R V Gueorguieva

Summary

Affiliation: Yale University
Country: USA

Publications

  1. pmc Temporal patterns of adherence to medications and behavioral treatment and their relationship to patient characteristics and treatment response
    Ralitza Gueorguieva
    Department of Biostatistics, Yale University School of Public Health and School of Medicine, New Haven, CT 06520, USA
    Addict Behav 38:2119-27. 2013
  2. pmc Baseline trajectories of heavy drinking and their effects on postrandomization drinking in the COMBINE Study: empirically derived predictors of drinking outcomes during treatment
    Ralitza Gueorguieva
    Yale University School of Public Health, New Haven, CT 06520, USA
    Alcohol 46:121-31. 2012
  3. ncbi request reprint Joint analysis of repeatedly observed continuous and ordinal measures of disease severity
    R V Gueorguieva
    Division of Biostatistics, Department of Epidemiology and Public Health, School of Medicine, Yale University, 60 College St, New Haven, CT 06520, USA
    Stat Med 25:1307-22. 2006
  4. ncbi request reprint Comments about Joint Modeling of Cluster Size and Binary and Continuous Subunit-Specific Outcomes
    Ralitza V Gueorguieva
    Division of Biostatistics, Department of Epidemiology and Public Health, Yale University School of Medicine, 60 College Street, New Haven, Connecticut 06520, USA
    Biometrics 61:862-6; discussion 866-7. 2005
  5. pmc New insights into the efficacy of naltrexone based on trajectory-based reanalyses of two negative clinical trials
    Ralitza Gueorguieva
    Department of Epidemiology, Yale University School of Medicine, New Haven, Connecticut, USA
    Biol Psychiatry 61:1290-5. 2007
  6. pmc Naltrexone and combined behavioral intervention effects on trajectories of drinking in the COMBINE study
    Ralitza Gueorguieva
    Yale University School of Public Health and School of Medicine, New Haven, CT 06520, USA
    Drug Alcohol Depend 107:221-9. 2010
  7. pmc The impact of occupation on self-rated health: cross-sectional and longitudinal evidence from the health and retirement survey
    Ralitza Gueorguieva
    Yale School of Public Health, New Haven, CT 06520 8034, USA
    J Gerontol B Psychol Sci Soc Sci 64:118-24. 2009
  8. ncbi request reprint A risk assessment screening test for very low birth weight
    Ralitza V Gueorguieva
    Department of Epidemiology and Public Health, Yale University, New Haven, Connecticut, USA
    Matern Child Health J 7:127-36. 2003
  9. pmc Trajectories of depression severity in clinical trials of duloxetine: insights into antidepressant and placebo responses
    Ralitza Gueorguieva
    Division of Biostatistics, School of Public Health, Yale University School of Medicine, New Haven, CT 06520 8034, USA
    Arch Gen Psychiatry 68:1227-37. 2011
  10. doi request reprint Length of prenatal participation in WIC and risk of delivering a small for gestational age infant: Florida, 1996-2004
    Ralitza Gueorguieva
    Division of Biostatistics, Department of Epidemiology and Public Health, Yale University, 60 College St, Room 201, New Haven, CT 06520 8034, USA
    Matern Child Health J 13:479-88. 2009

Collaborators

Detail Information

Publications53

  1. pmc Temporal patterns of adherence to medications and behavioral treatment and their relationship to patient characteristics and treatment response
    Ralitza Gueorguieva
    Department of Biostatistics, Yale University School of Public Health and School of Medicine, New Haven, CT 06520, USA
    Addict Behav 38:2119-27. 2013
    ..The results of these analyses may suggest approaches to improving adherence in order to ultimately improve treatment outcome...
  2. pmc Baseline trajectories of heavy drinking and their effects on postrandomization drinking in the COMBINE Study: empirically derived predictors of drinking outcomes during treatment
    Ralitza Gueorguieva
    Yale University School of Public Health, New Haven, CT 06520, USA
    Alcohol 46:121-31. 2012
    ....
  3. ncbi request reprint Joint analysis of repeatedly observed continuous and ordinal measures of disease severity
    R V Gueorguieva
    Division of Biostatistics, Department of Epidemiology and Public Health, School of Medicine, Yale University, 60 College St, New Haven, CT 06520, USA
    Stat Med 25:1307-22. 2006
    ..Data from a depression clinical trial are used for illustration...
