Michael Bracken

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi request reprint Epidemiology as a liberal art: from graduate school to middle school, an unfulfilled agenda
    Michael B Bracken
    Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Department of Chronic Disease Epidemiology, Yale University School of Public Health, New Haven, CT Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT Department of Neurology, Yale University School of Medicine, New Haven, CT Electronic address
    Ann Epidemiol 24:171-3. 2014
  2. pmc Genome-wide association study identifies a maternal copy-number deletion in PSG11 enriched among preeclampsia patients
    Linlu Zhao
    Center for Perinatal, Pediatric and Environmental Epidemiology, Yale School of Public Health, New Haven, CT 06520, USA
    BMC Pregnancy Childbirth 12:61. 2012
  3. pmc Whole-exome sequencing of a pedigree segregating asthma
    Andrew T Dewan
    Department of Chronic Disease Epidemiology, Yale School of Public Health, 60 College St, New Haven, CT 06520, USA
    BMC Med Genet 13:95. 2012
  4. doi request reprint New models for large prospective studies: is there a risk of throwing out the baby with the bathwater?
    Michael B Bracken
    Center for Perinatal, Pediatric and Environmental Epidemiology, Yale University School of Public Health, One Church Street, 6th Floor, New Haven, CT 06510, USA
    Am J Epidemiol 177:285-9. 2013
  5. doi request reprint Implementing provider-based sampling for the National Children's Study: opportunities and challenges
    Kathleen Belanger
    School of Public Health, Yale University Schools of Public Health and Medicine, New Haven, CT 06510, USA
    Paediatr Perinat Epidemiol 27:20-6. 2013
  6. pmc Association between XRCC1 polymorphism 399 G->A and glioma among Caucasians: a systematic review and meta-analysis
    Daniel I Jacobs
    Yale School of Public Health, New Haven, CT, USA
    BMC Med Genet 13:97. 2012
  7. ncbi request reprint Steroids for acute spinal cord injury
    Michael B Bracken
    Department of Epidemiology and Public Health, Yale University Medical School, Box 20834, 60College Street, New Haven, CT, 06520 8034, USA
    Cochrane Database Syst Rev 1:CD001046. 2012
  8. pmc Folic acid supplementation in early pregnancy and asthma in children aged 6 years
    Marit P Martinussen
    Yale Center for Perinatal, Pediatric, and Environmental Epidemiology, Yale School of Public Health, New Haven, CT 06510, USA
    Am J Obstet Gynecol 206:72.e1-7. 2012
  9. pmc Effects of endotoxin exposure on childhood asthma risk are modified by a genetic polymorphism in ACAA1
    Joanne E Sordillo
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    BMC Med Genet 12:158. 2011
  10. pmc Association of CD14 -260 (-159) C>T and asthma: a systematic review and meta-analysis
    Linlu Zhao
    Center for Perinatal, Pediatric and Environmental Epidemiology, Yale School of Public Health, New Haven, Connecticut, USA
    BMC Med Genet 12:93. 2011

Research Grants

Detail Information

Publications71

  1. ncbi request reprint Epidemiology as a liberal art: from graduate school to middle school, an unfulfilled agenda
    Michael B Bracken
    Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Department of Chronic Disease Epidemiology, Yale University School of Public Health, New Haven, CT Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT Department of Neurology, Yale University School of Medicine, New Haven, CT Electronic address
    Ann Epidemiol 24:171-3. 2014
    ....
  2. pmc Genome-wide association study identifies a maternal copy-number deletion in PSG11 enriched among preeclampsia patients
    Linlu Zhao
    Center for Perinatal, Pediatric and Environmental Epidemiology, Yale School of Public Health, New Haven, CT 06520, USA
    BMC Pregnancy Childbirth 12:61. 2012
    ..This genome-wide association study (GWAS) aims to identify maternal single nucleotide polymorphisms (SNPs) and copy-number variants (CNVs) involved in the etiology of PE...
  3. pmc Whole-exome sequencing of a pedigree segregating asthma
    Andrew T Dewan
    Department of Chronic Disease Epidemiology, Yale School of Public Health, 60 College St, New Haven, CT 06520, USA
    BMC Med Genet 13:95. 2012
    ..Some of this "missing heritability" may be accounted for by family-specific coding variants found to be segregating with asthma...
