S Caprio

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi request reprint Intrahepatic fat accumulation and alterations in lipoprotein composition in obese adolescents: a perfect proatherogenic state
    Anna M G Cali
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Diabetes Care 30:3093-8. 2007
  2. pmc Utility of hemoglobin A(1c) for diagnosing prediabetes and diabetes in obese children and adolescents
    Paulina Nowicka
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA
    Diabetes Care 34:1306-11. 2011
  3. pmc The triglyceride-to-HDL cholesterol ratio: association with insulin resistance in obese youths of different ethnic backgrounds
    Cosimo Giannini
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT, USA
    Diabetes Care 34:1869-74. 2011
  4. pmc Cellularity and adipogenic profile of the abdominal subcutaneous adipose tissue from obese adolescents: association with insulin resistance and hepatic steatosis
    Romy Kursawe
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA
    Diabetes 59:2288-96. 2010
  5. pmc Central role of fatty liver in the pathogenesis of insulin resistance in obese adolescents
    Ebe D'Adamo
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA
    Diabetes Care 33:1817-22. 2010
  6. pmc Interethnic differences in muscle, liver and abdominal fat partitioning in obese adolescents
    David Liska
    Department of Pediatrics, Internal Medicine, the Howard Hughes Institute, and the General Clinical Research Center of the Yale University School of Medicine, New Haven, Connecticut, United States of America
    PLoS ONE 2:e569. 2007
  7. pmc Circulating levels of FGF-21 in obese youth: associations with liver fat content and markers of liver damage
    Cosimo Giannini
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Clin Endocrinol Metab 98:2993-3000. 2013
  8. pmc The association between hepatic fat content and liver injury in obese children and adolescents: effects of ethnicity, insulin resistance, and common gene variants
    Nicola Santoro
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT, USA
    Diabetes Care 36:1353-60. 2013
  9. doi request reprint Development of type 2 diabetes mellitus in the obese adolescent: a growing challenge
    Sonia Caprio
    Department of Pediatrics, Yale Clinical Center Investigation, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Endocr Pract 18:791-5. 2012
  10. pmc Decreased transcription of ChREBP-α/β isoforms in abdominal subcutaneous adipose tissue of obese adolescents with prediabetes or early type 2 diabetes: associations with insulin resistance and hyperglycemia
    Romy Kursawe
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA
    Diabetes 62:837-44. 2013

Research Grants

Collaborators

Detail Information

Publications56

  1. ncbi request reprint Intrahepatic fat accumulation and alterations in lipoprotein composition in obese adolescents: a perfect proatherogenic state
    Anna M G Cali
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Diabetes Care 30:3093-8. 2007
    ..Therefore, our objective was to determine the effect of hepatic steatosis on lipoprotein concentration and size in obese adolescents...
  2. pmc Utility of hemoglobin A(1c) for diagnosing prediabetes and diabetes in obese children and adolescents
    Paulina Nowicka
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA
    Diabetes Care 34:1306-11. 2011
    ..This recommendation is based on data in adults showing the relationship between A1C with future development of diabetes and microvascular complications. However, studies in the pediatric population are lacking...
  3. pmc The triglyceride-to-HDL cholesterol ratio: association with insulin resistance in obese youths of different ethnic backgrounds
    Cosimo Giannini
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT, USA
    Diabetes Care 34:1869-74. 2011
    ..We evaluated whether the triglyceride-to-HDL cholesterol (TG/HDL-C) ratio is associated with insulin resistance (IR) in a large multiethnic cohort of obese youths...
  4. pmc Cellularity and adipogenic profile of the abdominal subcutaneous adipose tissue from obese adolescents: association with insulin resistance and hepatic steatosis
    Romy Kursawe
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA
    Diabetes 59:2288-96. 2010
    ....
  5. pmc Central role of fatty liver in the pathogenesis of insulin resistance in obese adolescents
    Ebe D'Adamo
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA
    Diabetes Care 33:1817-22. 2010
    ....
