Philip R Corlett

Summary

Affiliation: Yale University
Country: USA

Publications

  1. pmc Ketamine effects on memory reconsolidation favor a learning model of delusions
    Philip R Corlett
    Department of Psychiatry, Ribicoff Research Facility, Yale University, New Haven, Connecticut, United States of America
    PLoS ONE 8:e65088. 2013
  2. pmc The neurobiology of schizotypy: fronto-striatal prediction error signal correlates with delusion-like beliefs in healthy people
    P R Corlett
    Connecticut Mental Health Center, Yale University, Department of Psychiatry, Ribicoff Research Facility 34 Park Street, New Haven, CT 06519, USA
    Neuropsychologia 50:3612-20. 2012
  3. pmc Why do delusions persist?
    Philip R Corlett
    Department of Psychiatry, School of Medicine, Yale University New Haven, CT 06519, USA
    Front Hum Neurosci 3:12. 2009
  4. pmc Glutamatergic model psychoses: prediction error, learning, and inference
    Philip R Corlett
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Neuropsychopharmacology 36:294-315. 2011
  5. pmc Toward a neurobiology of delusions
    P R Corlett
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Centre, Abraham Ribicoff Research Facility, 34 Park Street, New Haven, CT 06519, USA
    Prog Neurobiol 92:345-69. 2010
  6. pmc Linking microcircuit dysfunction to cognitive impairment: effects of disinhibition associated with schizophrenia in a cortical working memory model
    John D Murray
    Department of Physics, Yale University, New Haven, CT 06520, USA
    Cereb Cortex 24:859-72. 2014
  7. pmc The role of default network deactivation in cognition and disease
    Alan Anticevic
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, USA
    Trends Cogn Sci 16:584-92. 2012
  8. doi request reprint Two cases of delayed-onset suicidal ideation, dysphoria and anxiety after ketamine infusion in patients with obsessive-compulsive disorder and a history of major depressive disorder
    Mark J Niciu
    Yale University, Department of Psychiatry Connecticut Mental Health Center CMHC, Clinical Neuroscience Research Unit CNRU, New Haven, Connecticut, USA
    J Psychopharmacol 27:651-4. 2013
  9. pmc NMDA receptor function in large-scale anticorrelated neural systems with implications for cognition and schizophrenia
    Alan Anticevic
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, USA
    Proc Natl Acad Sci U S A 109:16720-5. 2012
  10. pmc Aberrant learning and memory in addiction
    Mary M Torregrossa
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06508, USA
    Neurobiol Learn Mem 96:609-23. 2011

Detail Information

Publications12

  1. pmc Ketamine effects on memory reconsolidation favor a learning model of delusions
    Philip R Corlett
    Department of Psychiatry, Ribicoff Research Facility, Yale University, New Haven, Connecticut, United States of America
    PLoS ONE 8:e65088. 2013
    ..These results suggest a link between altered prediction error, memory strength and psychosis. They point to a core disruption that may explain not only the emergence of delusional beliefs but also their persistence...
  2. pmc The neurobiology of schizotypy: fronto-striatal prediction error signal correlates with delusion-like beliefs in healthy people
    P R Corlett
    Connecticut Mental Health Center, Yale University, Department of Psychiatry, Ribicoff Research Facility 34 Park Street, New Haven, CT 06519, USA
    Neuropsychologia 50:3612-20. 2012
    ....
  3. pmc Why do delusions persist?
    Philip R Corlett
    Department of Psychiatry, School of Medicine, Yale University New Haven, CT 06519, USA
    Front Hum Neurosci 3:12. 2009
    ..We argue that, under the influence of excessive prediction error, delusional beliefs are repeatedly reconsolidated, strengthening them so that they persist, apparently impervious to contradiction...
  4. pmc Glutamatergic model psychoses: prediction error, learning, and inference
    Philip R Corlett
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Neuropsychopharmacology 36:294-315. 2011
    ....
  5. pmc Toward a neurobiology of delusions
    P R Corlett
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Centre, Abraham Ribicoff Research Facility, 34 Park Street, New Haven, CT 06519, USA
    Prog Neurobiol 92:345-69. 2010
    ..The present model attempts to provide a framework through which we can build a mechanistic and translational understanding of these puzzling symptoms...
  6. pmc Linking microcircuit dysfunction to cognitive impairment: effects of disinhibition associated with schizophrenia in a cortical working memory model
    John D Murray
    Department of Physics, Yale University, New Haven, CT 06520, USA
    Cereb Cortex 24:859-72. 2014
    ..Our findings identify specific ways by which cortical disinhibition affects WM, suggesting new experimental designs for probing the brain mechanisms of WM deficits in schizophrenia. ..
  7. pmc The role of default network deactivation in cognition and disease
    Alan Anticevic
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, USA
    Trends Cogn Sci 16:584-92. 2012
    ..g., mind-wandering), and illustrates the functional significance of DMN suppression deficits in severe mental illness...
  8. doi request reprint Two cases of delayed-onset suicidal ideation, dysphoria and anxiety after ketamine infusion in patients with obsessive-compulsive disorder and a history of major depressive disorder
    Mark J Niciu
    Yale University, Department of Psychiatry Connecticut Mental Health Center CMHC, Clinical Neuroscience Research Unit CNRU, New Haven, Connecticut, USA
    J Psychopharmacol 27:651-4. 2013
    ..We conclude that there remains insufficient data on therapeutic ketamine in the presence of comorbid psychiatric disorders to promote its off-label use in a non-research milieu. ..
  9. pmc NMDA receptor function in large-scale anticorrelated neural systems with implications for cognition and schizophrenia
    Alan Anticevic
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, USA
    Proc Natl Acad Sci U S A 109:16720-5. 2012
    ..Together, the present findings establish links between glutamate's role in the organization of large-scale anticorrelated neural systems, cognition, and symptoms associated with schizophrenia in humans...
  10. pmc Aberrant learning and memory in addiction
    Mary M Torregrossa
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06508, USA
    Neurobiol Learn Mem 96:609-23. 2011
    ....
  11. pmc Cognition-emotion dysinteraction in schizophrenia
    Alan Anticevic
    Clinical Neuroscience Research Unit, Ribicoff Research Facilities, Connecticut Mental Health Center, Department of Psychiatry, Yale University School of Medicine New Haven, CT, USA
    Front Psychol 3:392. 2012
    ..We conclude with a brief treatment of the neurobiology of schizophrenia and the need to close our explanatory gap between cellular-level hypotheses and complex behavioral symptoms observed in this illness...