Hilary Blumberg

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi request reprint Preliminary evidence for medication effects on functional abnormalities in the amygdala and anterior cingulate in bipolar disorder
    Hilary P Blumberg
    Mood Disorders Research Program, Department of Psychiatry, Yale University School of Medicine, 300 George Street, Suite 901, New Haven, CT 06511, USA
    Psychopharmacology (Berl) 183:308-13. 2005
  2. pmc Olfactocentric paralimbic cortex morphology in adolescents with bipolar disorder
    Fei Wang
    Department of Psychiatry, Yale School of Medicine, New Haven, CT 06511, USA
    Brain 134:2005-12. 2011
  3. pmc Corticolimbic functional connectivity in adolescents with bipolar disorder
    Fei Wang
    Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, United States of America
    PLoS ONE 7:e50177. 2012
  4. ncbi request reprint Dimensions in the development of bipolar disorder
    Hilary P Blumberg
    Mood Disorders Research Program, Department of Psychiatry, Yale School of Medicine, REAP Depression Center, West Haven VA CT Healthcare System, New Haven, CT 06511, USA
    Biol Psychiatry 62:104-6. 2007
  5. ncbi request reprint Age, rapid-cycling, and pharmacotherapy effects on ventral prefrontal cortex in bipolar disorder: a cross-sectional study
    Hilary P Blumberg
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06511, USA
    Biol Psychiatry 59:611-8. 2006
  6. pmc Preliminary evidence for persistent abnormalities in amygdala volumes in adolescents and young adults with bipolar disorder
    Hilary P Blumberg
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06511, USA
    Bipolar Disord 7:570-6. 2005
  7. ncbi request reprint Significance of adolescent neurodevelopment for the neural circuitry of bipolar disorder
    Hilary P Blumberg
    Department of Psychiatry, Yale University School of Medicine, VA Depression Research Center REAP, VA Connecticut Healthcare System 116 A, 950 Campbell Avenue, West Haven, CT 06516, USA
    Ann N Y Acad Sci 1021:376-83. 2004
  8. ncbi request reprint Amygdala and hippocampal volumes in adolescents and adults with bipolar disorder
    Hilary P Blumberg
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
    Arch Gen Psychiatry 60:1201-8. 2003
  9. ncbi request reprint Frontostriatal abnormalities in adolescents with bipolar disorder: preliminary observations from functional MRI
    Hilary P Blumberg
    Department of Psychiatry and Diagnostic Radiology and the Yale Child Study Center, Yale University School of Medicine, New Haven, Conn, 06516, USA
    Am J Psychiatry 160:1345-7. 2003
  10. ncbi request reprint A functional magnetic resonance imaging study of bipolar disorder: state- and trait-related dysfunction in ventral prefrontal cortices
    Hilary P Blumberg
    Department of Psychiatry, Yale University School of Medicine, New Haven, Conn, USA
    Arch Gen Psychiatry 60:601-9. 2003