  6. pmc Interethnic differences in muscle, liver and abdominal fat partitioning in obese adolescents
    David Liska
    Department of Pediatrics, Internal Medicine, the Howard Hughes Institute, and the General Clinical Research Center of the Yale University School of Medicine, New Haven, Connecticut, United States of America
    PLoS ONE 2:e569. 2007
    ..Thus, irrespective of obesity, there seem to be some clear ethnic differences in the amount of lipid accumulated in skeletal muscle, liver and abdominal cavity...
  7. pmc Circulating levels of FGF-21 in obese youth: associations with liver fat content and markers of liver damage
    Cosimo Giannini
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Clin Endocrinol Metab 98:2993-3000. 2013
    ..5% and HFF% ≥ 5.5%, respectively) and explored their relationship with hepatic fat content, measures of hepatic apoptosis, and insulin sensitivity...
  8. pmc The association between hepatic fat content and liver injury in obese children and adolescents: effects of ethnicity, insulin resistance, and common gene variants
    Nicola Santoro
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT, USA
    Diabetes Care 36:1353-60. 2013
    ....
  9. doi request reprint Development of type 2 diabetes mellitus in the obese adolescent: a growing challenge
    Sonia Caprio
    Department of Pediatrics, Yale Clinical Center Investigation, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Endocr Pract 18:791-5. 2012
    ..To describe the metabolic phenotype of type 2 diabetes mellitus in youth and possible metabolic defects leading to its development with particular emphasis on fatty liver...
  10. pmc Decreased transcription of ChREBP-α/β isoforms in abdominal subcutaneous adipose tissue of obese adolescents with prediabetes or early type 2 diabetes: associations with insulin resistance and hyperglycemia
    Romy Kursawe
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA
    Diabetes 62:837-44. 2013
    ..In conclusion, early in the development of prediabetes/type 2 diabetes in youth, ChREBPβ expression in adipose tissue predicts insulin resistance and, therefore, might play a role in the regulation of glucose tolerance...
  11. pmc Longitudinal effects of MRI-measured hepatic steatosis on biomarkers of glucose homeostasis and hepatic apoptosis in obese youth
    Grace Kim
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT, USA
    Diabetes Care 36:130-6. 2013
    ..We used fast-gradient magnetic resonance imaging (MRI) to determine the longitudinal associations between the hepatic fat content (HFF), glucose homeostasis, and a biomarker of hepatocellular apoptosis in obese youth...
  12. pmc Evidence for early defects in insulin sensitivity and secretion before the onset of glucose dysregulation in obese youths: a longitudinal study
    Cosimo Giannini
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA
    Diabetes 61:606-14. 2012
    ..Across rising categories of normal 2-h glucose levels, NGT obese adolescents exhibit significant impairment of β-cell function relative to insulin sensitivity associated with the development of IGT...
  13. ncbi request reprint The metabolic phenotype of pre-diabetes in obese youth
    S Caprio
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 208064, USA
    Nutr Metab Cardiovasc Dis 14:270-5. 2004
  14. ncbi request reprint Definitions and pathophysiology of the metabolic syndrome in obese children and adolescents
    S Caprio
    Yale University, New Haven, CT, USA
    Int J Obes (Lond) 29:S24-5. 2005
  15. ncbi request reprint The metabolic consequences of childhood obesity
    Ram Weiss
    Department of Pediatrics and the Children s General Clinical Research Center, Yale University School of Medicine, P O Box 802064, New Haven, CT 06520, USA
    Best Pract Res Clin Endocrinol Metab 19:405-19. 2005
    ..The long-term impact on cardiovascular and liver morbidity of obesity-related insulin resistance in young people is expected to emerge as these youngsters become young adults...
  16. ncbi request reprint Metabolic impact of obesity in childhood
    S Caprio
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA
    Endocrinol Metab Clin North Am 28:731-47. 1999
    ..These observations underscore the need for research efforts directed at the development of effective interventions to stem the tide of the childhood obesity epidemic...
  17. ncbi request reprint Insulin resistance in childhood obesity
    Sonia Caprio
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06510, USA
    J Pediatr Endocrinol Metab 15:487-92. 2002
    ....
