Research Topics
Genomes and GenesSpecies | Mert Ozan BahtiyarSummaryAffiliation: Yale University Country: USA Publications
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Publications
Cardiac changes in the intrauterine growth-restricted fetusMert Ozan Bahtiyar
Section of Maternal Fetal Medicine, Department of Obstetrics, Gynecology, and ReproductiveSciences, Yale University School of Medicine, 333 Cedar Street, POBox 208063, New Haven, CT 06520 8063, USA
Semin Perinatol 32:190-3. 2008..Overall, IUGR fetuses demonstrate progressive hemodynamic changes. It appears that there is an earlier and more pronounced right than left and diastolic than systolic fetal cardiac function deterioration in growth-restricted fetuses...
Is the rate of congenital heart defects detected by fetal echocardiography among pregnancies conceived by in vitro fertilization really increased?: a case-historical control studyMert Ozan Bahtiyar
Section of Maternal Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, 333 Cedar St, PO Box 208063, New Haven, CT 06520 8063, USA
J Ultrasound Med 29:917-22. 2010..We investigated the prenatal prevalence of congenital heart defects (CHDs) among in vitro fertilization (IVF) pregnancies at a referral program in the United States...- Prior cesarean delivery is not associated with an increased risk of stillbirth in a subsequent pregnancy: analysis of U.S. perinatal mortality data, 1995-1997Mert O Bahtiyar
Department of Obstetrics and Gynecology, Yale University, New Haven, CT 06520 8063, USA
Am J Obstet Gynecol 195:1373-8. 2006..This study investigated the association between prior cesarean delivery and unexplained intrauterine fetal demise at term in the United States... - Contrasting effects of chronic hypoxia and nitric oxide synthase inhibition on circulating angiogenic factors in a rat model of growth restrictionMert Ozan Bahtiyar
Division of Maternal and Fetal Medicine, Department of Obstetrics and Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520 8063, USA
Am J Obstet Gynecol 196:72.e1-6. 2007..We tested our hypothesis in a rodent model of intrauterine growth restriction induced by chronic hypoxia and NO inhibition with N(G)-nitro-L-arginine methyl ester (L-NAME)... - Prevalence of congenital heart defects in monochorionic/diamniotic twin gestations: a systematic literature reviewMert Ozan Bahtiyar
Section of Maternal Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA
J Ultrasound Med 26:1491-8. 2007..5% of all neonates. Recent literature points to a possible increase in the CHD prevalence among monochorionic/diamniotic (MC/DA) twin gestations. We hypothesized that MC/DA twin pregnancy is a risk factor for CHD... - Prenatal course of isolated muscular ventricular septal defects diagnosed only by color Doppler sonography: single-institution experienceMert Ozan Bahtiyar
Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520 8063, USA
J Ultrasound Med 27:715-20. 2008..The prevalence of these lesions is not yet completely described, and the frequency with which muscular VSDs resolve in utero has also not been extensively reported... 
Proteomic profiling of the amniotic fluid to detect inflammation, infection, and neonatal sepsisCatalin S Buhimschi
Department of Obstetrics, Gynecology and Reproductive Science, Yale University School of Medicine, New Haven, Connecticut, United States of America
PLoS Med 4:e18. 2007..Proteomic analysis of amniotic fluid shows the presence of biomarkers characteristic of intrauterine inflammation. We sought to validate prospectively the clinical utility of one such proteomic profile, the Mass Restricted (MR) score...- Multidimensional system biology: genetic markers and proteomic biomarkers of adverse pregnancy outcome in preterm birthCatalin S Buhimschi
Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut, USA
Am J Perinatol 25:175-87. 2008..Genomics and proteomics have emerged to provide a better comprehension of the pathophysiological conditions leading to preterm birth, thereby providing a perspective for improving neonatal outcome... - Fetal heart rate monitoring patterns in women with amniotic fluid proteomic profiles indicative of inflammationCatalin S Buhimschi
Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut, USA
Am J Perinatol 25:359-72. 2008..An abnormal FHR-MP can thus raise the level of awareness that a fetus with EONS may be born, but it is not a useful clinical indicator of the need for antibiotic treatment of the neonate... - A low vaginal "pool" amniotic fluid glucose measurement is a predictive but not a sensitive marker for infection in women with preterm premature rupture of membranesCatalin S Buhimschi
Department of Obstetrics, Gynecology, and Reproductive Science, Yale University, New Haven, CT 06520, USA
Am J Obstet Gynecol 194:309-16. 2006.... - Fetal adrenal gland volume and cortisol/dehydroepiandrosterone sulfate ratio in inflammation-associated preterm birthCatalin S Buhimschi
Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut 06520, USA
Obstet Gynecol 111:715-22. 2008..We sought to estimate the impact of intraamniotic inflammation on fetal adrenal gland volume and cortisol-to-dehydroepiandrosterone sulfate ratio (fetal stress ratio) in pregnancies complicated by preterm birth... - Normative postpartum intraabdominal pressure: potential implications in the diagnosis of abdominal compartment syndromeSonya S Abdel-Razeq
Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT, USA
