Genomes and Genes
E L Grigorenko
Affiliation: Yale University
- Hyperlexia in children with autism spectrum disordersTina M Newman
PACE Center, New Haven, CT 06511, USA
J Autism Dev Disord 37:760-74. 2007..Yet, the study revealed some dissimilarities between these two types of reading when more fine-grained cognitive and linguistic abilities were considered; these dissimilarities warrant further investigations...
- Speaking genes or genes for speaking? Deciphering the genetics of speech and languageElena L Grigorenko
Yale University, Child Study Center, 230 South Frontage Road, New Haven, CT 06519 1124, USA
J Child Psychol Psychiatry 50:116-25. 2009..This article selectively reviews the status of the genetic research in the field of speech and language disorders...
- Risk factors and resilience in the developing world: one of many lessons to learnElena L Grigorenko
Child Study Center, Yale University, New Haven, CT 06520 7900, USA
Dev Psychopathol 19:747-65. 2007..It constitutes an important indicator of resilience in overcoming difficulties related to growing up and being educated under the pressure of the multiple risk factors characteristic of the developing world...
- Exploring interactive effects of genes and environments in etiology of individual differences in reading comprehensionElena L Grigorenko
Child Study Center, Yale University, 230 South Frontage Road, New Haven, CT 06519, USA
Dev Psychopathol 19:1089-103. 2007..These findings were supported by the results of the haplotype analyses, in which the four investigated polymorphisms were considered simultaneously...
- The inherent complexities of gene-environment interactionsElena L Grigorenko
Yale University, PACE Center, Yale University, New Haven, CT 06520 8358, USA
J Gerontol B Psychol Sci Soc Sci 60:53-64. 2005..Fourth, various types of gene-environment interactions are briefly discussed. Fifth, concluding remarks are offered, and possibilities of studying gene-environment interaction within social and biological research on aging are outlined...
- Rethinking disorders of spoken and written language: generating workable hypothesesElena L Grigorenko
Department of Psychology, Yale University, New Haven, CT, USA
J Dev Behav Pediatr 28:478-86. 2007..The purpose of this article is to explore this multilayer overlap and to consider whether such a positive manifold can be explained by one or all of the three hypotheses delineated in the article...
- Aggressive behavior, related conduct problems, and variation in genes affecting dopamine turnoverElena L Grigorenko
Yale University Child Study Center, New Haven, Connecticut 06519, USA
Aggress Behav 36:158-76. 2010....
- At the height of fashion: what genetics can teach us about neurodevelopmental disabilitiesElena L Grigorenko
Child Study Center, Yale University, New Haven, Connecticut 06519 1124, USA
Curr Opin Neurol 22:126-30. 2009..The last decade has generated much interest in the genetics of developmental disorders. This interest, in part, is focused on two issues: the specificity/generality and the type/frequency of the genetic mechanisms involved...
- Behavior, brain, and genome in genomic disorders: finding the correspondencesElena L Grigorenko
Yale University, New Haven, CT, USA
J Dev Behav Pediatr 31:602-9. 2010..This article comments on observations that have been made based on these recent data and discusses their importance for the field of investigations into developmental disorders...
- Annotation: Hyperlexia: disability or superability?Elena L Grigorenko
Child Study Center, Yale University, New Haven, CT 06510, USA
J Child Psychol Psychiatry 44:1079-91. 2003..Hyperlexia is the phenomenon of spontaneous and precocious mastery of single-word reading that has been of interest to clinicians and researchers since the beginning of the last century...
- The first candidate gene for dyslexia: Turning the page of a new chapter of researchElena L Grigorenko
Child Study Center, Yale Medical School, and Center for the Psychology of Abilities, Competencies, and Expertise, Yale University, New Haven, CT 06520, USA
Proc Natl Acad Sci U S A 100:11190-2. 2003
- Continuing the search for dyslexia genes on 6pElena L Grigorenko
PACE Center, Yale University, 340 Edwards Street, New Haven, CT 06511, USA
Am J Med Genet B Neuropsychiatr Genet 118:89-98. 2003..Second, the DD-related linkage in 6p21.3 appears to be most closely related to the manifestations of DD through phonemic awareness and single-word reading deficits...
