Partha S Bhattacharjee

Summary

Affiliation: Xavier University of Louisiana
Country: USA

Publications

  1. pmc A human apolipoprotein E mimetic peptide effectively inhibits HSV-1 TK-positive and TK-negative acute epithelial keratitis in rabbits
    Partha S Bhattacharjee
    Department of Ophthalmology, Louisiana State University Health Sciences Center, New Orleans, Lousiana, USA
    Curr Eye Res 34:99-102. 2009
  2. pmc Effect of human apolipoprotein E genotype on the pathogenesis of experimental ocular HSV-1
    Partha S Bhattacharjee
    Department of Ophthalmology, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
    Exp Eye Res 87:122-30. 2008
  3. pmc Upregulation of mouse genes in HSV-1 latent TG after butyrate treatment implicates the multiple roles of the LAT-ICP0 locus
    Christian Clement
    Department of Ophthalmology, LSU Eye Center, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA
    Invest Ophthalmol Vis Sci 52:1770-9. 2011
  4. pmc HSV-1 latent rabbits shed viral DNA into their saliva
    James M Hill
    Department of Ophthalmology LSUHSC School of Medicine, 533 Bolivar Street, Room 3D13, New Orleans, LA 70112, USA
    Virol J 9:221. 2012
  5. pmc Effect of high versus low oral doses of valacyclovir on herpes simplex virus-1 DNA shedding into tears of latently infected rabbits
    Manish Kumar
    Department of Ophthalmology, Neuroscience Center of Excellence, School of Public Health, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
    Invest Ophthalmol Vis Sci 51:4703-6. 2010
  6. pmc Rabbit and mouse models of HSV-1 latency, reactivation, and recurrent eye diseases
    Jody M Webre
    Department of Ophthalmology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
    J Biomed Biotechnol 2012:612316. 2012
  7. pmc Heat-induced reactivation of HSV-1 in latent mice: upregulation in the TG of CD83 and other immune response genes and their LAT-ICP0 locus
    Christian Clement
    Department of Ophthalmology, LSU Eye Center, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA
    Invest Ophthalmol Vis Sci 50:2855-61. 2009
  8. pmc Microarray analysis of host gene expression for comparison between naïve and HSV-1 latent rabbit trigeminal ganglia
    Christian Clement
    Department of Ophthalmology, New Orleans, LA 70112, USA
    Mol Vis 14:1209-21. 2008
  9. doi request reprint Ocular HSV-1 latency, reactivation and recurrent disease
    Hassanain S Toma
    Louisiana State University Health Sciences Center, New Orleans, LA 70112 2234, USA
    Semin Ophthalmol 23:249-73. 2008
  10. pmc The high prevalence of herpes simplex virus type 1 DNA in human trigeminal ganglia is not a function of age or gender
    James M Hill
    Department of Ophthalmology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA
    J Virol 82:8230-4. 2008