  18. doi request reprint Treatment of impaired glucose tolerance in childhood
    Sonia Caprio
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520 8064, USA
    Nat Clin Pract Endocrinol Metab 4:320-1. 2008
  19. ncbi request reprint Insulin: the other anabolic hormone of puberty
    S Caprio
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA
    Acta Paediatr Suppl 88:84-7. 1999
    ..Thus, we postulate that the insulin resistance of puberty induces compensatory hyperinsulinaemia, which in turn suppresses circulating levels of IGFBP-1, which in turn leads to increased levels of free IGF-1...
  20. ncbi request reprint Microalbuminuria in pediatric obesity: prevalence and relation to other cardiovascular risk factors
    T S Burgert
    Department of Pediatrics and the General Clinical Research Center, Yale University School of Medicine, New Haven 06520, USA
    Int J Obes (Lond) 30:273-80. 2006
    ..While the mechanisms behind this association remain to be established, most studies suggest that MA is the result of increased vascular leakage denoting endothelial dysfunction associated with early vasculopathy...
  21. ncbi request reprint Ethnic differences in beta cell adaptation to insulin resistance in obese children and adolescents
    R Weiss
    Department of Pediatrics, Yale University School of Medicine, 333 Cedar Street, New Haven, P O Box 208064, CT 06520, USA
    Diabetologia 49:571-9. 2006
    ..The aim of this study was to evaluate the early insulin response and insulin clearance in response to an oral glucose load in obese children and adolescents...
  22. doi request reprint Islet function in obese adolescents
    C Giannini
    Department of Pediatrics, Yale School of Medicine and Yale Center for Clinical Investigation, Yale University, New Haven, CT 06520, USA
    Diabetes Obes Metab 14:40-5. 2012
    ..In this review, we have sought to mainly describe the role of β-cell function in relation to the ambient insulin resistance in the development of T2D in obese adolescents...
  23. ncbi request reprint Importance of plasma leptin in predicting future weight gain in obese children: a two-and-a-half-year longitudinal study
    M Savoye
    Department of Pediatrics and The Children s General Clinical Research Center and the Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Int J Obes Relat Metab Disord 26:942-6. 2002
    ..To determine whether relatively low leptin levels predict changes in adiposity in prepubertal and pubertal obese children...
  24. doi request reprint High normal fasting glucose level in obese youth: a marker for insulin resistance and beta cell dysregulation
    G O'Malley
    Department of Pediatrics, Yale University School of Medicine, 330 Cedar Street, PO Box 208064, New Haven, CT 06520, USA
    Diabetologia 53:1199-209. 2010
    ..We investigated whether normal fasting plasma glucose levels (<5.60 mmol/l) are associated with decreases in insulin sensitivity and beta cell function, as well as an adverse cardiovascular profile in obese youth...
  25. ncbi request reprint Temporal patterns of circulating leptin levels in lean and obese adolescents: relationships to insulin, growth hormone, and free fatty acids rhythmicity
    R Heptulla
    Department of Pediatrics and the Yale Children's Clinical Research Center, Yale University School of Medicine, New Haven, Connecticut 06510, USA
    J Clin Endocrinol Metab 86:90-6. 2001
    ..The nocturnal rise in leptin was paralleled by a nocturnal rise in GH and FFA levels. Additional studies are needed to test the potential link between the adipose-derived peptide and GH axis in humans...
  26. doi request reprint Prediabetes and type 2 diabetes in youth: an emerging epidemic disease?
    Anna Mg Cali
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Curr Opin Endocrinol Diabetes Obes 15:123-7. 2008
    ..Moreover, these co-morbidities persist into adulthood...
  27. ncbi request reprint Confronting the epidemic of childhood obesity
    Sonia Caprio
    Section of Pediatric Endocrinology, Department of Pediatrics, Yale University School of Medicine, PO Box 208081, New Haven, CT 06520 8081, USA
    Pediatrics 115:494-5. 2005
  28. ncbi request reprint The normal glucose tolerance continuum in obese youth: evidence for impairment in beta-cell function independent of insulin resistance
    Catherine W Yeckel
    Yale University School of Medicine, Department of Pediatrics, P O Box 802064, New Haven, Connecticut 06520, USA
    J Clin Endocrinol Metab 90:747-54. 2005
    ..005). Increased 2-h plasma glucose within the range of normal glucose tolerance in obese youth is associated with a specific impairment of beta-cell responsiveness distinct from the deterioration of insulin sensitivity...
