Travis J Gould
Affiliation: Yale University
- Auto-aligning stimulated emission depletion microscope using adaptive opticsTravis J Gould
Department of Cell Biology, Yale School of Medicine, 333 Cedar Street, New Haven, Connecticut 06510, USA
Opt Lett 38:1860-2. 2013..We demonstrate here that adaptive optics can be implemented to automatically align STED and confocal images with a precision of 4.3 ± 2.3 nm...
- Nanoscopy at low light intensities shows its potentialTravis J Gould
is in the Department of Cell Biology and the Kavli Institute for Neuroscience, Yale University School of Medicine, New Haven, United States
elife 1:e00475. 2012..A new form of green fluorescent protein allows super-resolution imaging to be performed faster on living cells with low radiation doses...
- Optical nanoscopy: from acquisition to analysisTravis J Gould
Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06510, USA
Annu Rev Biomed Eng 14:231-54. 2012..Furthermore, we provide an overview of existing analysis strategies and discuss their application...
- Adaptive optics enables 3D STED microscopy in aberrating specimensTravis J Gould
Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06520, USA
Opt Express 20:20998-1009. 2012..Here we present the first implementation of adaptive optics in STED microscopy to allow 3D super-resolution imaging in strongly aberrated imaging conditions, such as those introduced by thick biological tissue...
- Quantitative pupil analysis in stimulated emission depletion microscopy using phase retrievalEmil B Kromann
Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
Opt Lett 37:1805-7. 2012..We show the accuracy of this field representation to be sufficient for reconstructing the STED focus in three dimensions and determining corrective steps...
- High-resolution optical imaging of zebrafish larval ribbon synapse protein RIBEYE, RIM2, and CaV 1.4 by stimulation emission depletion microscopyCaixia Lv
Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT 06520, USA
Microsc Microanal 18:745-52. 2012..The clustering of CACNA1F in these blind fish was no longer observed, but instead showed a diffuse expression in the photoreceptor terminal...
- Lysosome size, motility and stress response regulated by fronto-temporal dementia modifier TMEM106BMassimiliano Stagi
Program in Cellular Neuroscience, Neurodegeneration and Repair, Yale University School of Medicine, New Haven, CT 06536, USA Department of Neurology, Yale University School of Medicine, New Haven, CT 06520, USA
Mol Cell Neurosci 61:226-40. 2014..Thus, neuronal TMEM106B plays a central role in regulating lysosomal size, motility and responsiveness to stress, highlighting the possible role of lysosomal biology in FTLD-TDP. ..