K M Carroll

Summary

Affiliation: Yale University
Country: USA

Publications

  1. pmc Toward empirical identification of a clinically meaningful indicator of treatment outcome: features of candidate indicators and evaluation of sensitivity to treatment effects and relationship to one year follow up cocaine use outcomes
    Kathleen M Carroll
    Department of Psychiatry, Yale University School of Medicine, 950 Campbell Avenue, 151D, West Haven, CT 06516, United States Electronic address
    Drug Alcohol Depend 137:3-19. 2014
  2. pmc Efficacy of disulfiram and Twelve Step Facilitation in cocaine-dependent individuals maintained on methadone: a randomized placebo-controlled trial
    Kathleen M Carroll
    Department of Psychiatry, Yale University School of Medicine, 950 Campbell Avenue, 151D, West Haven, CT 06516, USA
    Drug Alcohol Depend 126:224-31. 2012
  3. pmc Combining cognitive behavioral therapy and contingency management to enhance their effects in treating cannabis dependence: less can be more, more or less
    Kathleen M Carroll
    Division of Substance Abuse, Yale University School of Medicine, New Haven, CT 06516, USA
    Addiction 107:1650-9. 2012
  4. pmc Motivational interviewing to enhance treatment initiation in substance abusers: an effectiveness study
    K M Carroll
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Am J Addict 10:335-9. 2001
  5. pmc Bridging the gap: a hybrid model to link efficacy and effectiveness research in substance abuse treatment
    Kathleen M Carroll
    Department of Psychiatry at Yale University School of Medicine, West Haven, Connecticut, USA
    Psychiatr Serv 54:333-9. 2003
  6. pmc A multisite randomized effectiveness trial of motivational enhancement therapy for Spanish-speaking substance users
    Kathleen M Carroll
    Department of Psychiatry, Yale University School of Medicine, West Haven, CT 06519, USA
    J Consult Clin Psychol 77:993-9. 2009
  7. pmc Enduring effects of a computer-assisted training program for cognitive behavioral therapy: a 6-month follow-up of CBT4CBT
    Kathleen M Carroll
    Yale University School of Medicine, Division of Substance Abuse, 950 Campbell Avenue, 151D West Haven, CT 06516, USA
    Drug Alcohol Depend 100:178-81. 2009
  8. pmc Computer-assisted delivery of cognitive-behavioral therapy for addiction: a randomized trial of CBT4CBT
    Kathleen M Carroll
    Division of Substance Abuse, Yale University School of Medicine, 950 Campbell Ave, 151D, West Haven, CT 06516, USA
    Am J Psychiatry 165:881-8. 2008
  9. pmc Efficacy of disulfiram and cognitive behavior therapy in cocaine-dependent outpatients: a randomized placebo-controlled trial
    Kathleen M Carroll
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06516, USA
    Arch Gen Psychiatry 61:264-72. 2004
  10. pmc A vision of the next generation of behavioral therapies research in the addictions
    Kathleen M Carroll
    Division of Substance Abuse, Yale University School of Medicine, West Haven, CT 06516, USA
    Addiction 102:850-62; discussion 863-9. 2007

Research Grants

  1. Computer-Based Training in Cognitve Behavioral Therapy
    Kathleen Carroll; Fiscal Year: 2002
  2. Maximizing CBT's Efficacy with Medication & CM
    Kathleen Carroll; Fiscal Year: 2009
  3. Maximizing CBT's Efficacy with Medication & CM
    Kathleen Carroll; Fiscal Year: 2006
  4. Maximizing CBT's Efficacy with Medication & CM
    Kathleen Carroll; Fiscal Year: 2007
  5. CLINICAL TRIALS NETWORK: NEW ENGLAND NODE
    Kathleen Carroll; Fiscal Year: 2006
  6. Maximizing Effectiveness of Cognitive Behavior Therapy and Contingency Management
    Kathleen Carroll; Fiscal Year: 2007
  7. Computer-Based Training in Cognitve Behavioral Therapy
    Kathleen Carroll; Fiscal Year: 2007
  8. CLINICAL TRIALS NETWORK: NEW ENGLAND NODE
    Kathleen Carroll; Fiscal Year: 2007
  9. PSYCHOTHERAPY OF SUBSTANCE USE DISORDERS
    Kathleen Carroll; Fiscal Year: 2007
  10. CLINICAL TRIALS NETWORK: NEW ENGLAND NODE
    Kathleen Carroll; Fiscal Year: 2005

Detail Information

Publications91

  1. pmc Toward empirical identification of a clinically meaningful indicator of treatment outcome: features of candidate indicators and evaluation of sensitivity to treatment effects and relationship to one year follow up cocaine use outcomes
    Kathleen M Carroll
    Department of Psychiatry, Yale University School of Medicine, 950 Campbell Avenue, 151D, West Haven, CT 06516, United States Electronic address
    Drug Alcohol Depend 137:3-19. 2014
    ..Absence of an evidence-based, clinically meaningful index of treatment outcome hinders cross-study evaluations necessary for progress in addiction treatment science...
