Research Topics
| R A ChambersSummaryAffiliation: Yale University Country: USA Publications
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Detail Information
Publications
Droperidol: efficacy and side effects in psychiatric emergenciesR A Chambers
Department of Psychiatry, Yale University School of Medicine, New Haven, Conn, USA
J Clin Psychiatry 60:664-7. 1999..This article reviews the evidence that droperidol may serve as the optimal medication for this task...
Motivational responses to natural and drug rewards in rats with neonatal ventral hippocampal lesions: an animal model of dual diagnosis schizophreniaR Andrew Chambers
Division of Molecular Psychiatry, West Haven Veterans Administration Hospital, USA
Neuropsychopharmacology 27:889-905. 2002....
Neurodevelopment, impulsivity, and adolescent gamblingR Andrew Chambers
Yale University School of Medicine, USA
J Gambl Stud 19:53-84. 2003..An exploration of the developmental changes in neural circuitry involved in impulse control has significant implications for understanding adolescent behaviors and treating problem and pathological gambling among youths...
Developmental neurocircuitry of motivation in adolescence: a critical period of addiction vulnerabilityR Andrew Chambers
Connecticut Mental Health Center, the Problem Grambling Clinic, Yale University School of Medicine, New Haven, CT 06508, USA
Am J Psychiatry 160:1041-52. 2003..The authors describe basic and clinical data supporting adolescent neurodevelopment as a biologically critical period of greater vulnerability for experimentation with substances and acquisition of substance use disorders...
A neurobiological basis for substance abuse comorbidity in schizophreniaR A Chambers
Ribicoff Research Facilities, West Haven Veterans Administration Hospital, Connecticut, USA
Biol Psychiatry 50:71-83. 2001..Thus, schizophrenic patients may have a predilection for addictive behavior as a primary disease symptom in parallel to, and in many, cases independent from, their other symptoms...
Accentuated behavioral sensitization to nicotine in the neonatal ventral hippocampal lesion model of schizophreniaSarah A Berg
Laboratory for Translational Neuroscience of Dual Diagnosis and Development, Institute of Psychiatric Research, Department of Psychiatry, Indiana University School of Medicine, 791 Union Drive, Indianapolis, IN 46202, USA
Neuropharmacology 54:1201-7. 2008....
Cortical-striatal integration of cocaine history and prefrontal dysfunction in animal modeling of dual diagnosisR Andrew Chambers
Laboratory for Translational Neuroscience of Dual Diagnosis and Development, Department of Psychiatry, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
Biol Psychiatry 67:788-92. 2010..Interactions between addictive drug effects and mental illness involving circuits that generate motivated behavior may underpin this vulnerability...
Ethanol sensitization in a neurodevelopmental lesion model of schizophrenia in ratsSusan K Conroy
Laboratory for Translational Neuroscience of Dual Diagnosis Disorders, Institute of Psychiatric Research, Department of Psychiatry, Indiana University School of Medicine, 791 Union Drive Indianapolis, IN 46202, USA
Pharmacol Biochem Behav 86:386-94. 2007....
The Dual Diagnosis Physician-infrastructure Assessment Tool: examining physician attributes and dual diagnosis capacityR Andrew Chambers
Institute of Psychiatric Research, Department of Psychiatry, Indiana University School of Medicine, 791 Union Dr, Indianapolis, IN 46202, USA
Psychiatr Serv 61:184-8. 2010..The authors designed and implemented the Dual Diagnosis Physician-infrastructure Assessment Tool (DDPAT) to quantify statewide dimensions of this workforce problem...
Simulated apoptosis/neurogenesis regulates learning and memory capabilities of adaptive neural networksR Andrew Chambers
Division of Substance Abuse, Connecticut Mental Health Center, Yale University School of Medicine, USA
Neuropsychopharmacology 29:747-58. 2004..The implications of these elementary simulations for future biological and neural modeling research on apoptosis and neurogenesis are discussed...
A scale-free systems theory of motivation and addictionR Andrew Chambers
Lab for Translational Neuroscience of Dual Diagnosis and Development, Institute of Psychiatric Research, Indiana Division of Mental Health and Addiction, Indiana University School of Medicine, 791 Union Drive, Indianapolis, IN 46202, USA
Neurosci Biobehav Rev 31:1017-45. 2007..This model may inform integrative research in defining more effective prevention and treatment strategies for addiction...
Animal modeling dual diagnosis schizophrenia: sensitization to cocaine in rats with neonatal ventral hippocampal lesionsR Andrew Chambers
Laboratory for Translational Neuroscience of Dual Diagnosis Disorders RAC, Institute of Psychiatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA
Biol Psychiatry 56:308-16. 2004..Increased substance disorder comorbidity in schizophrenia may reflect greater vulnerability to addictive processes because of inherent neurocircuit dysfunction in the schizophrenic brain...
Natural reward-related learning in rats with neonatal ventral hippocampal lesions and prior cocaine exposureR Andrew Chambers
Laboratory for Translational Neuroscience of Dual Diagnosis Disorders, Institute of Psychiatric Research, Indiana University School of Medicine, 791 Union Drive, Indianapolis, IN 46202, USA
Psychopharmacology (Berl) 179:470-8. 2005..These effects may represent a persistent impact of drugs on neurocircuits that interface cognitive and motivational processes, which may be further altered in neuropsychiatric conditions that entail increased addiction vulnerability...
Huntington disease as a dual diagnosis disorder: data from the National Research Roster for Huntington disease patients and familiesJason C Ehret
Department of Psychiatry, Indiana University School of Medicine, IPR, 791 Union Drive, Indinapolis, IN 46202, United States
Drug Alcohol Depend 86:283-6. 2007..These findings suggest HD entails dual diagnosis phenomena similar to that identified in patients with primary psychiatric disorders...
Network modeling of adult neurogenesis: shifting rates of neuronal turnover optimally gears network learning according to novelty gradientR Andrew Chambers
Indiana University School of Medicine, USA
J Cogn Neurosci 19:1-12. 2007....