  4. doi request reprint New models for large prospective studies: is there a risk of throwing out the baby with the bathwater?
    Michael B Bracken
    Center for Perinatal, Pediatric and Environmental Epidemiology, Yale University School of Public Health, One Church Street, 6th Floor, New Haven, CT 06510, USA
    Am J Epidemiol 177:285-9. 2013
    ..It is premature to reject the strengths of large national cohort studies in favor of a new model for which evidence of efficiency is insufficient...
  5. doi request reprint Implementing provider-based sampling for the National Children's Study: opportunities and challenges
    Kathleen Belanger
    School of Public Health, Yale University Schools of Public Health and Medicine, New Haven, CT 06510, USA
    Paediatr Perinat Epidemiol 27:20-6. 2013
    ..The primary sampling unit was 105 study locations (typically a county). The secondary sampling unit was the geographic unit (segment), but this was subsequently perceived to be an inefficient strategy...
  6. pmc Association between XRCC1 polymorphism 399 G->A and glioma among Caucasians: a systematic review and meta-analysis
    Daniel I Jacobs
    Yale School of Public Health, New Haven, CT, USA
    BMC Med Genet 13:97. 2012
    ..The known risk for glioma from high dose ionizing radiation makes associations between this polymorphism and glioma of particular interest...
  7. ncbi request reprint Steroids for acute spinal cord injury
    Michael B Bracken
    Department of Epidemiology and Public Health, Yale University Medical School, Box 20834, 60College Street, New Haven, CT, 06520 8034, USA
    Cochrane Database Syst Rev 1:CD001046. 2012
    ..Steroid treatment in the early hours after the injury is aimed at reducing the extent of permanent paralysis during the rest of the patient's life...
  8. pmc Folic acid supplementation in early pregnancy and asthma in children aged 6 years
    Marit P Martinussen
    Yale Center for Perinatal, Pediatric, and Environmental Epidemiology, Yale School of Public Health, New Haven, CT 06510, USA
    Am J Obstet Gynecol 206:72.e1-7. 2012
    ..The objective of the study was to assess whether folic acid intake during the first trimester of pregnancy is related to asthma in the offspring by the age of 6 years...
  9. pmc Effects of endotoxin exposure on childhood asthma risk are modified by a genetic polymorphism in ACAA1
    Joanne E Sordillo
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    BMC Med Genet 12:158. 2011
    ..Polymorphisms in the endotoxin-mediated TLR4 pathway genes have been associated with asthma and atopy. We aimed to examine how genetic polymorphisms in innate immunity pathways interact with endotoxin to influence asthma risk in children...
  10. pmc Association of CD14 -260 (-159) C>T and asthma: a systematic review and meta-analysis
    Linlu Zhao
    Center for Perinatal, Pediatric and Environmental Epidemiology, Yale School of Public Health, New Haven, Connecticut, USA
    BMC Med Genet 12:93. 2011
    ..The aim of this study was to estimate the combined likelihood of developing asthma given the CD14 -260C>T genotype...
  11. pmc Respiratory symptoms among infants at risk for asthma: association with surfactant protein A haplotypes
    Melinda M Pettigrew
    Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, USA
    BMC Med Genet 8:15. 2007
    ....
  12. pmc Association of surfactant protein A polymorphisms with otitis media in infants at risk for asthma
    Melinda M Pettigrew
    Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, USA
    BMC Med Genet 7:68. 2006
    ....
  13. ncbi request reprint Cotinine and spontaneous abortion: might variations in metabolism play a role?
    Michael B Bracken
    Center for Perinatal, Pediatric and Environmental Epidemiology, Yale University, 1 Church Street, New Haven 06510, CT
    Epidemiology 17:492-4. 2006
  14. ncbi request reprint Genomic epidemiology of complex disease: the need for an electronic evidence-based approach to research synthesis
    Michael B Bracken
    Center for Perinatal, Pediatric, and Environmental Epidemiology, Yale University School of Medicine, New Haven, CT 06510, USA
    Am J Epidemiol 162:297-301. 2005
    ....