- Cross-informant symptoms from CBCL, TRF, and YSR: trait and method variance in a normative sample of Russian youthsElena L Grigorenko
Child Study Center, Yale University, New Haven, CT 06519, USA
Psychol Assess 22:893-911. 2010..These results, once again, attest to the importance of incorporating information from multiple observers when psychopathological traits are evaluated in children and adolescents...
- A descriptive study of hyperlexia in a clinically referred sample of children with developmental delaysElena L Grigorenko
Department of Psychology, Child Study Center, Yale University, New Haven, CT 06520 8205, USA
J Autism Dev Disord 32:3-12. 2002..The range of IQ and other cognitive skills and the developmental outcomes of children with hyperlexia were comparable to those of children without hyperlexia...
- Linkage studies suggest a possible locus for developmental dyslexia on chromosome 1pE L Grigorenko
Department of Psychology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
Am J Med Genet 105:120-9. 2001....
- Macrophage migration inhibitory factor and autism spectrum disordersElena L Grigorenko
Child Study Center, Department ofPsychology, Yale University, New Haven, Connecticut 06519, USA
Pediatrics 122:e438-45. 2008....
- Developmental dyslexia: an update on genes, brains, and environmentsE L Grigorenko
Psychology Department, Yale University, New Haven, CT 06520 8205, USA
J Child Psychol Psychiatry 42:91-125. 2001....
- Dynamic assessment and response to intervention: two sides of one coinElena L Grigorenko
Yale University, 230 South Frontage Road, New Haven, CT 06519, USA
J Learn Disabil 42:111-32. 2009..Because DT/A has been around much longer than RTI, it makes sense for the proponents of RTI to consider both the accomplishments and frustrations that have accumulated in the field of DT/A...
- Learning disabilities in juvenile offendersElena L Grigorenko
Child Study Center, Yale Medical School, New Haven, CT, USA
Child Adolesc Psychiatr Clin N Am 15:353-71, viii. 2006..Third, it discusses studies of postrelease academic profiles of juvenile offenders. The article closes with a comment on possible future directions of the research linking reduced levels of academic achievement and delinquency...
- Susceptibility loci for distinct components of developmental dyslexia on chromosomes 6 and 15E L Grigorenko
Department of Psychology, Yale University, New Haven, CT, USA
Am J Hum Genet 60:27-39. 1997....
- Variation in the catechol-O-methyltransferase Val 158 Met polymorphism associated with conduct disorder and ADHD symptoms, among adolescent male delinquentsColin G DeYoung
Department of Psychology, University of Minnesota, Minnesota, USA
Psychiatr Genet 20:20-4. 2010..In addition, because previous research suggests that COMT may be associated with ADHD in males, association between COMT and ADHD symptoms was examined...
- Human GABA(B) receptor 1 gene: eight novel sequence variantsF M Hisama
Department of Neurology, Yale University School of Medicine, New Haven, Connecticut 06520 8018, USA
Hum Mutat 17:349-50. 2001..These DNA variants may be useful in association and linkage studies of neurobehavioral disorders, and in pharmacogenetic studies of drugs targeting GABBR1...
- Same or different? Insights into the etiology of phonological awareness and rapid namingAdam J Naples
Department of Psychology, Yale University, New Haven, CT 06510, USA
Biol Psychol 80:226-39. 2009..The findings of both studies were interpreted according to established theories of reading and our own understanding of the etiology of complex developmental disorders...
- Genes controlling affiliative behavior as candidate genes for autismCarolyn M Yrigollen
Department of Statistics, Department of Epidemiology and PublicHealth, Yale University, Newhaven, CT 06519 1124, USA
Biol Psychiatry 63:911-6. 2008..Autism spectrum disorders (ASD) are neurodevelopmental disorders of complex etiology, with a recognized substantial contribution of heterogeneous genetic factors; one of the core features of ASD is a lack of affiliative behaviors...
- Long-term effects of HIV counseling and testing for women: behavioral and psychological consequences are limited at 18 months posttestJ R Ickovics
Department of Epidemiology and Public Health, Yale University, New Haven, Connecticut 06520 8034, USA
Health Psychol 17:395-402. 1998..HIV counseling and testing should be considered one aspect of a broader program of HIV prevention. Identification of alternative interventions must be a public health priority...