  2. pmc Efficacy of disulfiram and Twelve Step Facilitation in cocaine-dependent individuals maintained on methadone: a randomized placebo-controlled trial
    Kathleen M Carroll
    Department of Psychiatry, Yale University School of Medicine, 950 Campbell Avenue, 151D, West Haven, CT 06516, USA
    Drug Alcohol Depend 126:224-31. 2012
    ....
  3. pmc Combining cognitive behavioral therapy and contingency management to enhance their effects in treating cannabis dependence: less can be more, more or less
    Kathleen M Carroll
    Division of Substance Abuse, Yale University School of Medicine, New Haven, CT 06516, USA
    Addiction 107:1650-9. 2012
    ....
  4. pmc Motivational interviewing to enhance treatment initiation in substance abusers: an effectiveness study
    K M Carroll
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Am J Addict 10:335-9. 2001
    ..Moreover, this study adds to an overwhelmingly positive literature supporting Motivational Interviewing with alcohol-using populations and extends prior findings to non-research community settings...
  5. pmc Bridging the gap: a hybrid model to link efficacy and effectiveness research in substance abuse treatment
    Kathleen M Carroll
    Department of Psychiatry at Yale University School of Medicine, West Haven, Connecticut, USA
    Psychiatr Serv 54:333-9. 2003
    ..Such issues include diversity in settings, clinicians, and patients; cost-effectiveness of treatment; training issues; and patient and clinician satisfaction...
  6. pmc A multisite randomized effectiveness trial of motivational enhancement therapy for Spanish-speaking substance users
    Kathleen M Carroll
    Department of Psychiatry, Yale University School of Medicine, West Haven, CT 06519, USA
    J Consult Clin Psychol 77:993-9. 2009
    ....
  7. pmc Enduring effects of a computer-assisted training program for cognitive behavioral therapy: a 6-month follow-up of CBT4CBT
    Kathleen M Carroll
    Yale University School of Medicine, Division of Substance Abuse, 950 Campbell Avenue, 151D West Haven, CT 06516, USA
    Drug Alcohol Depend 100:178-81. 2009
    ..To evaluate the durability of effects of a computer-assisted version of cognitive behavioral therapy (CBT) as treatment for substance dependence through a 6-month follow-up...
  8. pmc Computer-assisted delivery of cognitive-behavioral therapy for addiction: a randomized trial of CBT4CBT
    Kathleen M Carroll
    Division of Substance Abuse, Yale University School of Medicine, 950 Campbell Ave, 151D, West Haven, CT 06516, USA
    Am J Psychiatry 165:881-8. 2008
    ..This study evaluated the efficacy of a computer-based version of cognitive-behavioral therapy (CBT) for substance dependence...
  9. pmc Efficacy of disulfiram and cognitive behavior therapy in cocaine-dependent outpatients: a randomized placebo-controlled trial
    Kathleen M Carroll
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06516, USA
    Arch Gen Psychiatry 61:264-72. 2004
    ..Disulfiram has emerged as a promising treatment for cocaine dependence, but it has not yet been evaluated in general populations of cocaine users...
  10. pmc A vision of the next generation of behavioral therapies research in the addictions
    Kathleen M Carroll
    Division of Substance Abuse, Yale University School of Medicine, West Haven, CT 06516, USA
    Addiction 102:850-62; discussion 863-9. 2007
    ....
  11. pmc The use of contingency management and motivational/skills-building therapy to treat young adults with marijuana dependence
    Kathleen M Carroll
    Division of Substance Abuse, Yale University School of Medicine, West Haven, CT 06516, USA
    J Consult Clin Psychol 74:955-66. 2006
    ..Participants assigned to MET/CBT continued to reduce the frequency of their marijuana use through a 6-month follow-up...
  12. pmc Choosing a behavioral therapy platform for pharmacotherapy of substance users
    Kathleen M Carroll
    Department of Psychiatry, Yale University School of Medicine, VA CT Healthcare Center, 950 Campbell Avenue, West Haven, CT 06516, USA
    Drug Alcohol Depend 75:123-34. 2004
    ..Available manualized behavioral treatments are reviewed, noting their strengths and limitations as behavioral therapy platforms for pharmacotherapy trials and as potential concomitant therapies in clinical practice...
  13. ncbi request reprint Recent advances in the psychotherapy of addictive disorders
    Kathleen M Carroll
    Yale University School of Medicine, Division of Substance Abuse, 950 Campbell Avenue 151D, West Haven, CT 06516, USA
    Curr Psychiatry Rep 7:329-36. 2005
    ....
  14. pmc Practice makes progress? Homework assignments and outcome in treatment of cocaine dependence
    Kathleen M Carroll
    Division of Substance Abuse, Department of Psychiatry, Yale University School of Medicine, New Haven, CT 006516, USA
    J Consult Clin Psychol 73:749-55. 2005
    ..These data suggest that the extent to which participants are willing to complete extrasession assignments may be an important mediator of response to CBT...
  15. pmc Behavioral therapies for co-occurring substance use and mood disorders
    Kathleen M Carroll
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06516, USA
    Biol Psychiatry 56:778-84. 2004
    ....
