Antonette T Dulay

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi request reprint First-trimester ultrasound: current uses and applications
    Antonette T Dulay
    Division of Maternal Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT, USA
    Semin Ultrasound CT MR 29:121-31. 2008
  2. doi request reprint Soluble TLR2 is present in human amniotic fluid and modulates the intraamniotic inflammatory response to infection
    Antonette T Dulay
    Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA
    J Immunol 182:7244-53. 2009
  3. ncbi request reprint Nucleated red blood cells are a direct response to mediators of inflammation in newborns with early-onset neonatal sepsis
    Antonette T Dulay
    Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520 8063, USA
    Am J Obstet Gynecol 198:426.e1-9. 2008
  4. pmc Activation of the receptor for advanced glycation end products system in women with severe preeclampsia
    Emily A Oliver
    Yale University School of Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, 333 Cedar Street, LLCI 804, New Haven, Connecticut 06520, USA
    J Clin Endocrinol Metab 96:689-98. 2011
  5. pmc Cord blood erythropoietin and interleukin-6 for prediction of intraventricular hemorrhage in the preterm neonate
    Vineet Bhandari
    Division of Perinatal Medicine, Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520, USA
    J Matern Fetal Neonatal Med 24:673-9. 2011
  6. pmc Proteomics mapping of cord blood identifies haptoglobin "switch-on" pattern as biomarker of early-onset neonatal sepsis in preterm newborns
    Catalin S Buhimschi
    Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University, School of Medicine, New Haven, Connecticut, United States of America
    PLoS ONE 6:e26111. 2011
  7. pmc IL-6 trans-signaling system in intra-amniotic inflammation, preterm birth, and preterm premature rupture of the membranes
    Sarah Y Lee
    Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA
    J Immunol 186:3226-36. 2011
  8. pmc Fetal heart rate monitoring patterns in women with amniotic fluid proteomic profiles indicative of inflammation
    Catalin S Buhimschi
    Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut, USA
    Am J Perinatol 25:359-72. 2008
  9. doi request reprint Interpretation of amniotic fluid white blood cell count in "bloody tap" amniocenteses in women with symptoms of preterm labor
    Sonya S Abdel-Razeq
    Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut, USA
    Obstet Gynecol 116:344-54. 2010
  10. pmc Fetal renal artery impedance as assessed by Doppler ultrasound in pregnancies complicated by intraamniotic inflammation and preterm birth
    Humberto Azpurua
    Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA
    Am J Obstet Gynecol 200:203.e1-11. 2009

