Patrick Gallagher

Summary

Affiliation: Yale University
Country: USA

Publications

  1. pmc Granulicatella adiacens and Early-Onset Sepsis in Neonate
    Matthew J Bizzarro
    Yale University School of Medicine, New Haven, Connecticut, USA
    Emerg Infect Dis 17:1971-3. 2011
  2. pmc Abnormalities of the erythrocyte membrane
    Patrick G Gallagher
    Department of Pediatrics, Yale University School of Medicine, 333 Cedar Street, PO Box 208064, New Haven, CT 06520 8064, USA Electronic address
    Pediatr Clin North Am 60:1349-62. 2013
  3. doi request reprint Disorders of red cell volume regulation
    Patrick G Gallagher
    Departments of Pediatrics, Pathology, and Genetics, Yale University School of Medicine, New Haven, Connecticut 06520 8064, USA
    Curr Opin Hematol 20:201-7. 2013
  4. ncbi request reprint A human beta-spectrin gene promoter directs high level expression in erythroid but not muscle or neural cells
    P G Gallagher
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520 8021, USA
    J Biol Chem 274:6062-73. 1999
  5. pmc An insulator with barrier-element activity promotes alpha-spectrin gene expression in erythroid cells
    Patrick G Gallagher
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520 8064, USA
    Blood 113:1547-54. 2009
  6. ncbi request reprint A dinucleotide deletion in the ankyrin promoter alters gene expression, transcription initiation and TFIID complex formation in hereditary spherocytosis
    Patrick G Gallagher
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520 8064, USA
    Hum Mol Genet 14:2501-9. 2005
  7. pmc Erythrocyte disorders in the perinatal period
    Laurie A Steiner
    Division of Perinatal Medicine, Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520 8064, USA
    Semin Perinatol 31:254-61. 2007
  8. ncbi request reprint GATA-1 and Oct-1 are required for expression of the human alpha-hemoglobin-stabilizing protein gene
    Patrick G Gallagher
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520 8021, USA
    J Biol Chem 280:39016-23. 2005
  9. ncbi request reprint Hematologically important mutations: ankyrin variants in hereditary spherocytosis
    Patrick G Gallagher
    Department of Pediatrics, Yale University School of Medicine, 333 Cedar Street, P O Box 208064, New Haven, CT 06520 8064, USA
    Blood Cells Mol Dis 35:345-7. 2005
  10. pmc Determinants of erythrocyte hydration
    Jesse Rinehart
    Department of Genetics, Yale University School of Medicine, New Haven, CT, USA
    Curr Opin Hematol 17:191-7. 2010

Research Grants

  1. Molecular Biology of Erythrocyte Ankyrin
    Patrick G Gallagher; Fiscal Year: 2010
  2. MOLECULAR BIOLOGY OF HUMAN ERYTHROCYTE ALPHA-SPECTRIN
    Patrick Gallagher; Fiscal Year: 2000
  3. RESEARCH IN PERINATAL MEDICINE
    Patrick Gallagher; Fiscal Year: 2007
  4. Molecular Biology of Erythrocyte Ankyrin
    Patrick Gallagher; Fiscal Year: 2007
  5. MOLECULAR BIOLOGY OF HUMAN ERYTHROCYTE ALPHA-SPECTRIN
    Patrick Gallagher; Fiscal Year: 2007
  6. Molecular Biology of Erythrocyte Ankyrin
    Patrick Gallagher; Fiscal Year: 2006
  7. Molecular Biology of Erythrocyte Ankyrin
    Patrick Gallagher; Fiscal Year: 2009
  8. Molecular Biology of Erythrocyte Ankyrin
    Patrick G Gallagher; Fiscal Year: 2010
  9. Molecular Biology of Human Erythrocyte Alpha Spectrin
    Patrick G Gallagher; Fiscal Year: 2010
  10. MOLECULAR BIOLOGY OF HUMAN ERYTHROCYTE ALPHA-SPECTRIN
    Patrick Gallagher; Fiscal Year: 2006