  15. ncbi request reprint CRASH (Corticosteroid Randomization after Significant Head Injury Trial): landmark and storm warning
    Michael B Bracken
    Department of Epidemiology, Yale University Medical School New Haven, Connecticut 06520 8034, USA
    Neurosurgery 57:1300-2; discussion 1300-2. 2005
  16. ncbi request reprint Genetic and perinatal risk factors for asthma onset and severity: a review and theoretical analysis
    Michael B Bracken
    Center for Perinatal, Pediatric and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, USA
    Epidemiol Rev 24:176-89. 2002
  17. ncbi request reprint Asthma symptoms, severity, and drug therapy: a prospective study of effects on 2205 pregnancies
    Michael B Bracken
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Obstet Gynecol 102:739-52. 2003
    ..To prospectively examine in pregnant women whether asthma or asthma therapy influenced preterm delivery, intrauterine grown restriction (IUGR), or birthweight...
  18. ncbi request reprint Methylprednisolone and acute spinal cord injury: an update of the randomized evidence
    M B Bracken
    Department of Epidemiology, Yale University School of Medicine, 60 College Street, New Haven, Connecticut 06520, USA
    Spine (Phila Pa 1976) 26:S47-54. 2001
    ..This evidence base is used to evaluate the current status of methylprednisolone (MPSS) in the early treatment of acute spinal cord injury...
  19. ncbi request reprint Heterogeneity in assessing self-reports of caffeine exposure: implications for studies of health effects
    Michael B Bracken
    Perinatal Epidemiology Unit, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520 8034, USA
    Epidemiology 13:165-71. 2002
    ..Coffee and its metabolite caffeine are widely studied for their health effects but with inconclusive results. Caffeine is particularly difficult to assess, and therefore we explore heterogeneity of caffeine exposure...
  20. ncbi request reprint Neurological and functional status 1 year after acute spinal cord injury: estimates of functional recovery in National Acute Spinal Cord Injury Study II from results modeled in National Acute Spinal Cord Injury Study III
    Michael B Bracken
    Department of Epidemiology, School of Medicine, and Graduate School, Yale University, New Haven, Connecticut 06520 8034, USA
    J Neurosurg 96:259-66. 2002
    ..The safety of the therapy has also been questioned...
  21. ncbi request reprint Association of maternal caffeine consumption with decrements in fetal growth
    Michael B Bracken
    Center for Perinatal, Pediatric and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, USA
    Am J Epidemiol 157:456-66. 2003
    ..3 g) cups of coffee)...
  22. ncbi request reprint Exposure to NO2 and nitrous acid and respiratory symptoms in the first year of life
    Robert T van Strien
    Yale School of Public Health, Center for Perinatal, Pediatric and Environmental Epidemiology, New Haven, Connecticut, USA
    Epidemiology 15:471-8. 2004
    ..We estimate the independent effects of exposure to nitrogen dioxide and nitrous acid on respiratory symptoms during the first year of life...
  23. pmc Effect of pregnancy on maternal asthma symptoms and medication use
    Kathleen Belanger
    Center for Perinatal Pediatric and Environmental Epidemiology, Yale University School of Public Health, New Haven, Connecticut 06510, USA
    Obstet Gynecol 115:559-67. 2010
    ..To examine whether factors related to the patient or her treatment influence asthma severity during pregnancy...
  24. ncbi request reprint Effect of pregnancy and stage of pregnancy on asthma severity: a systematic review
    Helen L Kwon
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06520 8034, USA
    Am J Obstet Gynecol 190:1201-10. 2004
    ..Large, well-conducted population-based studies that explore different aspects of asthma severity are needed to substantiate these preliminary results...
  25. pmc Symptoms and medication use in children with asthma and traffic-related sources of fine particle pollution
    Janneane F Gent
    Center for Perinatal, Pediatric and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06510, USA
    Environ Health Perspect 117:1168-74. 2009
    ..5))] is a potential factor in the exacerbation of asthma. National air quality particle standards consider total mass, not composition or sources, and may not protect against health impacts related to specific components...