  29. ncbi request reprint Obesity and the metabolic syndrome in children and adolescents
    Ram Weiss
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520, USA
    N Engl J Med 350:2362-74. 2004
    ....
  30. ncbi request reprint Validation of insulin sensitivity indices from oral glucose tolerance test parameters in obese children and adolescents
    Catherine W Yeckel
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Clin Endocrinol Metab 89:1096-101. 2004
    ..74 and -0.71; P < 0.0001), a tissue marker for insulin resistance. Insulin sensitivity can be estimated using plasma glucose and insulin responses derived from the OGTT in obese youth with normal and impaired glucose tolerance...
  31. ncbi request reprint Alanine aminotransferase levels and fatty liver in childhood obesity: associations with insulin resistance, adiponectin, and visceral fat
    Tania S Burgert
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Clin Endocrinol Metab 91:4287-94. 2006
    ..Nevertheless, the complete metabolic phenotype associated with abnormalities in biomarkers of liver injury and intrahepatic fat accumulation remains to be established...
  32. pmc Prediabetes in obese youth: a syndrome of impaired glucose tolerance, severe insulin resistance, and altered myocellular and abdominal fat partitioning
    Ram Weiss
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520, USA
    Lancet 362:951-7. 2003
    ..We investigated whether altered partitioning of myocellular and abdominal fat relates to abnormalities in glucose homoeostasis in obese adolescents with prediabetes...
  33. ncbi request reprint Low adiponectin levels in adolescent obesity: a marker of increased intramyocellular lipid accumulation
    Ram Weiss
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Clin Endocrinol Metab 88:2014-8. 2003
    ..The putative modulatory effects of adiponectin on insulin sensitivity may, in part, be mediated via its effects on IMCL lipid content...
  34. ncbi request reprint In situ evidence that peripheral insulin resistance in adolescents with poorly controlled type 1 diabetes is associated with impaired suppression of lipolysis: a microdialysis study
    Rubina A Heptulla
    Department of Pediatrics, Baylor College of Medicine, Clinical Care Center, Houston, TX 77030 2399, USA
    Pediatr Res 53:830-5. 2003
    ..63, p < 0.01). Our data suggest that failure of insulin to inhibit lipolysis in muscle and adipose tissue contributes to the severe peripheral insulin resistance that characterizes poorly controlled T1DM during adolescence...
  35. ncbi request reprint Do sensor glucose levels accurately predict plasma glucose concentrations during hypoglycemia and hyperinsulinemia?
    Teresa P Monsod
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Diabetes Care 25:889-93. 2002
    ....
  36. ncbi request reprint Assessment of skeletal muscle triglyceride content by (1)H nuclear magnetic resonance spectroscopy in lean and obese adolescents: relationships to insulin sensitivity, total body fat, and central adiposity
    Ranjana Sinha
    Department of Pediatrics, The Children s General Clinical Research Center at Yale University School of Medicine, New Haven, Connecticut 06510, USA
    Diabetes 51:1022-7. 2002
    ..The striking relationships between both IMCL and EMCL with insulin sensitivity in childhood suggest that these findings are not a consequence of aging but occur early in the natural course of obesity...
  37. ncbi request reprint Prevalence of impaired glucose tolerance among children and adolescents with marked obesity
    Ranjana Sinha
    Department of Pediatrics, Yale University School of Medicine, New Haven, Conn 06520, USA
    N Engl J Med 346:802-10. 2002
    ..We determined the prevalence of impaired glucose tolerance in a multiethnic cohort of 167 obese children and adolescents...
  38. pmc Comparative MR study of hepatic fat quantification using single-voxel proton spectroscopy, two-point dixon and three-point IDEAL
    Hyeonjin Kim
    Diagnostic Radiology, Yale University School of Medicine, New Haven, Connecticut 06520 8043, USA
    Magn Reson Med 59:521-7. 2008
    ..Therefore, protocol-specific establishment of cutoffs for liver fat content may be necessary...
