Cary P Gross

Summary

Affiliation: Yale University
Country: USA

Publications

  1. pmc Predictors of venous thromboembolism in patients with advanced common solid cancers
    Isaac E Hall
    Sections of General Internal Medicine, Primary Care Center, Yale University School of Medicine, 333 Cedar Street, P O Box 208025, New Haven, CT 06520, USA
    J Cancer Epidemiol 2009:182521. 2009
  2. pmc Risk prediction model for heart failure and cardiomyopathy after adjuvant trastuzumab therapy for breast cancer
    Ghideon Ezaz
    Department of Internal Medicine, Section of General Internal Medicine, Yale School of Medicine, New Haven, CT
    J Am Heart Assoc 3:e000472. 2014
  3. pmc The cost of breast cancer screening in the Medicare population
    Cary P Gross
    Cancer Outcomes, Public Policy, and Effectiveness Research COPPER Center, Yale Comprehensive Cancer Center and Yale University School of Medicine, New Haven, CT 06520, USA
    JAMA Intern Med 173:220-6. 2013
  4. doi request reprint Mohs micrographic surgery and surgical excision for nonmelanoma skin cancer treatment in the Medicare population
    Kate V Viola
    Department of Dermatology, Albert Einstein College of Medicine, Bronx, New York, USA
    Arch Dermatol 148:473-7. 2012
  5. ncbi request reprint Cancer trial enrollment after state-mandated reimbursement
    C P Gross
    Sections of General Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA
    J Natl Cancer Inst 96:1063-9. 2004
  6. ncbi request reprint Relation between Medicare screening reimbursement and stage at diagnosis for older patients with colon cancer
    Cary P Gross
    Section of General Internal Medicine, Department of Medicine, Robert Wood Johnson Clinical Scholars Program, Yale University School of Medicine, Primary Care Center, New Haven, Conn 06520, USA
    JAMA 296:2815-22. 2006
  7. ncbi request reprint The generalizability of observational data to elderly patients was dependent on the research question in a systematic review
    Cary P Gross
    Section of General Internal Medicine, Department of Medicine, Yale New Haven Hospital Center for Outcomes Research and Evaluation, 20 York St, New Haven, CT 06504, USA
    J Clin Epidemiol 58:130-7. 2005
  8. ncbi request reprint Enrollment of older persons in cancer trials after the medicare reimbursement policy change
    Cary P Gross
    Section of General Internal Medicine, Robert Wood Johnson Clinical Scholars Program, Yale University School of Medicine, Primary Care Center, New Haven, Connecticut 06520, USA
    Arch Intern Med 165:1514-20. 2005
  9. ncbi request reprint Enrolling older persons in cancer trials: the effect of sociodemographic, protocol, and recruitment center characteristics
    Cary P Gross
    Section of General Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA
    J Clin Oncol 23:4755-63. 2005
  10. pmc The impact of venous thromboembolism on risk of death or hemorrhage in older cancer patients
    Cary P Gross
    Section of General Internal Medicine, Yale University School of Medicine, New Haven, CT, USA
    J Gen Intern Med 22:321-6. 2007

Detail Information

Publications107 found, 100 shown here

  1. pmc Predictors of venous thromboembolism in patients with advanced common solid cancers
    Isaac E Hall
    Sections of General Internal Medicine, Primary Care Center, Yale University School of Medicine, 333 Cedar Street, P O Box 208025, New Haven, CT 06520, USA
    J Cancer Epidemiol 2009:182521. 2009
    ..4 VTEs/100 patient-years). In a high-risk population with advanced cancer, substantial variability in VTE risk exists, with notable differences according to cancer type and stage...
  2. pmc Risk prediction model for heart failure and cardiomyopathy after adjuvant trastuzumab therapy for breast cancer
    Ghideon Ezaz
    Department of Internal Medicine, Section of General Internal Medicine, Yale School of Medicine, New Haven, CT
    J Am Heart Assoc 3:e000472. 2014
    ..We sought to develop a clinical risk score that identifies older women with breast cancer who are at higher risk of HF or CM after trastuzumab...
  3. pmc The cost of breast cancer screening in the Medicare population
    Cary P Gross
    Cancer Outcomes, Public Policy, and Effectiveness Research COPPER Center, Yale Comprehensive Cancer Center and Yale University School of Medicine, New Haven, CT 06520, USA
    JAMA Intern Med 173:220-6. 2013
    ....
  4. doi request reprint Mohs micrographic surgery and surgical excision for nonmelanoma skin cancer treatment in the Medicare population
    Kate V Viola
    Department of Dermatology, Albert Einstein College of Medicine, Bronx, New York, USA
    Arch Dermatol 148:473-7. 2012
    ..To identify Medicare use rates of Mohs micrographic surgery (MMS) and surgical excision for the treatment of nonmelanoma skin cancer (NMSC) and to identify patient, lesion, and geographic characteristics associated with treatment type...
  5. ncbi request reprint Cancer trial enrollment after state-mandated reimbursement
    C P Gross
    Sections of General Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA
    J Natl Cancer Inst 96:1063-9. 2004
    ..We examined whether state policies that ensure coverage of routine medical care costs for cancer trial participants are associated with an increase in clinical trial enrollment...
  6. ncbi request reprint Relation between Medicare screening reimbursement and stage at diagnosis for older patients with colon cancer
    Cary P Gross
    Section of General Internal Medicine, Department of Medicine, Robert Wood Johnson Clinical Scholars Program, Yale University School of Medicine, Primary Care Center, New Haven, Conn 06520, USA
    JAMA 296:2815-22. 2006
    ..Medicare's reimbursement policy was changed in 1998 to provide coverage for screening colonoscopies for patients with increased colon cancer risk, and expanded further in 2001 to cover screening colonoscopies for all individuals...
