R A Chambers

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi request reprint Droperidol: efficacy and side effects in psychiatric emergencies
    R A Chambers
    Department of Psychiatry, Yale University School of Medicine, New Haven, Conn, USA
    J Clin Psychiatry 60:664-7. 1999
  2. pmc Motivational responses to natural and drug rewards in rats with neonatal ventral hippocampal lesions: an animal model of dual diagnosis schizophrenia
    R Andrew Chambers
    Division of Molecular Psychiatry, West Haven Veterans Administration Hospital, USA
    Neuropsychopharmacology 27:889-905. 2002
  3. ncbi request reprint Neurodevelopment, impulsivity, and adolescent gambling
    R Andrew Chambers
    Yale University School of Medicine, USA
    J Gambl Stud 19:53-84. 2003
  4. pmc Developmental neurocircuitry of motivation in adolescence: a critical period of addiction vulnerability
    R Andrew Chambers
    Connecticut Mental Health Center, the Problem Grambling Clinic, Yale University School of Medicine, New Haven, CT 06508, USA
    Am J Psychiatry 160:1041-52. 2003
  5. pmc A neurobiological basis for substance abuse comorbidity in schizophrenia
    R A Chambers
    Ribicoff Research Facilities, West Haven Veterans Administration Hospital, Connecticut, USA
    Biol Psychiatry 50:71-83. 2001
  6. doi request reprint Cortical-striatal gene expression in neonatal hippocampal lesion (NVHL)-amplified cocaine sensitization
    R A Chambers
    Lab for Translational Neuroscience of Dual Diagnosis and Development, Department of Psychiatry, Institute for Psychiatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Genes Brain Behav 12:564-75. 2013
  7. pmc Accentuated behavioral sensitization to nicotine in the neonatal ventral hippocampal lesion model of schizophrenia
    Sarah A Berg
    Laboratory for Translational Neuroscience of Dual Diagnosis and Development, Institute of Psychiatric Research, Department of Psychiatry, Indiana University School of Medicine, 791 Union Drive, Indianapolis, IN 46202, USA
    Neuropharmacology 54:1201-7. 2008
  8. pmc Ethanol sensitization in a neurodevelopmental lesion model of schizophrenia in rats
    Susan K Conroy
    Laboratory for Translational Neuroscience of Dual Diagnosis Disorders, Institute of Psychiatric Research, Department of Psychiatry, Indiana University School of Medicine, 791 Union Drive Indianapolis, IN 46202, USA
    Pharmacol Biochem Behav 86:386-94. 2007
  9. pmc Cortical-striatal integration of cocaine history and prefrontal dysfunction in animal modeling of dual diagnosis
    R Andrew Chambers
    Laboratory for Translational Neuroscience of Dual Diagnosis and Development, Department of Psychiatry, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Biol Psychiatry 67:788-92. 2010
  10. pmc The Dual Diagnosis Physician-infrastructure Assessment Tool: examining physician attributes and dual diagnosis capacity
    R Andrew Chambers
    Institute of Psychiatric Research, Department of Psychiatry, Indiana University School of Medicine, 791 Union Dr, Indianapolis, IN 46202, USA
    Psychiatr Serv 61:184-8. 2010

