Margaret S Bynoe

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi request reprint Epicutaneous immunization with autoantigenic peptides induces T suppressor cells that prevent experimental allergic encephalomyelitis
    Margaret S Bynoe
    Section of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA
    Immunity 19:317-28. 2003
  2. pmc T cells from epicutaneously immunized mice are prone to T cell receptor revision
    Margaret S Bynoe
    Section of Immunobiology, Howard Hughes Medical Institute and Yale University School of Medicine, New Haven, CT 06520, USA
    Proc Natl Acad Sci U S A 102:2898-903. 2005
  3. ncbi request reprint Antigen-induced suppressor T cells from the skin point of view: suppressor T cells induced through epicutaneous immunization
    Margaret S Bynoe
    Section of Immunobiology, Yale University School of Medicine, and Howard Hughes Medical Institute, 300 Cedar St, New Haven, CT 06520 8011, USA
    J Neuroimmunol 167:4-12. 2005
  4. ncbi request reprint Semaphorin 7A is a negative regulator of T cell responses
    Agnieszka K Czopik
    Section of Immunobiology, Yale University, New Haven, Connecticut 06520, USA
    Immunity 24:591-600. 2006
  5. pmc Control of experimental autoimmune encephalomyelitis by CD4+ suppressor T cells: peripheral versus in situ immunoregulation
    Margaret S Bynoe
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York 14850, USA
    J Neuroimmunol 191:61-9. 2007
  6. doi request reprint Foxp3+CD4+ T cell-mediated immunosuppression involves extracellular nucleotide catabolism
    Margaret S Bynoe
    College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA
    Trends Immunol 29:99-102. 2008
  7. pmc CD73 is required for efficient entry of lymphocytes into the central nervous system during experimental autoimmune encephalomyelitis
    Jeffrey H Mills
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    Proc Natl Acad Sci U S A 105:9325-30. 2008

Collaborators

Detail Information

Publications7

  1. ncbi request reprint Epicutaneous immunization with autoantigenic peptides induces T suppressor cells that prevent experimental allergic encephalomyelitis
    Margaret S Bynoe
    Section of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA
    Immunity 19:317-28. 2003
    ..There was no CD4 T cell infiltration in the brain of protected mice. Finally, ECi with autoantigenic peptides protected two nontransgenic models from relapsing-remitting EAE in an antigen-specific and antigen dose-dependent manner...
  2. pmc T cells from epicutaneously immunized mice are prone to T cell receptor revision
    Margaret S Bynoe
    Section of Immunobiology, Howard Hughes Medical Institute and Yale University School of Medicine, New Haven, CT 06520, USA
    Proc Natl Acad Sci U S A 102:2898-903. 2005
    ..The emergence of these cells did not depend on the thymic compartment. We conclude that in mice epicutaneously immunized with an autoantigen, peripheral specific T cells are susceptible to multiple mechanisms of tolerance...
  3. ncbi request reprint Antigen-induced suppressor T cells from the skin point of view: suppressor T cells induced through epicutaneous immunization
    Margaret S Bynoe
    Section of Immunobiology, Yale University School of Medicine, and Howard Hughes Medical Institute, 300 Cedar St, New Haven, CT 06520 8011, USA
    J Neuroimmunol 167:4-12. 2005
    ..We discuss the skin environment as a privileged anatomical site for therapeutic intervention against pro-inflammatory auto-immune disorders using non-invasive approaches for antigen delivery...
  4. ncbi request reprint Semaphorin 7A is a negative regulator of T cell responses
    Agnieszka K Czopik
    Section of Immunobiology, Yale University, New Haven, Connecticut 06520, USA
    Immunity 24:591-600. 2006
    ..These results demonstrate an important role of Sema7A in limiting autoimmune responses and add to growing evidence of shared signaling pathways used by the immune and nervous systems...
  5. pmc Control of experimental autoimmune encephalomyelitis by CD4+ suppressor T cells: peripheral versus in situ immunoregulation
    Margaret S Bynoe
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York 14850, USA
    J Neuroimmunol 191:61-9. 2007
    ..Finally, we give an overview of genes recently discovered to be important in regulation of the immune system that may also prove to be key players in the modulation of EAE and MS...
  6. doi request reprint Foxp3+CD4+ T cell-mediated immunosuppression involves extracellular nucleotide catabolism
    Margaret S Bynoe
    College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA
    Trends Immunol 29:99-102. 2008
    ..Novel studies now establish that, through the generation of the immunosuppressive factor adenosine, the ectoenzymes CD39 and CD73 are important contributors to the regulatory activity of Foxp3(+)CD4(+) T cells...
  7. pmc CD73 is required for efficient entry of lymphocytes into the central nervous system during experimental autoimmune encephalomyelitis
    Jeffrey H Mills
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    Proc Natl Acad Sci U S A 105:9325-30. 2008
    ....