  7. ncbi request reprint The generalizability of observational data to elderly patients was dependent on the research question in a systematic review
    Cary P Gross
    Section of General Internal Medicine, Department of Medicine, Yale New Haven Hospital Center for Outcomes Research and Evaluation, 20 York St, New Haven, CT 06504, USA
    J Clin Epidemiol 58:130-7. 2005
    ....
  8. ncbi request reprint Enrollment of older persons in cancer trials after the medicare reimbursement policy change
    Cary P Gross
    Section of General Internal Medicine, Robert Wood Johnson Clinical Scholars Program, Yale University School of Medicine, Primary Care Center, New Haven, Connecticut 06520, USA
    Arch Intern Med 165:1514-20. 2005
    ..This study evaluates the impact of the Medicare reimbursement policy change on enrollment of older patients into cancer trials...
  9. ncbi request reprint Enrolling older persons in cancer trials: the effect of sociodemographic, protocol, and recruitment center characteristics
    Cary P Gross
    Section of General Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA
    J Clin Oncol 23:4755-63. 2005
    ..To determine the effect of patient, protocol, geographic, and institutional factors on enrollment of older persons onto cancer trials...
  10. pmc The impact of venous thromboembolism on risk of death or hemorrhage in older cancer patients
    Cary P Gross
    Section of General Internal Medicine, Yale University School of Medicine, New Haven, CT, USA
    J Gen Intern Med 22:321-6. 2007
    ..Among older cancer patients, there is uncertainty about the degree to which venous thromboembolism (VTE) and its treatment increase the risk of death or major hemorrhage...
  11. pmc Assessing the impact of screening colonoscopy on mortality in the medicare population
    Cary P Gross
    Yale School of Medicine, Section of General Internal Medicine, New Haven, CT 06520, USA
    J Gen Intern Med 26:1441-9. 2011
    ..We estimated the expected benefits (decreased mortality from CRC) and harms (SC-related mortality) of SC based on sex, age, and comorbidity...
  12. pmc Does random treatment assignment cause harm to research participants?
    Cary P Gross
    Section of General Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA
    PLoS Med 3:e188. 2006
    ..We therefore performed a systematic review to quantify the differences in health outcomes between randomized trial participants and eligible non-participants...
  13. ncbi request reprint Multimorbidity and survival in older persons with colorectal cancer
    Cary P Gross
    General Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Am Geriatr Soc 54:1898-904. 2006
    ..To ascertain the effect of common chronic conditions on mortality in older persons with colorectal cancer...
  14. ncbi request reprint The effect of age and chronic illness on life expectancy after a diagnosis of colorectal cancer: implications for screening
    Cary P Gross
    Robert Wood Johnson Clinical Scholars Program and Primary Care Center, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Ann Intern Med 145:646-53. 2006
    ..Older adults with shorter life expectancies may receive less benefit from colorectal cancer screening than younger, healthier patients...
  15. ncbi request reprint Factors influencing physicians' reported use of anticoagulation therapy in nonvalvular atrial fibrillation: a cross-sectional survey
    Cary P Gross
    Section of General Medicine, Yale University School of Medicine, New Haven, Connecticut 06511, USA
    Clin Ther 25:1750-64. 2003
    ..Some elderly patients with nonvalvular atrial fibrillation (NVAF) who might benefit from warfarin therapy do not receive it...
  16. pmc Racial disparities in cancer therapy: did the gap narrow between 1992 and 2002?
    Cary P Gross
    Section of General Internal Medicine, Robert Wood Johnson Clinical Scholars Program, Yale Cancer Center, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Cancer 112:900-8. 2008
    ..The purpose of this study was to determine whether racial disparities in cancer therapy had diminished since the time they were initially documented in the early 1990s...
  17. pmc Disclosure of financial competing interests in randomised controlled trials: cross sectional review
    Cary P Gross
    Section of General Internal Medicine, Department of Medicine, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA
    BMJ 326:526-7. 2003
  18. ncbi request reprint Impact of managed care on cancer trial enrollment
    C P Gross
    Sections of General Internal Medicine, Yale University School of Medicine, Primary Care Center, 333 Cedar St, PO Box 208025, New Haven, CT 06520, USA
    J Clin Oncol 23:3811-8. 2005
    ..To determine the relationship between managed care market activity and cancer trial enrollment...
  19. ncbi request reprint Relation between prepublication release of clinical trial results and the practice of carotid endarterectomy
    C P Gross
    Primary Care Section, Yale University School of Medicine, New Haven, Conn 06520, USA
    JAMA 284:2886-93. 2000
    ..Little is known about how clinical practice is affected by disseminating results of clinical trials prior to publication in peer-reviewed journals...
  20. ncbi request reprint Reporting the recruitment process in clinical trials: who are these patients and how did they get there?
    Cary P Gross
    Yale University School of Medicine, Yale New Haven Hospital Center for Outcomes Research and Evaluation, PO Box 208025, 333 Cedar Street, New Haven, Connecticut 06520, USA
    Ann Intern Med 137:10-6. 2002
    ..The recruitment process reported in published RCTs has not been systematically evaluated...
  21. pmc State expenditures for tobacco-control programs and the tobacco settlement
    Cary P Gross
    Department of Medicine, Yale University School of Medicine, Primary Care Center, New Haven, Conn 06520, USA
    N Engl J Med 347:1080-6. 2002
    ..Despite controversy surrounding the use of funds arising from settlement agreements with the tobacco industry, little is known about the role of these funds in expenditures for state tobacco-control programs...
  22. ncbi request reprint Resident expectations of morning report: a multi-institutional study
    C P Gross
    Department of Internal Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Arch Intern Med 159:1910-4. 1999
    ..Morning report, a cornerstone of inter nal medicine residency programs for many years, involves a diverse group of teachers and learners with heterogeneous learning goals...