Collaborators

Detail Information

Publications16

  1. ncbi request reprint Droperidol: efficacy and side effects in psychiatric emergencies
    R A Chambers
    Department of Psychiatry, Yale University School of Medicine, New Haven, Conn, USA
    J Clin Psychiatry 60:664-7. 1999
    ..This article reviews the evidence that droperidol may serve as the optimal medication for this task...
  2. pmc Motivational responses to natural and drug rewards in rats with neonatal ventral hippocampal lesions: an animal model of dual diagnosis schizophrenia
    R Andrew Chambers
    Division of Molecular Psychiatry, West Haven Veterans Administration Hospital, USA
    Neuropsychopharmacology 27:889-905. 2002
    ....
  3. ncbi request reprint Neurodevelopment, impulsivity, and adolescent gambling
    R Andrew Chambers
    Yale University School of Medicine, USA
    J Gambl Stud 19:53-84. 2003
    ..An exploration of the developmental changes in neural circuitry involved in impulse control has significant implications for understanding adolescent behaviors and treating problem and pathological gambling among youths...
  4. pmc Developmental neurocircuitry of motivation in adolescence: a critical period of addiction vulnerability
    R Andrew Chambers
    Connecticut Mental Health Center, the Problem Grambling Clinic, Yale University School of Medicine, New Haven, CT 06508, USA
    Am J Psychiatry 160:1041-52. 2003
    ..The authors describe basic and clinical data supporting adolescent neurodevelopment as a biologically critical period of greater vulnerability for experimentation with substances and acquisition of substance use disorders...
  5. pmc A neurobiological basis for substance abuse comorbidity in schizophrenia
    R A Chambers
    Ribicoff Research Facilities, West Haven Veterans Administration Hospital, Connecticut, USA
    Biol Psychiatry 50:71-83. 2001
    ..Thus, schizophrenic patients may have a predilection for addictive behavior as a primary disease symptom in parallel to, and in many, cases independent from, their other symptoms...
  6. doi request reprint Cortical-striatal gene expression in neonatal hippocampal lesion (NVHL)-amplified cocaine sensitization
    R A Chambers
    Lab for Translational Neuroscience of Dual Diagnosis and Development, Department of Psychiatry, Institute for Psychiatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Genes Brain Behav 12:564-75. 2013
    ..Polygenetic interactions impacting neuronal signaling and morphology within these networks likely contribute to addiction vulnerability in mental illness. ..
  7. pmc Accentuated behavioral sensitization to nicotine in the neonatal ventral hippocampal lesion model of schizophrenia
    Sarah A Berg
    Laboratory for Translational Neuroscience of Dual Diagnosis and Development, Institute of Psychiatric Research, Department of Psychiatry, Indiana University School of Medicine, 791 Union Drive, Indianapolis, IN 46202, USA
    Neuropharmacology 54:1201-7. 2008
    ....
  8. pmc Ethanol sensitization in a neurodevelopmental lesion model of schizophrenia in rats
    Susan K Conroy
    Laboratory for Translational Neuroscience of Dual Diagnosis Disorders, Institute of Psychiatric Research, Department of Psychiatry, Indiana University School of Medicine, 791 Union Drive Indianapolis, IN 46202, USA
    Pharmacol Biochem Behav 86:386-94. 2007
    ....
  9. pmc Cortical-striatal integration of cocaine history and prefrontal dysfunction in animal modeling of dual diagnosis
    R Andrew Chambers
    Laboratory for Translational Neuroscience of Dual Diagnosis and Development, Department of Psychiatry, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Biol Psychiatry 67:788-92. 2010
    ..Interactions between addictive drug effects and mental illness involving circuits that generate motivated behavior may underpin this vulnerability...
  10. pmc The Dual Diagnosis Physician-infrastructure Assessment Tool: examining physician attributes and dual diagnosis capacity
    R Andrew Chambers
    Institute of Psychiatric Research, Department of Psychiatry, Indiana University School of Medicine, 791 Union Dr, Indianapolis, IN 46202, USA
    Psychiatr Serv 61:184-8. 2010
    ..The authors designed and implemented the Dual Diagnosis Physician-infrastructure Assessment Tool (DDPAT) to quantify statewide dimensions of this workforce problem...
  11. ncbi request reprint Simulated apoptosis/neurogenesis regulates learning and memory capabilities of adaptive neural networks
    R Andrew Chambers
    Division of Substance Abuse, Connecticut Mental Health Center, Yale University School of Medicine, USA
    Neuropsychopharmacology 29:747-58. 2004
    ..The implications of these elementary simulations for future biological and neural modeling research on apoptosis and neurogenesis are discussed...
  12. ncbi request reprint Animal modeling dual diagnosis schizophrenia: sensitization to cocaine in rats with neonatal ventral hippocampal lesions
    R Andrew Chambers
    Laboratory for Translational Neuroscience of Dual Diagnosis Disorders RAC, Institute of Psychiatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Biol Psychiatry 56:308-16. 2004
    ..Increased substance disorder comorbidity in schizophrenia may reflect greater vulnerability to addictive processes because of inherent neurocircuit dysfunction in the schizophrenic brain...
  13. pmc A scale-free systems theory of motivation and addiction
    R Andrew Chambers
    Lab for Translational Neuroscience of Dual Diagnosis and Development, Institute of Psychiatric Research, Indiana Division of Mental Health and Addiction, Indiana University School of Medicine, 791 Union Drive, Indianapolis, IN 46202, USA
    Neurosci Biobehav Rev 31:1017-45. 2007
    ..This model may inform integrative research in defining more effective prevention and treatment strategies for addiction...
  14. pmc Natural reward-related learning in rats with neonatal ventral hippocampal lesions and prior cocaine exposure
    R Andrew Chambers
    Laboratory for Translational Neuroscience of Dual Diagnosis Disorders, Institute of Psychiatric Research, Indiana University School of Medicine, 791 Union Drive, Indianapolis, IN 46202, USA
    Psychopharmacology (Berl) 179:470-8. 2005
    ..These effects may represent a persistent impact of drugs on neurocircuits that interface cognitive and motivational processes, which may be further altered in neuropsychiatric conditions that entail increased addiction vulnerability...
  15. pmc Network modeling of adult neurogenesis: shifting rates of neuronal turnover optimally gears network learning according to novelty gradient
    R Andrew Chambers
    Indiana University School of Medicine, USA
    J Cogn Neurosci 19:1-12. 2007
    ....
  16. pmc Huntington disease as a dual diagnosis disorder: data from the National Research Roster for Huntington disease patients and families
    Jason C Ehret
    Department of Psychiatry, Indiana University School of Medicine, IPR, 791 Union Drive, Indinapolis, IN 46202, United States
    Drug Alcohol Depend 86:283-6. 2007
    ..These findings suggest HD entails dual diagnosis phenomena similar to that identified in patients with primary psychiatric disorders...