Research Topics
| Kathleen BelangerSummaryAffiliation: Yale University Country: USA Publications
Research Grants
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Detail Information
Publications
Ambient air pollution and low birth weight in Connecticut and MassachusettsMichelle L Bell
School of Forestry and Environmental Studies, Yale University, New Haven, Connecticut 06511, USA
Environ Health Perspect 115:1118-24. 2007..Several studies have examined whether air pollution affects birth weight; however results vary and many studies were focused on Southern California or were conducted outside of the United States...
Effect of pregnancy on maternal asthma symptoms and medication useKathleen Belanger
Center for Perinatal Pediatric and Environmental Epidemiology, Yale University School of Public Health, New Haven, Connecticut 06510, USA
Obstet Gynecol 115:559-67. 2010..To examine whether factors related to the patient or her treatment influence asthma severity during pregnancy...
Effects of endotoxin exposure on childhood asthma risk are modified by a genetic polymorphism in ACAA1Joanne E Sordillo
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
BMC Med Genet 12:158. 2011..Polymorphisms in the endotoxin-mediated TLR4 pathway genes have been associated with asthma and atopy. We aimed to examine how genetic polymorphisms in innate immunity pathways interact with endotoxin to influence asthma risk in children...
Respiratory symptoms among infants at risk for asthma: association with surfactant protein A haplotypesMelinda M Pettigrew
Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, USA
BMC Med Genet 8:15. 2007....
Association of surfactant protein A polymorphisms with otitis media in infants at risk for asthmaMelinda M Pettigrew
Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, USA
BMC Med Genet 7:68. 2006....
Indoor combustion and asthmaKathleen Belanger
Yale University School of Medicine, Department of Epidemiology and Public Health, New Haven, CT 06510, USA
Immunol Allergy Clin North Am 28:507-19, vii. 2008..Some sources of combustion such as coal stoves have been more consistently associated with these outcomes than other sources such as woodstoves...
Association of indoor nitrogen dioxide exposure with respiratory symptoms in children with asthmaKathleen Belanger
Yale Center for Perinatal, Pediatric, and Environmental Epidemiology, New Haven, CT 06510, USA
Am J Respir Crit Care Med 173:297-303. 2006..Chronic exposure to indoor nitrogen dioxide (NO2) is a public health concern. Over half of U.S. households have a source of NO2, and experimental data suggest potential for adverse respiratory effects...
Symptoms of wheeze and persistent cough in the first year of life: associations with indoor allergens, air contaminants, and maternal history of asthmaKathleen Belanger
Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520 8034, USA
Am J Epidemiol 158:195-202. 2003..23, 95% CI: 1.01, 1.49). This appears to have been the first study to measure all of these home exposures (indoor allergens, nitrogen dioxide, fungi) and to prospectively measure the frequency of infant wheeze and persistent cough...
Exposure to NO2 and nitrous acid and respiratory symptoms in the first year of lifeRobert T van Strien
Yale School of Public Health, Center for Perinatal, Pediatric and Environmental Epidemiology, New Haven, Connecticut, USA
Epidemiology 15:471-8. 2004..We estimate the independent effects of exposure to nitrogen dioxide and nitrous acid on respiratory symptoms during the first year of life...
Indoor heating sources and respiratory symptoms in nonsmoking womenElizabeth W Triche
Department of Epidemiology and Public Health, Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Yale University School of Medicine, 60 College Street, New Haven, CT 06520 8034, USA
Epidemiology 16:377-84. 2005....
Asthma symptoms, severity, and drug therapy: a prospective study of effects on 2205 pregnanciesMichael B Bracken
Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06520, USA
Obstet Gynecol 102:739-52. 2003..To prospectively examine in pregnant women whether asthma or asthma therapy influenced preterm delivery, intrauterine grown restriction (IUGR), or birthweight...
