Affiliation: Yale University
- Attenuation of the neuropsychiatric effects of ketamine with lamotrigine: support for hyperglutamatergic effects of N-methyl-D-aspartate receptor antagonistsA Anand
Department of Psychiatry, Yale University School of Medicine, West Haven, CT 06516, USA
Arch Gen Psychiatry 57:270-6. 2000..In this study, we tested the hypothesis that lamotrigine, a drug reported to inhibit glutamate release, will reduce the neuropsychiatric effects of ketamine in humans...
- Brain SPECT imaging of amphetamine-induced dopamine release in euthymic bipolar disorder patientsA Anand
Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06516, USA
Am J Psychiatry 157:1108-14. 2000..In this study, dopamine receptor imaging combined with a pharmacological challenge of amphetamine was used to assess both pre- and postsynaptic aspects of dopamine neurotransmission in euthymic bipolar disorder patients...
- Norepinephrine dysfunction in depressionA Anand
Department of Psychiatry, Yale University School of Medicine, New Haven, Conn, USA
J Clin Psychiatry 61:16-24. 2000....
- Transient depressive relapse induced by catecholamine depletion: potential phenotypic vulnerability marker?R M Berman
Connecticut Mental Health Center, Department of Psychiatry, Yale University School of Medicine, New Haven 06519, USA
Arch Gen Psychiatry 56:395-403. 1999..In our study, medication-free subjects with fully remitted major depression underwent a paradigm of catecholamine depletion, via use of the tyrosine hydroxylase inhibitor alpha-methylparatyrosine...
- Limited efficacy of ketoconazole in treatment-refractory major depressionR T Malison
Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA
J Clin Psychopharmacol 19:466-70. 1999..These findings suggest a limited efficacy for ketoconazole in patients with treatment-refractory major depression...
- No effect of light on basal glucagon levels in winter seasonal depressives and comparison subjectsD A Oren
Department of Veterans Affairs and Yale University, Mailstop 116A, 950 Campbell Avenue, West Haven, CT 06516, USA
Psychiatry Res 94:263-6. 2000..15 comparison subjects before and after at least 1 week of light treatment. No differences were seen between groups or conditions. There was no correlation between glucagon change and antidepressant response...
- Glutamate and GABA systems as targets for novel antidepressant and mood-stabilizing treatmentsJ H Krystal
Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
Mol Psychiatry 7:S71-80. 2002..Future research will be needed to develop and evaluate new agents with specific glutamate and GABA receptor targets in the treatment of mood disorders...