  23. pmc Characteristics associated with the use of nonanatomic resections among Medicare patients undergoing resections of early-stage lung cancer
    Anthony W Kim
    Section of Thoracic Surgery, Department of Therapeutic Radiology and Radiation Oncology, Cancer Outcomes, Public Policy, and Effectiveness Research COPPER Center, Yale Comprehensive Cancer Center, Yale School of Medicine, Yale University, New Haven, Connecticut 06520, USA
    Ann Thorac Surg 94:895-901. 2012
    ..However it is unclear how race, clinical, and hospital characteristics affect the surgical approach among patients undergoing resection...
  24. pmc Use of new treatment modalities for non-small cell lung cancer care in the Medicare population
    Michael T Vest
    Department of Internal Medicine, Section of Pulmonary and Critical Care Medicine, Yale School of Medicine, New Haven, CT 06520, USA
    Chest 143:429-35. 2013
    ..The adoption of these techniques and their impact on access to cancer care among Medicare beneficiaries with stage I NSCLC are unknown...
  25. pmc Trends and clinical implications of preoperative breast MRI in Medicare beneficiaries with breast cancer
    Brigid K Killelea
    Department of Surgery, Yale University School of Medicine, New Haven, CT, USA
    Breast Cancer Res Treat 141:155-63. 2013
    ..In conclusion, the use of preoperative breast MRI has increased substantially among older women with breast cancer and is associated with an increased likelihood of being diagnosed with bilateral cancer, and more invasive surgery...
  26. ncbi request reprint Effectiveness of radiation therapy in older women with ductal carcinoma in situ
    Benjamin D Smith
    Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA
    J Natl Cancer Inst 98:1302-10. 2006
    ..In a cohort of older women with DCIS, we sought to determine whether radiation therapy was associated with a clinically significant benefit...
  27. pmc The cost implications of prostate cancer screening in the Medicare population
    Xiaomei Ma
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut Cancer Outcomes, Public Policy and Effectiveness Research Center, Yale University, New Haven, Connecticut
    Cancer 120:96-102. 2014
    ..Recent debate about prostate-specific antigen (PSA)-based testing for prostate cancer screening among older men has rarely considered the cost of screening...
  28. doi request reprint Age-based and sex-based disparities in screening colonoscopy use among medicare beneficiaries
    John Gancayco
    Digestive Diseases, Yale School of Medicine, Yale Comprehensive Cancer Center, New Haven, CT, USA
    J Clin Gastroenterol 47:630-6. 2013
    ..We assessed the relation between sex, age, and receipt of screening colonoscopy overall and within strata of life expectancy...
  29. pmc Assessing the impact of a cooperative group trial on breast cancer care in the medicare population
    Pamela R Soulos
    Yale School of Medicine, Primary Care Center, New Haven, CT 06520, USA
    J Clin Oncol 30:1601-7. 2012
    ..Although treatment guidelines were changed to indicate that some women could forego RT, the impact of the C9343 results on clinical practice is unclear...
  30. pmc The adoption of new adjuvant radiation therapy modalities among Medicare beneficiaries with breast cancer: clinical correlates and cost implications
    Kenneth B Roberts
    Cancer Outcomes, Public Policy, and Effectiveness Research COPPER Center, Yale Comprehensive Cancer Center and Yale University School of Medicine, New Haven, Connecticut, USA
    Int J Radiat Oncol Biol Phys 85:1186-92. 2013
    ..New radiation therapy modalities have broadened treatment options for older women with breast cancer, but it is unclear how clinical factors, geographic region, and physician preference affect the choice of radiation therapy modality...
  31. doi request reprint Patterns of care and outcomes associated with intensity-modulated radiation therapy versus conventional radiation therapy for older patients with head-and-neck cancer
    James B Yu
    Department of Therapeutic Radiology, Yale School of Medicine, New Haven, CT, USA
    Int J Radiat Oncol Biol Phys 83:e101-7. 2012
    ..We performed a retrospective cohort study of Medicare patients treated with IMRT compared with standard RT to assess outcomes in national practice...
  32. pmc Thoroughness of mediastinal staging in stage IIIA non-small cell lung cancer
    Michael T Vest
    Department of Internal Medicine, Section of Pulmonary and Critical Care Medicine, Yale Comprehensive Cancer Center, New Haven, Connecticut, USA
    J Thorac Oncol 7:188-95. 2012
    ..Studies have suggested that invasive mediastinal staging is underutilized, although practice patterns have not been rigorously evaluated...
  33. ncbi request reprint The impact of socioeconomic status and race on trial participation for older women with breast cancer
    Cary P Gross
    Section of General Internal Medicine, Department of Medicine, Robert Wood Johnson Clinical Scholars Program, New Haven, Connecticut, USA
    Cancer 103:483-91. 2005
    ..Although socioeconomic status (SES) is associated with both race and age, to the authors' knowledge little is known regarding the impact of SES on trial enrollment among older women with breast cancer...
  34. pmc Variation in receipt of radiation therapy after breast-conserving surgery: assessing the impact of physicians and geographic regions
    Aaron J Feinstein
    Cancer Outcomes, Public Policy, and Effectiveness Research COPPER Center, Yale Comprehensive Cancer Center, New Haven, CT, USA
    Med Care 51:330-8. 2013
    ..Little is known about the impact of physicians and regional factors on the use of RT across LE groups...
  35. ncbi request reprint Effectiveness of radiation therapy for older women with early breast cancer
    Benjamin D Smith
    Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06520 8040, USA
    J Natl Cancer Inst 98:681-90. 2006
    ..Recent clinical trials have questioned the necessity of breast radiation therapy for older women with early breast cancer. However, the effectiveness of radiation therapy for older women in the community setting has not been addressed...