  26. pmc Integrated exposure modeling: a model using GIS and GLM
    Theodore R Holford
    Division of Biostatistics, Department of Epidemiology and Public Health, Yale School of Medicine, New Haven, CT 06520, USA
    Stat Med 29:116-29. 2010
    ..In the second example, estimated levels of nitrogen dioxide (NO(2)) from the model, as well as a separate spatial model, were used to analyze traffic-related health effects in a study of 761 infants...
  27. pmc Prenatal caffeine assessment: fetal and maternal biomarkers or self-reported intake?
    Laura M Grosso
    Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Yale University School of Medicine, Department of Epidemiology and Public Health, One Church Street, New Haven, CT 06510, USA
    Ann Epidemiol 18:172-8. 2008
    ..We sought to examine associations among measures of caffeine exposure, including maternal urine, umbilical cord blood, and maternal self report...
  28. ncbi request reprint E-cadherin immunohistochemical expression as a prognostic factor in infiltrating ductal carcinoma of the breast: a systematic review and meta-analysis
    Bonnie E Gould Rothberg
    Section of Chronic Disease Epidemiology, Yale University School of Public Health, 60 College Street, PO Box 208034, New Haven, CT 06520 8034, USA
    Breast Cancer Res Treat 100:139-48. 2006
    ....
  29. pmc Low-level ozone exposure and respiratory symptoms in infants
    Elizabeth W Triche
    Yale Center for Perinatal, Pediatric, and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06520 8034, USA
    Environ Health Perspect 114:911-6. 2006
    ..Environmental Protection Agency (EPA) ozone standards may not protect sensitive individuals. In this study we examined respiratory effects of ozone in infants who may be vulnerable, particularly if they are children of asthmatic mothers...
  30. ncbi request reprint Caffeine metabolites in umbilical cord blood, cytochrome P-450 1A2 activity, and intrauterine growth restriction
    Laura M Grosso
    Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Yale University, New Haven, CT 06510, USA
    Am J Epidemiol 163:1035-41. 2006
    ..21, 95% confidence interval: 1.07, 1.37), suggesting that CYP1A2 activity, and not the absolute levels of paraxanthine, influences fetal growth. No associations were observed between caffeine or any metabolites and preterm delivery...
  31. ncbi request reprint Infant otitis media and the use of secondary heating sources
    Melinda M Pettigrew
    Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven Connecticut 06520 8034, USA
    Epidemiology 15:13-20. 2004
    ..This prospective study investigated the association of exposure to indoor secondary heating sources with otitis media and recurrent otitis media risk in infants...
  32. pmc Chocolate consumption in pregnancy and reduced likelihood of preeclampsia
    Elizabeth W Triche
    Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Yale University, New Haven, CT 06510, USA
    Epidemiology 19:459-64. 2008
    ..Preeclampsia is a major pregnancy complication with cardiovascular manifestations. Recent studies suggest that chocolate consumption may benefit cardiovascular health...
  33. pmc Association of pediatric asthma severity with exposure to common household dust allergens
    Janneane F Gent
    Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, One Church Street, 6th Floor, New Haven, CT 06510, USA
    Environ Res 109:768-74. 2009
    ..Reducing exposure to household dust inhalant allergens has been proposed as one strategy to reduce asthma...
  34. pmc Association of indoor nitrogen dioxide exposure with respiratory symptoms in children with asthma
    Kathleen Belanger
    Yale Center for Perinatal, Pediatric, and Environmental Epidemiology, New Haven, CT 06510, USA
    Am J Respir Crit Care Med 173:297-303. 2006
    ..Chronic exposure to indoor nitrogen dioxide (NO2) is a public health concern. Over half of U.S. households have a source of NO2, and experimental data suggest potential for adverse respiratory effects...
  35. ncbi request reprint Infant respiratory symptoms associated with indoor heating sources
    Elizabeth W Triche
    Center for Perinatal, Pediatric and Environmental Epidemology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Am J Respir Crit Care Med 166:1105-11. 2002
    ..Fireplace use was not associated with any of the respiratory symptoms. Use of some heating sources appears related to respiratory symptoms in infants...
