Judith M Ford

Summary

Affiliation: Yale University
Country: USA

Publications

  1. pmc Anticipating the future: automatic prediction failures in schizophrenia
    Judith M Ford
    Psychiatry Service, San Francisco VA Medical Center, 4150 Clement Street, San Francisco, CA 94121, USA
    Int J Psychophysiol 83:232-9. 2012
  2. ncbi request reprint Reduced gamma-band coherence to distorted feedback during speech when what you say is not what you hear
    Judith M Ford
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT Psychiatry Service, Veterans Affairs Connecticut Health Care System, West Haven, CT, United States
    Int J Psychophysiol 57:143-50. 2005
  3. ncbi request reprint Synch before you speak: auditory hallucinations in schizophrenia
    Judith M Ford
    Psychiatry Service, Veterans Affairs Connecticut Health Care System, USA
    Am J Psychiatry 164:458-66. 2007
  4. ncbi request reprint Corollary discharge dysfunction in schizophrenia: can it explain auditory hallucinations?
    Judith M Ford
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Int J Psychophysiol 58:179-89. 2005
  5. ncbi request reprint Dissecting corollary discharge dysfunction in schizophrenia
    Judith M Ford
    Psychiatry Service, Veterans Affairs Connecticut Healthcare System, West Haven 06517, and Department of Psychiatry, Yale University School of Medicne, New Haven, Connecticut, USA
    Psychophysiology 44:522-9. 2007
  6. pmc Neural synchrony in schizophrenia: from networks to new treatments
    Judith M Ford
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Schizophr Bull 33:848-52. 2007
  7. pmc Out-of-synch and out-of-sorts: dysfunction of motor-sensory communication in schizophrenia
    Judith M Ford
    Psychiatry Service, Veterans Affairs Connecticut Healthcare System, West Haven, Connecticut, USA
    Biol Psychiatry 63:736-43. 2008
  8. pmc Tuning in to the voices: a multisite FMRI study of auditory hallucinations
    Judith M Ford
    Yale University, West Haven, CT, USA
    Schizophr Bull 35:58-66. 2009
  9. ncbi request reprint Delayed hemodynamic responses in schizophrenia
    Judith M Ford
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06520, USA
    Neuroimage 26:922-31. 2005
  10. ncbi request reprint Early auditory gamma-band responses in patients at clinical high risk for schizophrenia
    Veronica B Perez
    Department of Psychiatry, University of California, San Francisco UCSF, San Francisco, CA 94121, USA
    Suppl Clin Neurophysiol 62:147-62. 2013

Research Grants

  1. Auditory Hallucinations in Schizophrenia: ERPs & fMRI
    Handan Gunduz Bruce; Fiscal Year: 2005
  2. Neurobiology of Response Failure in Schizophrenia
    Judith Ford; Fiscal Year: 2007