  36. pmc Effect of β-blockers on cardiac and pulmonary events and death in older adults with cardiovascular disease and chronic obstructive pulmonary disease
    David S H Lee
    Department of Pharmacy Practice, College of Pharmacy, Oregon State University Oregon Health and Science University, Portland, OR Department of Medicine, Yale School of Medicine Yale School of Public Health, New Haven, CT
    Med Care 52:S45-51. 2014
    ..Furthermore, medications given for one condition may adversely affect other outcomes. β-Blocker use with coexisting cardiovascular disease (CVD) and chronic obstructive pulmonary disease (COPD) is such a situation...
  37. ncbi request reprint The impact of chronic illnesses on the use and effectiveness of adjuvant chemotherapy for colon cancer
    Cary P Gross
    Section of General Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Cancer 109:2410-9. 2007
    ..It is unclear how noncancer conditions affect the use or effectiveness of adjuvant therapy among older patients with colon cancer...
  38. pmc A method for partitioning the attributable fraction of multiple time-dependent coexisting risk factors for an adverse health outcome
    Haiqun Lin
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, USA
    Am J Public Health 103:177-82. 2013
    ..We decomposed the total effect of coexisting diseases on a timed occurrence of an adverse outcome into additive effects from individual diseases...
  39. pmc Multilevel interventions: study design and analysis issues
    Paul D Cleary
    Yale School of Public Health, 60 College St, LEPH 210, PO Box 208034, New Haven, CT 06520 8034, USA
    J Natl Cancer Inst Monogr 2012:49-55. 2012
    ..This chapter reviews designs for assessing multilevel interventions and analytic ways of controlling for potentially confounding variables that can account for the complex structure of multilevel data...
  40. doi request reprint Nondermatologists' use of predictive terms for a potentially malignant lesion
    Whitney L Tolpinrud
    Yale University School of Medicine, New Haven, CT, USA
    South Med J 104:477-81. 2011
    ..Skin cancer is frequently suspected by nondermatologists. Many dermatology practices currently do not triage referrals from nondermatologists. Little is known how nondermatologists describe lesions of concern when making referrals...
  41. ncbi request reprint Postmastectomy radiation and survival in older women with breast cancer
    Benjamin D Smith
    Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA
    J Clin Oncol 24:4901-7. 2006
    ..As recent evidence suggests that certain adjuvant treatments appropriate for younger women may only be marginally beneficial for older women, we sought to determine whether PMRT improves survival for older women with breast cancer...
  42. ncbi request reprint Perceptions of Active Surveillance and Treatment Recommendations for Low-risk Prostate Cancer: Results from a National Survey of Radiation Oncologists and Urologists
    Simon P Kim
    Departments of Urology Internal Medicine, Cancer Outcomes, Public Policy and Effectiveness Research COPPER Center Yale University, New Haven, CT Department of Radiation Oncology, Harvard Medical School, Brigham and Women s Hospital, Boston, MA Department of Surgery, Fox Chase Cancer Center Temple University Health System, Philadelphia, PA Division of Health Care Policy and Research, Knowledge and Evaluation Research Unit Department of Urology, Mayo Clinic, Rochester Division of Health Care Policy and Research, Mayo Clinic, Rochester, MN Department of Radiation Oncology, Cancer Outcomes, Public Policy, and Effectiveness Research Center COPPER, Yale University, New Haven, CT Division of Urology, Harvard Medical School, Brigham and Women s Hospital, Boston, MA HealthPartners Institute for Education and Research, Minneapolis, MN Cancer Prognostics and Health Outcomes, University of Montreal Health Center, Montreal, QC, Canada Bioethics Research Unit, Knowledge and Evaluation Research Unit, Division of General Medicine, Mayo Clinic, Rochester, MN
    Med Care 52:579-85. 2014
    ..With the growing concerns about overtreatment in prostate cancer, the extent to which radiation oncologists and urologists perceive active surveillance (AS) as effective and recommend it to patients are unknown...
  43. ncbi request reprint Antihypertensive medications and serious fall injuries in a nationally representative sample of older adults
    Mary E Tinetti
    Section of Geriatrics, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut2Yale School of Public Health, New Haven, Connecticut
    JAMA Intern Med 174:588-95. 2014
    ..The potential harms vs benefits of antihypertensive medications should be weighed in deciding to continue treatment with antihypertensive medications in older adults with multiple chronic conditions. ..
  44. pmc For-profit hospital ownership status and use of brachytherapy after breast-conserving surgery
    Sounok Sen
    Cancer Outcomes, Public Policy and Effectiveness Research COPPER Center, Yale Cancer Center and Yale University School of Medicine, New Haven, CT
    Surgery 155:776-88. 2014
    ..Among Medicare beneficiaries, we examined whether hospital ownership status is associated with the use of breast brachytherapy-a newer and more expensive modality-as well as overall RT...
  45. doi request reprint Incidence of heart failure or cardiomyopathy after adjuvant trastuzumab therapy for breast cancer
    Jersey Chen
    Section of Cardiovascular Medicine, Department of Medicine, Yale University School of Medicine, New Haven, CT 06520, USA
    J Am Coll Cardiol 60:2504-12. 2012
    ..The purpose of this study was to estimate heart failure (HF) and cardiomyopathy (CM) rates after adjuvant trastuzumab therapy and chemotherapy in a population of older women with early-stage breast cancer...
  46. pmc Patterns of use and short-term complications of breast brachytherapy in the national medicare population from 2008-2009
    Carolyn J Presley
    Yale University School of Medicine, New Haven, CT 06520, USA
    J Clin Oncol 30:4302-7. 2012
    ..Brachytherapy has disseminated into clinical practice as an alternative to whole-breast irradiation (WBI) for early-stage breast cancer; however, current national treatment patterns and associated complications remain unknown...