  4. ncbi request reprint Comments about Joint Modeling of Cluster Size and Binary and Continuous Subunit-Specific Outcomes
    Ralitza V Gueorguieva
    Division of Biostatistics, Department of Epidemiology and Public Health, Yale University School of Medicine, 60 College Street, New Haven, Connecticut 06520, USA
    Biometrics 61:862-6; discussion 866-7. 2005
    ..The maximum-likelihood approach considered herein is applicable to general situations with multiple clustered or longitudinally measured outcomes of different type and does not require prior specification and extensive programming...
  5. pmc New insights into the efficacy of naltrexone based on trajectory-based reanalyses of two negative clinical trials
    Ralitza Gueorguieva
    Department of Epidemiology, Yale University School of Medicine, New Haven, Connecticut, USA
    Biol Psychiatry 61:1290-5. 2007
    ..The objective of this study was to identify distinct trajectories of daily drinking over time in two negative clinical trials and to determine whether naltrexone affected the probability to follow a particular trajectory...
  6. pmc Naltrexone and combined behavioral intervention effects on trajectories of drinking in the COMBINE study
    Ralitza Gueorguieva
    Yale University School of Public Health and School of Medicine, New Haven, CT 06520, USA
    Drug Alcohol Depend 107:221-9. 2010
    ..It was hypothesized that different treatments may affect different trajectories of drinking...
  7. pmc The impact of occupation on self-rated health: cross-sectional and longitudinal evidence from the health and retirement survey
    Ralitza Gueorguieva
    Yale School of Public Health, New Haven, CT 06520 8034, USA
    J Gerontol B Psychol Sci Soc Sci 64:118-24. 2009
    ..The objective of this study is to estimate occupational differences in self-rated health, both in cross-section and over time, among older individuals...
  8. ncbi request reprint A risk assessment screening test for very low birth weight
    Ralitza V Gueorguieva
    Department of Epidemiology and Public Health, Yale University, New Haven, Connecticut, USA
    Matern Child Health J 7:127-36. 2003
    ..To develop a risk-assessment screening tool for very low birth weight (VLBW) and to compare our empirically derived tool to the nonempirically derived screening tool used by the State of Florida...
  9. pmc Trajectories of depression severity in clinical trials of duloxetine: insights into antidepressant and placebo responses
    Ralitza Gueorguieva
    Division of Biostatistics, School of Public Health, Yale University School of Medicine, New Haven, CT 06520 8034, USA
    Arch Gen Psychiatry 68:1227-37. 2011
    ..The high percentage of failed clinical trials in depression may be due to high placebo response rates and the failure of standard statistical approaches to capture heterogeneity in treatment response...
  10. doi request reprint Length of prenatal participation in WIC and risk of delivering a small for gestational age infant: Florida, 1996-2004
    Ralitza Gueorguieva
    Division of Biostatistics, Department of Epidemiology and Public Health, Yale University, 60 College St, Room 201, New Haven, CT 06520 8034, USA
    Matern Child Health J 13:479-88. 2009
    ..By focusing on small for gestational age, we consider one of the possible pathways through which prenatal nutrition affects fetal growth...
  11. pmc Baseline trajectories of drinking moderate acamprosate and naltrexone effects in the COMBINE study
    Ralitza Gueorguieva
    Yale University School of Public Health and School of Medicine, New Haven, Connecticut, USA
    Alcohol Clin Exp Res 35:523-31. 2011
    ....
  12. ncbi request reprint Absence of significant interactive effects of high-dose D-cycloserine and ethanol in healthy human subjects: preliminary insights into ethanol actions at the glycine B site of NMDA glutamate receptors
    Louis Trevisan
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
    Alcohol Clin Exp Res 32:36-42. 2008
    ....
  13. ncbi request reprint Effect of teenage pregnancy on educational disabilities in kindergarten
    R V Gueorguieva
    Yale University, School of Medicine, New Haven, CT, USA
    Am J Epidemiol 154:212-20. 2001
    ..In contrast to teen age, older maternal age has an adverse effect on a child's educational outcome regardless of whether other factors are controlled for or not...