  39. pmc Metabolic abnormalities underlying the different prediabetic phenotypes in obese adolescents
    Anna M G Cali'
    Yale University School of Medicine, Department of Pediatrics, 330 Cedar Street, New Haven, CT 06520, USA
    J Clin Endocrinol Metab 93:1767-73. 2008
    ..The aim of this study was to define the metabolic abnormalities underlying the prediabetic status of isolated impaired fasting glucose (IFG), isolated impaired glucose tolerance (IGT), and combined IFG/IGT in obese youth...
  40. ncbi request reprint High visceral and low abdominal subcutaneous fat stores in the obese adolescent: a determinant of an adverse metabolic phenotype
    Sara E Taksali
    Department of Pediatrics, Yale University School of Medicine, 333 Cedar Street, P O Box 208064, New Haven, CT 06520, USA
    Diabetes 57:367-71. 2008
    ....
  41. ncbi request reprint The "obese insulin-sensitive" adolescent: importance of adiponectin and lipid partitioning
    Ram Weiss
    Department of Pediatrics, Yale University School of Medicine, 333 Cedar Street, P O Box 208064, New Haven, Connecticut 06520, USA
    J Clin Endocrinol Metab 90:3731-7. 2005
    ..Obese insulin-sensitive adolescents are characterized by lower lipid deposition in the intramyocellular and visceral compartments and greater levels of adiponectin, despite similar degree of adiposity...
  42. ncbi request reprint Altered glucose metabolism in obese youth
    Ram Weiss
    Department of Pediatrics of the Yale University School of Medicine, CT 06520, USA
    Pediatr Endocrinol Rev 3:233-8. 2006
    ..The dynamics of glucose tolerance status in these youngsters seems to be more rapid than in adults, thus representing a narrow window of opportunity for successful intervention to prevent diabetes...
  43. ncbi request reprint Development of type 2 diabetes in children and adolescents
    Ram Weiss
    Curr Diab Rep 6:182-7. 2006
    ..Insufficient beta-cell compensation promotes altered glucose metabolism...
  44. ncbi request reprint Predictors of changes in glucose tolerance status in obese youth
    Ram Weiss
    Yale University School of Medicine, Department of Pediatrics, P O Box 802064, New Haven, CT 06520, USA
    Diabetes Care 28:902-9. 2005
    ..Type 2 diabetes in obese youth is an emerging problem. The metabolic and anthropometric predictors of change in glucose tolerance status in obese youth are unknown...
  45. ncbi request reprint Adiponectin in childhood and adolescent obesity and its association with inflammatory markers and components of the metabolic syndrome
    Jeffrey C Winer
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Clin Endocrinol Metab 91:4415-23. 2006
    ..Hypoadiponectinemia may contribute to the low-grade systemic chronic inflammatory state associated with childhood obesity...
  46. pmc Obesity and sex steroid changes across puberty: evidence for marked hyperandrogenemia in pre- and early pubertal obese girls
    Christopher R McCartney
    Center for Research in Reproduction, Box 800391, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    J Clin Endocrinol Metab 92:430-6. 2007
    ..Peripubertal obesity is associated with abnormal sex steroid concentrations, but the timing of onset and degree of these abnormalities remain unclear...
  47. ncbi request reprint Degree of obesity and glucose allostasis are major effectors of glucose tolerance dynamics in obese youth
    Ram Weiss
    Department of Pediatric Endocrinology, Yale University School of Medicine, New Haven, Connecticut, USA
    Diabetes Care 30:1845-50. 2007
    ..We examined whether glucose allostasis can be demonstrated using oral glucose tolerance tests (OGTTs) and the effects of the dynamics of beta-cell demand on longitudinal changes of glucose tolerance in obese youth...
  48. ncbi request reprint The metabolic syndrome in children and adolescents
    Paul Zimmet
    International Diabetes Institute, Melbourne, Vic, Australia
    Lancet 369:2059-61. 2007
  49. ncbi request reprint Anthropometric and psychosocial changes in obese adolescents enrolled in a Weight Management Program
    Mary Savoye
    Department of Pediatric Endocrinology and General Clinical Research Center, Yale University School of Medicine, New Haven, CT 06520 8064, USA
    J Am Diet Assoc 105:364-70. 2005
    ..To determine short- and long-term effects of the Bright Bodies Weight Management Program on obese adolescents and to further observe if a diet or nondiet approach is more successful...