  47. pmc Proton versus intensity-modulated radiotherapy for prostate cancer: patterns of care and early toxicity
    James B Yu
    Yale University School of Medicine, Department of Therapeutic Radiology, 40 Park St, New Haven, CT 06511, USA
    J Natl Cancer Inst 105:25-32. 2013
    ..We therefore compared patterns of PRT use, cost, and early toxicity among Medicare beneficiaries with prostate cancer with those of intensity-modulated radiotherapy (IMRT)...
  48. ncbi request reprint The population level prevalence and correlates of appropriate and inappropriate imaging to stage incident prostate cancer in the medicare population
    Danil V Makarov
    Robert Wood Johnson Clinical Scholars Program, Yale University School of Medicine, New Haven, United States
    J Urol 187:97-102. 2012
    ..According to guidelines most men with incident prostate cancer do not require staging imaging. We determined the population level prevalence and correlates of appropriate and inappropriate imaging in this cohort...
  49. ncbi request reprint Participation in cancer clinical trials: race-, sex-, and age-based disparities
    Vivek H Murthy
    Section of General Internal Medicine, Department of Medicine, Yale University School of Medicine, New Haven, Conn 06520, USA
    JAMA 291:2720-6. 2004
    ..Despite the importance of diversity of cancer trial participants with regard to race, ethnicity, age, and sex, there is little recent information about the representation of these groups in clinical trials...
  50. pmc Anti-hypertensive medications and cardiovascular events in older adults with multiple chronic conditions
    Mary E Tinetti
    Department of Medicine, Yale School of Medicine, New Haven, Connecticut, United States of America Yale School of Public Health, New Haven, Connecticut, United States of America
    PLoS ONE 9:e90733. 2014
    ..Whether these results generalize to all older adults, most of whom have multiple chronic conditions, is uncertain...
  51. doi request reprint Associations between mental health and surgical outcomes among women undergoing mastectomy for cancer
    Justin P Fox
    Robert Wood Johnson Foundation Clinical Scholars Program, Yale School of Medicine, New Haven, CT, USA
    Breast J 19:276-84. 2013
    ..Greater efforts are needed to identify and manage these patients with psychiatric and substance use disorders during the perioperative period...
  52. ncbi request reprint A randomized outpatient trial of a decision-support information technology tool
    Michael Apkon
    Yale New Haven Health, Yale University School of Medicine, New Haven, Conn, USA
    Arch Intern Med 165:2388-94. 2005
    ..Congress mandated the evaluation of Problem-Knowledge Couplers (PKC Corp, Burlington, Vt), a decision-support tool proposed for the Department of Defense's new health information network...
  53. pmc The impact of hypomethylating agents on the cost of care and survival of elderly patients with myelodysplastic syndromes
    Rong Wang
    School of Medicine, Yale University, New Haven, CT, United States
    Leuk Res 36:1370-5. 2012
    ..The magnitude of the cost of care underscores a need for comparative cost-effectiveness studies to reduce the clinical and economic burden of MDS...
  54. pmc Contribution of individual diseases to death in older adults with multiple diseases
    Mary E Tinetti
    Department of Internal Medicine, School of Medicine, New Haven, Connecticut 06520, USA
    J Am Geriatr Soc 60:1448-56. 2012
    ..To determine empirically the diseases contributing most commonly and strongly to death in older adults, accounting for coexisting diseases...
  55. doi request reprint The association between diffusion of the surgical robot and radical prostatectomy rates
    Danil V Makarov
    Robert Wood Johnson Foundation Clinical Scholars Program, Yale University School of Medicine, New Haven, CT, USA
    Med Care 49:333-9. 2011
    ..Despite its expense and controversy surrounding its benefit, the surgical robot has been widely adopted for the treatment of prostate cancer...
  56. doi request reprint Renal ultrasonography in the evaluation of acute kidney injury: developing a risk stratification framework
    Adam Licurse
    Yale University, New Haven, CT 06520 8025, USA
    Arch Intern Med 170:1900-7. 2010
    ..In adult inpatients with acute kidney injury (AKI), clinicians routinely order a renal ultrasonography (RUS) study. It is unclear how often this test provides clinically useful information...
  57. pmc Pattern of hypomethylating agents use among elderly patients with myelodysplastic syndromes
    Rong Wang
    Department of Epidemiology and Public Health, Yale School of Medicine, New Haven, CT 06520 8034, USA
    Leuk Res 35:904-8. 2011
    ..Relatively few MDS patients were treated with HMAs during the introduction period of these agents, and multiple patient characteristics such as sex, comorbidities, and MDS subtype influence the likelihood a patient receives HMAs...
  58. ncbi request reprint Is there evidence of implicit exclusion criteria for elderly subjects in randomized trials? Evidence from the GUSTO-1 study
    Harlan M Krumholz
    Section of Cardiovascular Medicine, Department of Medicine, Yale University School of Medicine, New Haven, Conn 06520 8088, USA
    Am Heart J 146:839-47. 2003
    ....
  59. pmc Comorbidities and survival in a large cohort of patients with newly diagnosed myelodysplastic syndromes
    Rong Wang
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, United States
    Leuk Res 33:1594-8. 2009
    ..This study confirms comorbidity as a significant and independent determinant of MDS survival, and the findings underscore the importance to take comorbid conditions into account when assessing the prognosis of MDS...
  60. ncbi request reprint Cardiovascular events, early discontinuation of trastuzumab, and their impact on survival
    Shi Yi Wang
    Department of Chronic Disease Epidemiology, Yale School of Public Health, 60 College Street, P O Box 208034, New Haven, CT, 06520, USA
    Breast Cancer Res Treat 146:411-9. 2014
    ....