  14. ncbi request reprint Enhanced sensitivity to the euphoric effects of alcohol in schizophrenia
    DEEPAK C D'SOUZA
    Schizophrenia Biological Research Center, VA Connecticut Healthcare System, West Haven, CT 06516, USA
    Neuropsychopharmacology 31:2767-75. 2006
    ..The absence of 'beneficial' effects of alcohol does not support a self-medication hypothesis of alcohol use in schizophrenia...
  15. ncbi request reprint Estradiol and tryptophan depletion interact to modulate cognition in menopausal women
    Zenab Amin
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06511, USA
    Neuropsychopharmacology 31:2489-97. 2006
    ..These data support the interaction of estrogen and 5-HT in nonreproductive behavior in humans as well as highlight the role of ovarian steroids in cognition...
  16. ncbi request reprint Preliminary evidence of reduced occipital GABA concentrations in puerperal women: a 1H-MRS study
    C Neill Epperson
    Department of Psychiatry, Yale University School of Medicine, and Abraham Ribicoff Research Facilities, Connecticut Mental Health Center, New Haven, CT 06519, USA
    Psychopharmacology (Berl) 186:425-33. 2006
    ..Childbirth is associated with rapid neuroendocrine fluctuations, which are thought to contribute to the phatogenesis of postpartum major depression (PPD)...
  17. ncbi request reprint Opioid receptor gene (OPRM1, OPRK1, and OPRD1) variants and response to naltrexone treatment for alcohol dependence: results from the VA Cooperative Study
    Joel Gelernter
    VA Connecticut Healthcare System, West Haven Campus, West Haven, Connecticut 06516, USA
    Alcohol Clin Exp Res 31:555-63. 2007
    ..A previous report suggested that a functional variant at the genetic locus encoding the mu opioid receptor (Asn40Asp) is such a marker, in short-term (3-month) treatment with the opioid-blocking drug naltrexone (NTX)...
  18. ncbi request reprint Multidimensionality of the Alcohol Withdrawal Symptom Checklist: a factor analysis of the Alcohol Withdrawal Symptom Checklist and CIWA-Ar
    Brian Pittman
    NIAAA Center for the Translational Neuroscience of Alcoholism, Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
    Alcohol Clin Exp Res 31:612-8. 2007
    ....
  19. pmc CSF sub-compartments in relation to plasma osmolality in healthy controls and in patients with first episode schizophrenia
    Handan Gunduz-Bruce
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Psychiatry Res 155:57-66. 2007
    ..These results suggest that plasma osmolality is related to ventricle size in healthy volunteers and that this physiological link is impaired in patients with first episode schizophrenia...
  20. ncbi request reprint Cortisol levels in relation to hippocampal sub-regions in subjects with first episode schizophrenia
    Handan Gunduz-Bruce
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Schizophr Res 94:281-7. 2007
    ..Larger scale studies are needed to conclude a link between the two measures, yet it is possible that the negative association that was previously shown in other disorders may not apply to schizophrenia...
  21. ncbi request reprint Naltrexone is associated with reduced drinking by alcohol dependent patients receiving antidepressants for mood and anxiety symptoms: results from VA Cooperative Study No. 425, "Naltrexone in the treatment of alcoholism"
    John H Krystal
    Alcohol Research Center, VA Connecticut Healthcare System, West Haven, Connecticut 06516, USA
    Alcohol Clin Exp Res 32:85-91. 2008
    ..It is not clear whether naltrexone is effective in reducing alcohol consumption among patients with clinically significant mood symptoms and whether naltrexone favorably interacts with antidepressant medications when they are co-prescribed...
  22. pmc Blunted psychotomimetic and amnestic effects of delta-9-tetrahydrocannabinol in frequent users of cannabis
    DEEPAK CYRIL D'SOUZA
    Schizophrenia Biological Research Center, VA Connecticut Healthcare System, West Haven, CT 06516, USA
    Neuropsychopharmacology 33:2505-16. 2008
    ..These data suggest that frequent users of cannabis are either inherently blunted in their response to, and/or develop tolerance to the psychotomimetic, perceptual altering, amnestic, endocrine, and other effects of cannabinoids...
  23. doi request reprint It is time to take a stand for medical research and against terrorism targeting medical scientists
    John H Krystal
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
    Biol Psychiatry 63:725-7. 2008
  24. pmc Impairment of working memory maintenance and response in schizophrenia: functional magnetic resonance imaging evidence
    Naomi R Driesen
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06519, USA
    Biol Psychiatry 64:1026-34. 2008
    ..This study featured a spatial working memory task, similar to that used in nonhuman primates, that was designed to facilitate separating brain activation into encoding, maintenance, and response phases...