Collaborators

Detail Information

Publications23

  1. pmc A human apolipoprotein E mimetic peptide effectively inhibits HSV-1 TK-positive and TK-negative acute epithelial keratitis in rabbits
    Partha S Bhattacharjee
    Department of Ophthalmology, Louisiana State University Health Sciences Center, New Orleans, Lousiana, USA
    Curr Eye Res 34:99-102. 2009
    ....
  2. pmc Effect of human apolipoprotein E genotype on the pathogenesis of experimental ocular HSV-1
    Partha S Bhattacharjee
    Department of Ophthalmology, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
    Exp Eye Res 87:122-30. 2008
    ..This is the first report linking a human gene, apoE4, as a risk factor for ocular herpes pathogenesis in a transgenic mouse model...
  3. pmc Upregulation of mouse genes in HSV-1 latent TG after butyrate treatment implicates the multiple roles of the LAT-ICP0 locus
    Christian Clement
    Department of Ophthalmology, LSU Eye Center, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA
    Invest Ophthalmol Vis Sci 52:1770-9. 2011
    ..To determine host response by gene expression in HSV-1 latent trigeminal ganglia (TG) after sodium butyrate (NaBu) treatment...
  4. pmc HSV-1 latent rabbits shed viral DNA into their saliva
    James M Hill
    Department of Ophthalmology LSUHSC School of Medicine, 533 Bolivar Street, Room 3D13, New Orleans, LA 70112, USA
    Virol J 9:221. 2012
    ..This study used real-time PCR to quantify HSV-1 DNA in the saliva and tears of rabbits latent with HSV-1 McKrae...
  5. pmc Effect of high versus low oral doses of valacyclovir on herpes simplex virus-1 DNA shedding into tears of latently infected rabbits
    Manish Kumar
    Department of Ophthalmology, Neuroscience Center of Excellence, School of Public Health, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
    Invest Ophthalmol Vis Sci 51:4703-6. 2010
    ..To assess the effect of high doses of valacyclovir (VCV) on HSV-1 DNA shedding into tears of latently infected rabbits...
  6. pmc Rabbit and mouse models of HSV-1 latency, reactivation, and recurrent eye diseases
    Jody M Webre
    Department of Ophthalmology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
    J Biomed Biotechnol 2012:612316. 2012
    ..This paper is pertinent but not intended to be all inclusive. We will give examples of key papers that have reported novel discoveries related to the review topics...
  7. pmc Heat-induced reactivation of HSV-1 in latent mice: upregulation in the TG of CD83 and other immune response genes and their LAT-ICP0 locus
    Christian Clement
    Department of Ophthalmology, LSU Eye Center, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA
    Invest Ophthalmol Vis Sci 50:2855-61. 2009
    ..To determine changes in host gene expression in HSV-1 latent trigeminal ganglia (TG) after hyperthermic stress...
  8. pmc Microarray analysis of host gene expression for comparison between naïve and HSV-1 latent rabbit trigeminal ganglia
    Christian Clement
    Department of Ophthalmology, New Orleans, LA 70112, USA
    Mol Vis 14:1209-21. 2008
    ....
  9. doi request reprint Ocular HSV-1 latency, reactivation and recurrent disease
    Hassanain S Toma
    Louisiana State University Health Sciences Center, New Orleans, LA 70112 2234, USA
    Semin Ophthalmol 23:249-73. 2008
    ..This review will highlight basic HSV-1 virology, and will compare the animal models of latency, reactivation, and recurrent ocular disease to the current clinical data...
  10. pmc The high prevalence of herpes simplex virus type 1 DNA in human trigeminal ganglia is not a function of age or gender
    James M Hill
    Department of Ophthalmology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA
    J Virol 82:8230-4. 2008
    ..This is the first study that provides statistical analysis that documents that the prevalence of HSV-1 DNA in the human TG is not a function of either gender or age...
  11. doi request reprint Effective treatment of ocular HSK with a human apolipoprotein E mimetic peptide in a mouse eye model
    Partha S Bhattacharjee
    Departments of Ophthalmology, School of Public Health, LouisianaState University Health Sciences Center, New Orleans, Louisiana 70112, USA
    Invest Ophthalmol Vis Sci 49:4263-8. 2008
    ....
  12. pmc Sodium butyrate: a chemical inducer of in vivo reactivation of herpes simplex virus type 1 in the ocular mouse model
    Donna M Neumann
    Department of Ophthalmology LSU Eye Center of Excellence, Louisiana State University Health Sciences Center at New Orleans, New Orleans, Louisiana 70112, USA
    J Virol 81:6106-10. 2007
    ....
  13. pmc Ocular herpes simplex virus: how are latency, reactivation, recurrent disease and therapy interrelated?
    Lena J Al-Dujaili
    Department of Ophthalmology, Louisiana State University Health Sciences Center, New Orleans, USA
    Future Microbiol 6:877-907. 2011