  36. pmc Levels of household mold associated with respiratory symptoms in the first year of life in a cohort at risk for asthma
    Janneane F Gent
    Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06510, USA
    Environ Health Perspect 110:A781-6. 2002
    ..We conclude that infants in this high-risk group who are exposed to high levels of Penicillium are at significant risk for wheeze and persistent cough...
  37. ncbi request reprint Symptoms of wheeze and persistent cough in the first year of life: associations with indoor allergens, air contaminants, and maternal history of asthma
    Kathleen Belanger
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520 8034, USA
    Am J Epidemiol 158:195-202. 2003
    ..23, 95% CI: 1.01, 1.49). This appears to have been the first study to measure all of these home exposures (indoor allergens, nitrogen dioxide, fungi) and to prospectively measure the frequency of infant wheeze and persistent cough...
  38. ncbi request reprint Association of low-level ozone and fine particles with respiratory symptoms in children with asthma
    Janneane F Gent
    Center for Perinatal, Pediatric, and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Conn 06510, USA
    JAMA 290:1859-67. 2003
    ..Exposure to ozone and particulate matter of 2.5 microm or less (PM2.5) in air at levels above current US Environmental Protection Agency (EPA) standards is a risk factor for respiratory symptoms in children with asthma...
  39. pmc Dust mite, cockroach, cat, and dog allergen concentrations in homes of asthmatic children in the northeastern United States: impact of socioeconomic factors and population density
    Brian P Leaderer
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06520 8034, USA
    Environ Health Perspect 110:419-25. 2002
    ..Mite and cockroach allergens have distinct and opposite associations with socioeconomic factors and population density...
  40. ncbi request reprint Association of asthma diagnosis, severity, symptoms, and treatment with risk of preeclampsia
    Elizabeth W Triche
    Center for Perinatal, Pediatric, and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut, USA
    Obstet Gynecol 104:585-93. 2004
    ..This prospective study examines associations between aspects of asthma (diagnosis, severity, symptoms, and medication use) and risk of preeclampsia...
  41. ncbi request reprint Strategies for identifying pregnancies in the automated medical records of the General Practice Research Database
    Janet R Hardy
    Center for Perinatal, Pediatric and Environmental Epidemiology, Yale University School of Public Health, 1 Church Street, 6th Floor, New Haven, CT 06510, USA
    Pharmacoepidemiol Drug Saf 13:749-59. 2004
    ..To develop a method for identifying the beginning and ending records of pregnancies in the automated medical records of the General Practice Research Database (GPRD)...
  42. ncbi request reprint Work, leisure-time physical activity, and risk of preeclampsia and gestational hypertension
    Audrey F Saftlas
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City 52242, USA
    Am J Epidemiol 160:758-65. 2004
    ..Consistent with other studies, these data suggest that regular physical activity during pregnancy may reduce preeclampsia risk...
  43. ncbi request reprint Association of early-onset otitis media in infants and exposure to household mould
    Melinda M Pettigrew
    Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520 8034, USA
    Paediatr Perinat Epidemiol 18:441-7. 2004
    ..We also found associations between day-care outside of the home and birth during the summer or fall season with early otitis media. This study is suggestive of a relationship between otitis media and mould that warrants further study...
  44. ncbi request reprint Indoor heating sources and respiratory symptoms in nonsmoking women
    Elizabeth W Triche
    Department of Epidemiology and Public Health, Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Yale University School of Medicine, 60 College Street, New Haven, CT 06520 8034, USA
    Epidemiology 16:377-84. 2005
    ....
  45. ncbi request reprint Caffeine metabolism, genetics, and perinatal outcomes: a review of exposure assessment considerations during pregnancy
    Laura M Grosso
    Yale Center for Perinatal, Pediatric, and Environmental Epidemiology, Yale University School of Medicine, Department of Epidemiology and Public Health, New Haven, CT 06510, USA
    Ann Epidemiol 15:460-6. 2005
    ....
