncbi request reprint White matter abnormalities in first-episode schizophrenia or schizoaffective disorder: a diffusion tensor imaging study
    Philip R Szeszko
    The Zucker Hillside Hospital, Department of Psychiatry Research, 75 59 263rd St, Glen Oaks, NY 11004, USA
    Am J Psychiatry 162:602-5. 2005
    ..The goal of this study was to investigate brain white matter abnormalities by using diffusion tensor imaging in patients with schizophrenia or schizoaffective disorder close to illness onset...
  14. ncbi request reprint Increased stress and smaller anterior hippocampal volume
    Philip R Szeszko
    Department of Psychiatry Research, The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, New York 11004, USA
    Neuroreport 17:1825-8. 2006
    ..Our results may also have implications for neuropsychiatric disorders that have implicated stress and hippocampal abnormalities in their pathogenesis...
  15. ncbi request reprint Double-blind, placebo-controlled study of modafinil for fatigue and cognition in schizophrenia patients treated with psychotropic medications
    Serge Sevy
    The Zucker Hillside Hospital, North Shore Long Island Jewish Health System, Glen Oaks, NY 11004, USA
    J Clin Psychiatry 66:839-43. 2005
    ..To assess the effects of modafinil on fatigue, symptoms, attention, working memory, and executive functioning in schizophrenia patients treated with psychotropic medications...
  16. ncbi request reprint Mapping cortical thickness and gray matter concentration in first episode schizophrenia
    Katherine L Narr
    Laboratory of Neuro Imaging, Department of Neurology, Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1769, USA
    Cereb Cortex 15:708-19. 2005
    ..Cortical thickness and gray matter concentration mapping produce similar results, although the concentration metric may be influenced by diagnostic differences in extra-cortical cerebrospinal fluid and surface curvature/complexity...
  17. ncbi request reprint Anterior cingulate grey-matter deficits and cannabis use in first-episode schizophrenia
    Philip R Szeszko
    Zucker Hillside Hospital, Psychiatry Research, 75 59 263rd Street, Glen Oaks, NY 11004, USA
    Br J Psychiatry 190:230-6. 2007
    ..Despite the high prevalence of cannabis use in schizophrenia, few studies have examined the potential relationship between cannabis exposure and brain structural abnormalities in schizophrenia...