R A Ehrenkranz

Summary

Affiliation: Yale University
Country: USA

Publications

  1. doi request reprint Ongoing issues in the intensive care for the periviable infant--nutritional management and prevention of bronchopulmonary dysplasia and nosocomial infections
    Richard A Ehrenkranz
    Department of Pediatrics and Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, PO Box 208064, New Haven, CT 06520 8064 Electronic address
    Semin Perinatol 38:25-30. 2014
  2. pmc Inhaled nitric oxide in preterm infants: a systematic review and individual patient data meta-analysis
    Lisa M Askie
    NHMRC Clinical Trials Centre, University of Sydney, Australia
    BMC Pediatr 10:15. 2010
  3. ncbi request reprint NICHD neonatal research network: contributions and future challenges
    Richard A Ehrenkranz
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520 8064, USA
    Semin Perinatol 27:264-80. 2003
  4. ncbi request reprint Growth in the neonatal intensive care unit influences neurodevelopmental and growth outcomes of extremely low birth weight infants
    Richard A Ehrenkranz
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520 8064, USA
    Pediatrics 117:1253-61. 2006
  5. pmc Estimated fetal weights versus birth weights: should the reference intrauterine growth curves based on birth weights be retired?
    Richard A Ehrenkranz
    Yale University School of Medicine, 333 Cedar Street, PO Box 208064, New Haven, CT 06520 8064
    Arch Dis Child Fetal Neonatal Ed 92:F161-2. 2007
  6. ncbi request reprint Early, aggressive nutritional management for very low birth weight infants: what is the evidence?
    Richard A Ehrenkranz
    Department of Pediatrics and Obstetrics and Gynecology, Yale University School of Medicine, New Haven, CT 06520 8064, USA
    Semin Perinatol 31:48-55. 2007
  7. doi request reprint Early nutritional support and outcomes in ELBW infants
    Richard A Ehrenkranz
    Department of Pediatrics, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA
    Early Hum Dev 86:21-5. 2010
  8. ncbi request reprint Validation of the National Institutes of Health consensus definition of bronchopulmonary dysplasia
    Richard A Ehrenkranz
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520 8064, USA
    Pediatrics 116:1353-60. 2005
  9. ncbi request reprint Longitudinal growth of hospitalized very low birth weight infants
    R A Ehrenkranz
    Yale University, New Haven, Connecticut, USA
    Pediatrics 104:280-9. 1999
  10. ncbi request reprint Growth outcomes of very low-birth weight infants in the newborn intensive care unit
    R A Ehrenkranz
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA
    Clin Perinatol 27:325-45. 2000

Research Grants

  1. NICHD Cooperative Multicenter Neonatal Research Network
    Richard Ehrenkranz; Fiscal Year: 2006
  2. NICHD Cooperative Multicenter Neonatal Research Network
    Richard Ehrenkranz; Fiscal Year: 2007