Am J Obstet Gynecol 203:149.e1-4. 2010..We sought to establish normative values of intraabdominal pressure (IAP) in postpartum women with and without arterial hypertension... - Using proteomic analysis of the human amniotic fluid to identify histologic chorioamnionitisIrina A Buhimschi
Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut 06520, USA
Obstet Gynecol 111:403-12. 2008..To estimate the relationship between histologic chorioamnionitis and four amniotic fluid proteomic biomarkers characteristic of inflammation (defensins 2 and 1, calgranulins C and A)... - Relationships of maternal serum levels of vascular endothelial growth factor and tensile strength properties of the cervix in a rat model of chronic hypoxiaAnna K Sfakianaki
Department of Obstetrics, Gynecology, and Reproductive Science, Yale University School of Medicine, New Haven, CT 06520, USA
Am J Obstet Gynecol 198:223.e1-7. 2008..In this study, we sought to test the hypothesis that chronic hypoxia increases maternal serum levels of VEGF, which in turn cause measurable changes in the viscoelastic properties of the rat uterine cervix... - Stillbirth at term in women of advanced maternal age in the United States: when could the antenatal testing be initiated?Mert Ozan Bahtiyar
Yale University School of Medicine, Section of Maternal Fetal Medicine, New Haven, Connecticut, USA
Am J Perinatol 25:301-4. 2008..We concluded that AMA is an independent predictor of IUFD, and a strategy of antenatal testing in those > or = 40 years of age beginning at 38 weeks may be considered... - Nucleated red blood cells are a direct response to mediators of inflammation in newborns with early-onset neonatal sepsisAntonette T Dulay
Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520 8063, USA
Am J Obstet Gynecol 198:426.e1-9. 2008..We sought to determine whether fetal inflammation is associated with an elevation in neonatal NRBC count in the setting of inflammation-associated preterm birth... - The receptor for advanced glycation end products (RAGE) system in women with intraamniotic infection and inflammationIrina A Buhimschi
Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA
Am J Obstet Gynecol 196:181.e1-13. 2007..sRAGE, a competitive soluble RAGE receptor, inhibits RAGE ligands. Here we aimed to investigate the presence and changes in components of the RAGE system in women with intra-amniotic infection and inflammation... - Can postgraduate courses in Maternal-Fetal Medicine change clinical attitude?Errol R Norwitz
Division of Maternal Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences, Yale New Haven Hospital and Yale University School of Medicine, New Haven, CT 06520, USA
J Matern Fetal Neonatal Med 18:311-7. 2005..To investigate the effect of structured didactic lectures by leaders in the field of Maternal-Fetal Medicine on reported clinical decision-making... - Defining standards of care in maternal-fetal medicineErrol R Norwitz
Department of Obstetrics, Gynecology and Reproductive Sciences, Division of Maternal-Fetal Medicine, Yale-New Haven Hospital and Yale University School of Medicine, New Haven, CT, USA
Am J Obstet Gynecol 191:1491-6. 2004..CONCLUSION: Contemporary practice patterns for 7 controversial topics in obstetric medicine are described. Such surveys may be useful in defining standards of care in maternal-fetal medicine... - Proteomics: a novel methodology to complement prenatal diagnosis of chromosomal abnormalities and inherited human diseasesMert Ozan Bahtiyar
Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut 06520 8063, USA
Am J Perinatol 24:167-81. 2007..This article summarizes current technology and reviews the application of proteomics in diagnosis of genetic disorders during human pregnancy... - Fetal renal artery impedance as assessed by Doppler ultrasound in pregnancies complicated by intraamniotic inflammation and preterm birthHumberto Azpurua
Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA
Am J Obstet Gynecol 200:203.e1-11. 2009..The objective of the study was to evaluate the fetal renal artery impedance in the context of inflammation-associated preterm birth... - Interpretation of amniotic fluid white blood cell count in "bloody tap" amniocenteses in women with symptoms of preterm laborSonya S Abdel-Razeq
Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut, USA
Obstet Gynecol 116:344-54. 2010..To estimate whether blood-contaminated amniotic fluid affects the performance of white blood cell (WBC) count in diagnosing intraamniotic inflammation and infection... - Acceleration/ejection time ratio in the fetal pulmonary artery predicts fetal lung maturityHumberto Azpurua
Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT, USA
Am J Obstet Gynecol 203:40.e1-8. 2010..The aim of this study was to determine whether sonographic fetal pulmonary artery flow velocity waveforms correlate with amniotic fluid biomarkers of fetal lung maturity... - Single nucleotide polymorphisms in the human progesterone receptor gene and spontaneous preterm birth- Guoyang Luo
Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut, USA
Reprod Sci 15:147-55. 2008..5 kg/m(2) (relative risk, 10.8; 95% confidence interval, 1.4-82.6; P = .02). Maternal carriage of minor alleles of +331(G>A), +770(C>T), and +660(G> T) SNPs in the PR gene is not associated with spontaneous preterm birth... - Improving detection of fetal cardiac anomalies: a fetal echocardiogram for every fetus?Mert Ozan Bahtiyar
J Ultrasound Med 26:1639-41. 2007