Collaborators

  • BERNARD FORGET
  • Robert I Liem
  • Clinton H Joiner
  • Seon Hee Chang
  • W T Tse
  • C A Hillery
  • Mitchell Weiss
  • Daniel B Costa
  • Gary Felsenfeld
  • Janet L Kwiatkowski
  • Deepa Manwani
  • Swee L Thein
  • Douglas R Higgs
  • Silverio Perrotta
  • Matthew Raab
  • Matthew J Bizzarro
  • Laurie A Steiner
  • David M Bodine
  • Louise Marie Dembry
  • Yelena Maksimova
  • Massimiliano Gaetani
  • E Jennifer Edelman
  • Jose Sangerman
  • Douglas G Nilson
  • Scott C Crable
  • Guo Ping Zhou
  • Amanda P Cline
  • Jesse Rinehart
  • Ellice Y Wong
  • Camila O Dos Santos
  • Whitney Tolpinrud
  • Robert S Baltimore
  • David W Speicher
  • Pilar Frontelo
  • Marko Stefanovic
  • Colin P Johnson
  • Clara Wong
  • Andre M Pilon
  • Kathleen P Anderson
  • Denise E Sabatino
  • S Mootien
  • Tiffany F Frazar
  • Lisa J Garrett
  • Laurent Boulanger
  • Patricia A Farrel
  • Deborah A Callan
  • Richard P Lifton
  • Erol E Gulcicek
  • Vincent Schulz
  • Debasish Raha
  • Milind C Mahajan
  • Sherman M Weissman
  • Suiping Zhou
  • Sara Mootien
  • Xiaomei Wang
  • Sandra Harper
  • Fernando F Costa
  • Rodrigo Secolin
  • Yelena D Maksimova
  • Jon S Morrow
  • Anderson F Cunha
  • Ferdane Kutlar
  • Dennis E Discher
  • Vanessa Ortiz
  • Feride Duru
  • Lisa J Garrett-Beal
  • Holger Karsunky
  • Felix Lohmann
  • Mariann Galdass
  • Nishant Bhasin
  • Jack Van Hoff
  • Nicholas O Markham
  • Erin M Parry
  • Sandy Harper
  • James J Bieker
  • Philip S Low
  • Cigdem Altay
  • Dewang Zhou
  • Tim M Townes
  • Suzan M Hammond
  • R Kirk Rettig
  • Richard Papes
  • Jolinta Lin
  • Robert Su
  • Stacie M Anderson
  • Jessica L Weisbein
  • Michel Garbarz
  • Didier Dhermy