  16. pmc Motivational interviewing to improve treatment engagement and outcome in individuals seeking treatment for substance abuse: a multisite effectiveness study
    Kathleen M Carroll
    Division of Substance Abuse, Department of Psychiatry, Yale University School of Medicine, 950 Campbell Avenue, West Haven, CT 06516, USA
    Drug Alcohol Depend 81:301-12. 2006
    ....
  17. pmc Computer-assisted therapy in psychiatry: be brave-it's a new world
    Kathleen M Carroll
    Division of Substance Abuse, Yale University School of Medicine, West Haven, CT 06516, USA
    Curr Psychiatry Rep 12:426-32. 2010
    ....
  18. pmc Cognitive function and treatment response in a randomized clinical trial of computer-based training in cognitive-behavioral therapy
    Kathleen M Carroll
    Division of Substance Abuse, Yale University School of Medicine, 950 Campbell Avenue, West Haven, CT 06516, USA
    Subst Use Misuse 46:23-34. 2011
    ..Those with higher levels of risk taking completed fewer sessions and homework assignments and had poorer substance use outcomes...
  19. pmc On beyond urine: clinically useful assessment instruments in the treatment of drug dependence
    K M Carroll
    Division of Substance Abuse, VA CT Healthcare Center 151D, West Haven, CT 06516, USA
    Behav Res Ther 40:1329-44. 2002
    ..Progress in the field of drug abuse treatment has been significantly hampered by the failure to adopt, across research and clinical settings, a common set of assessments...
  20. ncbi request reprint Internal validity of Project MATCH treatments: discriminability and integrity
    K M Carroll
    Yale University School of Medicine, New Haven, Connecticut, USA
    J Consult Clin Psychol 66:290-303. 1998
    ..Nonspecific aspects of treatment such as therapist skillfulness and level of the therapeutic alliance were comparable across treatment conditions...
  21. ncbi request reprint A general system for evaluating therapist adherence and competence in psychotherapy research in the addictions
    K M Carroll
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Drug Alcohol Depend 57:225-38. 2000
    ..Strategies for using the YACS in both psychotherapy and pharmacotherapy research in the addictions are described...
  22. ncbi request reprint One-year follow-up of disulfiram and psychotherapy for cocaine-alcohol users: sustained effects of treatment
    K M Carroll
    Department of Psychiatry, Yale University School of Medicine, USA
    Addiction 95:1335-49. 2000
    ..To evaluate outcomes 1 year after cessation of treatment for cocaine- and alcohol-dependent individuals...
  23. ncbi request reprint Implications of recent research for program quality in cocaine dependence treatment
    K M Carroll
    Division of Substance Abuse, Yale University School of Medicine, New Haven, Connecticut 06519, USA
    Subst Use Misuse 35:2011-30. 2000
    ..Finally, greater adoption by treatment providers of strategies commonly used in treatment efficacy research might also contribute to improved treatment quality...
  24. pmc Targeting behavioral therapies to enhance naltrexone treatment of opioid dependence: efficacy of contingency management and significant other involvement
    K M Carroll
    Department of Psychiatry, Yale University School of Medicine, VA CT Healthcare System, 950 Campbell Ave 151D, West Haven, CT 06516, USA
    Arch Gen Psychiatry 58:755-61. 2001
    ..Contingency management (CM) and significant other involvement (SO) were evaluated as strategies to enhance treatment retention, medication compliance, and outcome for naltrexone treatment of opioid dependence...
  25. pmc A perfect platform: combining contingency management with medications for drug abuse
    Kathleen M Carroll
    Division of Substance Abuse, Department of Psychiatry, Yale University School of Medicine, West Haven, Connecticut 06516, USA
    Am J Drug Alcohol Abuse 33:343-65. 2007
    ....
  26. pmc Behavioral therapies for drug abuse
    Kathleen M Carroll
    Department of Psychiatry, Yale University School of Medicine, 950 Campbell Ave 151D, West Haven, CT 06519, USA
    Am J Psychiatry 162:1452-60. 2005
    ..The authors review recent progress in strategies for the development of behavioral therapies for drug and alcohol abuse and dependence and discuss the range of effective behavioral therapies that are currently available...
  27. ncbi request reprint Contingency management to enhance naltrexone treatment of opioid dependence: a randomized clinical trial of reinforcement magnitude
    Kathleen M Carroll
    Department of Psychiatry, Division of Substance Abuse, Yale University School of Medicine, West Haven, Connecticut 06516, USA
    Exp Clin Psychopharmacol 10:54-63. 2002
    ..These findings suggest that targeted behavioral therapies can play a substantial role in broadening the utility of available pharmacotherapies...
  28. pmc MET meets the real world: design issues and clinical strategies in the Clinical Trials Network
    Kathleen M Carroll
    Department of Psychiatry, Yale University School of Medicine, West Haven, CT 06516, USA
    J Subst Abuse Treat 23:73-80. 2002
    ..Issues requiring attention included the diversity in treatments offered across sites, heterogeneity in the study sample, and training of clinicians drawn from the staff of community programs to deliver the study treatments...