Association of low-level ozone and fine particles with respiratory symptoms in children with asthmaJanneane F Gent
Center for Perinatal, Pediatric, and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Conn 06510, USA
JAMA 290:1859-67. 2003..Exposure to ozone and particulate matter of 2.5 microm or less (PM2.5) in air at levels above current US Environmental Protection Agency (EPA) standards is a risk factor for respiratory symptoms in children with asthma...
Caffeine metabolites in umbilical cord blood, cytochrome P-450 1A2 activity, and intrauterine growth restrictionLaura M Grosso
Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Yale University, New Haven, CT 06510, USA
Am J Epidemiol 163:1035-41. 2006..21, 95% confidence interval: 1.07, 1.37), suggesting that CYP1A2 activity, and not the absolute levels of paraxanthine, influences fetal growth. No associations were observed between caffeine or any metabolites and preterm delivery...
Levels of household mold associated with respiratory symptoms in the first year of life in a cohort at risk for asthmaJanneane F Gent
Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06510, USA
Environ Health Perspect 110:A781-6. 2002..We conclude that infants in this high-risk group who are exposed to high levels of Penicillium are at significant risk for wheeze and persistent cough...
Infant respiratory symptoms associated with indoor heating sourcesElizabeth W Triche
Center for Perinatal, Pediatric and Environmental Epidemology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06520, USA
Am J Respir Crit Care Med 166:1105-11. 2002..Fireplace use was not associated with any of the respiratory symptoms. Use of some heating sources appears related to respiratory symptoms in infants...
Association of pediatric asthma severity with exposure to common household dust allergensJanneane F Gent
Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, One Church Street, 6th Floor, New Haven, CT 06510, USA
Environ Res 109:768-74. 2009..Reducing exposure to household dust inhalant allergens has been proposed as one strategy to reduce asthma...
Low-level ozone exposure and respiratory symptoms in infantsElizabeth W Triche
Yale Center for Perinatal, Pediatric, and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06520 8034, USA
Environ Health Perspect 114:911-6. 2006..Environmental Protection Agency (EPA) ozone standards may not protect sensitive individuals. In this study we examined respiratory effects of ozone in infants who may be vulnerable, particularly if they are children of asthmatic mothers...
Dust mite, cockroach, cat, and dog allergen concentrations in homes of asthmatic children in the northeastern United States: impact of socioeconomic factors and population densityBrian P Leaderer
Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06520 8034, USA
Environ Health Perspect 110:419-25. 2002..Mite and cockroach allergens have distinct and opposite associations with socioeconomic factors and population density...
Symptoms and medication use in children with asthma and traffic-related sources of fine particle pollutionJanneane F Gent
Center for Perinatal, Pediatric and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06510, USA
Environ Health Perspect 117:1168-74. 2009..5))] is a potential factor in the exacerbation of asthma. National air quality particle standards consider total mass, not composition or sources, and may not protect against health impacts related to specific components...
Prenatal exposure to fine particulate matter and birth weight: variations by particulate constituents and sourcesMichelle L Bell
Yale University, School of Forestry and Environmental Studies, New Haven, CT 06511, USA
Epidemiology 21:884-91. 2010..Exposure to fine particles (PM2.5) during pregnancy has been linked to lower birth weight; however, the chemical composition of PM2.5 varies widely. The health effects of PM2.5 constituents are unknown...
Depression and serotonin reuptake inhibitor treatment as risk factors for preterm birthKimberly A Yonkers
Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, USA
Epidemiology 23:677-85. 2012..Studies that have attempted to separate effects of illness from treatment have been inconclusive. We sought to explore the separate effects of SRI use and major depressive episodes in pregnancy on risk of preterm birth...
Chocolate consumption in pregnancy and reduced likelihood of preeclampsiaElizabeth W Triche
Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Yale University, New Haven, CT 06510, USA
Epidemiology 19:459-64. 2008..Preeclampsia is a major pregnancy complication with cardiovascular manifestations. Recent studies suggest that chocolate consumption may benefit cardiovascular health...
