Research Topics
| Janneane F GentSummaryAffiliation: Yale University Country: USA Publications
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Publications
Household mold and dust allergens: exposure, sensitization and childhood asthma morbidityJanneane F Gent
Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06510, USA
Environ Res 118:86-93. 2012..Few studies address concurrent exposures to common household allergens, specific allergen sensitization and childhood asthma morbidity...
Levels of household mold associated with respiratory symptoms in the first year of life in a cohort at risk for asthmaJanneane F Gent
Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06510, USA
Environ Health Perspect 110:A781-6. 2002..We conclude that infants in this high-risk group who are exposed to high levels of Penicillium are at significant risk for wheeze and persistent cough...
Association of low-level ozone and fine particles with respiratory symptoms in children with asthmaJanneane F Gent
Center for Perinatal, Pediatric, and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Conn 06510, USA
JAMA 290:1859-67. 2003..Exposure to ozone and particulate matter of 2.5 microm or less (PM2.5) in air at levels above current US Environmental Protection Agency (EPA) standards is a risk factor for respiratory symptoms in children with asthma...
Symptoms and medication use in children with asthma and traffic-related sources of fine particle pollutionJanneane F Gent
Center for Perinatal, Pediatric and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06510, USA
Environ Health Perspect 117:1168-74. 2009..5))] is a potential factor in the exacerbation of asthma. National air quality particle standards consider total mass, not composition or sources, and may not protect against health impacts related to specific components...
Association of pediatric asthma severity with exposure to common household dust allergensJanneane F Gent
Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, One Church Street, 6th Floor, New Haven, CT 06510, USA
Environ Res 109:768-74. 2009..Reducing exposure to household dust inhalant allergens has been proposed as one strategy to reduce asthma...
Respiratory symptoms among infants at risk for asthma: association with surfactant protein A haplotypesMelinda M Pettigrew
Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, USA
BMC Med Genet 8:15. 2007....
Exposure to NO2 and nitrous acid and respiratory symptoms in the first year of lifeRobert T van Strien
Yale School of Public Health, Center for Perinatal, Pediatric and Environmental Epidemiology, New Haven, Connecticut, USA
Epidemiology 15:471-8. 2004..We estimate the independent effects of exposure to nitrogen dioxide and nitrous acid on respiratory symptoms during the first year of life...
Association of early-onset otitis media in infants and exposure to household mouldMelinda M Pettigrew
Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520 8034, USA
Paediatr Perinat Epidemiol 18:441-7. 2004..We also found associations between day-care outside of the home and birth during the summer or fall season with early otitis media. This study is suggestive of a relationship between otitis media and mould that warrants further study...
Indoor heating sources and respiratory symptoms in nonsmoking womenElizabeth W Triche
Department of Epidemiology and Public Health, Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Yale University School of Medicine, 60 College Street, New Haven, CT 06520 8034, USA
Epidemiology 16:377-84. 2005....
Low-level ozone exposure and respiratory symptoms in infantsElizabeth W Triche
Yale Center for Perinatal, Pediatric, and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06520 8034, USA
Environ Health Perspect 114:911-6. 2006..Environmental Protection Agency (EPA) ozone standards may not protect sensitive individuals. In this study we examined respiratory effects of ozone in infants who may be vulnerable, particularly if they are children of asthmatic mothers...
Association of indoor nitrogen dioxide exposure with respiratory symptoms in children with asthmaKathleen Belanger
Yale Center for Perinatal, Pediatric, and Environmental Epidemiology, New Haven, CT 06510, USA
Am J Respir Crit Care Med 173:297-303. 2006..Chronic exposure to indoor nitrogen dioxide (NO2) is a public health concern. Over half of U.S. households have a source of NO2, and experimental data suggest potential for adverse respiratory effects...
Upper respiratory tract microbial communities, acute otitis media pathogens, and antibiotic use in healthy and sick childrenMelinda M Pettigrew
Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, Connecticut, USA
Appl Environ Microbiol 78:6262-70. 2012..51; 95% CI, 0.31 to 0.83). An increased understanding of polymicrobial interactions will facilitate the development of effective AOM prevention strategies...