  25. ncbi request reprint Sex, GABA, and nicotine: the impact of smoking on cortical GABA levels across the menstrual cycle as measured with proton magnetic resonance spectroscopy
    C Neill Epperson
    Department of Psychiatry, Yale University School of Medicine, University Towers Suite 2H, 100 York Street, New Haven, CT 06511, USA
    Biol Psychiatry 57:44-8. 2005
    ..Given that nicotine modulates amino acid neurotransmission, we sought to examine the impact of nicotine on cortical gamma-aminobutyric acid (GABA) levels in male and female smokers...
  26. pmc Inter-rater reliability and concurrent validity of DSM-IV opioid dependence in a Hmong isolate using the Thai version of the Semi-Structured Assessment for Drug Dependence and Alcoholism (SSADDA)
    Robert T Malison
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06437, USA
    Addict Behav 36:156-60. 2011
    ..The high concordance between instruments supports the concurrent validity of the diagnosis. Either interview provides reliable, valid OD diagnoses in Thai-speaking Hmong individuals...
  27. ncbi request reprint Gelatin "shots" as a new method for alcohol administration in a laboratory setting
    Elizabeth Ralevski
    Department of Psychiatry, Yale University School of Medicine, VA Connecticut Healthcare System, West Haven, Connecticut, USA
    Alcohol Clin Exp Res 30:473-9. 2006
    ....
  28. ncbi request reprint Potentiation of low dose ketamine effects by naltrexone: potential implications for the pharmacotherapy of alcoholism
    John H Krystal
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06516, USA
    Neuropsychopharmacology 31:1793-800. 2006
    ..However, these data suggest that at levels of NMDA receptor antagonism associated with heavy drinking, this protective effect of naltrexone on drinking is no longer present...
  29. ncbi request reprint Cortical gamma-aminobutyric acid levels across the menstrual cycle in healthy women and those with premenstrual dysphoric disorder: a proton magnetic resonance spectroscopy study
    C Neill Epperson
    Yale Behavioral Gynecology Program, Department of Psychiatry, Yale University School of Medicine University Towers, Suite 2H, 100 York St, New Haven, CT 06511, USA
    Arch Gen Psychiatry 59:851-8. 2002
    ....
  30. ncbi request reprint Preliminary evidence of attenuation of the disruptive effects of the NMDA glutamate receptor antagonist, ketamine, on working memory by pretreatment with the group II metabotropic glutamate receptor agonist, LY354740, in healthy human subjects
    John H Krystal
    Schizophrenia Biological Research Center 116 A, VA Connecticut Healthcare System, West Haven, CT 06516, USA
    Psychopharmacology (Berl) 179:303-9. 2005
    ..Some of the behavioral consequences of deficits in N-methyl-D-aspartate (NMDA) glutamate receptor function are thought to arise from the disinhibition of cortical glutamatergic circuitry...
  31. ncbi request reprint Altered NMDA glutamate receptor antagonist response in individuals with a family vulnerability to alcoholism
    Ismene L Petrakis
    West Haven VA Medical Center 116 A, 950 Campbell Ave, West Haven, CT 06516, USA
    Am J Psychiatry 161:1776-82. 2004
    ....
  32. ncbi request reprint The psychotomimetic effects of intravenous delta-9-tetrahydrocannabinol in healthy individuals: implications for psychosis
    DEEPAK CYRIL D'SOUZA
    Schizophrenia Biological Research Center, VA Connecticut Healthcare System, West Haven, CT 06516, USA
    Neuropsychopharmacology 29:1558-72. 2004
    ..These data warrant further study of whether brain cannabinoid receptor function contributes to the pathophysiology of psychotic disorders...
  33. ncbi request reprint Extracellular metabolites in the cortex and hippocampus of epileptic patients
    Idil Cavus
    Department of Psychiatry, Yale University, New Haven, CT, USA
    Ann Neurol 57:226-35. 2005
    ..Our data suggest that a different neurometabolic process underlies the neocortical epilepsies...