Association of maternal caffeine consumption with decrements in fetal growthMichael B Bracken
Center for Perinatal, Pediatric and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, USA
Am J Epidemiol 157:456-66. 2003..3 g) cups of coffee)...
Relationship between birth weight and exposure to airborne fine particulate potassium and titanium during gestationMichelle L Bell
Yale University, School of Forestry and Environmental Studies, 195 Prospect St, New Haven, CT 06511, USA
Environ Res 117:83-9. 2012..Our results indicate that exposure to airborne potassium and titanium during pregnancy is associated with lower birth weight. Associations may relate to chemical components of sources producing K and Ti...
Effect of pregnancy and stage of pregnancy on asthma severity: a systematic reviewHelen L Kwon
Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06520-8034, USA
Am J Obstet Gynecol 190:1201-10. 2004..Large, well-conducted population-based studies that explore different aspects of asthma severity are needed to substantiate these preliminary results...
Association of asthma diagnosis, severity, symptoms, and treatment with risk of preeclampsiaElizabeth W Triche
Center for Perinatal, Pediatric, and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut, USA
Obstet Gynecol 104:585-93. 2004..This prospective study examines associations between aspects of asthma (diagnosis, severity, symptoms, and medication use) and risk of preeclampsia...
Review of research on residential mobility during pregnancy: consequences for assessment of prenatal environmental exposuresMichelle L Bell
Yale University, School of Forestry and Environmental Studies, New Haven, CT 06511, USA
J Expo Sci Environ Epidemiol 22:429-38. 2012..Future research should consider the implications of residential mobility during pregnancy in relation to the exposure's spatial heterogeneity and factors associated with the likelihood of moving and distance moved...
Does antidepressant use attenuate the risk of a major depressive episode in pregnancy?Kimberly A Yonkers
Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, USA
Epidemiology 22:848-54. 2011..We sought to estimate differences in the risk of developing a new major depressive episode among pregnant and postpartum women with recurrent illness who either did or did not use antidepressants...
Antibiotic exposure by 6 months and asthma and allergy at 6 years: Findings in a cohort of 1,401 US childrenKari R Risnes
Center for Perinatal, Pediatric, and Environmental Epidemiology, Yale University Schools of Public Health and Medicine, New Haven, Connecticut, USA
Am J Epidemiol 173:310-8. 2011..59 (95% CI: 1.10, 2.28). The results show that early antibiotic use was associated with asthma and allergy at 6 years of age, and that protopathic bias was unlikely to account for the main findings...
Genetic and perinatal risk factors for asthma onset and severity: a review and theoretical analysisMichael B Bracken
Center for Perinatal, Pediatric and Environmental Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, USA
Epidemiol Rev 24:176-89. 2002
Typical somatic symptoms of pregnancy and their impact on a diagnosis of major depressive disorderKimberly Ann Yonkers
Department of Psychiatry, Yale School of Medicine, New Haven, CT 06510, USA
Gen Hosp Psychiatry 31:327-33. 2009..We sought to determine whether trimester of pregnancy influences the ability to diagnose major depressive disorder (MDD)...
Household levels of nitrogen dioxide and pediatric asthma severityKathleen Belanger
Center for Perinatal, Pediatric and Environmental Epidemiology, Yale University School of Public Health, New Haven, CT 06510, USA
Epidemiology 24:320-30. 2013..S. households. We investigated the effects of indoor NO2 exposure on asthma severity among an ethnically and economically diverse sample of children, controlling for season and indoor allergen exposure...
Asthma prevalence among pregnant and childbearing-aged women in the United States: estimates from national health surveysHelen L Kwon
From the Center for Perinatal, Pediatric, andn Environmental Epidemiology, Yale University School of Public Health, New Haven, CT 06520, USA
Ann Epidemiol 13:317-24. 2003..Among women aged 18 to 24, the increase was three-fold, from 1.8% to 6.0%. CONCLUSION: The prevalence of asthma during pregnancy may be higher than previously estimated and appears to be continuing to increase...
