A S Fanning

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi Localization of the tight junction protein gene TJP1 to human chromosome 15q13, distal to the Prader-Willi/Angelman region, and to mouse chromosome 7
    T K Mohandas
    Department of Pathology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
    Genomics 30:594-7. 1995
  2. ncbi The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton
    A S Fanning
    Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut 06510, USA
    J Biol Chem 273:29745-53. 1998
  3. pmc PDZ domains: fundamental building blocks in the organization of protein complexes at the plasma membrane
    A S Fanning
    Departments of Internal Medicine and Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06520 8019, USA
    J Clin Invest 103:767-72. 1999
  4. ncbi Protein modules as organizers of membrane structure
    A S Fanning
    Departments of Internal Medicine and Cell Biology, Yale University School of Medicine, PO Box 208019, New Haven, CT 06520 8019, USA
    Curr Opin Cell Biol 11:432-9. 1999
  5. pmc The tight junction protein ZO-1 is homologous to the Drosophila discs-large tumor suppressor protein of septate junctions
    E Willott
    Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06510
    Proc Natl Acad Sci U S A 90:7834-8. 1993
  6. pmc Connexin-occludin chimeras containing the ZO-binding domain of occludin localize at MDCK tight junctions and NRK cell contacts
    L L Mitic
    Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Cell Biol 146:683-93. 1999
  7. ncbi Differential regulation of skeletal muscle myosin-II and brush border myosin-I enzymology and mechanochemistry by bacterially produced tropomyosin isoforms
    A S Fanning
    Department of Genetics, Yale University School of Medicine, New Haven, Connecticut 06521 8019
    Cell Motil Cytoskeleton 29:29-45. 1994

Collaborators

Detail Information

Publications7

  1. ncbi Localization of the tight junction protein gene TJP1 to human chromosome 15q13, distal to the Prader-Willi/Angelman region, and to mouse chromosome 7
    T K Mohandas
    Department of Pathology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
    Genomics 30:594-7. 1995
    ..FISH studies on metaphases from patients with the Prader-Willi (PWS) or the Angelman syndrome (AS) showed that TJP1 maps close but distal to the PWS/AS chromosome region...
  2. ncbi The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton
    A S Fanning
    Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut 06510, USA
    J Biol Chem 273:29745-53. 1998
    ..These observations suggest that one functional role of ZO-1 is to organize components of the tight junction and link them to the cortical actin cytoskeleton...
  3. pmc PDZ domains: fundamental building blocks in the organization of protein complexes at the plasma membrane
    A S Fanning
    Departments of Internal Medicine and Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06520 8019, USA
    J Clin Invest 103:767-72. 1999
  4. ncbi Protein modules as organizers of membrane structure
    A S Fanning
    Departments of Internal Medicine and Cell Biology, Yale University School of Medicine, PO Box 208019, New Haven, CT 06520 8019, USA
    Curr Opin Cell Biol 11:432-9. 1999
    ..The organization of these proteins into discreet structures has functional consequences for downstream signaling...
  5. pmc The tight junction protein ZO-1 is homologous to the Drosophila discs-large tumor suppressor protein of septate junctions
    E Willott
    Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06510
    Proc Natl Acad Sci U S A 90:7834-8. 1993
    ..The C-terminal domain of ZO-1, and its alternatively spliced region, appears to confer variable properties unique to tight junctions...
  6. pmc Connexin-occludin chimeras containing the ZO-binding domain of occludin localize at MDCK tight junctions and NRK cell contacts
    L L Mitic
    Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Cell Biol 146:683-93. 1999
    ..Such a scaffolding and cytoskeletal coupling function for ZO MAGUKs is analogous to that of other members of the MAGUK family...
  7. ncbi Differential regulation of skeletal muscle myosin-II and brush border myosin-I enzymology and mechanochemistry by bacterially produced tropomyosin isoforms
    A S Fanning
    Department of Genetics, Yale University School of Medicine, New Haven, Connecticut 06521 8019
    Cell Motil Cytoskeleton 29:29-45. 1994
    ..These results demonstrate that bacterially produced tropomyosins can differentially regulate myosin enzymology and mechanochemistry, and suggest a role for tropomyosin in the coordinated regulation of myosin isoforms in vivo...