Enric Esplugues

Summary

Affiliation: Yale University
Country: USA

Publications

  1. pmc Control of TH17 cells occurs in the small intestine
    Enric Esplugues
    Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Nature 475:514-8. 2011
  2. pmc Th17 cells express interleukin-10 receptor and are controlled by Foxp3⁻ and Foxp3+ regulatory CD4+ T cells in an interleukin-10-dependent manner
    Samuel Huber
    Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA
    Immunity 34:554-65. 2011
  3. pmc Oct-1 regulates IL-17 expression by directing interchromosomal associations in conjunction with CTCF in T cells
    Lark Kyun Kim
    Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06520, USA
    Mol Cell 54:56-66. 2014

Detail Information

Publications3

  1. pmc Control of TH17 cells occurs in the small intestine
    Enric Esplugues
    Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Nature 475:514-8. 2011
    ..These results identify mechanisms limiting T(H)17 cell pathogenicity and implicate the gastrointestinal tract as a site for control of T(H)17 cells...
  2. pmc Th17 cells express interleukin-10 receptor and are controlled by Foxp3⁻ and Foxp3+ regulatory CD4+ T cells in an interleukin-10-dependent manner
    Samuel Huber
    Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA
    Immunity 34:554-65. 2011
    ..Lastly, IL-10 treatment of mice with established colitis decreased Th17 and Th17+Th1 cell frequencies via direct signaling in T cells. Thus, IL-10 signaling directly suppresses Th17 and Th17+Th1 cells...
  3. pmc Oct-1 regulates IL-17 expression by directing interchromosomal associations in conjunction with CTCF in T cells
    Lark Kyun Kim
    Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06520, USA
    Mol Cell 54:56-66. 2014
    ..Finally, defects in the association lead to enhanced IL-17 induction. Collectively, our data indicate Th17 lineage differentiation is restrained by the Th2 locus via interchromosomal associations organized by Oct-1 and CTCF. ..