Collaborators

Detail Information

Publications51

  1. doi request reprint Ongoing issues in the intensive care for the periviable infant--nutritional management and prevention of bronchopulmonary dysplasia and nosocomial infections
    Richard A Ehrenkranz
    Department of Pediatrics and Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, PO Box 208064, New Haven, CT 06520 8064 Electronic address
    Semin Perinatol 38:25-30. 2014
    ....
  2. pmc Inhaled nitric oxide in preterm infants: a systematic review and individual patient data meta-analysis
    Lisa M Askie
    NHMRC Clinical Trials Centre, University of Sydney, Australia
    BMC Pediatr 10:15. 2010
    ....
  3. ncbi request reprint NICHD neonatal research network: contributions and future challenges
    Richard A Ehrenkranz
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520 8064, USA
    Semin Perinatol 27:264-80. 2003
    ....
  4. ncbi request reprint Growth in the neonatal intensive care unit influences neurodevelopmental and growth outcomes of extremely low birth weight infants
    Richard A Ehrenkranz
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520 8064, USA
    Pediatrics 117:1253-61. 2006
    ....
  5. pmc Estimated fetal weights versus birth weights: should the reference intrauterine growth curves based on birth weights be retired?
    Richard A Ehrenkranz
    Yale University School of Medicine, 333 Cedar Street, PO Box 208064, New Haven, CT 06520 8064
    Arch Dis Child Fetal Neonatal Ed 92:F161-2. 2007
  6. ncbi request reprint Early, aggressive nutritional management for very low birth weight infants: what is the evidence?
    Richard A Ehrenkranz
    Department of Pediatrics and Obstetrics and Gynecology, Yale University School of Medicine, New Haven, CT 06520 8064, USA
    Semin Perinatol 31:48-55. 2007
    ..It is important that neonatal clinicians recognize the barriers and obstacles to the implementation of these recommendations...
  7. doi request reprint Early nutritional support and outcomes in ELBW infants
    Richard A Ehrenkranz
    Department of Pediatrics, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA
    Early Hum Dev 86:21-5. 2010
    ..This paper will review the evidence supporting the provision of early nutritional support to extremely preterm infants by examining the outcomes associated with such practices...
  8. ncbi request reprint Validation of the National Institutes of Health consensus definition of bronchopulmonary dysplasia
    Richard A Ehrenkranz
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520 8064, USA
    Pediatrics 116:1353-60. 2005
    ..The objective of this study was to determine the predictive validity of the severity-based, consensus definition of BPD...
  9. ncbi request reprint Longitudinal growth of hospitalized very low birth weight infants
    R A Ehrenkranz
    Yale University, New Haven, Connecticut, USA
    Pediatrics 104:280-9. 1999
    ..The interpretation of growth rates for very low birth weight infants is obscured by limited data, recent changes in perinatal care, and the uncertain effects of multiple therapies...
  10. ncbi request reprint Growth outcomes of very low-birth weight infants in the newborn intensive care unit
    R A Ehrenkranz
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA
    Clin Perinatol 27:325-45. 2000
    ..Longitudinal growth curves of hospitalized VLBW infants, such as the ones described in this article, should not be considered optimal and should be updated as ways safely to improve the growth of VLBW infants are identified...
  11. pmc Early nutrition mediates the influence of severity of illness on extremely LBW infants
    Richard A Ehrenkranz
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Pediatr Res 69:522-9. 2011
    ....
  12. pmc Sex differences in outcomes of very low birthweight infants: the newborn male disadvantage
    D K Stevenson
    Department of Pediatrics, Stanford University, Palo Alto, CA 94305 5119, USA
    Arch Dis Child Fetal Neonatal Ed 83:F182-5. 2000
    ..To determine the differences in short term outcome of very low birthweight infants attributable to sex...
  13. doi request reprint Clinical parameters do not adequately predict outcome in necrotizing enterocolitis: a multi-institutional study
    R L Moss
    Department of Surgery, Yale University School of Medicine, New Haven, CT 06520, USA
    J Perinatol 28:665-74. 2008
    ..We hypothesized that comprehensive prospective data collection at multiple centers would allow us to develop a model which would identify those babies at risk for progressive NEC...
  14. ncbi request reprint Recombinant human erythropoietin stimulates erythropoiesis and reduces erythrocyte transfusions in very low birth weight preterm infants
    K M Shannon
    Department of Pediatrics, University of California, San Francisco 94143 0724, USA
    Pediatrics 95:1-8. 1995
    ..All patients received oral iron and were managed according to uniform conservative transfusion guidelines...
  15. ncbi request reprint A randomized controlled trial of synchronized nasal intermittent positive pressure ventilation in RDS
    V Bhandari
    Department of Pediatrics, Albert Einstein Medical Center, Philadelphia, PA, USA
    J Perinatol 27:697-703. 2007