Detail Information

Publications41

  1. pmc Granulicatella adiacens and Early-Onset Sepsis in Neonate
    Matthew J Bizzarro
    Yale University School of Medicine, New Haven, Connecticut, USA
    Emerg Infect Dis 17:1971-3. 2011
    ..G. adiacens has been associated with bacteremia and endovascular, central nervous system, ocular, oral, bone and joint, and genitourinary infections (1-4)...
  2. pmc Abnormalities of the erythrocyte membrane
    Patrick G Gallagher
    Department of Pediatrics, Yale University School of Medicine, 333 Cedar Street, PO Box 208064, New Haven, CT 06520 8064, USA Electronic address
    Pediatr Clin North Am 60:1349-62. 2013
    ..The hereditary elliptocytosis syndromes are the most common primary disorders of erythrocyte membrane proteins. However, most elliptocytosis patients are asymptomatic and do not require therapy. ..
  3. doi request reprint Disorders of red cell volume regulation
    Patrick G Gallagher
    Departments of Pediatrics, Pathology, and Genetics, Yale University School of Medicine, New Haven, Connecticut 06520 8064, USA
    Curr Opin Hematol 20:201-7. 2013
    ..This report reviews recent insights into pathways that influence cellular water and solute homeostasis and cell volume...
  4. ncbi request reprint A human beta-spectrin gene promoter directs high level expression in erythroid but not muscle or neural cells
    P G Gallagher
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520 8021, USA
    J Biol Chem 274:6062-73. 1999
    ..Only weak expression of the reporter gene was detected in muscle and brain tissue, suggesting that additional regulatory elements are required for high level expression of the beta-spectrin gene in these tissues...
  5. pmc An insulator with barrier-element activity promotes alpha-spectrin gene expression in erythroid cells
    Patrick G Gallagher
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520 8064, USA
    Blood 113:1547-54. 2009
    ..These data identify the first barrier element described in an erythrocyte membrane protein gene and indicate that exon 1' and intron 1' are excellent candidate regions for mutations in patients with spectrin-linked hemolytic anemia...
  6. ncbi request reprint A dinucleotide deletion in the ankyrin promoter alters gene expression, transcription initiation and TFIID complex formation in hereditary spherocytosis
    Patrick G Gallagher
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520 8064, USA
    Hum Mol Genet 14:2501-9. 2005
    ....
  7. pmc Erythrocyte disorders in the perinatal period
    Laurie A Steiner
    Division of Perinatal Medicine, Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520 8064, USA
    Semin Perinatol 31:254-61. 2007
    ..This review focuses on the perinatal presentation and management of intrinsic erythrocyte disorders, as well as on the diagnosis and management of genetic conditions leading to erythrocyte underproduction...
  8. ncbi request reprint GATA-1 and Oct-1 are required for expression of the human alpha-hemoglobin-stabilizing protein gene
    Patrick G Gallagher
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520 8021, USA
    J Biol Chem 280:39016-23. 2005
    ..The AHSP promoter is an excellent candidate region for mutations associated with decreased AHSP gene expression...
  9. ncbi request reprint Hematologically important mutations: ankyrin variants in hereditary spherocytosis
    Patrick G Gallagher
    Department of Pediatrics, Yale University School of Medicine, 333 Cedar Street, P O Box 208064, New Haven, CT 06520 8064, USA
    Blood Cells Mol Dis 35:345-7. 2005
    ..In most cases, HS-related ankyrin mutations are private. A summary of reported HS-associated ankyrin gene mutations is provided in this report...
  10. pmc Determinants of erythrocyte hydration
    Jesse Rinehart
    Department of Genetics, Yale University School of Medicine, New Haven, CT, USA
    Curr Opin Hematol 17:191-7. 2010
    ..This study reviews recent progress in our understanding the determinants of erythrocyte hydration and its related disorders...
  11. ncbi request reprint Update on the clinical spectrum and genetics of red blood cell membrane disorders
    Patrick G Gallagher
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520, USA
    Curr Hematol Rep 3:85-91. 2004