  46. ncbi request reprint Duration of intrapartum prophylaxis for neonatal group B streptococcal disease: a systematic review
    Jessica L Illuzzi
    Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Obstet Gynecol 108:1254-65. 2006
    ..To examine published evidence regarding duration of intrapartum antibiotic prophylaxis administered to pregnant women colonized with group B Streptococcus (GBS) to reduce infant colonization with GBS and to prevent early-onset GBS sepsis...
  47. pmc Geographic variation in one-year recurrent ischemic stroke rates for elderly Medicare beneficiaries in the USA
    Norrina B Allen
    Division of Chronic Disease Epidemiology, Yale University School of Medicine, New Haven, CT 06520 8034, USA
    Neuroepidemiology 34:123-9. 2010
    ..Accordingly, we evaluated geographic variations in 1-year recurrent ischemic stroke rates in the USA with adjustment for patient characteristics...
  48. ncbi request reprint The epidemiology of asthma during pregnancy: prevalence, diagnosis, and symptoms
    Helen L Kwon
    Department of Epidemiology, Mailman School of Public Health, Columbia University, 722 West 168th Street, 7th Floor, New York, NY 10032, USA
    Immunol Allergy Clin North Am 26:29-62. 2006
    ....
  49. pmc Tissue biomarkers for prognosis in cutaneous melanoma: a systematic review and meta-analysis
    Bonnie E Gould Rothberg
    Department of Pathology, Yale University School of Medicine, New Haven, CT 06520, USA
    J Natl Cancer Inst 101:452-74. 2009
    ....
  50. ncbi request reprint The evidence base for complementary and alternative medicine: methods of Evidence Mapping with application to CAM
    David L Katz
    Yale Prevention Research Center, Department of Epidemiology and Public Health, Yale University School of Medicine, USA
    Altern Ther Health Med 9:22-30. 2003
    ..There is widespread concern regarding the adequacy of evidence for specific practices under the rubric of "complementary and alternative medicine" (CAM)...
  51. ncbi request reprint Asthma prevalence among pregnant and childbearing-aged women in the United States: estimates from national health surveys
    Helen L Kwon
    From the Center for Perinatal, Pediatric, andn Environmental Epidemiology, Yale University School of Public Health, New Haven, CT 06520, USA
    Ann Epidemiol 13:317-24. 2003
    ..Asthma is a major complication of pregnancy, but there are currently no reliable national estimates for the United States of asthma prevalence in pregnancy or in the childbearing years...
  52. pmc Does chocolate intake during pregnancy reduce the risks of preeclampsia and gestational hypertension?
    Audrey F Saftlas
    Department of Epidemiology, University of Iowa College of Public Health, Iowa City, USA
    Ann Epidemiol 20:584-91. 2010
    ..We analyzed a prospective cohort study to determine whether regular chocolate intake during pregnancy is associated with reduced risks of preeclampsia and gestational hypertension (GH)...
  53. pmc Association between reduced copy-number at T-cell receptor gamma (TCRgamma) and childhood allergic asthma: A possible role for somatic mosaicism
    Kyle M Walsh
    Center for Perinatal Pediatric and Environmental Epidemiology, Yale School of Public Health, New Haven, CT 06510, USA
    Mutat Res 690:89-94. 2010
    ..Further work is needed to resolve whether reduced copy-number at TCRgamma predisposes individuals to asthma, or whether deletion of this gene is a somatic response to the disease...
  54. ncbi request reprint Effect of fetal sex on airway lability in pregnant women with asthma
    Helen L Kwon
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA
    Am J Epidemiol 163:217-21. 2006
    ..This difference persisted throughout pregnancy. Among pregnant asthmatic women, carrying a female fetus is associated with worse maternal asthma, as assessed by greater airway lability, than is carrying a male fetus...
  55. doi request reprint Prenatal or early-life exposure to antibiotics and risk of childhood asthma: a systematic review
    William Murk
    Center for Perinatal, Pediatric and Environmental Epidemiology, Yale University School of Public Health, New Haven, CT 06510 3210, USA
    Pediatrics 127:1125-38. 2011
    ..The increasing prevalence of childhood asthma has been associated with low microbial exposure as described by the hygiene hypothesis...