  34. ncbi request reprint Addition of the alpha2-antagonist yohimbine to fluoxetine: effects on rate of antidepressant response
    Gerard Sanacora
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Neuropsychopharmacology 29:1166-71. 2004
    ..The addition of the alpha2-antagonist yohimbine to fluoxetine appears to hasten the antidepressant response. There is also a trend suggesting an increased percentage of responders to the combined treatment at the end of the 6-week trial...
  35. ncbi request reprint Delta-9-tetrahydrocannabinol effects in schizophrenia: implications for cognition, psychosis, and addiction
    DEEPAK CYRIL D'SOUZA
    Schizophrenia Biological Research Center, VA Connecticut Healthcare System, West Haven, CT 06516, USA
    Biol Psychiatry 57:594-608. 2005
    ..Recent advances in the neurobiology of cannabinoids have renewed interest in the association between cannabis and psychotic disorders...
  36. ncbi request reprint Temporoparietal transcranial magnetic stimulation for auditory hallucinations: safety, efficacy and moderators in a fifty patient sample
    Ralph E Hoffman
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06519, USA
    Biol Psychiatry 58:97-104. 2005
    ..Data from the full 50-subject sample incorporating 26 new patients are now presented to more comprehensively assess safety/tolerability, efficacy and moderators of this intervention...
  37. ncbi request reprint Riluzole augmentation in treatment-resistant obsessive-compulsive disorder: an open-label trial
    Vladimir Coric
    Department of Psychiatry, Yale University School of Medicine and Connecticut Mental Health Center, 34 Park Street, New Haven, CT 06519, USA
    Biol Psychiatry 58:424-8. 2005
    ..Recent imaging data suggests glutamatergic dysfunction in the corticostriatal pathway in OCD. We investigated the efficacy of augmentation therapy with riluzole, a glutamate-modulating agent, in treatment-resistant OCD...
  38. ncbi request reprint Baseline and modulated acoustic startle responses in adolescent girls with posttraumatic stress disorder
    Deborah S Lipschitz
    Neuroscience Division, National Center for PTSD, and the Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06824, USA
    J Am Acad Child Adolesc Psychiatry 44:807-14. 2005
    ..To assess baseline and modulated acoustic startle responses in adolescent girls with posttraumatic stress disorder (PTSD)...
  39. ncbi request reprint Cortical gamma-aminobutyric acid levels and the recovery from ethanol dependence: preliminary evidence of modification by cigarette smoking
    Graeme F Mason
    NIAAA Center for the Translational Neuroscience of Alcoholism and Department of Psychiatry, Yale University, School of Medicine, New Haven, CT 06520, USA
    Biol Psychiatry 59:85-93. 2006
    ..This study's objective was to measure time-dependent cortical GABA levels with sobriety in ethanol-dependent patients with mild to moderate withdrawal severity, controlling for alcoholism-related neurotoxicity and smoking...
  40. ncbi request reprint Transcranial magnetic stimulation of left temporoparietal cortex and medication-resistant auditory hallucinations
    Ralph E Hoffman
    Department of Psychiatry, Yale University School of Medicine, Yale New Haven Psychiatric Hospital, 20 York St LV108, New Haven, CT 06504, USA
    Arch Gen Psychiatry 60:49-56. 2003
    ..We sought to determine if a more extended trial of rTMS could significantly reduce AHs that were resistant to antipsychotic medication...
  41. ncbi request reprint Preliminary evidence for medication effects on functional abnormalities in the amygdala and anterior cingulate in bipolar disorder
    Hilary P Blumberg
    Mood Disorders Research Program, Department of Psychiatry, Yale University School of Medicine, 300 George Street, Suite 901, New Haven, CT 06511, USA
    Psychopharmacology (Berl) 183:308-13. 2005
    ..Abnormal amygdala and frontocortical responses to emotional stimuli are implicated in bipolar disorder (BD) and have been proposed as potential treatment targets...
  42. ncbi request reprint Comparative and interactive human psychopharmacologic effects of ketamine and amphetamine: implications for glutamatergic and dopaminergic model psychoses and cognitive function
    John H Krystal
    Department of Psychiatry and Division of Biostatistics, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Conn 06516, USA
    Arch Gen Psychiatry 62:985-94. 2005
    ..Studying the comparative and interactive effects of these agents may provide insights into the roles of the glutamate and monoamine systems in psychosis and cognition...