  61. pmc CA125 level association with chemotherapy toxicity and functional status in older women with ovarian cancer
    Elizabeth Won
    Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Int J Gynecol Cancer 23:1022-8. 2013
    ..CA125 is a sensitive biomarker for tumor burden. The study evaluates the association between CA125, geriatric assessment (GA), and treatment toxicity...
  62. pmc Hospital-level outcomes associated with laparoscopic colectomy for cancer in the minimally invasive era
    Justin P Fox
    Robert Wood Johnson Clinical Scholars Program, Department of Medicine, Yale School of Medicine, 333 Cedar Street, SHM 1E 61, PO Box 208088, New Haven, CT 06520 8088, USA
    J Gastrointest Surg 16:2112-9. 2012
    ..With broader adoption of laparoscopic colectomy for cancer in the USA, it is unclear if laparoscopic colectomy continues to be associated with shorter hospitalization and comparable morbidity...
  63. doi request reprint Immortal time bias: a frequently unrecognized threat to validity in the evaluation of postoperative radiotherapy
    Henry S Park
    Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA
    Int J Radiat Oncol Biol Phys 83:1365-73. 2012
    ..To evaluate the influence of immortal time bias on observational cohort studies of postoperative radiotherapy (PORT) and the effectiveness of sequential landmark analysis to account for this bias...
  64. doi request reprint Geographic analysis of the radiation oncology workforce
    Sanjay Aneja
    Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA
    Int J Radiat Oncol Biol Phys 82:1723-9. 2012
    ..To evaluate trends in the geographic distribution of the radiation oncology (RO) workforce...
  65. pmc Promoting transparency in pharmaceutical industry-sponsored research
    Joseph S Ross
    Section of General Internal Medicine, Yale University School of Medicine and Center for Outcomes Research and Evaluation, Yale New Haven Hospital, New Haven, CT 06520 8093, USA
    Am J Public Health 102:72-80. 2012
    ..Minimizing marketing's impact on clinical trial research and strengthening the science will protect medical literature's integrity and the public's health...
  66. ncbi request reprint Geographical information systems: applications and limitations in oncology research
    Sanjay Aneja
    Yale School of Medicine, New Haven, Connecticut, USA
    Oncology (Williston Park) 25:1221-5. 2011
    ..Our aims are to help clinicians and policy makers interpret studies generated using GIS, and to help clinical investigators implement GIS in future research...
  67. ncbi request reprint Adoption of spironolactone therapy for older patients with heart failure and left ventricular systolic dysfunction in the United States, 1998-2001
    Frederick A Masoudi
    Division of Cardiology, Department of Medicine, Denver Health Medical Center, Denver, CO 80204, USA
    Circulation 112:39-47. 2005
    ..We studied the adoption of spironolactone therapy after publication of the Randomized Aldactone Evaluation Study (RALES) in national cohorts of older patients hospitalized for heart failure...
  68. pmc Examining the cost-effectiveness of radiation therapy among older women with favorable-risk breast cancer
    Sounok Sen
    Affiliations of authors Cancer Outcomes, Public Policy and Effectiveness Research COPPER Center, Yale Cancer Center SS, S YW, PRS, JBL, kbr, JBY, SBE, ABC, CPG, Department of Epidemiology and Public Health S YW, Section of General Internal Medicine, Department of Internal Medicine PRS, JBL, CPG, Department of Therapeutic Radiology KBR, JBY, SBE, and Department of Surgery ABC, Yale University School of Medicine, New Haven, CT Department of Health Policy and Management, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD KDF
    J Natl Cancer Inst 106:dju008. 2014
    ....
  69. doi request reprint Mortality from nonneoplastic skin disease in the United States
    Jason P Lott
    Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut Robert Wood Johnson Foundation Clinical Scholars Program, Yale University School of Medicine, New Haven, Connecticut Veterans Administration VA Connecticut Healthcare System, New Haven, Connecticut Electronic address
    J Am Acad Dermatol 70:47-54.e1. 2014
    ..The mortality burden from nonneoplastic skin disease in the United States is unknown...
  70. ncbi request reprint Quality of cancer survivorship care in the military health system (TRICARE)
    Justin P Fox
    Robert Wood Johnson Foundation Clinical Scholars Program, Yale School of Medicine, New Haven, CT, USA
    Cancer J 19:1-9. 2013
    ..We conducted this study to determine how frequently breast, prostate, and colorectal cancer survivors received recommended follow-up care and HCI tests during the survivorship period...
  71. ncbi request reprint Screening colonoscopy use among individuals at higher colorectal cancer risk
    Anna V Longacre
    Section of Digestive Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA
    J Clin Gastroenterol 40:490-6. 2006
    ..To describe screening colonoscopy use in those with a family history of colorectal cancer (CRC)...
  72. ncbi request reprint Validity of a simple ST-elevation acute myocardial infarction risk index: are randomized trial prognostic estimates generalizable to elderly patients?
    Saif S Rathore
    Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn, USA
    Circulation 107:811-6. 2003
    ..A simple risk-stratification index for patients with ST-segment elevation myocardial infarction derived from an RCT population was recently proposed, but it has not been validated in a community-based cohort...
  73. pmc Neighborhood socioeconomic status influences the survival of elderly patients with myelodysplastic syndromes in the United States
    Rong Wang
    Department of Epidemiology and Public Health, Yale University School of Medicine, 60 College St, Box 208034, New Haven, CT 06520 8034, USA
    Cancer Causes Control 20:1369-76. 2009
    ..In conclusion, this population-based study suggests that neighborhood SES status is a significant and independent determinant of survival among elderly patients with MDS in the United States...