  29. pmc Ten take home lessons from the first 10 years of the CTN and 10 recommendations for the future
    Kathleen M Carroll
    Division of Substance Abuse, Department of Psychiatry, Yale University School of Medicine, West Haven, CT, USA
    Am J Drug Alcohol Abuse 37:275-82. 2011
    ..The first 10 years of the National Institute on Drug Abuse's Clinical Trials Network (CTN) yielded a wealth of data on the effectiveness of a number of behavioral, pharmacological, and combined approaches in community-based settings...
  30. pmc Using the experience sampling method in the context of contingency management for substance abuse treatment
    Mathilde M Husky
    Yale University School of Medicine, USA
    J Appl Behav Anal 41:635-44. 2008
    ..It may also lead to the identification of new target behaviors for CM in the context of substance abuse treatment...
  31. ncbi request reprint Disulfiram treatment for cocaine dependence in methadone-maintained opioid addicts
    I L Petrakis
    Department of Psychiatry, Yale University, New Haven, Connecticut, USA
    Addiction 95:219-28. 2000
    ..We evaluated the efficacy of disulfiram for cocaine dependence, both with and without co-morbid alcohol abuse, in a group of methadone-maintained opioid addicts...
  32. ncbi request reprint Fluoxetine treatment of depressive disorders in methadone-maintained opioid addicts
    I Petrakis
    Department of Psychiatry, Yale University, New Haven, CT, USA
    Drug Alcohol Depend 50:221-6. 1998
    ..This study suggests that fluoxetine is not an effective agent in treating depression or cocaine use in this population...
  33. pmc Combining cognitive behavioral therapy with contingency management for smoking cessation in adolescent smokers: a preliminary comparison of two different CBT formats
    Dana A Cavallo
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06519, USA
    Am J Addict 16:468-74. 2007
    ..In addition, significantly more participants in the CBT group completed treatment. These preliminary results suggest that when combined with CM, the standard weekly format of CBT is more acceptable to adolescent smokers...
  34. pmc The alliance in motivational enhancement therapy and counseling as usual for substance use problems
    Paul Crits-Christoph
    Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Consult Clin Psychol 77:1125-35. 2009
    ..Implications of the findings for conceptualization of the alliance and for training of therapists are discussed...
  35. pmc Perspective is everything: the predictive validity of six working alliance instruments
    L R Fenton
    Division of Substance Abuse, Yale University School of Medicine, New Haven, CT, USA
    J Psychother Pract Res 10:262-8. 2001
    ....
  36. ncbi request reprint Manual-guided cognitive-behavioral therapy training: a promising method for disseminating empirically supported substance abuse treatments to the practice community
    J Morgenstern
    Mount Sinai School of Medicine, Department of Psychiatry, Box 1230, One Gustave L Levy Place, New York, New York 10029, USA
    Psychol Addict Behav 15:83-8. 2001
    ..Findings demonstrate the feasibility of using psychotherapy technology tools as a means of disseminating science-based treatments to the substance abuse practice community...
  37. pmc Evaluating motivational enhancement therapy adherence and competence among Spanish-speaking therapists
    Elizabeth J Santa Ana
    VA CT Healthcare System, Department of Psychiatry, 950 Campbell Avenue, West Haven, CT 06516, USA
    Drug Alcohol Depend 103:44-51. 2009
    ....
  38. ncbi request reprint Motivational interviewing with psychiatrically ill substance abusing patients
    S Martino
    Yale University School of Medicine, New Haven, Conn 06520 8038, USA
    Am J Addict 9:88-91. 2000
    ....
  39. pmc Evidence-based practices for substance use disorders
    Mark P McGovern
    Department of Psychiatry, Dartmouth Medical School, Lebanon, NH 03766, USA
    Psychiatr Clin North Am 26:991-1010. 2003
    ....
  40. pmc The cost-effectiveness of four treatments for marijuana dependence
    Todd A Olmstead
    University of Connecticut Health Center, Department of Psychiatry, Farmington, CT 06030 1410, USA
    Addiction 102:1443-53. 2007
    ..Costs were collected retrospectively from the provider and include the costs of therapy, patient drug testing, and those associated with the incentives component (value of vouchers, time to administer the voucher system)...
  41. pmc Single versus multiple drug focus in substance abuse clinical trials research
    Bruce J Rounsaville
    Department of Psychiatry, Division of Substance Abuse, Yale University, West Haven, CT 06516, USA
    Drug Alcohol Depend 70:117-25. 2003
    ..Although many treatment efficacy questions can best be answered by single focus studies, we recommend that such designs be adopted only after less restrictive designs are first considered...
  42. pmc Site matters: multisite randomized trial of motivational enhancement therapy in community drug abuse clinics
    Samuel A Ball
    Department of Psychiatry, Yale University School of Medicine, APT Foundation, New Haven, CT 06511, USA
    J Consult Clin Psychol 75:556-67. 2007
    ..An independent evaluation of session audiotapes indicated that MET and CAU were highly and comparably discriminable across sites...
  43. pmc Community program therapist adherence and competence in motivational enhancement therapy
    Steve Martino
    Yale University School of Medicine, Department of Psychiatry, Division of Substance Abuse, 950 Campbell Avenue, West Haven, CT 06516, USA
    Drug Alcohol Depend 96:37-48. 2008
    ....
