S C Gary
Affiliation: Yale University
- BEHAB/brevican: a brain-specific lectican implicated in gliomas and glial cell motilityS C Gary
Section of Neurobiology, Yale University, New Haven, Connecticut 06520 8001, USA
Curr Opin Neurobiol 8:576-81. 1998..It is expressed at high levels during development, in response to injury, and in primary brain tumors. Cleavage of the BEHAB/brevican protein may increase invasion of tumor cells...
- cDNA cloning, chromosomal localization, and expression analysis of human BEHAB/brevican, a brain specific proteoglycan regulated during cortical development and in gliomaS C Gary
Section of Neurobiology, Yale University School of Medicine, New Haven, CT 06510, USA
Gene 256:139-47. 2000..The distinct patterns of regulation of expression of the two isoforms suggest distinct mechanisms of regulation of BEHAB/brevican during development and in glioma...
- Brain-enriched hyaluronan binding (BEHAB)/brevican cleavage in a glioma cell line is mediated by a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) family memberR T Matthews
Section of Neurobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
J Biol Chem 275:22695-703. 2000..These results suggest a novel function for ADAMTS family members in BEHAB/brevican cleavage and glioma and indicate that inhibition of ADAMTS in glioma may provide a novel therapeutic strategy...