    ..Analysis of these defects has provided a better understanding of the pathogenesis of these disorders and allowed a better understanding of the structure/function relationships of the proteins of the erythrocyte membrane...
  12. pmc Mutation of a barrier insulator in the human ankyrin-1 gene is associated with hereditary spherocytosis
    Patrick G Gallagher
    Departments of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA
    J Clin Invest 120:4453-65. 2010
    ..These data indicate that an upstream region of the ankyrin-1 erythroid promoter acts as a barrier insulator and identify disruption of the barrier element as a potential pathogenetic mechanism of human disease...
  13. ncbi request reprint Mutation of a highly conserved isoleucine disrupts hydrophobic interactions in the alpha beta spectrin self-association binding site
    Patrick G Gallagher
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520 8064, USA
    Lab Invest 84:229-34. 2004
    ..Molecular modeling demonstrated that replacement of a hydrophobic isoleucine with a hydrophilic threonine disrupts highly conserved hydrophobic interactions in the interior of the spectrin triple helix critical for spectrin function...
  14. ncbi request reprint Regulation of erythrocyte membrane protein gene expression
    Patrick G Gallagher
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520 8064, USA
    Curr Opin Hematol 10:115-22. 2003
    ..These include disease pathogenesis, membrane assembly, hematopoiesis, gene regulation, and direction of other erythroid-specific genes in transgenic mouse and gene therapy applications...
  15. ncbi request reprint Altered erythrocyte endothelial adherence and membrane phospholipid asymmetry in hereditary hydrocytosis
    Patrick G Gallagher
    Department of Pediatrics, Yale University School of Medicine, PO Box 208064, 333 Cedar St, New Haven, CT 06520 8064
    Blood 101:4625-7. 2003
    ..Increased phosphatidylserine exposure accelerating thrombin-forming processes has been proposed as a mechanism for thrombosis in sickle cell disease and beta-thalassemia and may play a similar role in hereditary hydrocytosis...
  16. ncbi request reprint Erythrocyte ankyrin promoter mutations associated with recessive hereditary spherocytosis cause significant abnormalities in ankyrin expression
    P G Gallagher
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Biol Chem 276:41683-9. 2001
    ..These data are the first demonstration of functional defects caused by HS-related, ankyrin gene promoter mutations...
  17. ncbi request reprint A recurrent frameshift mutation of the ankyrin gene associated with severe hereditary spherocytosis
    P G Gallagher
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520 8064, USA
    Br J Haematol 111:1190-3. 2000
    ..This frameshift mutation associated with severe HS, Ankyrin Florianópolis, is the first description of a recurrent mutation in the ankyrin gene...
  18. ncbi request reprint The human ankyrin-1 gene is selectively transcribed in erythroid cell lines despite the presence of a housekeeping-like promoter
    P G Gallagher
    Departments of Pediatrics, Internal Medicine and Genetics, Yale University School of Medicine, New Haven, CT 06520 8064, USA
    Blood 96:1136-43. 2000
    ..The ankyrin gene erythroid promoter was transactivated in heterologous cells by forced expression of GATA-1 and to a lesser degree BKLF...
  19. ncbi request reprint Sequences downstream of the erythroid promoter are required for high level expression of the human alpha-spectrin gene
    Ellice Y Wong
    Department of Pediatrics and Internal Medicine, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520 8021, USA
    J Biol Chem 279:55024-33. 2004
    ..This is an excellent candidate region for mutations associated with decreased alpha-spectrin gene expression in patients with hereditary spherocytosis and hereditary pyropoikilocytosis...
  20. doi request reprint Ankyrin-linked hereditary spherocytosis in an African-American kindred
    Jose Sangerman
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520 8064, USA
    Am J Hematol 83:789-94. 2008
    ..This is the first report describing ankyrin-linked HS in an African-American kindred...
  21. pmc A novel splicing mutation of the alpha-spectrin gene in the original hereditary pyropoikilocytosis kindred