  44. pmc What is usual about "treatment-as-usual"? Data from two multisite effectiveness trials
    Elizabeth J Santa Ana
    Department of Psychiatry, VA Connecticut Healthcare System, West Haven, CT 06516, USA
    J Subst Abuse Treat 35:369-79. 2008
    ..These data suggest missed opportunities for optimally engaging patients in the early stages of treatment and enhancing substance use outcomes and only moderate success to date of efforts to bridge the gap between research and practice...
  45. pmc Ethnic differences in substance abuse treatment retention, compliance, and outcome from two clinical trials
    Celeste O Milligan
    Psychiatry Department at Yale University School of Medicine, Clinical Research Unit, New Haven, Connecticut 06511, USA
    Psychiatr Serv 55:167-73. 2004
    ....
  46. pmc Pretreatment brain activation during stroop task is associated with outcomes in cocaine-dependent patients
    Judson A Brewer
    Yale University School of Medicine, Department of Psychiatry, Connecticut Mental Health Center, New Haven, CT 06519, USA
    Biol Psychiatry 64:998-1004. 2008
    ..No prior studies have systematically examined the neural correlates of cognitive control as related to treatment outcomes for cocaine dependence...
  47. pmc Informal discussions in substance abuse treatment sessions
    Steve Martino
    Division of Substance Abuse, Department of Psychiatry, Yale University School of Medicine, West Haven, CT 06516, USA
    J Subst Abuse Treat 36:366-75. 2009
    ....
  48. pmc Intention-to-treat meets missing data: implications of alternate strategies for analyzing clinical trials data
    Charla Nich
    Department of Psychiatry, Division of Substance Abuse, VA CT healthcare Center 1510, Yale University, 950 Campbell Avenue, West Haven, CT 06515, USA
    Drug Alcohol Depend 68:121-30. 2002
    ..Moreover, regardless of the strategy used, investigators should clearly describe their handling of data from participants who violate the protocol...
  49. ncbi request reprint Engaging young probation-referred marijuana-abusing individuals in treatment: a pilot trial
    Rajita Sinha
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Am J Addict 12:314-23. 2003
    ..Participants in both conditions reported significant reductions in marijuana use and improvement in legal problems. These findings suggest that young marijuana abusers benefit from scientifically validated treatments...
  50. pmc A randomized controlled trial of a money management-based substance use intervention
    Marc I Rosen
    Department of Veterans Affairs, Connecticut Healthcare System, West Haven, Connecticut, USA
    Psychiatr Serv 60:498-504. 2009
    ..In the advisor-teller money manager (ATM) intervention, a money manager stores patients' checkbooks and automated bank cards, trains patients to manage their own funds, and links spending to activities related to their treatment goals...
  51. pmc Quality versus quantity: acquisition of coping skills following computerized cognitive-behavioral therapy for substance use disorders
    Brian D Kiluk
    Division of Substance Abuse, Yale University School of Medicine, West Haven, CT 06516, USA
    Addiction 105:2120-7. 2010
    ..To evaluate the changes over time in quality and quantity of coping skills acquired following cognitive behavioral therapy (CBT), and examine potential mediating effects on substance use outcomes...
  52. pmc D-Cycloserine attenuates reactivity to smoking cues in nicotine dependent smokers: a pilot investigation
    Elizabeth J Santa Ana
    VA Connecticut Healthcare System, Department of Psychiatry, Division of Substance Abuse, West Haven, CT 06516, USA
    Drug Alcohol Depend 104:220-7. 2009
    ..These findings provide promising support for DCS combined with cue exposure therapy in attenuating conditioned reactivity to smoking cues...
  53. pmc Mindfulness training and stress reactivity in substance abuse: results from a randomized, controlled stage I pilot study
    Judson A Brewer
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
    Subst Abus 30:306-17. 2009
    ..This pilot study provides evidence of the feasibility of MT in treating SUDs and suggests that MT may be efficacious in targeting stress...
  54. pmc Systematic cultural adaptation of cognitive-behavioral therapy to reduce alcohol use among HIV-infected outpatients in western Kenya
    Rebecca K Papas
    Department of Medicine, Yale University School of Medicine, New Haven, CT, USA
    AIDS Behav 14:669-78. 2010
    ..PDA effect sizes (Cohen's d) between first and last CBT session were 2.32 (women) and 2.64 (men). Participants reported treatment satisfaction. Results indicate feasibility, acceptability and preliminary efficacy for CBT in Kenya...
  55. pmc Increased error-related thalamic activity during early compared to late cocaine abstinence
    Chiang Shan R Li
    Department of Psychiatry, Yale University, New Haven, CT 06519 USA
    Drug Alcohol Depend 109:181-9. 2010
    ..These findings support the hypothesis that heightened thalamic reactivity to salient stimuli co-occur with cocaine craving and loss of self control...
  56. pmc Cognitive function as an emerging treatment target for marijuana addiction
    Mehmet Sofuoglu
    Department of Psychiatry, Yale University School of Medicine, and VA Connecticut Healthcare System, West Haven, Connecticut 06516, USA
    Exp Clin Psychopharmacol 18:109-19. 2010
    ..Future clinical studies optimally designed to measure cognitive function as well as drug use behavior would be needed to test the efficacy of these treatments for marijuana addiction...