Detail Information

Publications47

  1. pmc Anticipating the future: automatic prediction failures in schizophrenia
    Judith M Ford
    Psychiatry Service, San Francisco VA Medical Center, 4150 Clement Street, San Francisco, CA 94121, USA
    Int J Psychophysiol 83:232-9. 2012
    ..These prediction failures characterize the diagnosis of schizophrenia rather than reflecting specific symptoms...
  2. ncbi request reprint Reduced gamma-band coherence to distorted feedback during speech when what you say is not what you hear
    Judith M Ford
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT Psychiatry Service, Veterans Affairs Connecticut Health Care System, West Haven, CT, United States
    Int J Psychophysiol 57:143-50. 2005
    ..We tested the hypothesis that there would be a disruption of gamma-band coherence when the expected auditory consequence of speech does not match the auditory experience...
  3. ncbi request reprint Synch before you speak: auditory hallucinations in schizophrenia
    Judith M Ford
    Psychiatry Service, Veterans Affairs Connecticut Health Care System, USA
    Am J Psychiatry 164:458-66. 2007
    ..If so, schizophrenia patients should have reduced neural synchrony preceding movements, especially patients with severe hallucinations...
  4. ncbi request reprint Corollary discharge dysfunction in schizophrenia: can it explain auditory hallucinations?
    Judith M Ford
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Int J Psychophysiol 58:179-89. 2005
    ....
  5. ncbi request reprint Dissecting corollary discharge dysfunction in schizophrenia
    Judith M Ford
    Psychiatry Service, Veterans Affairs Connecticut Healthcare System, West Haven 06517, and Department of Psychiatry, Yale University School of Medicne, New Haven, Connecticut, USA
    Psychophysiology 44:522-9. 2007
    ..Agency and expectancy had modest suppression effects on N1 and only in controls. Group differences in expectancy and agency could not account for failed corollary discharge during talking in patients...
  6. pmc Neural synchrony in schizophrenia: from networks to new treatments
    Judith M Ford
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Schizophr Bull 33:848-52. 2007
    ..Based on this, we argue that we can begin to use oscillations, across frequencies, to do translational studies to understand the neural basis of schizophrenia...
  7. pmc Out-of-synch and out-of-sorts: dysfunction of motor-sensory communication in schizophrenia
    Judith M Ford
    Psychiatry Service, Veterans Affairs Connecticut Healthcare System, West Haven, Connecticut, USA
    Biol Psychiatry 63:736-43. 2008
    ..If it reflects the action of the efference copy, it should be related to subsequent sensory suppression. If efference copy/corollary discharge mechanisms are abnormal in schizophrenia, it should be reduced in patients with schizophrenia...
  8. pmc Tuning in to the voices: a multisite FMRI study of auditory hallucinations
    Judith M Ford
    Yale University, West Haven, CT, USA
    Schizophr Bull 35:58-66. 2009
    ..Accordingly, we predicted that patients who hallucinate would show less auditory cortical activation to external acoustic stimuli than patients who did not...
  9. ncbi request reprint Delayed hemodynamic responses in schizophrenia
    Judith M Ford
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06520, USA
    Neuroimage 26:922-31. 2005
    ....
  10. ncbi request reprint Early auditory gamma-band responses in patients at clinical high risk for schizophrenia
    Veronica B Perez
    Department of Psychiatry, University of California, San Francisco UCSF, San Francisco, CA 94121, USA
    Suppl Clin Neurophysiol 62:147-62. 2013
    ....
  11. ncbi request reprint Selective attention in schizophrenia: sparing and loss of executive control
    Daniel H Mathalon
    Psychiatry Service 116A, VA Connecticut Healthcare System, 950 Campbell Ave, West Haven, CT 06516, USA
    Am J Psychiatry 161:872-81. 2004
    ..Patients with schizophrenia have deficits in auditory selective attention, but whether these attention deficits are evident at the earliest stages of auditory processing or emerge later in the processing stream is unknown...
  12. pmc Auditory cortex responsiveness during talking and listening: early illness schizophrenia and patients at clinical high-risk for psychosis
    Veronica B Perez
    Department of Psychiatry, University of California, San Francisco UCSF, San Francisco, CA 94121, USA
    Schizophr Bull 38:1216-24. 2012
    ..Whether this abnormality precedes psychosis onset, emerges early in the illness, and/or progressively worsens with illness chronicity, is unknown...
