Kelly A Bordner

Summary

Affiliation: Yale University
Country: USA

Publications

  1. pmc Parallel declines in cognition, motivation, and locomotion in aging mice: association with immune gene upregulation in the medial prefrontal cortex
    Kelly A Bordner
    Yale University School of Medicine, Department of Psychiatry, New Haven, CT 06511, USA
    Exp Gerontol 46:643-59. 2011
  2. pmc Maternal separation with early weaning: a rodent model providing novel insights into neglect associated developmental deficits
    Becky C Carlyle
    Yale University School of Medicine, CT, USA
    Dev Psychopathol 24:1401-16. 2012
  3. pmc Neuroanatomical changes in a mouse model of early life neglect
    Alvaro Duque
    Department of Neurobiology, Yale University School of Medicine, New Haven, CT 06511 6624, USA
    Brain Struct Funct 217:459-72. 2012
  4. pmc cAMP-PKA phosphorylation of tau confers risk for degeneration in aging association cortex
    Becky C Carlyle
    Departments of Psychiatry and Neurobiology, Yale University School of Medicine, New Haven, CT 06511
    Proc Natl Acad Sci U S A 111:5036-41. 2014
  5. pmc Functional genomic and proteomic analysis reveals disruption of myelin-related genes and translation in a mouse model of early life neglect
    Kelly A Bordner
    Department of Psychiatry, Yale University School of Medicine New Haven, CT, USA
    Front Psychiatry 2:18. 2011
  6. pmc Maternal separation with early weaning: a novel mouse model of early life neglect
    Elizabeth D George
    Yale University School of Medicine, Department of Psychiatry, New Haven, CT 06511, USA
    BMC Neurosci 11:123. 2010
  7. pmc Cognitive dysfunction with aging and the role of inflammation
    Arthur A Simen
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
    Ther Adv Chronic Dis 2:175-95. 2011

Collaborators

Detail Information

Publications7

  1. pmc Parallel declines in cognition, motivation, and locomotion in aging mice: association with immune gene upregulation in the medial prefrontal cortex
    Kelly A Bordner
    Yale University School of Medicine, Department of Psychiatry, New Haven, CT 06511, USA
    Exp Gerontol 46:643-59. 2011
    ..These data suggest that, as in humans, cognition, motivation, and motoric performance in the mouse change together with age and are strongly associated with CNS immune gene upregulation...
  2. pmc Maternal separation with early weaning: a rodent model providing novel insights into neglect associated developmental deficits
    Becky C Carlyle
    Yale University School of Medicine, CT, USA
    Dev Psychopathol 24:1401-16. 2012
    ..Finally, we summarize the molecular characterization of these animals, including RNA profiling and label-free proteomics, which highlight protein translation and myelination as novel pathways of interest...
  3. pmc Neuroanatomical changes in a mouse model of early life neglect
    Alvaro Duque
    Department of Neurobiology, Yale University School of Medicine, New Haven, CT 06511 6624, USA
    Brain Struct Funct 217:459-72. 2012
    ..Moreover, our current knowledge of the mouse genome makes this model particularly suited for targeted anatomical, molecular, and pharmacological experimentation not yet possible in other species...
  4. pmc cAMP-PKA phosphorylation of tau confers risk for degeneration in aging association cortex
    Becky C Carlyle
    Departments of Psychiatry and Neurobiology, Yale University School of Medicine, New Haven, CT 06511
    Proc Natl Acad Sci U S A 111:5036-41. 2014
    ..Thus, the cAMP-Ca(2+) signaling mechanisms, needed for flexibly modulating network strength in young association cortex, confer vulnerability to degeneration when dysregulated with advancing age. ..
  5. pmc Functional genomic and proteomic analysis reveals disruption of myelin-related genes and translation in a mouse model of early life neglect
    Kelly A Bordner
    Department of Psychiatry, Yale University School of Medicine New Haven, CT, USA
    Front Psychiatry 2:18. 2011
    ..These findings are likely to prove useful in understanding the mechanism by which early life neglect affects brain structure, cognition, and behavior...
  6. pmc Maternal separation with early weaning: a novel mouse model of early life neglect
    Elizabeth D George
    Yale University School of Medicine, Department of Psychiatry, New Haven, CT 06511, USA
    BMC Neurosci 11:123. 2010
    ..Maternal separation is a commonly used model of early life neglect, but has led to inconsistent results in the mouse...
  7. pmc Cognitive dysfunction with aging and the role of inflammation
    Arthur A Simen
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
    Ther Adv Chronic Dis 2:175-95. 2011
    ..New insights from preclinical and clinical research may give rise to novel therapeutics which may have efficacy in slowing or preventing cognitive decline with advancing age...