Research Topics
| Damien A FairSummaryAffiliation: Yale University Country: USA Publications
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Detail Information
Publications
The maturing architecture of the brain's default networkDamien A Fair
Department of Neurology, Washington University, St Louis, MO 63110, USA
Proc Natl Acad Sci U S A 105:4028-32. 2008..We found that the default regions are only sparsely functionally connected at early school age (7-9 years old); over development, these regions integrate into a cohesive, interconnected network...- Distinct neuropsychological subgroups in typically developing youth inform heterogeneity in children with ADHDDamien A Fair
Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR 97239, USA
Proc Natl Acad Sci U S A 109:6769-74. 2012..The second tenet proposes that some of the heterogeneity in individuals with ADHD might be "nested" in this normal variation... - Atypical default network connectivity in youth with attention-deficit/hyperactivity disorderDamien A Fair
Department of Psychiatry, Oregon Health and Science University, Portland, 97239, USA
Biol Psychiatry 68:1084-91. 2010..Thus, the pathophysiology of ADHD might include delayed or disrupted maturation of the default network. If so, it is important to determine whether an altered developmental picture can be detected using rs-fcMRI in children with ADHD... - Functional brain networks develop from a "local to distributed" organizationDamien A Fair
Behavioral Neuroscience Department, Oregon Health and Science University, Portland, OR, USA
PLoS Comput Biol 5:e1000381. 2009..These observations suggest that early school age children and adults both have relatively efficient systems that may solve similar information processing problems in divergent ways... - The functional organization of trial-related activity in lexical processing after early left hemispheric brain lesions: An event-related fMRI studyDamien A Fair
Department of Psychiatry, Oregon Health and Science University, Portland, 97239, United States
Brain Lang 114:135-46. 2010..In addition, reported differences between results obtained with event-related designs and blocked designs may suggest diverging organizing principles for sustained and trial-related activity after early childhood brain injuries... - Control networks in paediatric Tourette syndrome show immature and anomalous patterns of functional connectivityJessica A Church
Department of Neurology, Washington University School of Medicine, St Louis, MS 63110, USA
Brain 132:225-38. 2009..These results suggest that in adolescents with TS, immature functional connectivity is widespread, with additional, more profound deviation of connectivity in regions related to adaptive online control... - Prediction of individual brain maturity using fMRINico U F Dosenbach
Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
Science 329:1358-61. 2010..The greatest relative contribution to predicting individual brain maturity was made by the weakening of short-range functional connections between the adult brain's major functional networks... - A method for using blocked and event-related fMRI data to study "resting state" functional connectivityDamien A Fair
Department of Neurology, Washington University School of Medicine, Campus Box 8111, 660 S Euclid, St Louis, MO 63110, USA
Neuroimage 35:396-405. 2007..Although using event-related data residuals for resting state functional connectivity may still be useful, results should be interpreted with care... - Distinct brain networks for adaptive and stable task control in humansNico U F Dosenbach
Department of Radiology, Washington University, St Louis, MO 63110, USA
Proc Natl Acad Sci U S A 104:11073-8. 2007..These two independent networks appear to operate on different time scales and affect downstream processing via dissociable mechanisms... - Defining functional areas in individual human brains using resting functional connectivity MRIAlexander L Cohen
Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
Neuroimage 41:45-57. 2008..Our approach reliably produces maps of bounded regions appropriate in size and number for putative functional areas. These findings will hopefully stimulate further methodological refinements and validations... - Development of distinct control networks through segregation and integrationDamien A Fair
Departments of Neurology, Washington University, St Louis, MO 63110, USA
Proc Natl Acad Sci U S A 104:13507-12. 2007..Delay/disruption in the developmental processes of segregation and integration may play a role in disorders of control, such as autism, attention deficit hyperactivity disorder, and Tourette's syndrome... - Premotor functional connectivity predicts impulsivity in juvenile offendersBenjamin J Shannon
Department of Radiology, Washington University, St Louis, MO 63110, USA
Proc Natl Acad Sci U S A 108:11241-5. 2011..This observation suggests that impulsivity in the offender population is a consequence of a delay in typical development, rather than a distinct abnormality... - The development of human functional brain networksJonathan D Power
Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
Neuron 67:735-48. 2010.... - Maturing thalamocortical functional connectivity across developmentDamien A Fair
Department of Psychiatry, Oregon Health and Science University Portland, OR, USA
Front Syst Neurosci 4:10. 2010..The methods and developmental context provided here will be important for understanding how cortical-subcortical interactions relate to models of typically developing behavior and developmental neuropsychiatric disorders... 
A dual-networks architecture of top-down controlNico U F Dosenbach
Washington University in St Louis School of Medicine, 4525 Scott Ave, St Louis, MO 63110, USA
Trends Cogn Sci 12:99-105. 2008..The control systems of the brain seem to embody the principles of complex systems, encouraging resilient performance...- Reward circuit connectivity relates to delay discounting in children with attention-deficit/hyperactivity disorderTaciana G Costa Dias
Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, OR, USA
Eur Neuropsychopharmacol 23:33-45. 2013..These findings are consistent with the hypothesis that atypical signaling of the NAcc to the prefrontal cortex in ADHD may lead to excessive approach and failure in estimating future consequences; thus, leading to impulsive behavior... - Distinct neural signatures detected for ADHD subtypes after controlling for micro-movements in resting state functional connectivity MRI dataDamien A Fair
Department of Behavioral Neuroscience, Advanced Imaging Research Center, Oregon Health and Science University Portland, OR, USA Department of Psychiatry, Advanced Imaging Research Center, Oregon Health and Science University Portland, OR, USA
Front Syst Neurosci 6:80. 2012..These data suggest that resting-state functional connectivity MRI (rs-fcMRI) data can be used to characterize individual patients with ADHD and to identify neural distinctions underlying the clinical heterogeneity of ADHD... - Task-evoked BOLD responses are normal in areas of diaschisis after strokeDamien A Fair
Department of Neurology, Washington University School of Medicine, St Louis, Missouri 63110, USA
Neurorehabil Neural Repair 23:52-7. 2009..Although the functional magnetic resonance imaging (fMRI) blood oxygen level dependent (BOLD) signal is increasingly used to examine the neural correlates of recovery in stroke, its reliability in areas of diaschisis is uncertain... 
fMRI reveals novel functional neuroanatomy in a child with perinatal strokeDamien A Fair
PA C, Department of Neurology, Campus Box 8111, Washington University School of Medicine, 660 S Euclid Avenue, St Louis, MO 63110, USA
Neurology 67:2246-9. 2006..Although the data for this child are similar to the control group, there are age-dependent differences...- A comparison of analysis of variance and correlation methods for investigating cognitive development with functional magnetic resonance imagingDamien A Fair
Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
Dev Neuropsychol 30:531-46. 2006..These findings suggest that full characterization of developmental dynamics will require converging methodologies... - Altered cortico-striatal-thalamic connectivity in relation to spatial working memory capacity in children with ADHDKathryn L Mills
Department of Behavioral Neuroscience, Oregon Health and Science University Portland, OR, USA
Front Psychiatry 3:2. 2012..These thalamo-striatal disruptions may be one of multiple atypical neural and cognitive mechanisms that relate to the ADHD clinical phenotype... - Functional brain network modularity captures inter- and intra-individual variation in working memory capacityAlexander A Stevens
Department of Psychiatry, Oregon Health and Science University, Portland, Oregon, United States of America
PLoS ONE 7:e30468. 2012..Here we specifically examine how changes in the organization of large-scale networks measured via resting state functional connectivity MRI and graph theory track changes in working memory capacity...