Research Grants

Collaborators

Detail Information

Publications20

  1. ncbi request reprint Preliminary evidence for medication effects on functional abnormalities in the amygdala and anterior cingulate in bipolar disorder
    Hilary P Blumberg
    Mood Disorders Research Program, Department of Psychiatry, Yale University School of Medicine, 300 George Street, Suite 901, New Haven, CT 06511, USA
    Psychopharmacology (Berl) 183:308-13. 2005
    ..Abnormal amygdala and frontocortical responses to emotional stimuli are implicated in bipolar disorder (BD) and have been proposed as potential treatment targets...
  2. pmc Olfactocentric paralimbic cortex morphology in adolescents with bipolar disorder
    Fei Wang
    Department of Psychiatry, Yale School of Medicine, New Haven, CT 06511, USA
    Brain 134:2005-12. 2011
    ....
  3. pmc Corticolimbic functional connectivity in adolescents with bipolar disorder
    Fei Wang
    Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, United States of America
    PLoS ONE 7:e50177. 2012
    ..This suggests that amygdala-anterior paralimbic connectivity abnormalities are early features of BD that emerge at least by adolescence in the disorder...
  4. ncbi request reprint Dimensions in the development of bipolar disorder
    Hilary P Blumberg
    Mood Disorders Research Program, Department of Psychiatry, Yale School of Medicine, REAP Depression Center, West Haven VA CT Healthcare System, New Haven, CT 06511, USA
    Biol Psychiatry 62:104-6. 2007
  5. ncbi request reprint Age, rapid-cycling, and pharmacotherapy effects on ventral prefrontal cortex in bipolar disorder: a cross-sectional study
    Hilary P Blumberg
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06511, USA
    Biol Psychiatry 59:611-8. 2006
    ..However, the developmental trajectory of VPFC morphological abnormalities in BD is unknown. This study investigated potential age-dependent volume abnormalities in VPFC in BD...
  6. pmc Preliminary evidence for persistent abnormalities in amygdala volumes in adolescents and young adults with bipolar disorder
    Hilary P Blumberg
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06511, USA
    Bipolar Disord 7:570-6. 2005
    ..Here we use a within-subject longitudinal design to investigate whether amygdala volume abnormalities persist in adolescents and young adults with BD over a time interval of approximately 2 years...
  7. ncbi request reprint Significance of adolescent neurodevelopment for the neural circuitry of bipolar disorder
    Hilary P Blumberg
    Department of Psychiatry, Yale University School of Medicine, VA Depression Research Center REAP, VA Connecticut Healthcare System 116 A, 950 Campbell Avenue, West Haven, CT 06516, USA
    Ann N Y Acad Sci 1021:376-83. 2004
    ..This potential neurodevelopmental model for BD could have important implications for the recognition of early signs of the disorder and for age-specific treatment strategies...
  8. ncbi request reprint Amygdala and hippocampal volumes in adolescents and adults with bipolar disorder
    Hilary P Blumberg
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
    Arch Gen Psychiatry 60:1201-8. 2003
    ..Appreciation of whether volumetric abnormalities are early features of BD or whether the abnormalities represent neurodegenerative changes associated with illness duration is limited by the paucity of data in juvenile samples...
  9. ncbi request reprint Frontostriatal abnormalities in adolescents with bipolar disorder: preliminary observations from functional MRI
    Hilary P Blumberg
    Department of Psychiatry and Diagnostic Radiology and the Yale Child Study Center, Yale University School of Medicine, New Haven, Conn, 06516, USA
    Am J Psychiatry 160:1345-7. 2003
    ..This study investigated whether the functional abnormalities in prefrontal systems observed in adult bipolar disorder are manifested in adolescents with this illness...
  10. ncbi request reprint A functional magnetic resonance imaging study of bipolar disorder: state- and trait-related dysfunction in ventral prefrontal cortices
    Hilary P Blumberg
    Department of Psychiatry, Yale University School of Medicine, New Haven, Conn, USA
    Arch Gen Psychiatry 60:601-9. 2003
    ..We sought to characterize state- and trait-related functional impairment in frontal systems in bipolar disorder...
  11. pmc Increased peripheral blood expression of electron transport chain genes in bipolar depression
    Robert D Beech
    Department of Psychiatry, Yale University School of Medicine, 300 George Street, New Haven, CT 06511, USA
    Bipolar Disord 12:813-24. 2010
    ..To identify specific genetic pathways showing altered expression in peripheral blood of depressed subjects with bipolar disorder (BPD)...
  12. ncbi request reprint Amygdala hyperreactivity in borderline personality disorder: implications for emotional dysregulation
    Nelson H Donegan
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06520 8098, USA
    Biol Psychiatry 54:1284-93. 2003
    ..We hypothesized that amygdala hyperreactivity contributes to hypervigilance, emotional dysregulation, and disturbed interpersonal relations in BPD...
  13. pmc Abnormal anterior cingulum integrity in bipolar disorder determined through diffusion tensor imaging
    Fei Wang
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06511, USA
    Br J Psychiatry 193:126-9. 2008
    ..The cingulum is an important candidate structure for study in bipolar disorder as it provides substantial white matter connections within the corticolimbic neural system that subserves emotional regulation involved in the disorder...
  14. doi request reprint The next wave in neuroimaging research in pediatric bipolar disorder
    Hilary P Blumberg
    J Am Acad Child Adolesc Psychiatry 47:483-5. 2008
  15. ncbi request reprint Reduced ventral anterior cingulate and amygdala volumes in medication-naïve females with major depressive disorder: A voxel-based morphometric magnetic resonance imaging study
    Yanqing Tang
    Department of Psychiatry, The Second Xiangya Hospital, Central South University, 86, Mid Renmin Road, Changsha, Hunan 410011, PR China
    Psychiatry Res 156:83-6. 2007
    ..These results suggest that volume reductions in vACC and amygdala in females with MDD are present at illness onset...
  16. ncbi request reprint Frontotemporal neural systems in bipolar disorder
    Hilary P Blumberg
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Semin Clin Neuropsychiatry 7:243-54. 2002
    ..We suggest that ventral and medial prefrontal and amygdalar abnormalities may play important roles in a subset of BD symptoms and are potential targets for treatments...
  17. ncbi request reprint The interaction of emotional and cognitive neural systems in emotionally guided response inhibition
    Keith M Shafritz
    Psychology Department, Drew University, Madison, NJ 07940, USA
    Neuroimage 31:468-75. 2006
    ..These findings suggest that inhibition within an emotional context recruits a distinct set of brain regions that includes areas beyond those normally activated by response inhibition tasks and that can be modulated by emotional valence...
  18. ncbi request reprint An FMRI Stroop task study of ventromedial prefrontal cortical function in pathological gamblers
    Marc N Potenza
    Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, Room S 104, 34 Park Street, New Haven, CT 06519, USA
    Am J Psychiatry 160:1990-4. 2003
    ..The authors used the Stroop paradigm to test attention and response inhibition during the presentation of congruent and incongruent stimuli in male pathological gamblers and a group of comparison subjects...
  19. ncbi request reprint CHRM2 gene predisposes to alcohol dependence, drug dependence and affective disorders: results from an extended case-control structured association study
    Xingguang Luo
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Hum Mol Genet 14:2421-34. 2005
    ..In addition, a specific diplotype might inversely affect risk for AD and DD and risk for affective disorders...
  20. ncbi request reprint The neuroanatomy of mood disorders. Introduction
    Hilary P Blumberg
    Semin Clin Neuropsychiatry 7:221-2. 2002

Research Grants12

  1. Genetics of Hippocampal Deficits in Bipolar Disorder
    Hilary Blumberg; Fiscal Year: 2009
    ..To the best of our knowledge this is the first integrated neuroimaging and genetic study of modification of regional brain abnormalities in BD by genetic variations. ..
  2. Development of Brain Abnormalities in Bipolar Disorder
    Hilary Blumberg; Fiscal Year: 2007
    ..abstract_text> ..
  3. Genetic Influences on Frontotemporal Connectivity in Bipolar Disorder
    Hilary P Blumberg; Fiscal Year: 2011
    ....