  13. pmc Error detection failures in schizophrenia: ERPs and FMRI
    Daniel H Mathalon
    Psychiatry Service, San Francisco VA Medical Center, and Department of Psychiatry, University of California San Francisco, 4150 Clement Street, San Francisco, CA 94121, USA
    Int J Psychophysiol 73:109-17. 2009
    ....
  14. doi request reprint Automatic semantic priming abnormalities in schizophrenia
    Daniel H Mathalon
    Psychiatry Service, Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    Int J Psychophysiol 75:157-66. 2010
    ....
  15. pmc Error monitoring dysfunction across the illness course of schizophrenia
    Veronica B Perez
    Department of Psychiatry, University of California, San Francisco, San Francisco, CA 94143, USA
    J Abnorm Psychol 121:372-87. 2012
    ..Brain regions subserving response monitoring may be compromised early in the illness and possibly during its clinical prodrome...
  16. pmc Glutamatergic modulation of auditory information processing in the human brain
    Handan Gunduz-Bruce
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
    Biol Psychiatry 71:969-77. 2012
    ..On the basis of these findings, we tested whether NAC would reduce ketamine effects on behavior, MMN, and P300 in healthy humans...
  17. pmc The dependence of P300 amplitude on gamma synchrony breaks down in schizophrenia
    Judith M Ford
    Psychiatry Service, San Francisco VA Medical Center, Department of Psychiatry, University of California, San Francisco, CA 94121, USA
    Brain Res 1235:133-42. 2008
    ..We also asked whether people who have large P300s have higher power and greater synchrony of neural activity, and if the relationships between P300 and power and synchrony are different in patients and healthy controls...
  18. ncbi request reprint Response-monitoring dysfunction in aging and Alzheimer's disease: an event-related potential study
    Daniel H Mathalon
    Department of Psychiatry, Psychiatry Service 116A, Veterans Affairs Connecticut Healthcare System, 950 Campbell Avenue, West Haven, CT 06516, USA
    Neurobiol Aging 24:675-85. 2003
    ..In AD patients, CRN amplitude was affected by item certainty (assessed a week earlier), being larger to items that were idiosyncratically difficult for patients to name...
  19. ncbi request reprint Corollary discharge dysfunction in schizophrenia: evidence for an elemental deficit
    Daniel H Mathalon
    Psychiatry Service, San Francisco VA Medical Center, USA
    Clin EEG Neurosci 39:82-6. 2008
    ....
  20. pmc Assessing corollary discharge in humans using noninvasive neurophysiological methods
    Judith M Ford
    Department of Psychiatry, San Francisco VA Medical Center, University of California, San Francisco, California, USA
    Nat Protoc 5:1160-8. 2010
    ..The successful action of the corollary discharge is seen when the response of the auditory cortex is suppressed during the Talk compared with the Listen condition. The protocol takes about 5 min to complete...
  21. pmc Impaired visual cortical plasticity in schizophrenia
    Idil Cavus
    Department of Psychiatry, Yale University, New Haven, Connecticut
    Biol Psychiatry 71:512-20. 2012
    ..Using this paradigm, we examined whether visual cortical plasticity is impaired in SZ...
  22. ncbi request reprint N400 and automatic semantic processing abnormalities in patients with schizophrenia
    Daniel H Mathalon
    Department of Psychiatry, VA Connecticut Healthcare System, West Haven 06516, USA
    Arch Gen Psychiatry 59:641-8. 2002
    ..Using N400, inferences can be drawn regarding the extent to which a given context primes a word...
  23. ncbi request reprint Anatomy of an error: ERP and fMRI
    Daniel H Mathalon
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Biol Psychol 64:119-41. 2003
    ..Thus, error and conflict monitoring may be dissociable, subserved by both overlapping and distinct ACC regions...
  24. ncbi request reprint When it's time for a change: failures to track context in schizophrenia
    Judith M Ford
    Psychiatry Service, San Francisco VA Medical Center, USA
    Int J Psychophysiol 78:3-13. 2010
    ..The improbable occurrence of a standard should generate a P300, but only if the implicit local context generated by the recent stimulus history is processed...
  25. pmc Automatic auditory processing deficits in schizophrenia and clinical high-risk patients: forecasting psychosis risk with mismatch negativity
    Veronica B Perez
    University of California, San Francisco, California San Francisco Veterans Administration Medical Center, San Francisco, California