Heterogeneity in assessing self-reports of caffeine exposure: implications for studies of health effectsMichael B Bracken
Perinatal Epidemiology Unit, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520 8034, USA
Epidemiology 13:165-71. 2002..Coffee and its metabolite caffeine are widely studied for their health effects but with inconclusive results. Caffeine is particularly difficult to assess, and therefore we explore heterogeneity of caffeine exposure...
Implementing provider-based sampling for the National Children's Study: opportunities and challengesKathleen Belanger
School of Public Health, Yale University Schools of Public Health and Medicine, New Haven, CT 06510, USA
Paediatr Perinat Epidemiol 27:20-6. 2013..The primary sampling unit was 105 study locations (typically a county). The secondary sampling unit was the geographic unit (segment), but this was subsequently perceived to be an inefficient strategy...
DNA adducts in human placenta exposed to ambient environment and passive cigarette smoke during pregnancyMrinal K Sanyal
Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University Medical School, New Haven, Connecticut, USA
Birth Defects Res A Clin Mol Teratol 79:289-94. 2007....
Indications contributing to the increasing cesarean delivery rateEmma L Barber
Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, New Haven, Connecticut, USA
Obstet Gynecol 118:29-38. 2011..To examine physician-documented indications for cesarean delivery in order to investigate the specific factors contributing to the increasing cesarean delivery rate...
Effects of posttraumatic stress disorder on pregnancy outcomesShari S Rogal
Yale University Department of Psychiatry, USA
J Affect Disord 102:137-43. 2007....
Prediction of residential pet and cockroach allergen levels using questionnaire informationUlrike Gehring
GSF-National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
Environ Health Perspect 112:834-9. 2004..Knowledge of past pet ownership can improve pet allergen exposure assessment by means of questionnaire. However, for epidemiologic purposes, measured concentrations of allergens are necessary...
The epidemiology of asthma during pregnancy: prevalence, diagnosis, and symptomsHelen L Kwon
Department of Epidemiology, Mailman School of Public Health, Columbia University, 722 West 168th Street, 7th Floor, New York, NY 10032, USA
Immunol Allergy Clin North Am 26:29-62. 2006....
Peak expiratory flow rate variability is not affected by home combustion sources in a group of nonsmoking womenWilliam S Beckett
Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
Arch Environ Occup Health 61:176-82. 2006..88; 95% CI = 1.59-5.21) and black or Hispanic ethnicity (OR = 2.02; 95% CI = 1.27-3.22), but was not associated with use of any supplementary home combustion sources among either asthmatic or nonasthmatic women...
Polymorphisms in the 5' region of the CD14 gene are associated with eczema in young childrenAugusto A Litonjua
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
J Allergy Clin Immunol 115:1056-62. 2005..Variants in the CD14 gene (CD14) are hypothesized to be associated with atopic disorders. However, most studies have only investigated one polymorphism in this gene...
Effect of fetal sex on airway lability in pregnant women with asthmaHelen L Kwon
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA
Am J Epidemiol 163:217-21. 2006..This difference persisted throughout pregnancy. Among pregnant asthmatic women, carrying a female fetus is associated with worse maternal asthma, as assessed by greater airway lability, than is carrying a male fetus...
Examination of racial imbalance for children in foster care: implications for trainingKathleen Belanger
School of Social Work, Stephen F Austin State University, P O Box 6104 SFA Station, Nacogdoches, TX 75961, USA
J Health Soc Policy 15:163-76. 2002....
Research Grants
- Effect of Air Pollution and Traffic on Birth OutcomesKathleen Belanger; Fiscal Year: 2009..If confirmed, reductions in specific types of air pollution may reduce these major infant health problems. ..
- Effect of Air Pollution and Traffic on Birth OutcomesMichelle L Bell; Fiscal Year: 2010..If confirmed, reductions in specific types of air pollution may reduce these major infant health problems. ..