    ..Comparison of outcomes of infants with respiratory distress syndrome (RDS), post-surfactant, extubated to synchronized nasal intermittent positive pressure ventilation (SNIPPV) or continued on conventional ventilation (CV)...
  16. ncbi request reprint Changes in arterial oxygen tension when weaning neonates from inhaled nitric oxide
    G M Sokol
    Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana 46202 5271, USA
    Pediatr Pulmonol 32:14-9. 2001
    ..51). In conclusion, a graded decline in PaO(2) occurs when reducing INO. INO should be weaned to less than 1 ppm before discontinuing its use. Prior surfactant treatment appears to enhance the oxygenation reserve when weaning INO...
  17. ncbi request reprint Randomized trial of enteral protein and energy supplementation in infants less than or equal to 1250 g at birth
    H L Brumberg
    Division of Newborn Medicine, Department of Pediatrics, New York Medical College, Maria Fareri Children s Hospital, Westchester Medical Center, Valhalla, NY 10595, USA
    J Perinatol 30:517-21. 2010
    ..To determine if enteral protein and energy supplementation would significantly improve weight gain as compared with energy supplementation alone in <or=1250 g infants...
  18. pmc Predictors of death or bronchopulmonary dysplasia in preterm infants with respiratory failure
    N Ambalavanan
    Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35249, USA
    J Perinatol 28:420-6. 2008
    ..To identify the variables that predict death/physiologic bronchopulmonary dysplasia (BPD) in preterm infants with severe respiratory failure...
  19. ncbi request reprint Neonatal auditory activation detected by functional magnetic resonance imaging
    A W Anderson
    Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT, USA
    Magn Reson Imaging 19:1-5. 2001
    ..In contrast, signal decreases were detected during auditory stimulation in 9 of 14 newborns with BOLD response. fMRI can be used to detect brain activation with auditory stimulation in human infants...
  20. ncbi request reprint Growth failure in the preterm infant: can we catch up?
    Anna M Dusick
    Section of Developmental Pediatrics, Indiana University School of Medicine, Indianapolis, IN 46202 5119, USA
    Semin Perinatol 27:302-10. 2003
    ..Additional trials are needed to address a number of important questions concerning the role of nutrition and growth on ultimate development...
  21. ncbi request reprint Parenteral nutrition-associated cholestasis in small for gestational age infants
    Daniel T Robinson
    Yale University School of Medicine, New Haven, Connecticut, USA
    J Pediatr 152:59-62. 2008
    ..To identify small for gestational age (SGA) as an independent risk factor for parenteral nutrition-associated cholestasis (PNAC)...
  22. ncbi request reprint Risk factors for early death among extremely low-birth-weight infants
    Seetha Shankaran
    Wayne State University, Detroit, Michigan, USA
    Am J Obstet Gynecol 186:796-802. 2002
    ....
  23. pmc Neurodevelopmental outcomes of premature infants with severe respiratory failure enrolled in a randomized controlled trial of inhaled nitric oxide
    Susan R Hintz
    NICHD Neonatal Research Network
    J Pediatr 151:16-22, 22.e1-3. 2007
    ....
  24. pmc Community supports after surviving extremely low-birth-weight, extremely preterm birth: special outpatient services in early childhood
    Susan R Hintz
    Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, California 94304, USA
    Arch Pediatr Adolesc Med 162:748-55. 2008
    ..To determine special outpatient services (SOS) use, need, associated factors, and neurodevelopmental and functional outcomes among extremely preterm infants at 18 to 22 months' corrected age...
  25. pmc Very low birth weight preterm infants with surgical short bowel syndrome: incidence, morbidity and mortality, and growth outcomes at 18 to 22 months
    Conrad R Cole
    Emory University School of Medicine, Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, 2015 Uppergate Dr, Atlanta, GA 30322, USA
    Pediatrics 122:e573-82. 2008
    ....
  26. pmc Early inhaled nitric oxide therapy for term and near-term newborn infants with hypoxic respiratory failure: neurodevelopmental follow-up
    G Ganesh Konduri
    Medical College of WI, Dept of Pediatrics and the Children s Research Institute, Milwaukee, WI 53201 1997, USA
    J Pediatr 150:235-40, 240.e1. 2007
    ..To report the neurodevelopmental outcome of infants enrolled in a randomized multicenter trial of early inhaled nitric oxide (iNO) in term and near-term neonates with hypoxic respiratory failure and pulmonary hypertension...
  27. ncbi request reprint Effect of introduction of synchronized nasal intermittent positive-pressure ventilation in a neonatal intensive care unit on bronchopulmonary dysplasia and growth in preterm infants
    Ameya Kulkarni
    Division of Perinatal Medicine, Department of Pediatrics, Yale New Haven Children s Hospital, New Haven, Connecticut 06520 8064, USA
    Am J Perinatol 23:233-40. 2006
    ....
  28. ncbi request reprint Early provision of parenteral amino acids in extremely low birth weight infants: relation to growth and neurodevelopmental outcome
    Brenda B Poindexter
    Department of Pediatrics, Indiana University School of Medicine, Indianapolis, 46202, USA
    J Pediatr 148:300-305. 2006