  56. pmc Prenatal exposure to acetaminophen and asthma in children
    Elizabeth M Kang
    Center for Perinatal Pediatric and Environmental Epidemiology, Yale School of Public Health, New Haven, Connecticut 06510, USA
    Obstet Gynecol 114:1295-306. 2009
    ..To estimate whether prenatal exposure to acetaminophen is associated with risk of diagnosed asthma and asthma symptoms in children...
  57. ncbi request reprint Renal impairment and outcomes in heart failure: systematic review and meta-analysis
    Grace L Smith
    Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Am Coll Cardiol 47:1987-96. 2006
    ..We estimated the prevalence of renal impairment in heart failure (HF) patients and the magnitude of associated mortality risk using a systematic review of published studies...
  58. ncbi request reprint Two genetic pathways for age-related macular degeneration
    Andrew Dewan
    Department of Epidemiology and Public Health, Yale University, 60 College Street, New Haven, CT 06520, USA
    Curr Opin Genet Dev 17:228-33. 2007
    ..Furthermore, these variants will enable clinicians and investigators to identify people at high risk for this condition, thereby establishing the preconditions for preventing the disease...
  59. doi request reprint Why are so many epidemiology associations inflated or wrong? Does poorly conducted animal research suggest implausible hypotheses?
    Michael B Bracken
    School of Public Health and Medicine, Yale University, New Haven, CT, USA
    Ann Epidemiol 19:220-4. 2009
    ....
  60. ncbi request reprint Regarding "An unexpected distribution of sodium concentration in serum specimens stored for more than 30 years"
    Laura Grosso
    Ann Epidemiol 14:77-8; author reply 79-80. 2004
  61. ncbi request reprint Polymorphisms in the 5' region of the CD14 gene are associated with eczema in young children
    Augusto A Litonjua
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    J Allergy Clin Immunol 115:1056-62. 2005
    ..Variants in the CD14 gene (CD14) are hypothesized to be associated with atopic disorders. However, most studies have only investigated one polymorphism in this gene...
  62. ncbi request reprint Methylprednisolone and spinal cord injury
    Michael B Bracken
    J Neurosurg 96:140-1; author reply 142. 2002
  63. pmc Complement factor H polymorphism in age-related macular degeneration
    Robert J Klein
    Laboratory of Statistical Genetics, Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Science 308:385-9. 2005
    ..This polymorphism is in a region of CFH that binds heparin and C-reactive protein. The CFH gene is located on chromosome 1 in a region repeatedly linked to AMD in family-based studies...
  64. ncbi request reprint Peak expiratory flow rate variability is not affected by home combustion sources in a group of nonsmoking women
    William S Beckett
    Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    Arch Environ Occup Health 61:176-82. 2006
    ..88; 95% CI = 1.59-5.21) and black or Hispanic ethnicity (OR = 2.02; 95% CI = 1.27-3.22), but was not associated with use of any supplementary home combustion sources among either asthmatic or nonasthmatic women...
  65. ncbi request reprint Safety of medications prescribed before and during early pregnancy in a cohort of 81,975 mothers from the UK General Practice Research Database
    Janet R Hardy
    Division of Preventive and Behavioral Medicine, University of Massachusetts School of Medicine, Worcester, MA 01655, USA
    Pharmacoepidemiol Drug Saf 15:555-64. 2006
    ..To demonstrate a linkage methodology for mother and baby automated medical records, and describe frequency, type, and pregnancy risk level of medications prescribed during pregnancy in a GPRD cohort, 1991-1999...
  66. ncbi request reprint Timing of initial surfactant treatment for infants 23 to 29 weeks' gestation: is routine practice evidence based?
    Jeffrey D Horbar
    Department of Pediatrics, University of Vermont College of Medicine, Burlington, Vermont, USA
    Pediatrics 113:1593-602. 2004
    ..To describe the timing of initial surfactant treatment for high-risk preterm infants in routine practice and compare these findings with evidence from randomized trials and published guidelines...
