Affiliation: Yale University
- Predictors for the healing of transmetatarsal amputations: retrospective study of 91 amputationsPeter Blume
Department of Vascular Surgery, Yale University School of Medicine, New Haven, CT 06515, USA
Vascular 15:126-33. 2007..0001). In group 1, 20 of 27 (74%) limbs that were revascularized healed (p = .0336). Nonhealing amputations were associated with end-stage renal disease (13 of 19; 68%) (p = .0209) and leukocytosis (13 of 19; 68%) (p = .0052)...
- Charcot neuroarthropathy of the foot and ankle: diagnosis and management strategiesPeter A Blume
Orthopedics and Rehabilitation, and Anesthesia, Yale School of Medicine, 20 York Street, New Haven, CT 06510, USA Electronic address
Clin Podiatr Med Surg 31:151-72. 2014..The treatment of Charcot osteoarthropathy with concurrent osteomyelitis is also discussed. ..
- The role of plastic surgery for soft tissue coverage of the diabetic foot and anklePeter A Blume
Orthopedics and Rehabilitation, and Anesthesia, Yale School of Medicine, 800 Howard Street, New Haven, CT 06519, USA Electronic address
Clin Podiatr Med Surg 31:127-50. 2014..Wound evaluation coupled with the knowledge of various closure techniques and their indications will arm the surgeon with the tools for a successful closure. ..
- Case report and review of primary bone diffuse large B-cell lymphoma involving the calcaneusPeter Blume
Section of Podiatric Surgery, Department of Orthopedics, Yale University School of Medicine, New Haven, CT 06511, USA
J Foot Ankle Surg 52:666-72. 2013..To our knowledge, this is the first case report of primary bone, diffuse, large B-cell lymphoma of the calcaneus to be treated with a combination of surgical excision, chemotherapy, and radiotherapy. ..
- Comparison of negative pressure wound therapy using vacuum-assisted closure with advanced moist wound therapy in the treatment of diabetic foot ulcers: a multicenter randomized controlled trialPeter A Blume
North American Center for Limb Preservation, 506 Blake St, New Haven, CT 06515, USA
Diabetes Care 31:631-6. 2008..The purpose of this study was to evaluate safety and clinical efficacy of negative pressure wound therapy (NPWT) compared with advanced moist wound therapy (AMWT) to treat foot ulcers in diabetic patients...
- Retrospective evaluation of clinical outcomes in subjects with split-thickness skin graft: comparing V.A.C.® therapy and conventional therapy in foot and ankle reconstructive surgeriesPeter A Blume
Anesthesia and Orthopedics and Rehabilitation, Yale School of Medicine, 333 Cedar Street, TMP 3, PO Box 208051, New Haven, CT 06520 8051, USA
Int Wound J 7:480-7. 2010..NPWT/ROCF is an excellent alternative for securing an STSG and is associated with improved graft survival as measured by a reduction in the number of repeated STSGs and graft failure complications...
- The effect of different frequencies of stretch on human dermal keratinocyte proliferation and survivalKengo Nishimura
Department of Surgery, Yale University School of Medicine, New Haven, Connecticut 06520 8062, USA
J Surg Res 155:125-31. 2009..After experiencing I stretch for 2 d, keratinocyte proliferation rates were significantly decreased. This decrease was most likely not due to apoptosis as TUNEL-positive cells only increased for cells treated with an AKT inhibitor...
- Formulated collagen gel accelerates healing rate immediately after application in patients with diabetic neuropathic foot ulcersPeter Blume
Affiliated Foot Surgeons, New Haven, Connecticut, USA
Wound Repair Regen 19:302-8. 2011..Both GAM501 and FCG appeared to be safe and well tolerated, and alternate dosing schedules hold promise to improve overall complete wound closure in adequately powered trials...
- Safety of local anesthesia combined with monitored intravenous sedation for American Society of Anesthesiologists 3 and 4 patients undergoing lower limb-preservation proceduresNalini Vadivelu
Department of Anesthesiology, Yale University, New Haven, CT, USA
J Foot Ankle Surg 49:152-4. 2010..We suggest that the performance of peripheral foot and ankle blocks with monitored intravenous sedation appears to be a safe and useful option for ASA 3 and 4 patients undergoing limb-preservation surgery...
- New modalities in the chronic ischemic diabetic foot managementSherif Y Shalaby
Department of Vascular Surgery, Yale University School of Medicine, 310 Cedar Street, New Haven, CT 06510, USA
Clin Podiatr Med Surg 31:27-42. 2014..This article discusses newer modalities that have been proposed to improve CIDF efficiently, safely, and effectively either alone or as adjuvants to conventional therapy. ..
- Effect of different frequencies of tensile strain on human dermal fibroblast proliferation and survivalKengo Nishimura
Department of Surgery, Yale University School of Medicine, New Haven, CT 06520 8062, USA
Wound Repair Regen 15:646-56. 2007..The inhibitors of p38 MAPK and MAPK/ERK kinase as well as dominant-negative AKT reduced cell number after both HF and I stretch but these pathways were not critical for the stretch-induced decrease in cell number...
- Angiosomes of the foot and ankle and clinical implications for limb salvage: reconstruction, incisions, and revascularizationChristopher E Attinger
Limb Center, Georgetown University Medical Center, Washington, DC 20007, USA
Plast Reconstr Surg 117:261S-293S. 2006..Understanding the angiosomes of the foot and ankle and the interaction among their source arteries is clinically useful in surgery of the foot and ankle, especially in the presence of peripheral vascular disease...
- Soft tissue reconstruction of the diabetic footGary Peter Jolly
New Britain General Hospital, 100 Grand Street, New Britain, CT 06050, USA
Clin Podiatr Med Surg 20:757-81. 2003..When developing a team to treat chronic diabetic wounds, a reconstructive foot and ankle surgeon trained in these techniques is an appropriate addition to the team...
- Diabetic foot infections and antibiotic therapyThomas Zgonis
The Center for Reconstructive Foot Surgery, 440 New Britain Avenue, Plainville, CT 06062, USA
Clin Podiatr Med Surg 20:655-69. 2003..Aggressive surgical debridement and appropriate and adequate antibiotic therapy are necessary to successfully treat severe foot infections and permit faster recovery...