- Intelligence and culture: how culture shapes what intelligence means, and the implications for a science of well-beingRobert J Sternberg
PACE Center, Department of Psychology, Yale University, Box 208358, New Haven, CT 06520, USA
Philos Trans R Soc Lond B Biol Sci 359:1427-34. 2004..It then describes the theory of successful intelligence, which motivates our work on the interface between culture and intelligence. Finally, the article draws some conclusions...
- Intelligence, race, and geneticsRobert J Sternberg
PACE Center, Yale University, New Haven, CT 208358, USA
Am Psychol 60:46-59. 2005..The authors also show that heritability, a behavior-genetic concept, is inadequate in regard to providing such a link...
- Regulation of cerebral cortical size and neuron number by fibroblast growth factors: implications for autismFlora M Vaccarino
Child Study Center, Yale University School of Medicine, 230 South Frontage Rd, New Haven, CT 06520, USA
J Autism Dev Disord 39:511-20. 2009..Thus, many risk factors may converge upon FGF-regulated pathogenetic pathways, which alter excitatory/inhibitory balance and cortical modular architecture, and predispose to autism spectrum disorders...
- Developing a SNP panel for forensic identification of individualsKenneth K Kidd
Department of Genetics, Yale University School of Medicine, New Haven, CT 06520, USA
Forensic Sci Int 164:20-32. 2006..Expansion of this panel to approximately 50 comparable SNPs should give match probabilities of about 10(-15) with a small global range...
- Phonological awareness predicts activation patterns for print and speechStephen J Frost
Haskins Laboratories, 300 George Street, New Haven, CT 06511, USA
Ann Dyslexia 59:78-97. 2009....
- Platelet MAO-B, personality, and psychopathologyVladislav V Ruchkin
Yale Child Study Center, Yale University School of Medicine, New Haven, CT 06520 7900, USA
J Abnorm Psychol 114:477-82. 2005..Future studies should help clarify the nature of the relationships between personality, biological markers, and psychopathology...
- Annual Research Review: The promise of stem cell research for neuropsychiatric disordersFlora M Vaccarino
Child Study Center, Department of Neurobiology, Yale University School of Medicine, New Haven, CT 06520, USA
J Child Psychol Psychiatry 52:504-16. 2011....
- Teaching children with autism to read for meaning: challenges and possibilitiesJudi Randi
University of New Haven, West Haven, CT, USA
J Autism Dev Disord 40:890-902. 2010..These children can especially benefit from interventions addressing particular cognitive processes, such as locating antecedent events, generating and answering questions, locating referents, and rereading to repair understanding...
- Twenty-one-base-pair insertion polymorphism creates an enhancer element and potentiates SLC6A1 GABA transporter promoter activityRungnapa Hirunsatit
Department of Psychiatry and the Yale Keck Center, Yale University School of Medicine, New Haven, CT 06511 6624, USA
Pharmacogenet Genomics 19:53-65. 2009..Here we sought to determine the functional relevance of this variation...
- Cognitive vulnerability to depression: exploring risk and resilienceGerald J Haeffel
Department of Psychology, University of Notre Dame, Notre Dame, IN 46556, USA
Child Adolesc Psychiatr Clin N Am 16:435-48, x. 2007....
- Association between polymorphisms in the dopamine transporter gene and depression: evidence for a gene-environment interaction in a sample of juvenile detaineesGerald J Haeffel
University of Notre Dame, Notre Dame, IN 46556, USA
Psychol Sci 19:62-9. 2008..These results highlight the need for further research investigating the moderating effects of dopaminergic genes on depression...
- Alleles of a reelin CGG repeat do not convey liability to autism in a sample from the CPEA networkBernie Devlin
Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Am J Med Genet B Neuropsychiatr Genet 126:46-50. 2004..Neither is significantly associated with Reelin alleles. Our results are not consistent with a major role for Reelin alleles in liability to autism...
- No evidence for linkage of liability to autism to HOXA1 in a sample from the CPEA networkBernie Devlin
Department of Psychiatry, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania, USA
Am J Med Genet 114:667-72. 2002..Therefore, although we cannot exclude the possibility that the samples in the two studies are intrinsically different, our data from our sample argue against a major role for HOXA1 (His)73(Arg) in liability to autism...
- Genetic Bases of Developmental Language DisordersElena L Grigorenko; Fiscal Year: 2010..abstract_text> ..