    Daniel B Costa
    Department of Medicine, Yale University School of Medicine, New Haven, CT, USA
    Blood 106:4367-9. 2005
    ..Following gene transfer into tissue culture cells, there was complete absence of normally spliced alpha-spectrin gene transcripts derived from a minigene containing the IVS 22 +5 mutation...
  22. pmc Chromatin architecture and transcription factor binding regulate expression of erythrocyte membrane protein genes
    Laurie A Steiner
    Department of Pediatrics, Yale University School of Medicine, 333 Cedar Street, P O Box 208064, New Haven, CT 06520 8064, USA
    Mol Cell Biol 29:5399-412. 2009
    ....
  23. ncbi request reprint Hereditary elliptocytosis: spectrin and protein 4.1R
    Patrick G Gallagher
    Department of Pediatrics, Yale University School of Medicine, 333 Cedar Street, PO Box 208064, New Haven, CT 06520 8064, USA
    Semin Hematol 41:142-64. 2004
    ..quot; The majority of HE patients are asymptomatic, but some may experience hemolytic anemia, splenomegaly, and intermittent jaundice...
  24. pmc A complex splicing defect associated with homozygous ankyrin-deficient hereditary spherocytosis
    E Jennifer Edelman
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520 8064, USA
    Blood 109:5491-3. 2007
    ....
  25. ncbi request reprint Human potassium chloride cotransporter 1 (SLC12A4) promoter is regulated by AP-2 and contains a functional downstream promoter element
    Guo Ping Zhou
    Department of Pediatrics, Yale University School of Medicine, PO Box 208064, 333 Cedar St, New Haven, CT 06520 8064, USA
    Blood 103:4302-9. 2004
    ..In vivo studies using chromatin immunoprecipitation assays with antihistone H3 and antihistone H4 antibodies demonstrated hyperacetylation of this core promoter region...
  26. ncbi request reprint Aplastic crisis revealing the diagnosis of Hb Evans [alpha62(E11)Val-->Met, GTG-->ATG (alpha2)] in a Hispanic kindred: case report and review
    Laurie A Steiner
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520 8064, USA
    Hemoglobin 31:409-16. 2007
    ..Literature review indicates aplastic crisis is a rare initial presentation of unstable hemoglobinopathies and that these disorders are infrequent but important causes of hemolytic anemia in Hispanic patients...
  27. pmc Case-control analysis of endemic Serratia marcescens bacteremia in a neonatal intensive care unit
    Matthew J Bizzarro
    Divisions of Perinatal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520 8064, USA
    Arch Dis Child Fetal Neonatal Ed 92:F120-6. 2007
    ..Serratia marcescens is an opportunistic gram-negative rod which typically infects compromised hosts...
  28. doi request reprint Matched case-control analysis of polymicrobial bloodstream infection in a neonatal intensive care unit
    Matthew J Bizzarro
    Division of Perinatal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520 8064, USA
    Infect Control Hosp Epidemiol 29:914-20. 2008
    ..To compare and contrast the epidemiology of polymicrobial and monomicrobial bloodstream infections (BSIs) in newborn intensive care unit (NICU) patients...
  29. pmc Variegated expression from the murine band 3 (AE1) promoter in transgenic mice is associated with mRNA transcript initiation at upstream start sites and can be suppressed by the addition of the chicken beta-globin 5' HS4 insulator element
    Tiffany F Frazar
    Hematopoiesis Section, Genetics and Molecular Biology Branch, National Human Genome Research Institute, Bethesda, Maryland 20892, USA
    Mol Cell Biol 23:4753-63. 2003
    ..We conclude that the chicken beta-globin 5'HS4 element is necessary for full function of the AE1 promoter and that position effect variegation is associated with RNA transcription from the upstream start sites...
  30. ncbi request reprint Erythroid expression of the human alpha-spectrin gene promoter is mediated by GATA-1- and NF-E2-binding proteins
    Laurent Boulanger
    INSERM U409, Association Claude Bernard, Universite Paris 7, Faculte X Bichat, 75870 Paris Cedex 18, France
    J Biol Chem 277:41563-70. 2002
    ..No expression of the reporter gene was detected in nonerythroid tissues. We conclude that this alpha-spectrin gene promoter contains the sequences necessary for low level expression in erythroid progenitor cells...