Viral-bacterial interactions and risk of acute otitis media complicating upper respiratory tract infectionMelinda M Pettigrew
Yale School of Public Health, Yale School of Medicine, New Haven, CT 06520 8034, USA
J Clin Microbiol 49:3750-5. 2011..Acute otitis media prevention efforts should consider methods for reducing infections caused by respiratory syncytial virus, bocavirus, and adenovirus in addition to acute otitis media bacterial pathogens...
Integrated exposure modeling: a model using GIS and GLMTheodore R Holford
Division of Biostatistics, Department of Epidemiology and Public Health, Yale School of Medicine, New Haven, CT 06520, USA
Stat Med 29:116-29. 2010..In the second example, estimated levels of nitrogen dioxide (NO(2)) from the model, as well as a separate spatial model, were used to analyze traffic-related health effects in a study of 761 infants...
Relationship between birth weight and exposure to airborne fine particulate potassium and titanium during gestationMichelle L Bell
Yale University, School of Forestry and Environmental Studies, 195 Prospect St, New Haven, CT 06511, USA
Environ Res 117:83-9. 2012..Our results indicate that exposure to airborne potassium and titanium during pregnancy is associated with lower birth weight. Associations may relate to chemical components of sources producing K and Ti...
Association of surfactant protein A polymorphisms with otitis media in infants at risk for asthmaMelinda M Pettigrew
Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, USA
BMC Med Genet 7:68. 2006....
Prenatal exposure to fine particulate matter and birth weight: variations by particulate constituents and sourcesMichelle L Bell
Yale University, School of Forestry and Environmental Studies, New Haven, CT 06511, USA
Epidemiology 21:884-91. 2010..Exposure to fine particles (PM2.5) during pregnancy has been linked to lower birth weight; however, the chemical composition of PM2.5 varies widely. The health effects of PM2.5 constituents are unknown...
Household levels of nitrogen dioxide and pediatric asthma severityKathleen Belanger
Center for Perinatal, Pediatric and Environmental Epidemiology, Yale University School of Public Health, New Haven, CT 06510, USA
Epidemiology 24:320-30. 2013..S. households. We investigated the effects of indoor NO2 exposure on asthma severity among an ethnically and economically diverse sample of children, controlling for season and indoor allergen exposure...
Infant otitis media and the use of secondary heating sourcesMelinda M Pettigrew
Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven Connecticut 06520 8034, USA
Epidemiology 15:13-20. 2004..This prospective study investigated the association of exposure to indoor secondary heating sources with otitis media and recurrent otitis media risk in infants...
Microbial communities of the upper respiratory tract and otitis media in childrenAlison S Laufer
Yale School of Public Health, Yale University School of Medicine, New Haven, Connecticut, USA
MBio 2:e00245-10. 2011..Increased understanding of upper respiratory tract microbial communities will contribute to the development of otitis media treatment and prevention strategies...
Capacity of serotype 19A and 15B/C Streptococcus pneumoniae isolates for experimental otitis media: Implications for the conjugate vaccineAlison S Laufer
Division of Epidemiology of Microbial Diseases, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520, United States
Vaccine 28:2450-7. 2010..Serotype 19A is included in new conjugate vaccine formulations while serotype 15B/C is not. Non-capsular vaccine targets will be important in disease prevention efforts...
Microbial interactions during upper respiratory tract infectionsMelinda M Pettigrew
Yale School of Public Health, New Haven, Connecticut 06520 8034, USA
Emerg Infect Dis 14:1584-91. 2008..influenzae and S. aureus. Polymicrobial interactions differed by number and species of bacteria present. Antimicrobial therapy and vaccination strategies targeting specific bacterial species may alter the flora in unforeseen ways...
Peak expiratory flow rate variability is not affected by home combustion sources in a group of nonsmoking womenWilliam S Beckett
Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
Arch Environ Occup Health 61:176-82. 2006..88; 95% CI = 1.59-5.21) and black or Hispanic ethnicity (OR = 2.02; 95% CI = 1.27-3.22), but was not associated with use of any supplementary home combustion sources among either asthmatic or nonasthmatic women...
