Tien L Huang


Affiliation: Xavier University of Louisiana
Country: USA


  1. Huang T, Vanden Eynde J, Mayence A, Collins M, Cushion M, Rattendi D, et al. Synthesis and SAR of alkanediamide-linked bisbenzamidines with anti-trypanosomal and anti-pneumocystis activity. Bioorg Med Chem Lett. 2009;19:5884-6 pubmed publisher
    ..carinii, and was non-cytotoxic in the A549 human lung carcinoma cell line. The inhibitory bioactivity was significantly reduced when the amidine groups in 4 were moved from the para to the meta positions or replaced with amides. ..
  2. Mottamal M, Zheng S, Huang T, Wang G. Histone deacetylase inhibitors in clinical studies as templates for new anticancer agents. Molecules. 2015;20:3898-941 pubmed publisher
  3. Vanden Eynde J, Mayence A, Mottamal M, Bacchi C, Yarlett N, Kaiser M, et al. Alkanediamide-Linked Bisbenzamidines Are Promising Antiparasitic Agents. Pharmaceuticals (Basel). 2016;9: pubmed publisher
    ..Several of the tested compounds are suitable leads for the development of improved antiparasitic agents. ..