Collaborators

Detail Information

Publications23

  1. ncbi request reprint First-trimester ultrasound: current uses and applications
    Antonette T Dulay
    Division of Maternal Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT, USA
    Semin Ultrasound CT MR 29:121-31. 2008
    ..We also cover the utility of the first-trimester ultrasound in screening for fetal aneuploidy. Attention is also given to the role of the first-trimester ultrasound in the prediction of adverse perinatal and maternal outcomes...
  2. doi request reprint Soluble TLR2 is present in human amniotic fluid and modulates the intraamniotic inflammatory response to infection
    Antonette T Dulay
    Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA
    J Immunol 182:7244-53. 2009
    ..We conclude that sTLR2 is part of the amniotic fluid innate immune system and participates in regulating the inflammatory response to microbial pathogens...
  3. ncbi request reprint Nucleated red blood cells are a direct response to mediators of inflammation in newborns with early-onset neonatal sepsis
    Antonette T Dulay
    Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520 8063, USA
    Am J Obstet Gynecol 198:426.e1-9. 2008
    ..We sought to determine whether fetal inflammation is associated with an elevation in neonatal NRBC count in the setting of inflammation-associated preterm birth...
  4. pmc Activation of the receptor for advanced glycation end products system in women with severe preeclampsia
    Emily A Oliver
    Yale University School of Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, 333 Cedar Street, LLCI 804, New Haven, Connecticut 06520, USA
    J Clin Endocrinol Metab 96:689-98. 2011
    ..Soluble forms of RAGE [soluble RAGE (sRAGE), endogenous secretory (esRAGE)] bind RAGE ligands, thereby preventing downstream signaling and damage...
  5. pmc Cord blood erythropoietin and interleukin-6 for prediction of intraventricular hemorrhage in the preterm neonate
    Vineet Bhandari
    Division of Perinatal Medicine, Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520, USA
    J Matern Fetal Neonatal Med 24:673-9. 2011
    ..To evaluate cord blood erythropoietin (EPO) and interleukin-6 (IL-6) levels to predict preterm infants at risk of developing intraventricular hemorrhage (IVH)...
  6. pmc Proteomics mapping of cord blood identifies haptoglobin "switch-on" pattern as biomarker of early-onset neonatal sepsis in preterm newborns
    Catalin S Buhimschi
    Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University, School of Medicine, New Haven, Connecticut, United States of America
    PLoS ONE 6:e26111. 2011
    ..A prompt and accurate diagnosis of EONS is critical for improved neonatal outcomes. We sought to explore the cord blood proteome and identify biomarkers and functional protein networks characterizing EONS in preterm newborns...
  7. pmc IL-6 trans-signaling system in intra-amniotic inflammation, preterm birth, and preterm premature rupture of the membranes
    Sarah Y Lee
    Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA
    J Immunol 186:3226-36. 2011
    ..We conclude that IL-6 trans-signaling molecules are physiologic constituents of the AF regulated by gestational age and inflammation. PPROM likely involves functional loss of sgp130...
  8. pmc Fetal heart rate monitoring patterns in women with amniotic fluid proteomic profiles indicative of inflammation
    Catalin S Buhimschi
    Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut, USA
    Am J Perinatol 25:359-72. 2008
    ..An abnormal FHR-MP can thus raise the level of awareness that a fetus with EONS may be born, but it is not a useful clinical indicator of the need for antibiotic treatment of the neonate...
  9. doi request reprint Interpretation of amniotic fluid white blood cell count in "bloody tap" amniocenteses in women with symptoms of preterm labor
    Sonya S Abdel-Razeq
    Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut, USA
    Obstet Gynecol 116:344-54. 2010
    ..To estimate whether blood-contaminated amniotic fluid affects the performance of white blood cell (WBC) count in diagnosing intraamniotic inflammation and infection...
  10. pmc Fetal renal artery impedance as assessed by Doppler ultrasound in pregnancies complicated by intraamniotic inflammation and preterm birth
    Humberto Azpurua
    Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA
    Am J Obstet Gynecol 200:203.e1-11. 2009
    ..The objective of the study was to evaluate the fetal renal artery impedance in the context of inflammation-associated preterm birth...
  11. doi request reprint Ultrasonographic evaluation of myometrial thickness and prediction of a successful external cephalic version
    Catalin S Buhimschi
    Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University, New Haven, CT, USA
    Obstet Gynecol 118:913-20. 2011
    ..To test the hypothesis that myometrial thickness predicts the success of external cephalic version...
  12. pmc Amniotic fluid angiopoietin-1, angiopoietin-2, and soluble receptor tunica interna endothelial cell kinase-2 levels and regulation in normal pregnancy and intraamniotic inflammation-induced preterm birth
    Catalin S Buhimschi
    Yale University School of Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences, 333 Cedar Street, LLCI 804, New Haven, CT 06520, USA
    J Clin Endocrinol Metab 95:3428-36. 2010