  50. ncbi request reprint Effects of a weight management program on body composition and metabolic parameters in overweight children: a randomized controlled trial
    Mary Savoye
    Yale Center for Clinical Investigation, Yale University School of Medicine, New Haven, CT 06520, USA
    JAMA 297:2697-704. 2007
    ..Since most overweight children become overweight adults, this chronic condition results in serious metabolic complications by early adulthood. To curtail this major health issue, effective pediatric interventions are essential...
  51. ncbi request reprint The metabolic syndrome in children and adolescents - an IDF consensus report
    Paul Zimmet
    International Diabetes Institute, Melbourne, Victoria, Australia
    Pediatr Diabetes 8:299-306. 2007
  52. ncbi request reprint Beta-cell function across the spectrum of glucose tolerance in obese youth
    Ram Weiss
    Department of Pediatrics, Yale University School of Medicine, 333 Cedar St, P O Box 208064, New Haven, CT 06520, USA
    Diabetes 54:1735-43. 2005
    ..Obese youth with IGT have a significant defect in first-phase insulin secretion, while a defect in second-phase secretion and proinsulin processing is specific for type 2 diabetes in this age-group...
  53. ncbi request reprint A tale of twins and insulin resistance
    Ram Weiss
    J Pediatr 144:567-8. 2004
  54. doi request reprint Sleep-disordered breathing in children with metabolic syndrome: the role of leptin and sympathetic nervous system activity and the effect of continuous positive airway pressure
    Neal Nakra
    Yale University School of Medicine, Department of Pediatrics, Section of Respiratory Medicine, 333 Cedar St, Fitkin 510, New Haven, CT 06520, USA
    Pediatrics 122:e634-42. 2008
    ....
  55. ncbi request reprint Treating child obesity and associated medical conditions
    Sonia Caprio
    Yale University School of Medicine, USA
    Future Child 16:209-24. 2006
    ..Caprio argues that obesity should be recognized as a disease and receive coverage for its treatment just as other diseases do...

Research Grants33

  1. Neural Functioning of Feeding Centers in Obese Youth
    ROBERT STANLEY SHERWIN; Fiscal Year: 2010
    ....
  2. PATHOPHYSIOLOGY OF TYPE 2 DIABETES IN YOUTH
    Sonia Caprio; Fiscal Year: 2005
    ..The study proposed here will not only provide further insights in the pathophysiology of T2DM in obese youth but will serve as a template for a large intervention study for the prevention of T2DM in this group. ..
  3. PATHOPHYSIOLOGY OF TYPE 2 DIABETES IN YOUTH
    Sonia Caprio; Fiscal Year: 2006
    ..The study proposed here will not only provide further insights in the pathophysiology of T2DM in obese youth but will serve as a template for a large intervention study for the prevention of T2DM in this group. ..
  4. Metabolic Markers and Predictors of Childhood Obesity
    Sonia Caprio; Fiscal Year: 2006
    ..abstract_text> ..
  5. Metabolic Markers and Predictors of Childhood Obesity
    Sonia Caprio; Fiscal Year: 2010
    ..The present studies will focus on determining what might cause fat to accumulate in the muscle and deep abdominal cavity. ..
  6. PATHOPHYSIOLOGY OF TYPE 2 DIABETES IN YOUTH
    Sonia Caprio; Fiscal Year: 2009
    ..The study proposed here will not only provide further insights in the pathophysiology of T2DM in obese youth but will serve as a template for a large intervention study for the prevention of T2DM in this group. ..
  7. Metabolic Markers and Predictors of Childhood Obesity
    Sonia Caprio; Fiscal Year: 2007
    ..abstract_text> ..
  8. Multi-Center Study of the Treatment of T2DM in Youth
    Sonia Caprio; Fiscal Year: 2007
    ..abstract_text> ..
  9. PATHOPHYSIOLOGY OF TYPE 2 DIABETES IN YOUTH
    Sonia Caprio; Fiscal Year: 2007
    ..The study proposed here will not only provide further insights in the pathophysiology of T2DM in obese youth but will serve as a template for a large intervention study for the prevention of T2DM in this group. ..