    ..Here, we review HSV-1 latent infections, reactivation, recurrent disease and antiviral therapies for the ocular HSV diseases...
  14. ncbi request reprint Apolipoprotein E modulates establishment of HSV-1 latency and survival in a mouse ocular model
    Partha S Bhattacharjee
    Department of Ophthalmology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA
    Curr Eye Res 31:703-8. 2006
    ..To evaluate and compare the neuroinvasiveness and neurovirulence after ocular HSV-1 infection in ApoE knockout (ApoE-/-) and control C57BL/6 (ApoE+/+) mice...
  15. pmc In vitro synergism of trifluorothymidine and ganciclovir against HSV-1
    Jeffery A Hobden
    Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA
    Invest Ophthalmol Vis Sci 52:830-3. 2011
    ..To determine whether trifluorothymidine (TFT) and ganciclovir (GCV) are synergistic against herpes simplex virus type 1 (HSV-1)...
  16. pmc Ocular herpes simplex virus type 1: is the cornea a reservoir for viral latency or a fast pit stop?
    David P Kennedy
    Department of Ophthalmology, Louisiana State University Health Sciences Center, New Orleans, LA 70112 2234, USA
    Cornea 30:251-9. 2011
    ..To present a review supporting and refuting evidence from mouse, rabbit, nonhuman primate, and human studies of herpes simplex virus type 1 (HSV-1) concerning corneal latency...
  17. pmc Clinical and antiviral efficacy of an ophthalmic formulation of dexamethasone povidone-iodine in a rabbit model of adenoviral keratoconjunctivitis
    Christian Clement
    Department of Ophthalmology, School of Public Health, Neuroscience Center, Louisiana State University, New Orleans, LA 70112, USA
    Invest Ophthalmol Vis Sci 52:339-44. 2011
    ..To determine the efficacy of a new formulation of topical dexamethasone 0.1%/povidone-iodine 0.4% (FST-100) in reducing clinical symptoms and infectious viral titers in a rabbit model of adenoviral keratoconjunctivitis...
  18. pmc In vivo changes in the patterns of chromatin structure associated with the latent herpes simplex virus type 1 genome in mouse trigeminal ganglia can be detected at early times after butyrate treatment
    Donna M Neumann
    Department of Ophthalmology LSU Eye Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA
    J Virol 81:13248-53. 2007
    ..5 h and 1 h post-butyrate treatment, respectively. This is the first study to combine in vivo reactivation with the examination of the HSV-1 genome through ChIP assays at early times after the introduction of in vivo reactivation stimuli...
  19. pmc Apolipoprotein E alleles can contribute to the pathogenesis of numerous clinical conditions including HSV-1 corneal disease
    James M Hill
    Department of Ophthalmology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
    Exp Eye Res 84:801-11. 2007
    ..While many clinical investigations have been reported and, to a lesser extent, transgenic mouse studies have been conducted, no specific mechanisms of how ApoE induces or alters clinical disease are known...
  20. pmc Acyclovir or Aβ42 peptides attenuate HSV-1-induced miRNA-146a levels in human primary brain cells
    Walter J Lukiw
    LSU Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, 2020 Gravier Street, Suite 904, New Orleans, LA 70112 2272, USA
    Neuroreport 21:922-7. 2010
    ....
  21. doi request reprint The antimicrobial agent C31G is effective for therapy for HSV-1 ocular keratitis in the rabbit eye model
    James M Hill
    Louisiana State University Health Sciences Center LSUHSC, Department of Ophthalmology, 533 Bolivar Street, New Orleans, LA 70112, United States Department of Microbiology, LSUHSC, United States Neuroscience Center, LSUHSC, 2020 Gravier Street, 8th Floor, New Orleans, LA 70112, United States Department of Pharmacology, LSUHSC, 1901 Perdido Street, New Orleans, LA 70112, United States Electronic address
    Antiviral Res 100:14-9. 2013
    ..The vehicle control scores were significantly higher and did not effectively treat HSV-1 keratitis. C31G has the potential to be used to treat herpetic keratitis as well as other herpetic topical lesions in humans. ..
  22. pmc High-glucose-induced endothelial cell injury is inhibited by a Peptide derived from human apolipoprotein E
    Partha S Bhattacharjee
    Department of Biology, Xavier University of Louisiana, New Orleans, Louisiana, USA
    PLoS ONE 7:e52152. 2012
    ..Thus, strategies targeting ECM-degrading enzymes could be therapeutically beneficial for treating diabetic retinopathy...
  23. ncbi request reprint Overlapping subdeletions within a 348-bp in the 5' exon of the LAT region that facilitates epinephrine-induced reactivation of HSV-1 in the rabbit ocular model do not further define a functional element
    Partha S Bhattacharjee
    LSU Eye Center, Department of Ophthalmology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
    Virology 312:151-8. 2003
    ....