  57. ncbi request reprint The URICA as a measure of motivation to change among treatment-seeking individuals with concurrent alcohol and cocaine problems
    Michael V Pantalon
    Department of Psychiatry Division of Substance Abuse, Yale University School of Medicine, CMHC SAC S209, 34 Park Street, New Haven, Connecticut 06519, USA
    Psychol Addict Behav 16:299-307. 2002
    ....
  58. pmc Correspondence of motivational enhancement treatment integrity ratings among therapists, supervisors, and observers
    Steve Martino
    Department of Psychiatry, Yale University School ofMedicine, VA Connecticut Healthcare System, 950 Campbell Avenue 151 D, West Haven, CT 06516, USA
    Psychother Res 19:181-93. 2009
    ....
  59. ncbi request reprint A randomized controlled pilot study of motivational interviewing for patients with psychotic and drug use disorders
    Steve Martino
    Yale Psychosocial Substance Abuse Research Center and Yale University School of Medicine, West Haven, CT 06516, USA
    Addiction 101:1479-92. 2006
    ..This pilot study examined the efficacy of a two-session motivational interview adapted for dually diagnosed psychotic and drug-related disordered patients (DDMI) in comparison to a two-session standard psychiatric interview (SI)...
  60. pmc Millon Clinical Multiaxial Inventory-III subtypes of opioid dependence: validity and matching to behavioral therapies
    Samuel A Ball
    Department of Psychiatry, Yale University School of Medicine, West Haven, CT 06516, USA
    J Consult Clin Psychol 72:698-711. 2004
    ..Predictive validity analyses indicated less symptom improvement for the higher problem subtypes, and patient treatment matching analyses indicated that some subtypes had better outcomes in the no-incentive voucher conditions...
  61. pmc Neurocognitive indicators predict results of an informed-consent quiz among substance-dependent treatment seekers entering a randomized clinical trial
    Brian D Kiluk
    Department of Psychiatry, Division of Substance Abuse, Yale University School of Medicine, 950 Campbell Avenue, 151D, West Haven, Connecticut 06516, USA
    J Stud Alcohol Drugs 71:704-12. 2010
    ....
  62. pmc Sex differences in cocaine-dependent individuals' response to disulfiram treatment
    Charla Nich
    Yale University School of Medicine, VA Connecticut Health Care System, West Haven, USA
    Addict Behav 29:1123-8. 2004
    ..Reasons for this apparent sex-based response are not clear, but possible mechanisms worthy of greater study include differences in alcohol use by sex as well as differences in dopamine-mediated responses to cocaine and disulfiram...
  63. pmc Behavioral impulsivity predicts treatment outcome in a smoking cessation program for adolescent smokers
    Suchitra Krishnan-Sarin
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, 34 Park Street, New Haven, CT 06519, USA
    Drug Alcohol Depend 88:79-82. 2007
    ..To examine the relationship between impulsivity and smoking cessation treatment response among adolescents...
  64. ncbi request reprint Methadone versus buprenorphine with contingency management or performance feedback for cocaine and opioid dependence
    Richard S Schottenfeld
    Department of Psychiatry, Yale University School of Medicine, 34 Park St, Rm S204, New Haven, CT 06519, USA
    Am J Psychiatry 162:340-9. 2005
    ..This study compares effects of buprenorphine and methadone and evaluates the efficacy of combining contingency management with maintenance treatment for patients with co-occurring cocaine and opioid dependence...
  65. ncbi request reprint Contingency management treatments: Reinforcing abstinence versus adherence with goal-related activities
    Nancy M Petry
    Department of Psychiatry, University of Connecticut Health Center, Storrs, CT 06030 3944, USA
    J Consult Clin Psychol 74:592-601. 2006
    ..Abstinence at 6- and 9-month follow-ups did not differ by group, but longest duration of abstinence achieved during treatment was associated with abstinence posttreatment...
  66. ncbi request reprint Differences in treatment outcome between male alcohol dependent offenders of domestic violence with and without positive drug screens
    Caroline J Easton
    Department of Psychiatry, Division of Substance Abuse, Yale University School of Medicine SATU, Box 18, 1 Long Wharf, New Haven, CT 06511, USA
    Addict Behav 32:2151-63. 2007
    ..The findings suggest that alcohol dependent men who continue to use illicit drugs may require additional interventions to effectively control their drug use and, their anger management styles...
  67. ncbi request reprint Treatment retention and outcome among cocaine-dependent patients with and without active criminal justice involvement
    Caroline J Easton
    Division of Substance Abuse, ASAP SATU, Box 18, 1 Long Wharf, New Haven, CT 06511, USA
    J Am Acad Psychiatry Law 35:83-91. 2007
    ....
  68. pmc Enhancing brief cognitive-behavioral therapy with motivational enhancement techniques in cocaine users
    Sherry A McKee
    Yale University School of Medicine, Department of Psychiatry, New Haven, CT 06519, USA
    Drug Alcohol Depend 91:97-101. 2007
    ..We investigated the impact of enhancing brief cognitive-behavioral therapy with motivational interviewing techniques for cocaine abuse or dependence, using a focused intervention paradigm...