    ..Ang-2/Ang-1 ratio may play a role in modulating the fetal inflammatory response to IAI. Placental sTie2 shedding likely involves a Golgi-mediated mechanism...
  13. pmc Using proteomics in perinatal and neonatal sepsis: hopes and challenges for the future
    Catalin S Buhimschi
    Division of Maternal Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT, USA
    Curr Opin Infect Dis 22:235-43. 2009
    ..Proteomics offers the opportunity for detecting fetuses at risk of sepsis and neurological injury...
  14. pmc Modulation of amniotic fluid activin-a and inhibin-a in women with preterm premature rupture of the membranes and infection-induced preterm birth
    Victor A Rosenberg
    Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA
    Am J Reprod Immunol 67:122-31. 2012
    ..We explored activation of amniotic fluid (AF) activin-A and inhibin-A system in women with intra-amniotic infection and preterm premature rupture of the membranes (PPROM)...
  15. ncbi request reprint Is the rate of congenital heart defects detected by fetal echocardiography among pregnancies conceived by in vitro fertilization really increased?: a case-historical control study
    Mert Ozan Bahtiyar
    Section of Maternal Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, 333 Cedar St, PO Box 208063, New Haven, CT 06520 8063, USA
    J Ultrasound Med 29:917-22. 2010
    ..We investigated the prenatal prevalence of congenital heart defects (CHDs) among in vitro fertilization (IVF) pregnancies at a referral program in the United States...
  16. doi request reprint Multidimensional system biology: genetic markers and proteomic biomarkers of adverse pregnancy outcome in preterm birth
    Catalin S Buhimschi
    Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut, USA
    Am J Perinatol 25:175-87. 2008
    ..Genomics and proteomics have emerged to provide a better comprehension of the pathophysiological conditions leading to preterm birth, thereby providing a perspective for improving neonatal outcome...
  17. doi request reprint Heparin elevates circulating soluble fms-like tyrosine kinase-1 immunoreactivity in pregnant women receiving anticoagulation therapy
    Victor A Rosenberg
    Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University, 333 Cedar Street, New Haven, CT 06520, USA
    Circulation 124:2543-53. 2011
    ..Alterations in circulating levels of pro- and antiangiogenic factors have been associated with adverse pregnancy outcomes. Heparin is routinely administered to pregnant women, but without clear knowledge of its impact on these factors...
  18. pmc Characterization of RAGE, HMGB1, and S100beta in inflammation-induced preterm birth and fetal tissue injury
    Catalin S Buhimschi
    Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University, 333 Cedar Street, New Haven, CT 06520, USA
    Am J Pathol 175:958-75. 2009
    ..Our findings indicate that RAGE and HMGB1 may be important mediators of cellular injury in fetuses delivered in the setting of inflammation-induced preterm birth...
  19. pmc Advances in medical diagnosis of intra-amniotic infection
    Irina A Buhimschi
    Yale University, Department of Obstetrics, Gynecology and Reprod Science, New Haven, CT 06520, USA
    Expert Opin Med Diagn 7:5-16. 2013
    ..Prompt and accurate diagnosis of intra-amniotic infection in the asymptomatic stage of the disease is critical for improved maternal and neonatal outcomes...
  20. ncbi request reprint Prenatal course of isolated muscular ventricular septal defects diagnosed only by color Doppler sonography: single-institution experience
    Mert Ozan Bahtiyar
    Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520 8063, USA
    J Ultrasound Med 27:715-20. 2008
    ..The prevalence of these lesions is not yet completely described, and the frequency with which muscular VSDs resolve in utero has also not been extensively reported...
  21. ncbi request reprint Prevalence of congenital heart defects in monochorionic/diamniotic twin gestations: a systematic literature review
    Mert Ozan Bahtiyar
    Section of Maternal Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA
    J Ultrasound Med 26:1491-8. 2007
    ..5% of all neonates. Recent literature points to a possible increase in the CHD prevalence among monochorionic/diamniotic (MC/DA) twin gestations. We hypothesized that MC/DA twin pregnancy is a risk factor for CHD...
  22. doi request reprint Single nucleotide polymorphisms in the human progesterone receptor gene and spontaneous preterm birth
    - Guoyang Luo
    Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut, USA
    Reprod Sci 15:147-55. 2008
    ..5 kg/m(2) (relative risk, 10.8; 95% confidence interval, 1.4-82.6; P = .02). Maternal carriage of minor alleles of +331(G>A), +770(C>T), and +660(G> T) SNPs in the PR gene is not associated with spontaneous preterm birth...
  23. doi request reprint Relationships of maternal serum levels of vascular endothelial growth factor and tensile strength properties of the cervix in a rat model of chronic hypoxia
    Anna K Sfakianaki
    Department of Obstetrics, Gynecology, and Reproductive Science, Yale University School of Medicine, New Haven, CT 06520, USA
    Am J Obstet Gynecol 198:223.e1-7. 2008
    ..In this study, we sought to test the hypothesis that chronic hypoxia increases maternal serum levels of VEGF, which in turn cause measurable changes in the viscoelastic properties of the rat uterine cervix...