Tanya Z Fischer

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi request reprint Extraterritorial temperature pain threshold abnormalities in subjects with healed thermal injury
    Tanya Z Fischer
    Department of Neurology, Yale University School of Medicine, New Haven, CT, USA
    J Rehabil Res Dev 49:515-22. 2012
  2. doi request reprint Thalamic neuron hyperexcitability and enlarged receptive fields in the STZ model of diabetic pain
    Tanya Z Fischer
    Department of Neurology, Yale University School of Medicine, New Haven, CT 06510, USA
    Brain Res 1268:154-61. 2009
  3. doi request reprint Familial pain syndromes from mutations of the NaV1.7 sodium channel
    Tanya Z Fischer
    Department of Neurology, Yale University School of Medicine, New Haven, Connecticut, USA
    Ann N Y Acad Sci 1184:196-207. 2010
  4. pmc Mutations at opposite ends of the DIII/S4-S5 linker of sodium channel Na V 1.7 produce distinct pain disorders
    Xiaoyang Cheng
    Department of Neurology and Center for Neuroscience and Regeneration Research, Yale University School of Medicine, New Haven, CT, USA
    Mol Pain 6:24. 2010
  5. ncbi request reprint A novel Nav1.7 mutation producing carbamazepine-responsive erythromelalgia
    Tanya Z Fischer
    Department of Neurology, Yale University School of Medicine, New Haven, CT 16510, USA
    Ann Neurol 65:733-41. 2009
  6. doi request reprint Maladaptive dendritic spine remodeling contributes to diabetic neuropathic pain
    Andrew M Tan
    Department of Neurology and Center for Neuroscience and Regeneration Research, Yale University School of Medicine, New Haven, Connecticut 06510, USA
    J Neurosci 32:6795-807. 2012
  7. pmc Paroxysmal extreme pain disorder M1627K mutation in human Nav1.7 renders DRG neurons hyperexcitable
    Sulayman D Dib-Hajj
    Deptartment of Neurology, Yale University School of Medicine, New Haven, CT 06510, USA
    Mol Pain 4:37. 2008
  8. pmc Sodium-calcium exchanger and multiple sodium channel isoforms in intra-epidermal nerve terminals
    Anna Karin Persson
    Department of Neurology and Center for Neuroscience and Regeneration Research, Yale University School of Medicine, New Haven, CT 06510, USA
    Mol Pain 6:84. 2010
  9. doi request reprint Neuropathic pain in diabetes--evidence for a central mechanism
    Tanya Z Fischer
    Yale University Center for Neuroscience and Regeneration Research, Veterans Affairs Connecticut Healthcare System, 950 Campbell Avenue, West Haven, CT 06516, USA
    Nat Rev Neurol 6:462-6. 2010

Detail Information

Publications9

  1. ncbi request reprint Extraterritorial temperature pain threshold abnormalities in subjects with healed thermal injury
    Tanya Z Fischer
    Department of Neurology, Yale University School of Medicine, New Haven, CT, USA
    J Rehabil Res Dev 49:515-22. 2012
    ....
  2. doi request reprint Thalamic neuron hyperexcitability and enlarged receptive fields in the STZ model of diabetic pain
    Tanya Z Fischer
    Department of Neurology, Yale University School of Medicine, New Haven, CT 06510, USA
    Brain Res 1268:154-61. 2009
    ..These results suggest that aberrant levels of spontaneous activity and hyper-responsiveness of VPL thalamic neurons may contribute to diabetic neuropathic pain...
  3. doi request reprint Familial pain syndromes from mutations of the NaV1.7 sodium channel
    Tanya Z Fischer
    Department of Neurology, Yale University School of Medicine, New Haven, Connecticut, USA
    Ann N Y Acad Sci 1184:196-207. 2010
    ..7 channel may provide a unique target for the pharmacotherapy of pain in humans. In this review article we summarize current knowledge regarding several different disease manifestations arising from changes within the Na(v)1.7 channel...
  4. pmc Mutations at opposite ends of the DIII/S4-S5 linker of sodium channel Na V 1.7 produce distinct pain disorders
    Xiaoyang Cheng
    Department of Neurology and Center for Neuroscience and Regeneration Research, Yale University School of Medicine, New Haven, CT, USA
    Mol Pain 6:24. 2010
    ....
  5. ncbi request reprint A novel Nav1.7 mutation producing carbamazepine-responsive erythromelalgia
    Tanya Z Fischer
    Department of Neurology, Yale University School of Medicine, New Haven, CT 16510, USA
    Ann Neurol 65:733-41. 2009
    ..Inherited erythromelalgia (IEM) has been linked to gain-of-function mutations of Na(v)1.7. We now report a novel mutation (V400M) in a three-generation Canadian family in which pain is relieved by carbamazepine (CBZ)...
  6. doi request reprint Maladaptive dendritic spine remodeling contributes to diabetic neuropathic pain
    Andrew M Tan
    Department of Neurology and Center for Neuroscience and Regeneration Research, Yale University School of Medicine, New Haven, Connecticut 06510, USA
    J Neurosci 32:6795-807. 2012
    ..Molecular pathways that control spine morphogenesis and plasticity may be promising future targets for treatment...
  7. pmc Paroxysmal extreme pain disorder M1627K mutation in human Nav1.7 renders DRG neurons hyperexcitable
    Sulayman D Dib-Hajj
    Deptartment of Neurology, Yale University School of Medicine, New Haven, CT 06510, USA
    Mol Pain 4:37. 2008
    ..Carbamazepine has been effective in relieving symptoms, while other drugs including other anti-epileptics are less effective...
  8. pmc Sodium-calcium exchanger and multiple sodium channel isoforms in intra-epidermal nerve terminals
    Anna Karin Persson
    Department of Neurology and Center for Neuroscience and Regeneration Research, Yale University School of Medicine, New Haven, CT 06510, USA
    Mol Pain 6:84. 2010
    ..In this study, we examined the expression and distribution of Na+/Ca2+ exchanger (NCX) and voltage-gated sodium channel isoforms in intra-epidermal free nerve terminals...
  9. doi request reprint Neuropathic pain in diabetes--evidence for a central mechanism
    Tanya Z Fischer
    Yale University Center for Neuroscience and Regeneration Research, Veterans Affairs Connecticut Healthcare System, 950 Campbell Avenue, West Haven, CT 06516, USA
    Nat Rev Neurol 6:462-6. 2010
    ..In this article, we discuss these findings, which suggest that thalamic neurons can act as central generators or amplifiers of pain in diabetes...