Susan M Goebel-Goody

Summary

Affiliation: Yale University
Country: USA

Publications

  1. doi Genetic manipulation of STEP reverses behavioral abnormalities in a fragile X syndrome mouse model
    S M Goebel-Goody
    Child Study Center, Yale University School of Medicine, New Haven, CT 06519, USA
    Genes Brain Behav 11:586-600. 2012
  2. doi Taking STEPs forward to understand fragile X syndrome
    Susan M Goebel-Goody
    Yale University School of Medicine, New Haven, CT 06520, USA
    Results Probl Cell Differ 54:223-41. 2012
  3. pmc Extrasynaptic NMDA receptors couple preferentially to excitotoxicity via calpain-mediated cleavage of STEP
    Jian Xu
    The Child Study Center, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Neurosci 29:9330-43. 2009
  4. pmc Therapeutic implications for striatal-enriched protein tyrosine phosphatase (STEP) in neuropsychiatric disorders
    Susan M Goebel-Goody
    Child Study Center, Yale University School of Medicine, New Haven, Connecticut, USA
    Pharmacol Rev 64:65-87. 2012

Detail Information

Publications4

  1. doi Genetic manipulation of STEP reverses behavioral abnormalities in a fragile X syndrome mouse model
    S M Goebel-Goody
    Child Study Center, Yale University School of Medicine, New Haven, CT 06519, USA
    Genes Brain Behav 11:586-600. 2012
    ....
  2. doi Taking STEPs forward to understand fragile X syndrome
    Susan M Goebel-Goody
    Yale University School of Medicine, New Haven, CT 06520, USA
    Results Probl Cell Differ 54:223-41. 2012
    ..We also discuss implications for STEP in FXS and other disorders, including Alzheimer's disease. As highlighted here, pharmacological interventions targeting STEP may prove successful for FXS...
  3. pmc Extrasynaptic NMDA receptors couple preferentially to excitotoxicity via calpain-mediated cleavage of STEP
    Jian Xu
    The Child Study Center, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Neurosci 29:9330-43. 2009
    ....
  4. pmc Therapeutic implications for striatal-enriched protein tyrosine phosphatase (STEP) in neuropsychiatric disorders
    Susan M Goebel-Goody
    Child Study Center, Yale University School of Medicine, New Haven, Connecticut, USA
    Pharmacol Rev 64:65-87. 2012
    ..This comprehensive review discusses STEP expression and regulation and highlights how disrupted STEP function contributes to the pathophysiology of diverse neuropsychiatric disorders...