  67. ncbi request reprint Asthma during pregnancy
    Michael B Bracken
    Obstet Gynecol 103:1001-2; author reply 1002. 2004
  68. pmc Prediction of residential pet and cockroach allergen levels using questionnaire information
    Ulrike Gehring
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Environ Health Perspect 112:834-9. 2004
    ..Knowledge of past pet ownership can improve pet allergen exposure assessment by means of questionnaire. However, for epidemiologic purposes, measured concentrations of allergens are necessary...
  69. ncbi request reprint Cochrane neonatal systematic reviews: a survey of the evidence for neonatal therapies
    John C Sinclair
    Department of Pediatrics, McMaster University Medical Centre, Room 3N11F, 1200 Main Street West, Hamilton, Ontario L8N 3Z5, Canada
    Clin Perinatol 30:285-304. 2003
    ..Most CNRG reviews were current. There is a continuing need to prepare systematic review of therapies not yet covered and to keep an increasing number of reviews up-to-date...
  70. ncbi request reprint Rosiglitazone and cardiovascular risk
    Michael B Bracken
    N Engl J Med 357:937-8; author reply 939-40. 2007
  71. pmc Collaborative quality improvement to promote evidence based surfactant for preterm infants: a cluster randomised trial
    Jeffrey D Horbar
    Vermont Oxford Network, 33 Kilburn Street, Burlington, VT 05401, USA
    BMJ 329:1004. 2004
    ..To test a multifaceted collaborative quality improvement intervention designed to promote evidence based surfactant treatment for preterm infants of 23-29 weeks' gestation...

Research Grants22

  1. Perinatal Risk of Asthma in Infants of Asthmatic Mothers
    Michael Bracken; Fiscal Year: 2007
    ..Identification of pregnancy and neonatal risk factors for infant asthma may offer opportunities for early prevention. ..
  2. EFFECTS OF CAFFEINE AND COFFEE ON FETAL DEVELOPMENT
    Michael Bracken; Fiscal Year: 1999
    ..75 to 2.0 (a=0.05, B=0.10). Preterm delivery and intra-uterine growth retardation are major health problems in their own right but also among the strongest predictors of infant mortality and long-term disability. ..
  3. ENVIRONMENTAL TOBACCO SMOKE AND PREGNANCY OUTCOME
    Michael Bracken; Fiscal Year: 1991
  4. EFFECTS OF ASTHMA SEVERITY AND MEDICATION IN PREGNANCY
    Michael Bracken; Fiscal Year: 2000
    ..In particular, any differences in the natural history, risks, and management of gestational asthma among white, black and Hispanic will be described. ..
  5. Perinatal Risk of Asthma in Infants of Asthmatic Mothers
    Michael Bracken; Fiscal Year: 2003
    ..Identification of pregnancy and neonatal risk factors for infant asthma may offer opportunities for early prevention. ..
  6. Paraxanthine and Reproductive Effects of Caffeine
    Michael Bracken; Fiscal Year: 2004
    ..abstract_text> ..
  7. Perinatal Risk of Asthma in Infants of Asthmatic Mothers
    Michael Bracken; Fiscal Year: 2004
    ..Identification of pregnancy and neonatal risk factors for infant asthma may offer opportunities for early prevention. ..
  8. Perinatal Risk of Asthma in Infants of Asthmatic Mothers
    Michael Bracken; Fiscal Year: 2005
    ..Identification of pregnancy and neonatal risk factors for infant asthma may offer opportunities for early prevention. ..
  9. ENVIRONMENTAL TOBACCO SMOKE AND PREGNANCY OUTCOME
    Michael Bracken; Fiscal Year: 1990
  10. EFFECTS OF ASTHMA SEVERITY AND MEDICATION IN PREGNANCY
    Michael Bracken; Fiscal Year: 1999
    ..In particular, any differences in the natural history, risks, and management of gestational asthma among white, black and Hispanic will be described. ..
  11. Paraxanthine and Reproductive Effects of Caffeine
    Michael Bracken; Fiscal Year: 2003
    ..abstract_text> ..
  12. Perinatal Risk of Asthma in Infants of Asthmatic Mothers
    Michael Bracken; Fiscal Year: 2006
    ..Identification of pregnancy and neonatal risk factors for infant asthma may offer opportunities for early prevention. ..