Research Topics
Species | Matthew J BizzarroSummaryAffiliation: Yale University Country: USA Publications
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Detail Information
Publications
Necrotizing enterocolitis in newborns: pathogenesis, prevention and managementAlecia M Thompson
Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520 8064, USA
Drugs 68:1227-38. 2008..Recent promising data indicate that prophylactic use of probiotics may play a role in preventing the onset of NEC. However, more large-scale, definitive studies are needed...
Health care-associated infections in the neonatal intensive care unit: barriers to continued successMatthew J Bizzarro
Division of Perinatal Medicine, Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520 8064, USA
Semin Perinatol 36:437-44. 2012..Therefore, more concerted efforts are needed in these areas for continued progress to occur...- Circulating stem cells in extremely preterm neonatesMatthew J Bizzarro
Department of Pediatrics, Division of Perinatal Medicine, Yale University School of Medicine, New Haven, CT 06520 8064, USA
Acta Paediatr 96:521-5. 2007..To measure circulating CD34+ cell levels in premature neonates and to correlate the initial CD34+ counts with measures of pulmonary function and neonatal morbidity... - A quality improvement initiative to reduce central line-associated bloodstream infections in a neonatal intensive care unitMatthew J Bizzarro
Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520 8064, USA
Infect Control Hosp Epidemiol 31:241-8. 2010..To reduce the rate of late-onset sepsis in a neonatal intensive care unit (NICU) by decreasing the rate of central line-associated bloodstream infection (CLABSI)... - Infections acquired during extracorporeal membrane oxygenation in neonates, children, and adultsMatthew J Bizzarro
Yale University School of Medicine, New Haven, CT, USA
Pediatr Crit Care Med 12:277-81. 2011..To determine current rates, risk factors, and causal organisms related to infections acquired during extracorporeal membrane oxygenation (ECMO)... 
The impact of environmental and genetic factors on neonatal late-onset sepsisMatthew J Bizzarro
Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520 8064, USA
J Pediatr 158:234-8.e1. 2011..To assess the genetic contribution to late-onset sepsis in twins in the newborn intensive care unit...- The genetic susceptibility to respiratory distress syndromeOrly Levit
Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520, USA
Pediatr Res 66:693-7. 2009..We found 49.7% (p = 0.04) of the variance in liability to RDS was the result of genetic factors alone. We conclude that there is a significant genetic susceptibility to RDS in preterm infants... - Matched case-control analysis of polymicrobial bloodstream infection in a neonatal intensive care unitMatthew J Bizzarro
Division of Perinatal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520 8064, USA
Infect Control Hosp Epidemiol 29:914-20. 2008..To compare and contrast the epidemiology of polymicrobial and monomicrobial bloodstream infections (BSIs) in newborn intensive care unit (NICU) patients... - Changing patterns in neonatal Escherichia coli sepsis and ampicillin resistance in the era of intrapartum antibiotic prophylaxisMatthew J Bizzarro
Division of Perinatal Medicine, Department of Pediatrics, Yale University School of Medicine, 333 Cedar St, New Haven, CT 06520 8064, USA
Pediatrics 121:689-96. 2008..The goal was to determine current trends in Escherichia coli-related early- and late-onset sepsis and patterns of ampicillin resistance in relation to institutional changes in the use of intrapartum antibiotic prophylaxis... - Case-control analysis of endemic Serratia marcescens bacteremia in a neonatal intensive care unitMatthew J Bizzarro
Divisions of Perinatal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520 8064, USA
Arch Dis Child Fetal Neonatal Ed 92:F120-6. 2007..Serratia marcescens is an opportunistic gram-negative rod which typically infects compromised hosts... - COL4A1 mutation in preterm intraventricular hemorrhageKaya Bilguvar
Department of Neurosurgery, Yale University School of Medicine, New Haven, CT 06520, USA
J Pediatr 155:743-5. 2009..We report a rare variant in COL4A1 associated with intraventricular hemorrhage in dizygotic preterm twins. These results expand the spectrum of diseases attributable to mutations in type IV procollagens... - Early onset neonatal sepsis: the burden of group B Streptococcal and E. coli disease continuesBarbara J Stoll