    Biol Psychiatry 75:459-69. 2014
    ..We also examined whether MMN predicted subsequent conversion to psychosis in CHR patients...
  26. pmc Neurophysiological studies of auditory verbal hallucinations
    Judith M Ford
    Psychiatry Service, San Francisco Veterans Affairs Medical Center, Department of Psychiatry, University of California, San Francisco, CA, USA
    Schizophr Bull 38:715-23. 2012
    ..These problems are common to studies of other psychiatric symptoms and should be considered when attempting to understand the basic neural mechanisms responsible for them...
  27. ncbi request reprint The long and the short of it: influence of interstimulus interval on auditory P300 abnormalities in schizophrenia
    Daniel H Mathalon
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
    Clin Electroencephalogr 33:125-35. 2002
    ..Implications for the cognitive significance of the P300 and its reduction in schizophrenia are discussed...
  28. pmc Relationships between pre-stimulus γ power and subsequent P300 and reaction time breakdown in schizophrenia
    Robert M G Reinhart
    Yale University, New Haven, CT, United States
    Int J Psychophysiol 79:16-24. 2011
    ....
  29. pmc Neurophysiological evidence of corollary discharge function during vocalization in psychotic patients and their nonpsychotic first-degree relatives
    Judith M Ford
    To whom correspondence should be addressed Psychiatry Service 116D, San Francisco VA Medical Center, 4150 Clement Street, San Francisco, CA 94121, US tel 415 221 4810, ext 4187, fax 415 750 6622, E mail
    Schizophr Bull 39:1272-80. 2013
    ..Data from unaffected family members do not indicate that this is a marker of psychosis risk. ..
  30. pmc Neural synchrony in schizophrenia
    Judith M Ford
    Department of Psychiatry, University of California San Francisco, San Francisco, CA 94121, USA
    Schizophr Bull 34:904-6. 2008
    ..These papers illustrate approaches to translational neuroscience that will increase our understanding of schizophrenia and provide neurobiological endpoints for developing novel treatments...
  31. ncbi request reprint Response-monitoring dysfunction in schizophrenia: an event-related brain potential study
    Daniel H Mathalon
    Department of Psychiatry, Yale University School of Medicine and Psychiatry Service and Veterans Affairs Healthcare System, West Haven, Connecticut, USA
    J Abnorm Psychol 111:22-41. 2002
    ..Despite ERN/CRN abnormalities, post-error slowing and Pe were normal in patients, suggesting a dissociation of ERN and error awareness. Anterior cingulate and dorsolateral prefrontal cortical dysfunction in schizophrenia are implicated...
  32. pmc Action planning and predictive coding when speaking
    Jun Wang
    Department of Psychiatry, University of Texas Southwestern, Dallas, TX 75390, USA
    Neuroimage 91:91-8. 2014
    ....
  33. pmc Schizophrenia, myelination, and delayed corollary discharges: a hypothesis
    Thomas J Whitford
    Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women s Hospital, Harvard Medical School, 1249 Boylston Street, Boston, MA 02215, USA
    Schizophr Bull 38:486-94. 2012
    ..The article concludes with a discussion of the implications of the theory and some testable predictions which may form a worthwhile basis for future research...
  34. ncbi request reprint Studying Hallucinations Within the NIMH RDoC Framework
    Judith M Ford
    San Francisco VA Medical Center, San Francisco, CA Department of Psychiatry, University of California, San Francisco, CA
    Schizophr Bull 40:S295-304. 2014
    ..We end with a discussion of various challenges and potential next steps to advance the application of the RDoC approach to this area of research. ..
  35. pmc Did I do that? Abnormal predictive processes in schizophrenia when button pressing to deliver a tone
    Judith M Ford
    Mental Health Service, San Francisco VA Medical Center, San Francisco, CA Department of Psychiatry, University of California, San Francisco, CA
    Schizophr Bull 40:804-12. 2014
    ..Effects seen during vocalization largely extend to other motor acts more translatable to lab animals. ..
  36. ncbi request reprint Brain regions associated with psychological pain: implications for a neural network and its relationship to physical pain
    Esther L Meerwijk
    Department of Community Health Systems, University of California, San Francisco, San Francisco, CA, USA
    Brain Imaging Behav 7:1-14. 2013
    ..Thus, identification of brain areas involved in psychological pain may help guide development of interventions to decrease mortality and morbidity...