    ..To determine if postnatal growth failure exerts an adverse effect on subsequent growth and neurodevelopment...
  29. ncbi request reprint Late-onset sepsis in very low birth weight neonates: the experience of the NICHD Neonatal Research Network
    Barbara J Stoll
    Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Pediatrics 110:285-91. 2002
    ....
  30. ncbi request reprint Neurodevelopmental outcome and growth at 18 to 22 months' corrected age in extremely low birth weight infants treated with early erythropoietin and iron
    Robin K Ohls
    Department of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA
    Pediatrics 114:1287-91. 2004
    ..Clinical trials evaluating the use of erythropoietin (Epo) have demonstrated a limited reduction in transfusions; however, long-term developmental follow-up data are scarce...
  31. ncbi request reprint Impact of postnatal systemic corticosteroids on mortality and cerebral palsy in preterm infants: effect modification by risk for chronic lung disease
    Lex W Doyle
    Division of Paediatrics, Royal Women s Hospital, 132 Grattan St, Carlton 3053, Australia
    Pediatrics 115:655-61. 2005
    ..The objective of this study was to determine the effect of systemic postnatal corticosteroid treatment on death and CP and to assess any modification of effect arising from risk for CLD...
  32. ncbi request reprint Inhaled nitric oxide for premature infants with severe respiratory failure
    Krisa P Van Meurs
    Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, Calif 94304, USA
    N Engl J Med 353:13-22. 2005
    ..We conducted a multicenter, randomized, blinded, controlled trial to determine whether inhaled nitric oxide reduced the rate of death or bronchopulmonary dysplasia in such infants...
  33. ncbi request reprint Neurodevelopmental outcome of premature infants after antenatal phenobarbital exposure
    Seetha Shankaran
    Wayne State University, Detroit, MI, USA
    Am J Obstet Gynecol 187:171-7. 2002
    ....
  34. ncbi request reprint Parenteral glutamine supplementation does not reduce the risk of mortality or late-onset sepsis in extremely low birth weight infants
    Brenda B Poindexter
    Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Pediatrics 113:1209-15. 2004
    ..Whether glutamine supplementation would provide a similar benefit to extremely low birth weight (ELBW) infants is not known...
  35. ncbi request reprint Changes in pathogens causing early-onset sepsis in very-low-birth-weight infants
    Barbara J Stoll
    Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA
    N Engl J Med 347:240-7. 2002
    ....
  36. ncbi request reprint Effect of parenteral glutamine supplementation on plasma amino acid concentrations in extremely low-birth-weight infants
    Brenda B Poindexter
    Indiana University, Indianapolis, USA
    Am J Clin Nutr 77:737-43. 2003
    ..Glutamine is one of the most abundant amino acids in both plasma and human milk and may be conditionally essential in premature infants. However, glutamine is not provided by standard intravenous amino acid solutions...
  37. ncbi request reprint Association between fluid intake and weight loss during the first ten days of life and risk of bronchopulmonary dysplasia in extremely low birth weight infants
    William Oh
    Neonatal Research Center, Bethesda, MD, USA
    J Pediatr 147:786-90. 2005
    ..To demonstrate the association between fluid intake and weight loss during the first 10 days of life and the risk of bronchopulmonary dysplasia (BPD) in extremely low birth weight (ELBW) infants...
  38. pmc Aggressive vs. conservative phototherapy for infants with extremely low birth weight
    Brenda H Morris
    University of Texas Medical School, Houston, TX 77030, USA
    N Engl J Med 359:1885-96. 2008
    ..It is unclear whether aggressive phototherapy to prevent neurotoxic effects of bilirubin benefits or harms infants with extremely low birth weight (1000 g or less)...
  39. pmc Association between urinary lactate to creatinine ratio and neurodevelopmental outcome in term infants with hypoxic-ischemic encephalopathy
    William Oh
    Department of Pediatrics, Warren Alpert Medical School of Brown University, Providence, RI, USA
    J Pediatr 153:375-8. 2008
    ..To assess the association between urinary lactate to creatinine ratio (ULCR) and neurodevelopmental outcome in term infants with hypoxic ischemic encephalopathy and examine the effect of hypothermia on the change in ULCR...
  40. pmc Neurodevelopmental outcome of extremely low birth weight infants with posthemorrhagic hydrocephalus requiring shunt insertion
    Ira Adams-Chapman
    Department of Pediatrics Division of Neonatology, Emory University School of Medicine, 46 Jesse Hill Jr Drive SE, Atlanta, GA 30303, USA
    Pediatrics 121:e1167-77. 2008
    ..We aimed to evaluate neurodevelopmental and growth outcomes among extremely low birth weight infants who had severe intraventricular hemorrhage that required shunt insertion compared with infants without shunt insertion...
  41. ncbi request reprint Somatic growth of preterm infants during skin-to-skin care versus traditional holding: a randomized, controlled trial
    Mario A Rojas
    Department of Pediatrics, Childre s Hospitak at Yale New Haven, Connecticut, USA
