Research Topics
| KRISTINA ANNE CROTHERSSummaryAffiliation: Yale University Country: USA Publications
Research Grants
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Detail Information
Publications
Impact of cigarette smoking on mortality in HIV-positive and HIV-negative veteransKristina Crothers
Department of Internal Medicine, VA Connecticut Healthcare System, West Haven, CT 06516, USA
AIDS Educ Prev 21:40-53. 2009..These findings support the need for improvements in smoking cessation and for studies of mechanisms and diseases underlying increased mortality in smokers with HIV...
Pulmonary complications of immune reconstitution inflammatory syndromes in HIV-infected patientsKristina Crothers
Section of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA
Respirology 14:486-94. 2009..Pulmonary complications may be frequently encountered. This article reviews the types and clinical presentation of IRIS, with a focus on the pulmonary manifestations. Management and outcome of IRIS are considered...
Severity and outcome of HIV-associated Pneumocystis pneumonia containing Pneumocystis jirovecii dihydropteroate synthase gene mutationsKristina Crothers
Positive Health Program and Division of Pulmonary and Critical Care Medicine, San Francisco General Hospital, University of California, San Francisco, California, USA
AIDS 19:801-5. 2005..The impact of Pneumocystis jirovecii (formerly P. carinii) dihydropteroate synthase (DHPS) gene mutations on morbidity and mortality of Pneumocystis pneumonia (PCP) in HIV-positive patients is unclear...
Chronic obstructive pulmonary disease in patients who have HIV infectionKristina Crothers
Section of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Yale University School of Medicine, 333 Cedar Street, TAC 441, PO Box 208057, New Haven, CT 06520, USA
Clin Chest Med 28:575-87, vi. 2007..Risk factors for COPD and potential reasons for an increased risk for COPD in HIV-positive patients are discussed. In addition, issues in the management of COPD in HIV-positive patients are reviewed...
Increased COPD among HIV-positive compared to HIV-negative veteransKristina Crothers
Pulmonary and Critical Care Medicine, Department of Internal Medicine, Yale University School of Medicine, New Heaven, CT, USA
Chest 130:1326-33. 2006..The possibility that HIV infection increases susceptibility to and/or accelerates COPD deserves further investigation and has implications regarding the pathogenesis of COPD...
The impact of cigarette smoking on mortality, quality of life, and comorbid illness among HIV-positive veteransKristina Crothers
Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA
J Gen Intern Med 20:1142-5. 2005..These findings suggest that smoking cessation should be emphasized for HIV-infected patients...
Effects of marijuana smoking on pulmonary function and respiratory complications: a systematic reviewJeanette M Tetrault
Clinical Epidemiology Research Center, Department of Veterans Affairs Connecticut Healthcare System, West Haven Veterans Affairs Medical Center, 950 Campbell Avenue, West Haven, CT 06516, USA
Arch Intern Med 167:221-8. 2007....
A theoretical decision model to help inform advance directive discussions for patients with COPDNegin Hajizadeh
Yale Center for Medical Informatics, Yale University School of Medicine, New Haven, USA
BMC Med Inform Decis Mak 10:75. 2010..In order to begin to inform AD discussions between clinicians and COPD patients, we constructed a decision tree to estimate the impact of alternative AD decisions on both quality and quantity of life (quality adjusted life years, QALYs)...
State of the art. Mechanistic heterogeneity in chronic obstructive pulmonary disease: insights from transgenic miceJack A Elias
Section of Pulmonary and Critical Care Medicine, Yale University School of Medicine, 300 Cedar Street, S441 TAC, New Haven, CT 06519, USA
Proc Am Thorac Soc 3:494-8. 2006..They also highlight the complexity of the pathways that can induce alveolar destruction and suggest that there is a continuum, based on VEGF, between asthma and COPD...
Decreased awareness of current smoking among health care providers of HIV-positive compared to HIV-negative veteransKristina Crothers
Pulmonary and Critical Care Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA
J Gen Intern Med 22:749-54. 2007..Cigarette smoking is an important risk factor for morbidity and mortality in HIV-positive patients on combination antiretroviral therapy...
Role of cathepsin S-dependent epithelial cell apoptosis in IFN-gamma-induced alveolar remodeling and pulmonary emphysemaTao Zheng
Department of Internal Medicine, Yale University School of Medicine, Section of Pulmonary and Critical Care Medicine, New Haven, CT 06520, USA
J Immunol 174:8106-15. 2005..They also link inflammation, protease/antiprotease alterations, and protease-dependent apoptosis in the pathogenesis of Th1/Tc1 cytokine-induced tissue remodeling and destructive responses...
Application of an mRNA-based molecular viability assay to oropharyngeal washes for the diagnosis of Pneumocystis pneumonia in HIV-infected patients. A pilot studyLaurence Huang
Division of Pulmonary and Critical Care Medicine and Positive Health Program, San Francisco General Hospital, University of California San Francisco, San Francisco, CA 94110, USA
J Eukaryot Microbiol 50:618-20. 2003
Pneumocystis colonization in HIV-infected patientsLaurence Huang
Division of Pulmonary and Critical Care Medicine and Positive Health Program, San Francisco General Hospital, University of California San Francisco, San Francisco, CA 94110, USA
J Eukaryot Microbiol 50:616-7. 2003
Pneumocystis dihydropteroate synthase mutations in patients with Pneumocystis pneumonia who are newly diagnosed with HIV infectionKristina Crothers
Division of Pulmonary and Critical Care Medicine and Positive Health Program, San Francisco General Hospital, University of California San Francisco, San Francisco, CA 94110, USA
J Eukaryot Microbiol 50:609-10. 2003
HIV-associated opportunistic pneumoniasLaurence Huang
Division of Pulmonary, Department of Medicine, San Francisco General Hospital, University of California San Francisco, San Francisco, CA 94110, USA
Respirology 14:474-85. 2009....
Research Grants
- Longitudinal Studies of HIV-Associated Lung Infections and ComplicationsKristina Crothers; Fiscal Year: 2007..Furthermore, insights into reasons for susceptibility to OLD and accelerated progression of OLD can improve care for both HIV+ and HIV-patients. ..