  37. pmc Neurophysiological Distinction between Schizophrenia and Schizoaffective Disorder
    Daniel H Mathalon
    Psychiatry Service, San Francisco VA Medical Center and Department of Psychiatry, University of California San Francisco, CA, USA
    Front Hum Neurosci 3:70. 2010
    ..Although both groups show similar deficits in processing speed, SA patients do not exhibit the P300 amplitude deficits evident in SZ, consistent with an underlying pathophysiological boundary between these disorders...
  38. ncbi request reprint Functional neuroimaging and electrophysiology biomarkers for clinical trials for cognition in schizophrenia
    Raymond Y Cho
    Department of Psychiatry, University of Pittsburg School of Medicine, PA 15213, USA
    Schizophr Bull 31:865-9. 2005
    ....
  39. pmc Neurobiology of schizophrenia: search for the elusive correlation with symptoms
    Daniel H Mathalon
    Psychiatry Service, San Francisco VA Medical Center San Francisco, CA, USA
    Front Hum Neurosci 6:136. 2012
    ..We conclude with recommendations to promote progress in establishing brain-symptom relationships...
  40. pmc Divergent approaches converge on frontal lobe dysfunction in schizophrenia
    Daniel H Mathalon
    Am J Psychiatry 165:944-8. 2008
  41. ncbi request reprint Relationship of imprecise corollary discharge in schizophrenia to auditory hallucinations
    Theda H Heinks-Maldonado
    Department of Neuropsychology, Albert Ludwigs Universitat, Freiburg, Germany
    Arch Gen Psychiatry 64:286-96. 2007
    ..Imprecision of the corollary discharge in schizophrenia may contribute to the misperception of inner experiences and thoughts as "voices" or auditory hallucinations...
  42. ncbi request reprint Reduced communication between frontal and temporal lobes during talking in schizophrenia
    Judith M Ford
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305 5550, USA
    Biol Psychiatry 51:485-92. 2002
    ..Its dysfunction may underlie failure to recognize inner speech as self-generated and account for auditory hallucinations in schizophrenia...
  43. ncbi request reprint Acquiring and inhibiting prepotent responses in schizophrenia: event-related brain potentials and functional magnetic resonance imaging
    Judith M Ford
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, Calif 94305 5550, USA
    Arch Gen Psychiatry 61:119-29. 2004
    ..Schizophrenia is associated with deficits in using context to establish prepotent responses in complex paradigms and failures to inhibit prepotent responses once established...
  44. ncbi request reprint Are impairments of action monitoring and executive control true dissociative dysfunctions in patients with schizophrenia?
    And U Turken
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, CA 94305 5550, USA
    Am J Psychiatry 160:1881-3. 2003
    ..Impaired self-monitoring is considered a critical deficit of schizophrenia. The authors asked whether this is a specific and isolable impairment or is part of a global disturbance of cognitive and attentional functions...
  45. ncbi request reprint Fine-tuning of auditory cortex during speech production
    Theda H Heinks-Maldonado
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA
    Psychophysiology 42:180-90. 2005
    ..This is consistent with the operation of a precise forward model modulating the auditory cortical response to self-generated speech and allowing immediate distinction of self and externally generated auditory stimuli...
  46. ncbi request reprint Electrophysiological evidence of corollary discharge dysfunction in schizophrenia during talking and thinking
    Judith M Ford
    Department of Psychiatry and Behavioral Sciences Stanford University School of Medicine, and Psychiatry Service, Veterans Affairs Medical Center, Palo Alto, USA
    J Psychiatr Res 38:37-46. 2004
    ....
  47. ncbi request reprint Population pharmacokinetics of motexafin gadolinium in adults with brain metastases or glioblastoma multiforme
    Dale R Miles
    Pharmacyclics Inc, 995 E Arques Avenue, Sunnyvale, CA 94085, USA
    J Clin Pharmacol 45:299-312. 2005
    ..It was concluded that a 3-compartment, open, POP-PK model predicts small but significant effects of age, sex, alkaline phosphatase, hemoglobin, serum creatinine, and phenytoin on MGd pharmacokinetics...

Research Grants2

  1. Auditory Hallucinations in Schizophrenia: ERPs & fMRI
    Handan Gunduz Bruce; Fiscal Year: 2005
    ..abstract_text> ..
  2. Neurobiology of Response Failure in Schizophrenia
    Judith Ford; Fiscal Year: 2007
    ....