  31. ncbi request reprint Major erythrocyte membrane protein genes in EKLF-deficient mice
    Douglas G Nilson
    Hematopoiesis Section, Genetics and Molecular Biology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA
    Exp Hematol 34:705-12. 2006
    ..The objectives of this study were to rescue EKLF-deficient embryos with mice expressing gamma-globin from beta-spectrin or ankyrin promoters and to characterize expression of the major erythrocyte membrane genes in EKLF-deficient cells...
  32. pmc Alterations in expression and chromatin configuration of the alpha hemoglobin-stabilizing protein gene in erythroid Kruppel-like factor-deficient mice
    Andre M Pilon
    Hematopoiesis Section, Genetics and Molecular Biology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892 4442, USA
    Mol Cell Biol 26:4368-77. 2006
    ..These results support the hypothesis that EKLF acts as a transcription factor and a chromatin modulator for the AHSP and beta-globin genes and indicate that EKLF may play similar roles for other erythroid genes...
  33. pmc Pathogenic proline mutation in the linker between spectrin repeats: disease caused by spectrin unfolding
    Colin P Johnson
    Molecular and Cell Biophysics Laboratory, University of Pennsylvania, 3699 Market Street, Philadelphia, PA 19104, USA
    Blood 109:3538-43. 2007
    ..The results suggest a molecular mechanism for the high frequency of disease caused by proline mutations in spectrin linkers...
  34. pmc An 11-amino acid beta-hairpin loop in the cytoplasmic domain of band 3 is responsible for ankyrin binding in mouse erythrocytes
    Marko Stefanovic
    Department of Chemistry, Purdue University, 1393 BRWN Building, West Lafayette, IN 47907, USA
    Proc Natl Acad Sci U S A 104:13972-7. 2007
    ..Our data indicate that as yet uncharacterized interactions between other membrane proteins must significantly contribute to linkage of the spectrin-actin-based membrane cytoskeleton to the plasma membrane...
  35. pmc Structural and functional effects of hereditary hemolytic anemia-associated point mutations in the alpha spectrin tetramer site
    Massimiliano Gaetani
    The Wistar Institute, Philadelphia, PA 19104, USA
    Blood 111:5712-20. 2008
    ..All alpha0 HE/HPP mutations studied here appear to exert their destabilizing effects through molecular recognition rather than structural mechanisms...
  36. ncbi request reprint Population analysis of the alpha hemoglobin stabilizing protein (AHSP) gene identifies sequence variants that alter expression and function
    Camila O Dos Santos
    The Children s Hospital of Philadelphia, Division of Hematology, Philadelphia, Pennsylvania 19104, USA
    Am J Hematol 83:103-8. 2008
    ....
  37. ncbi request reprint Hereditary pyropoikilocytosis and the spectrin St. Claude allele
    S Mootien
    Br J Haematol 124:251-2. 2004
  38. pmc Novel role for EKLF in megakaryocyte lineage commitment
    Pilar Frontelo
    Mount Sinai School of Medicine, New York, NY 10029, USA
    Blood 110:3871-80. 2007
    ..Expression profiling and molecular analyses support these observations and suggest that megakaryocytic inhibition is achieved, at least in part, by EKLF repression of Fli-1 message levels...
  39. ncbi request reprint Hereditary spherocytosis
    Silverio Perrotta
    Department of Paediatrics, Second University of Naples, Naples, Italy
    Lancet 372:1411-26. 2008
    ..Common complications are cholelithiasis, haemolytic episodes, and aplastic crises. Splenectomy is curative but should be undertaken only after careful assessment of the risks and benefits...
  40. doi request reprint Nonsense mutations of the alpha-spectrin gene in hereditary pyropoikilocytosis
    Whitney Tolpinrud
    Haematologica 93:1752-4. 2008
  41. ncbi request reprint Multiple isoforms of the KC1 cotransporter are expressed in sickle and normal erythroid cells
    Scott C Crable
    Comprehensive Sickle Cell Center, Division of Hematology Oncology, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229, USA
    Exp Hematol 33:624-31. 2005
    ..As a step toward determining which isoform(s) is responsible for the Cl-dependent K fluxes in reticulocytes, human erythroid cells were examined for the presence of various KCC isoform transcripts...