  69. ncbi request reprint Reasons for dropout from drug abuse treatment: symptoms, personality, and motivation
    Samuel A Ball
    Yale University School of Medicine, Department of Psychiatry, Division of Substance Abuse, United States VA Connecticut Healthcare System, West Haven, CT 06516, United States
    Addict Behav 31:320-30. 2006
    ..Results from this preliminary evaluation will guide the development of an instrument and intervention focused on dropout risk factors and treatment reengagement...
  70. ncbi request reprint A cognitive behavioral therapy for alcohol-dependent domestic violence offenders: an integrated substance abuse-domestic violence treatment approach (SADV)
    Caroline J Easton
    Department of Psychiatry, Division of Substance Abuse, Yale University School of Medicine SATU, 1 Long Wharf, New Haven, CT 06511, USA
    Am J Addict 16:24-31. 2007
    ..These data suggest the promise of the SADV group therapy approach for alcohol-dependent males with a history of IPV who present for substance abuse treatment...
  71. pmc Teaching community program clinicians motivational interviewing using expert and train-the-trainer strategies
    Steve Martino
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Addiction 106:428-41. 2011
    ..The effectiveness of expert-led (EX) and train-the-trainer (TT) strategies was compared to a self-study approach (SS) for teaching clinicians motivational interviewing (MI)...
  72. pmc Neuroscience of behavioral and pharmacological treatments for addictions
    Marc N Potenza
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Neuron 69:695-712. 2011
    ..We then propose new directions for treatment development and targets that are informed by recent evidence regarding the heterogeneity of addictions and the neurobiological contributions to these disorders...
  73. pmc Galantamine improves sustained attention in chronic cocaine users
    Mehmet Sofuoglu
    Yale University, School of Medicine, Department of Psychiatry, VA Connecticut Healthcare System, 950 Campbell Avenue, Bldg 36 116A4, West Haven, CT 06516, USA
    Exp Clin Psychopharmacol 19:11-9. 2011
    ..g., sustained attention) in abstinent cocaine users. The potential efficacy of galantamine as a treatment for cocaine abuse needs to be further evaluated in clinical trials...
  74. pmc Relationship of cognitive function and the acquisition of coping skills in computer assisted treatment for substance use disorders
    Brian D Kiluk
    Division of Substance Abuse, Yale University School of Medicine, West Haven, CT 06516, USA
    Drug Alcohol Depend 114:169-76. 2011
    ..Little previous research has examined the cognitive or neuropsychological factors that may affect substance users' ability to learn new coping skills in CBT...
  75. pmc Coping strategy use following computerized cognitive-behavioral therapy for substance use disorders
    Dawn E Sugarman
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06516, USA
    Psychol Addict Behav 24:689-95. 2010
    ....
  76. ncbi request reprint Primary care-based ambulatory opioid detoxification: the results of a clinical trial
    M E Waugh
    Department of Medicine, Yale University School of Medicine, New Haven, Connecticut 06520-8025, USA
    J Gen Intern Med 10:255-60. 1995
    ..Ambulatory opioid detoxification can give internists a larger role in initiating drug treatment for IDUs who are addicted to opioids...
  77. pmc Prize reinforcement contingency management for treating cocaine users: how low can we go, and with whom?
    Nancy M Petry
    University of Connecticut Health Center, Farmington, CT, USA
    Addiction 99:349-60. 2004
    ..This study evaluated the efficacy of a low-cost, prize reinforcement contingency management (CM) intervention for reducing cocaine use...
  78. ncbi request reprint Tailoring cannabis dependence treatment for a diverse population
    Karen L Steinberg
    Department of Psychiatry, University of Connecticut Medical School, Farmington, CT 06030 1410, USA
    Addiction 97:135-42. 2002
    ..This paper will describe the clinical interventions used with the MTP participants, the theoretical rationale guiding their design and practical aspects related to implementation and treatment response...
  79. ncbi request reprint Clinical and translational research: introduction to the special issue
    Edward V Nunes
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, USA
    Exp Clin Psychopharmacol 10:155-8. 2002
    ....
  80. pmc We don't train in vain: a dissemination trial of three strategies of training clinicians in cognitive-behavioral therapy
    Diane E Sholomskas
    Applied Behavioral Research, New Haven, CT, USA
    J Consult Clin Psychol 73:106-15. 2005
    ..Statistically significant differences favoring the seminar plus supervision over the manual only condition were found for adherence and skill ratings for 2 of the 3 role plays, with intermediate scores for the Web condition...
  81. ncbi request reprint Psychosis induced by smoking cessation clinic administered anticholinergic overload
    Laura A Clarke
    Department of Psychiatry, New York University, New York, New York, USA
    Ann Clin Psychiatry 16:171-5. 2004
    ..We will review the literature regarding previous cases of anticholinergic medication induced psychosis, discuss treatment options and review the clinical effects of anticholinergic medications...
  82. pmc One small step for manuals: Computer-assisted training in twelve-step facilitation
    Diane E Sholomskas
    Applied Behavioral Research, New Haven, Connecticut, USA
    J Stud Alcohol 67:939-45. 2006
    ....