  10. PATHOPHYSIOLOGY OF METABOLIC DEFECTS OF JUVENILE OBESITY
    Sonia Caprio; Fiscal Year: 2007
    ....
  11. Metabolic Markers and Predictors of Childhood Obesity
    Sonia Caprio; Fiscal Year: 2009
    ..The present studies will focus on determining what might cause fat to accumulate in the muscle and deep abdominal cavity. ..
  12. Metabolic Markers and Predictors of Childhood Obesity
    Sonia Caprio; Fiscal Year: 2005
    ..abstract_text> ..
  13. PATHOPHYSIOLOGY OF TYPE 2 DIABETES IN YOUTH
    Sonia Caprio; Fiscal Year: 2004
    ..The long-term goal is to generate data that will lead to the development of new strategies for the prevention and treatment of type 2 diabetes in youth. ..
  14. METABOLIC PREDICTORS AND MARKERS OF CHILDHOOD OBESITY
    Sonia Caprio; Fiscal Year: 1999
    ..The long-term goal is to generate data that will lead to the development of new strategies for the prevention and treatment of juvenile obesity. ..
  15. METABOLIC PREDICTORS AND MARKERS OF CHILDHOOD OBESITY
    Sonia Caprio; Fiscal Year: 1991
    ..In summary, these studies will provide new important data on the mechanisms underlying the development of obesity in humans...
  16. METABOLIC PREDICTORS AND MARKERS OF CHILDHOOD OBESITY
    Sonia Caprio; Fiscal Year: 1992
    ..In summary, these studies will provide new important data on the mechanisms underlying the development of obesity in humans...
  17. METABOLIC PREDICTORS AND MARKERS OF CHILDHOOD OBESITY
    Sonia Caprio; Fiscal Year: 1993
    ..In summary, these studies will provide new important data on the mechanisms underlying the development of obesity in humans...
  18. METABOLIC PREDICTORS AND MARKERS OF CHILDHOOD OBESITY
    Sonia Caprio; Fiscal Year: 2000
    ..The long-term goal is to generate data that will lead to the development of new strategies for the prevention and treatment of juvenile obesity. ..
  19. PATHOPHYSIOLOGY OF TYPE 2 DIABETES IN YOUTH
    Sonia Caprio; Fiscal Year: 2000
    ..The long-term goal is to generate data that will lead to the development of new strategies for the prevention and treatment of type 2 diabetes in youth. ..
  20. PATHOPHYSIOLOGY OF TYPE 2 DIABETES IN YOUTH
    Sonia Caprio; Fiscal Year: 2001
    ..The long-term goal is to generate data that will lead to the development of new strategies for the prevention and treatment of type 2 diabetes in youth. ..
  21. A WEIGHT CONTROL MODEL FOR INNER CITY MINORITY CHILDREN
    Sonia Caprio; Fiscal Year: 2002
    ..The ultimate goal of this trial is to empower AA children and caregivers with the knowledge and skills necessary to promote fitness and wellness. ..
  22. PATHOPHYSIOLOGY OF TYPE 2 DIABETES IN YOUTH
    Sonia Caprio; Fiscal Year: 2002
    ..The long-term goal is to generate data that will lead to the development of new strategies for the prevention and treatment of type 2 diabetes in youth. ..
  23. Metabolic Markers and Predictors of Childhood Obesity
    Sonia Caprio; Fiscal Year: 2003
    ..abstract_text> ..
  24. PATHOPHYSIOLOGY OF TYPE 2 DIABETES IN YOUTH
    Sonia Caprio; Fiscal Year: 2003
    ..The long-term goal is to generate data that will lead to the development of new strategies for the prevention and treatment of type 2 diabetes in youth. ..
  25. Metabolic Markers and Predictors of Childhood Obesity
    Sonia Caprio; Fiscal Year: 2004
    ..abstract_text> ..
  26. Study to Investigate the Pathophysiology of Type 2 Diabetes in Youth
    Sonia Caprio; Fiscal Year: 2010
    ..Our long term goal is to generate information on both the genetics as well as the pathophysiology of Type 2 Diabetes in Youth, which ultimately might guide us towards better preventive and treatment avenues. ..