Research Grants22

  1. Molecular Biology of Erythrocyte Ankyrin
    Patrick G Gallagher; Fiscal Year: 2010
    ..These studies may provide important information to be used for diagnosis and treatment of patients with this disorder. ..
  2. MOLECULAR BIOLOGY OF HUMAN ERYTHROCYTE ALPHA-SPECTRIN
    Patrick Gallagher; Fiscal Year: 2000
    ..These studies will provide important insights into our studies of the role of a-spectrin in normal and disease states. ..
  3. RESEARCH IN PERINATAL MEDICINE
    Patrick Gallagher; Fiscal Year: 2007
    ..It has been recognized that there is a national shortage of suitably trained physician-scientists. The ongoing objective of this program is to train members of the next generation of perinatal investigators. ..
  4. Molecular Biology of Erythrocyte Ankyrin
    Patrick Gallagher; Fiscal Year: 2007
    ..These studies may provide important information to be used for diagnosis and treatment of patients with this disorder. ..
  5. MOLECULAR BIOLOGY OF HUMAN ERYTHROCYTE ALPHA-SPECTRIN
    Patrick Gallagher; Fiscal Year: 2007
    ..These studies will provide important insights into the role of spectrin in normal and disease states. ..
  6. Molecular Biology of Erythrocyte Ankyrin
    Patrick Gallagher; Fiscal Year: 2006
    ..These studies will provide important insights into the role of ankyrin in normal and disease states. ..
  7. Molecular Biology of Erythrocyte Ankyrin
    Patrick Gallagher; Fiscal Year: 2009
    ..These studies may provide important information to be used for diagnosis and treatment of patients with this disorder. ..
  8. Molecular Biology of Erythrocyte Ankyrin
    Patrick G Gallagher; Fiscal Year: 2010
    ..These studies may provide important information to be used for diagnosis and treatment of patients with this disorder. ..
  9. Molecular Biology of Human Erythrocyte Alpha Spectrin
    Patrick G Gallagher; Fiscal Year: 2010
    ..Some people require surgery or blood transfusions to treat the anemia. This application studies the what, why, and how of abnormalities of the lining of the red blood cell that cause the anemia. ..
  10. MOLECULAR BIOLOGY OF HUMAN ERYTHROCYTE ALPHA-SPECTRIN
    Patrick Gallagher; Fiscal Year: 2006
    ..These studies will provide important insights into the role of spectrin in normal and disease states. ..
  11. Molecular Biology of Erythrocyte Ankyrin
    Patrick Gallagher; Fiscal Year: 2004
    ..These studies will provide important insights into the role of ankyrin in normal and disease states. ..
  12. MOLECULAR BIOLOGY OF HUMAN ERYTHROCYTE ALPHA-SPECTRIN
    Patrick Gallagher; Fiscal Year: 2001
    ..These studies will provide important insights into our studies of the role of a-spectrin in normal and disease states. ..
  13. Molecular Biology of Erythrocyte Ankyrin
    Patrick Gallagher; Fiscal Year: 2002
    ..These studies will provide important insights into the role of ankyrin in normal and disease states. ..
  14. MOLECULAR BIOLOGY OF HUMAN ERYTHROCYTE ALPHA-SPECTRIN
    Patrick Gallagher; Fiscal Year: 2002
    ..These studies will provide important insights into our studies of the role of a-spectrin in normal and disease states. ..
  15. Molecular Biology of Erythrocyte Ankyrin
    Patrick Gallagher; Fiscal Year: 2003
    ..These studies will provide important insights into the role of ankyrin in normal and disease states. ..
  16. MOLECULAR BIOLOGY OF HUMAN ERYTHROCYTE ALPHA-SPECTRIN
    Patrick Gallagher; Fiscal Year: 2003
    ..These studies will provide important insights into our studies of the role of a-spectrin in normal and disease states. ..
  17. Molecular Biology of Erythrocyte Ankyrin
    Patrick Gallagher; Fiscal Year: 2004
    ..These studies will provide important insights into the role of ankyrin in normal and disease states. ..
  18. MOLECULAR BIOLOGY OF HUMAN ERYTHROCYTE ALPHA-SPECTRIN
    Patrick Gallagher; Fiscal Year: 2004
    ..These studies will provide important insights into the role of spectrin in normal and disease states. ..
  19. Molecular Biology of Erythrocyte Ankyrin
    Patrick Gallagher; Fiscal Year: 2005
    ..These studies will provide important insights into the role of ankyrin in normal and disease states. ..
  20. MOLECULAR BIOLOGY OF HUMAN ERYTHROCYTE ALPHA-SPECTRIN
    Patrick Gallagher; Fiscal Year: 2005
    ..These studies will provide important insights into the role of spectrin in normal and disease states. ..