  74. ncbi request reprint Gender differences in the ability to identify a mentor at morning report: a multi-institutional survey
    Anna B Reisman
    Yale University School of Medicine, Section of General Internal Medicine, New Haven, Connecticut, USA
    Teach Learn Med 14:236-9. 2002
    ..However, little is known about the availability of mentors for residents...
  75. pmc The impact of Medicaid coverage and reimbursement on access to diagnostic mammography
    Jeremiah D Schuur
    Robert Wood Johnson Clinical Scholars Program, Veterans Affairs Medical Center, West Haven, Connecticut, USA
    Cancer 115:5566-78. 2009
    ..The objective of the current study was to determine the association between reported insurance type (Medicaid vs Medicare), Medicaid reimbursement rate, and access to diagnostic mammography (DM)...
  76. ncbi request reprint Is the tobacco settlement constitutional?
    Rahul Rajkumar
    Yale University School of Medicine, USA
    J Law Med Ethics 34:748-52. 2006
    ..We consider the merits of the lawsuit, the problems with the MSA that it highlights, and the potential consequences of the suit for public health...
  77. doi request reprint Media exposure and tobacco, illicit drugs, and alcohol use among children and adolescents: a systematic review
    Marcella Nunez-Smith
    Section of General Internal Medicine, Department of Internal Medicine, and Robert Wood Johnson Clinical Scholars Program, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Subst Abus 31:174-92. 2010
    ..Substantial variability in methodological rigor across studies and expanding definitions of media exposure contribute to persistent gaps in the knowledge base...
  78. ncbi request reprint Improving clinical productivity in the academic setting: a novel incentive plan based on utility theory
    Madeline S Wilson
    Yale Internal Medicine Associates, Yale School of Medicine, 789 Howard Ave, Dana 3, New Haven, CT 06510, USA
    Acad Med 81:306-13. 2006
    ....
  79. pmc Use of hospital-based acute care among patients recently discharged from the hospital
    Anita A Vashi
    Robert Wood Johnson Foundation Clinical Scholars Program, Department of Emergency Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    JAMA 309:364-71. 2013
    ..Emergency department (ED) visits are also a marker of hospital-based acute care following discharge but little is known about ED use during this period...
  80. pmc Sharing of clinical trial data among trialists: a cross sectional survey
    Vinay Rathi
    Yale University School of Medicine, New Haven, CT 0520, USA
    BMJ 345:e7570. 2012
    ..To investigate clinical trialists' opinions and experiences of sharing of clinical trial data with investigators who are not directly collaborating with the research team...
  81. pmc Use of complementary medications among older adults with cancer
    Ronald J Maggiore
    Department of Medicine, Sections of Geriatrics Palliative Medicine and Hematology Oncology, University of Chicago Medical Center, Chicago, Illinois, USA
    Cancer 118:4815-23. 2012
    ..The objective of this study was to evaluate the prevalence of complementary medication use and to identify the factors associated with its use among older adults with cancer...
  82. doi request reprint Outcomes of referral to dermatology for suspicious lesions: implications for teledermatology
    Kate V Viola
    Robert Wood Johnson Clinical Scholars Program, Yale University School of Medicine, New Haven, Connecticut, USA
    Arch Dermatol 147:556-60. 2011
    ..To determine the proportion of suspicious lesions referred by nondermatologists that are found to be malignant and the number of incidental skin cancers identified at the time of dermatology referral...
  83. ncbi request reprint Effect of blinded peer review on abstract acceptance
    Joseph S Ross
    Robert Wood Johnson Clinical Scholars Program, Department of Internal Medicine, Yale University School of Medicine and Yale New Haven Hospital Center for Outcomes Research and Evaluation, New Haven, Conn 06520 8088, USA
    JAMA 295:1675-80. 2006
    ..Peer review should evaluate the merit and quality of abstracts but may be biased by geographic location or institutional prestige. The effectiveness of blinded peer review at reducing bias is unknown...
  84. doi request reprint Regional variation in total cost per radical prostatectomy in the healthcare cost and utilization project nationwide inpatient sample database
    Danil V Makarov
    Robert Wood Johnson Clinical Scholars Program, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Urol 183:1504-9. 2010
    ..We determined whether state level variation in the cost of radical prostatectomy exists and whether we could explain this variation by adjusting for covariates associated with cost...
  85. doi request reprint Laparoscopic colectomy for the treatment of cancer has been widely adopted in the United States
    Justin Fox
    Robert Wood Johnson Foundation Clinical Scholars Program, Yale University School of Medicine, New Haven, Connecticut, USA
    Dis Colon Rectum 55:501-8. 2012
    ..This estimate, however, may be artificially low because of inaccurate case identification...
  86. pmc Anesthesiologist involvement in screening colonoscopy: temporal trends and cost implications in the medicare population
    Vijay S Khiani
    Digestive Diseases, Yale School of Medicine, New Haven, Connecticut, USA
    Clin Gastroenterol Hepatol 10:58-64.e1. 2012
    ..We conducted a retrospective study of Medicare data to determine the frequency of anesthesiologist involvement and to identify patient and provider characteristics and cost implications associated with anesthesiologist involvement...
  87. pmc Integrating teaching skills and clinical content in a faculty development workshop
    Michael L Green
    Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA
    J Gen Intern Med 18:468-74. 2003
    ..Integrating clinical content with clinical teaching in a faculty development workshop is feasible, can improve clinical and teaching skills, and can facilitate behavior change...
  88. ncbi request reprint Scope and impact of financial conflicts of interest in biomedical research: a systematic review
    Justin E Bekelman
    Department of Medicine, Yale University School of Medicine, New Haven, Conn 06520, USA
    JAMA 289:454-65. 2003
    ..Despite increasing awareness about the potential impact of financial conflicts of interest on biomedical research, no comprehensive synthesis of the body of evidence relating to financial conflicts of interest has been performed...