Department of Pediatrics, Emory University School of Medicine, and Children s Healthcare of Atlanta, 2015 Uppergate Drive, Atlanta, GA, USA
Pediatrics 127:817-26. 2011..Guidelines for prevention of group B streptococcal (GBS) infection have successfully reduced early onset (EO) GBS disease. Study results suggest that Escherichia coli is an important EO pathogen... - Genetic contribution to patent ductus arteriosus in the premature newbornVineet Bhandari
Yale University School of Medicine, Department of Pediatrics, 333 Cedar St, PO Box 208064, New Haven, CT 06520 8064, USA
Pediatrics 123:669-73. 2009..In addition to prematurity and environmental factors, we hypothesized that genetic factors play a significant role in this condition... - Genetic susceptibility to retinopathy of prematurityMatthew J Bizzarro
Department of Pediatrics, Yale University School of Medicine, 333 Cedar St, New Haven, CT 06520-8064, USA
Pediatrics 118:1858-63. 2006..1% of the variance in liability for retinopathy of prematurity. CONCLUSION: In addition to prematurity and environmental factors, there is a strong genetic predisposition to retinopathy of prematurity... - Antibiotic-resistant organisms in the neonatal intensive care unitMatthew J Bizzarro
Division of Perinatal Medicine, Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520 8064, USA
Semin Perinatol 31:26-32. 2007.... - Seventy-five years of neonatal sepsis at Yale: 1928-2003Matthew J Bizzarro
Division of Perinatal Medicine, Yale University School of Medicine, New Haven, CT 06520-8064, USA
Pediatrics 116:595-602. 2005..The increase in late-onset sepsis in preterm infants who required prolonged intensive care indicates that strategies to prevent infection are urgently needed for this population of infants... - Partial exchange transfusion for polycythemia hyperviscosity syndromeBridget Hopewell
Yale University School of Medicine, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA
Am J Perinatol 28:557-64. 2011..PHS and PET are associated with significant complications. Well-designed studies with long-term follow up are needed to assess the risks and benefits of PET for PHS... - Granulicatella adiacens and Early-Onset Sepsis in NeonateMatthew J Bizzarro
Yale University School of Medicine, New Haven, Connecticut, USA
Emerg Infect Dis 17:1971-3. 2011..G. adiacens has been associated with bacteremia and endovascular, central nervous system, ocular, oral, bone and joint, and genitourinary infections (1-4)... - Antibiotic exposure in the newborn intensive care unit and the risk of necrotizing enterocolitisVanaja N Alexander
Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520 8064, USA
J Pediatr 159:392-7. 2011..To determine whether duration of antibiotic exposure is an independent risk factor for necrotizing enterocolitis (NEC)... - Prevention of central line associated bloodstream infections in critical care unitsSimon Li
Department of Pediatrics, Westchester Medical Center, Valhalla, New York, USA
Curr Opin Pediatr 23:85-90. 2011..Successful preventive strategies have recently been reported which have resulted in significant reductions in CLABSIs and their associated adverse outcomes... - Familial and genetic susceptibility to major neonatal morbidities in preterm twinsVineet Bhandari
Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520-8064, USA
Pediatrics 117:1901-6. 2006..These data demonstrate, for the first time, the significant genetic susceptibility for bronchopulmonary dysplasia in preterm infants... - A decline in the frequency of neonatal exchange transfusions and its effect on exchange-related morbidity and mortalityLaurie A Steiner
Department of Pediatrics, Yale University School of Medicine, 333 Cedar St, PO Box 208064, New Haven, CT 06520 8064, USA
Pediatrics 120:27-32. 2007..Our goal was to identify trends in patient demographics and indications for and complications related to neonatal exchange transfusion over a 21-year period in a single institution using a uniform protocol for performing the procedure... - Effects of hormones on fetal lung developmentMatthew J Bizzarro
Division of Perinatal Medicine, Department of Pediatrics, Yale University School of Medicine, Children's Hospital WP 493, 333 Cedar Street, P.O. Box 208064, New Haven, CT 06520-8064, USA
Obstet Gynecol Clin North Am 31:949-61, xii. 2004..Current controversies relate to the choice of glucocorticoid, optimal dosing regime, number of courses of therapy that should be administered, and, most importantly, potential toxicities...