    J Dev Behav Pediatr 24:163-8. 2003
    ..However, exposure to SSC was associated with greater head growth, even after controlling for head circumference at birth (p =.03). SSC may increase the likelihood of successful breastfeeding...
  42. ncbi request reprint Extremely low birthweight neonates with protracted ventilation: mortality and 18-month neurodevelopmental outcomes
    Michele C Walsh
    Department of Pediatrics, Case Western Reserve University, Cleveland, Ohio, USA
    J Pediatr 146:798-804. 2005
    ..To compare duration of ventilation to mortality and adverse neurodevelopmental outcomes among extremely low birth weight (ELBW; 501-1000 g) infants...
  43. ncbi request reprint Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy
    Seetha Shankaran
    Division of Neonatal Perinatal Medicine, Wayne State University, Children s Hospital of Michigan, Detroit, MI 48201, USA
    N Engl J Med 353:1574-84. 2005
    ..Hypothermia is protective against brain injury after asphyxiation in animal models. However, the safety and effectiveness of hypothermia in term infants with encephalopathy is uncertain...
  44. ncbi request reprint To tap or not to tap: high likelihood of meningitis without sepsis among very low birth weight infants
    Barbara J Stoll
    Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA
    Pediatrics 113:1181-6. 2004
    ..We speculated that meningitis may be underdiagnosed among very low birth weight (VLBW) infants because of the failure to perform lumbar punctures (LPs) in infants with suspected sepsis...
  45. ncbi request reprint Association between peak serum bilirubin and neurodevelopmental outcomes in extremely low birth weight infants
    William Oh
    Women and Infants Hospital of Rhode Island Brown University, Providence, Rhode Island 02905, USA
    Pediatrics 112:773-9. 2003
    ..To assess the association between peak total serum bilirubin (PSB) levels during the first 2 weeks of life and neurodevelopmental outcomes of extremely low birth weight (ELBW) infants at 18 to 22 months' postmenstrual age...
  46. ncbi request reprint The role of nutrition in the prevention and management of bronchopulmonary dysplasia
    Manoj A Biniwale
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520, USA
    Semin Perinatol 30:200-8. 2006
    ..Close post discharge follow up of infants with BPD is necessary to monitor growth and to ensure intake of sufficient protein and calories...
  47. ncbi request reprint Predicting outcomes of neonates diagnosed with hypoxemic-ischemic encephalopathy
    Namasivayam Ambalavanan
    Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35249, USA
    Pediatrics 118:2084-93. 2006
    ..The goals were to identify predictor variables and to develop scoring systems and classification trees to predict death/disability or death in infants with hypoxic-ischemic encephalopathy...
  48. ncbi request reprint Trends in neonatal morbidity and mortality for very low birthweight infants
    Avroy A Fanaroff
    Department of Pediatrics, Case Western Reserve University, Cleveland, OH
    Am J Obstet Gynecol 196:147.e1-8. 2007
    ..To document the mortality and morbidity of infants weighing 501-1500 g at birth according to gestational age, birthweight, and sex...
  49. ncbi request reprint Inhaled nitric oxide therapy in neonatal hypoxic respiratory failure: insights beyond primary outcomes
    Gregory M Sokol
    Section of Neonatal Perinatal Medicine, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN 46202 5271, USA
    Semin Perinatol 27:311-9. 2003
    ..It will review the Network's contributions toward advancing the clinical care of the newborn with severe hypoxic respiratory failure...
  50. ncbi request reprint Differential diagnosis and management of anemia in the newborn
    Matthew J Bizzarro
    Department of Pediatrics, Yale University School of Medicine, 333 Cedar Street, P O Box 208064, New Haven, CT 06520 8064, USA
    Pediatr Clin North Am 51:1087-107, xi. 2004
    ..Proper history taking, physical examination, and interpretation of diagnostic tests can narrow this focus and aid in establishing an accurate diagnosis and in directing the appropriate therapeutic interventions...
  51. pmc Outcomes of safety and effectiveness in a multicenter randomized, controlled trial of whole-body hypothermia for neonatal hypoxic-ischemic encephalopathy
    Seetha Shankaran
    Department of Pediatrics, Wayne State University School of Medicine, Detroit, Michigan, USA
    Pediatrics 122:e791-8. 2008
    ..Whole-body hypothermia reduced the frequency of death or moderate/severe disabilities in neonates with hypoxic-ischemic encephalopathy in a randomized, controlled multicenter trial...

Research Grants3

  1. NICHD Cooperative Multicenter Neonatal Research Network
    Richard Ehrenkranz; Fiscal Year: 2006
    ..The NICHD Cooperative Multicenter Neonatal Research Network was established to perform some of those critical studies and to change the culture of neonatology to one of evidence-based medicine. ..
  2. NICHD Cooperative Multicenter Neonatal Research Network
    Richard Ehrenkranz; Fiscal Year: 2007
    ..The NICHD Cooperative Multicenter Neonatal Research Network was established to perform some of those critical studies and to change the culture of neonatology to one of evidence-based medicine. ..