  83. pmc White matter integrity is associated with treatment outcome measures in cocaine dependence
    Jiansong Xu
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, New Haven, CT 06519, USA
    Neuropsychopharmacology 35:1541-9. 2010
    ..The findings of an association between better WM integrity at treatment onset and longer abstinence suggest that strategies for improving WM integrity warrant consideration in developing new interventions for cocaine dependence...
  84. pmc Issues in designing and implementing a Spanish-language multi-site clinical trial
    Lourdes Suarez-Morales
    Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    Am J Addict 16:206-15. 2007
    ..To encourage similar research, strategies are described that were developed by the study team to meet these challenges...
  85. pmc Cost effectiveness of disulfiram: treating cocaine use in methadone-maintained patients
    Mireia Jofre-Bonet
    ICEH London School of Hygiene and Tropical Medicine, Keppel Street, Room 9 311, London WC1E 7HT, UK
    J Subst Abuse Treat 26:225-32. 2004
    ....
  86. pmc Contingency Management to reduce substance use in individuals who are homeless with co-occurring psychiatric disorders
    Kathlene Tracy
    New York University School of Medicine, New York, NY 10032, USA
    Am J Drug Alcohol Abuse 33:253-8. 2007
    ..This pilot trial suggests that application of low-cost CM procedures is feasible within this novel setting and may decrease substance use...
  87. ncbi request reprint Disulfiram, cocaine, and alcohol: two outcomes for the price of one?
    Michael Gossop
    Alcohol Alcohol 41:119-20. 2006
  88. ncbi request reprint Client satisfaction with three therapies in the treatment of alcohol dependence: results from project MATCH
    Dennis M Donovan
    Alcohol and Drug Abuse Institute, Department of Psychiatry and Behavioral Sciences, University of Washington, 1107 NE 45th Street, Suite 120, Seattle, WA 98105 4631, USA
    Am J Addict 11:291-307. 2002
    ..The results reflect the complexity of the relationship among treatment process, therapy outcome, and client satisfaction...
  89. ncbi request reprint Only connect?
    Kathleen M Carroll
    Addiction 100:267-8. 2005
  90. ncbi request reprint The effects of gender, age, ethnicity, and liver cirrhosis on cytochrome P450 enzyme activity in human liver microsomes and inducibility in cultured human hepatocytes
    Andrew Parkinson
    XenoTech, LLC, Lenexa, KS 66219, USA
    Toxicol Appl Pharmacol 199:193-209. 2004
    ..This review summarizes these findings and discusses their implications for the use of human liver microsomes and hepatocytes for in vitro studies of drug metabolism and enzyme induction, which play a key role in drug development...
  91. ncbi request reprint Effects of prototypical microsomal enzyme inducers on cytochrome P450 expression in cultured human hepatocytes
    Ajay Madan
    XenoTech, LLC, 16825 West 116th Street, Lenexa, KS 66219, USA
    Drug Metab Dispos 31:421-31. 2003
    ....

Research Grants15

  1. Computer-Based Training in Cognitve Behavioral Therapy
    Kathleen Carroll; Fiscal Year: 2002
    ..The patients' ability to demonstrate coping skills through a role-play evaluation will be a secondary outcome. A six-month follow-up will assess durability and/or delayed emergence of effects. ..
  2. Maximizing CBT's Efficacy with Medication & CM
    Kathleen Carroll; Fiscal Year: 2009
    ..Variables assessing theoretical mechanisms of action will be assessed monthly during treatment. ..
  3. Maximizing CBT's Efficacy with Medication & CM
    Kathleen Carroll; Fiscal Year: 2006
    ..Variables assessing theoretical mechanisms of action will be assessed monthly during treatment. ..
  4. Maximizing CBT's Efficacy with Medication & CM
    Kathleen Carroll; Fiscal Year: 2007
    ..Variables assessing theoretical mechanisms of action will be assessed monthly during treatment. ..
  5. CLINICAL TRIALS NETWORK: NEW ENGLAND NODE
    Kathleen Carroll; Fiscal Year: 2006
    ....
  6. Maximizing Effectiveness of Cognitive Behavior Therapy and Contingency Management
    Kathleen Carroll; Fiscal Year: 2007
    ..Study treatments will last 12 weeks. Primary outcomes will be percent days abstinent and results of urine toxicology screens. ..
  7. Computer-Based Training in Cognitve Behavioral Therapy
    Kathleen Carroll; Fiscal Year: 2007
    ..abstract_text> ..
  8. CLINICAL TRIALS NETWORK: NEW ENGLAND NODE
    Kathleen Carroll; Fiscal Year: 2007
    ....
  9. PSYCHOTHERAPY OF SUBSTANCE USE DISORDERS
    Kathleen Carroll; Fiscal Year: 2007
    ..To maximize the effectiveness and durability of CM for abstinence, we will evaluate the benefit of integrating CM with skills training specifically designed to reduce drop-off of CM's benefits. ..
  10. CLINICAL TRIALS NETWORK: NEW ENGLAND NODE
    Kathleen Carroll; Fiscal Year: 2005
    ....
  11. Computer-based Training in Cognitive Behavioral Therapy: Web-based delivery of CB
    Kathleen M Carroll; Fiscal Year: 2011
    ....