  89. pmc Recruiting vulnerable populations into research: a systematic review of recruitment interventions
    Stacy J UyBico
    Section of General Internal Medicine, Yale University School of Medicine, New Haven, CT, USA
    J Gen Intern Med 22:852-63. 2007
    ..Members of vulnerable populations are underrepresented in research studies...
  90. pmc Polypharmacy in older adults with cancer
    Ronald J Maggiore
    Yale Comprehensive Cancer Center and Yale University School of Medicine, New Haven, Connecticut, USA
    Oncologist 15:507-22. 2010
    ..We also examine the strengths and weaknesses of these definitions and explore the relationships among these definitions and what is known about the prevalence and impact of polypharmacy...
  91. ncbi request reprint Radiosurgery alone for 5 or more brain metastases: expert opinion survey
    Jonathan P S Knisely
    Department of Therapeutic Radiology, Yale University School of Medicine and Yale Cancer Center, New Haven, Connecticut 06520 8040, USA
    J Neurosurg 113:84-9. 2010
    ..A survey was conducted at 2 radiosurgery meetings to determine which factors SRS practitioners emphasize in recommending SRS alone, and what physician characteristics are associated with recommending SRS alone for ≥ 5 metastases...
  92. doi request reprint Validation of the partin nomogram for prostate cancer in a national sample
    James B Yu
    Department of Therapeutic Radiology, Yale School of Medicine, New Haven, Connecticut, USA
    J Urol 183:105-11. 2010
    ..The nomogram is based on patients undergoing radical prostatectomy at The Johns Hopkins Medical Institutions. We validated the Partin tables in a large, population based sample...
  93. doi request reprint Cognitive effects of hormonal therapy in older adults
    Nicholas Mitsiades
    Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Semin Oncol 35:569-81. 2008
    ....
  94. doi request reprint The shortage of on-call surgical specialist coverage: a national survey of emergency department directors
    Mitesh B Rao
    Robert Wood Johnson Clinical Scholars Program, Yale University School of Medicine, New Haven, CT, USA
    Acad Emerg Med 17:1374-82. 2010
    ..The objective was to report the experiences of a national sample of ED directors regarding the degree of difficulty in providing specialist coverage and the effect of on-call coverage problems on emergency patient care...
  95. ncbi request reprint The adoption of ablation therapy for Barrett's esophagus: a cohort study of gastroenterologists
    Cary P Gross
    Primary Care Center, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Am J Gastroenterol 97:279-86. 2002
    ..We aimed to determine whether the use of ablation was increasing in a cohort of gastroenterologists, and to identify physician beliefs and characteristics associated with ablation use...
  96. pmc The relation between projected breast cancer risk, perceived cancer risk, and mammography use. Results from the National Health Interview Survey
    C P Gross
    Department of Medicine, Sections of General Internal Medicine, Yale University School of Medicine, New Haven, Conn, USA
    J Gen Intern Med 21:158-64. 2006
    ..Although the use of mammography on at regular intervals can save lives, not all women obtain the repeat mammography recommended in guidelines...
  97. ncbi request reprint The relation between funding by the National Institutes of Health and the burden of disease
    C P Gross
    Robert Wood Johnson Clinical Scholars Program, Johns Hopkins University School of Medicine, Baltimore, USA
    N Engl J Med 340:1881-7. 1999
    ..The Institute of Medicine has proposed that the amount of disease-specific research funding provided by the National Institutes of Health (NIH) be systematically and consistently compared with the burden of disease for society...
  98. ncbi request reprint The impact of practice guidelines in the management of Barrett esophagus: a national prospective cohort study of physicians
    M Cruz-Correa
    The Johns Hopkins Hospital, Blalock 413, 600 N Wolfe St, Baltimore, MD 21287, USA
    Arch Intern Med 161:2588-95. 2001
    ..Our objective is to assess physicians' awareness of agreement with and adherence to these guidelines...
  99. ncbi request reprint Patients' views on financial conflicts of interest in cancer research trials
    Lindsay A Hampson
    Department of Clinical Bioethics, Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA
    N Engl J Med 355:2330-7. 2006
    ..Financial ties between researchers or medical centers and companies whose drugs are being tested have come under increasing scrutiny...
  100. ncbi request reprint Use of postmastectomy radiotherapy in older women
    Benjamin D Smith
    Radiation Oncology Flight, Wilford Hall Medical Center, Lackland Air Force Base, TX, USA
    Int J Radiat Oncol Biol Phys 71:98-106. 2008
    ..Using the Surveillance, Epidemiology, and End Results-Medicare cohort, we sought to characterize the adoption of PMRT from 1992 to 2002 and identify risk factors for PMRT omission among high-risk older patients...
  101. ncbi request reprint Most hospitalized older persons do not meet the enrollment criteria for clinical trials in heart failure
    Frederick A Masoudi
    Division of Cardiology, Denver Health Medical Center, Denver, Colo 80204, USA
    Am Heart J 146:250-7. 2003
    ..Our objective was to determine the proportion of older persons meeting enrollment criteria of randomized controlled trials of agents that prolong life in heart failure...

Research Grants3

  1. The Impact of Comorbidity on Older Cancer Patients
    Cary Gross; Fiscal Year: 2007
    ....
  2. Barriers to Enrolling the Elderly in Cancer Trials
    Cary Gross; Fiscal Year: 2004
    ..It is our hope that this work will facilitate the development of targeted and novel approaches to overcoming these barriers. ..
  3. Use and Outcomes of Radiation Therapy for Medicare Patients with Common Cancers
    Cary P Gross; Fiscal Year: 2010
    ....