  43. ncbi request reprint Lack of a therapeutic effect of a 2-week sub-threshold transcranial magnetic stimulation course for treatment-resistant depression
    Nashaat N Boutros
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, USA
    Psychiatry Res 113:245-54. 2002
    ..The duration of the therapeutic effects of rTMS delivered to the left prefrontal cortex using the above-described parameters is highly variable...
  44. ncbi request reprint Cortical gamma-aminobutyric acid type A-benzodiazepine receptors in recovery from alcohol dependence: relationship to features of alcohol dependence and cigarette smoking
    Julie K Staley
    Yale University School of Medicine, 950 Campbell Avenue, New Haven, CT 06516, USA
    Arch Gen Psychiatry 62:877-88. 2005
    ..Adaptations in gamma-aminobutyric acid type A (GABA(A))-benzodiazepine receptors contribute to the neurobiology of human alcohol dependence and withdrawal...
  45. ncbi request reprint Subtype-specific alterations of gamma-aminobutyric acid and glutamate in patients with major depression
    Gerard Sanacora
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Arch Gen Psychiatry 61:705-13. 2004
    ..An initial report, using this technique, suggested that occipital cortex GABA concentrations are reduced in patients with major depressive disorder (MDD) relative to healthy comparison subjects...
  46. ncbi request reprint Absence of behavioral sensitization in healthy human subjects following repeated exposure to ketamine
    Hyun Sang Cho
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Psychopharmacology (Berl) 179:136-43. 2005
    ....
  47. ncbi request reprint Posttraumatic stress disorder and substance use in inner-city adolescent girls
    Deborah S Lipschitz
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06511, USA
    J Nerv Ment Dis 191:714-21. 2003
    ..Inner-city adolescent girls with PTSD exhibit problematic substance use and may be at high risk of developing a comorbid substance-use disorder...
  48. ncbi request reprint Risk factors for cocaine-induced paranoia in cocaine-dependent sibling pairs
    Rasmon Kalayasiri
    Department of Psychiatry, Yale School of Medicine, New Haven, CT 06520, USA
    Drug Alcohol Depend 84:77-84. 2006
    ..Both environmental and genetic factors are thought to play a role, but the specific nature of such contributions is poorly understood...
  49. ncbi request reprint Move over ANOVA: progress in analyzing repeated-measures data and its reflection in papers published in the Archives of General Psychiatry
    Ralitza Gueorguieva
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut, USA
    Arch Gen Psychiatry 61:310-7. 2004
    ..More sophisticated mixed-effects models provide flexibility, and recently developed software makes them available to researchers...
  50. ncbi request reprint Dopamine beta-hydroxylase gene (DbetaH) -1021C-->T influences self-reported paranoia during cocaine self-administration
    Rasmon Kalayasiri
    Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut 06519, USA
    Biol Psychiatry 61:1310-3. 2007
    ..Variation in the gene for dopamine beta-hydroxylase (DbetaH) has been reported to associate with cocaine-induced paranoia as assessed by retrospective self-report. This association has yet to be tested prospectively...
  51. ncbi request reprint A paradigm to investigate the self-regulation of cocaine administration in humans
    Atapol Sughondhabirom
    Department of Psychiatry, Yale University, New Haven, CT 06519, USA
    Psychopharmacology (Berl) 180:436-46. 2005
    ..The current study assessed the feasibility, safety, and validity of a model of ad libitum cocaine self-administration, in which participants self-selected the timing of cocaine infusions, using PCA techniques...
  52. ncbi request reprint Self-reported paranoia during laboratory "binge" cocaine self-administration in humans
    Rasmon Kalayasiri
    Department of Psychiatry, Yale School of Medicine, 34 Park Street, New Haven, CT 06519, USA
    Pharmacol Biochem Behav 83:249-56. 2006
    ..Such methods may facilitate our understanding of the vulnerability to CIP in humans...
  53. ncbi request reprint Control group bias in randomized atypical antipsychotic medication trials for schizophrenia
    Scott W Woods
    Treatment Research Program, Department of Psychiatry and Biostatistics Division, Yale University School of Medicine, New Haven, Conn 06519, USA
    Arch Gen Psychiatry 62:961-70. 2005
    ..This strategy requires an assumption of constancy, that the novel medication will perform the same way in a study with only active controls as it would have in a placebo-controlled trial...