Research Topics
| Partha S BhattacharjeeSummaryAffiliation: Xavier University of Louisiana Country: USA Publications
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Detail Information
Publications
A human apolipoprotein E mimetic peptide effectively inhibits HSV-1 TK-positive and TK-negative acute epithelial keratitis in rabbitsPartha S Bhattacharjee
Department of Ophthalmology, Louisiana State University Health Sciences Center, New Orleans, Lousiana, USA
Curr Eye Res 34:99-102. 2009....- Effect of human apolipoprotein E genotype on the pathogenesis of experimental ocular HSV-1Partha S Bhattacharjee
Department of Ophthalmology, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
Exp Eye Res 87:122-30. 2008..This is the first report linking a human gene, apoE4, as a risk factor for ocular herpes pathogenesis in a transgenic mouse model... - Upregulation of mouse genes in HSV-1 latent TG after butyrate treatment implicates the multiple roles of the LAT-ICP0 locusChristian Clement
Department of Ophthalmology, LSU Eye Center, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA
Invest Ophthalmol Vis Sci 52:1770-9. 2011..To determine host response by gene expression in HSV-1 latent trigeminal ganglia (TG) after sodium butyrate (NaBu) treatment... - Effect of high versus low oral doses of valacyclovir on herpes simplex virus-1 DNA shedding into tears of latently infected rabbitsManish Kumar
Department of Ophthalmology, Neuroscience Center of Excellence, School of Public Health, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
Invest Ophthalmol Vis Sci 51:4703-6. 2010..To assess the effect of high doses of valacyclovir (VCV) on HSV-1 DNA shedding into tears of latently infected rabbits... - Heat-induced reactivation of HSV-1 in latent mice: upregulation in the TG of CD83 and other immune response genes and their LAT-ICP0 locusChristian Clement
Department of Ophthalmology, LSU Eye Center, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA
Invest Ophthalmol Vis Sci 50:2855-61. 2009..To determine changes in host gene expression in HSV-1 latent trigeminal ganglia (TG) after hyperthermic stress... - Microarray analysis of host gene expression for comparison between naïve and HSV-1 latent rabbit trigeminal gangliaChristian Clement
Department of Ophthalmology, New Orleans, LA 70112, USA
Mol Vis 14:1209-21. 2008.... 
Effective treatment of ocular HSK with a human apolipoprotein E mimetic peptide in a mouse eye modelPartha S Bhattacharjee
Departments of Ophthalmology, School of Public Health, LouisianaState University Health Sciences Center, New Orleans, Louisiana 70112, USA
Invest Ophthalmol Vis Sci 49:4263-8. 2008....- The high prevalence of herpes simplex virus type 1 DNA in human trigeminal ganglia is not a function of age or genderJames M Hill
Department of Ophthalmology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA
J Virol 82:8230-4. 2008..This is the first study that provides statistical analysis that documents that the prevalence of HSV-1 DNA in the human TG is not a function of either gender or age... - Ocular HSV-1 latency, reactivation and recurrent diseaseHassanain S Toma
Louisiana State University Health Sciences Center, New Orleans, LA 70112 2234, USA
Semin Ophthalmol 23:249-73. 2008..This review will highlight basic HSV-1 virology, and will compare the animal models of latency, reactivation, and recurrent ocular disease to the current clinical data... 
Apolipoprotein E modulates establishment of HSV-1 latency and survival in a mouse ocular modelPartha S Bhattacharjee
Department of Ophthalmology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA
Curr Eye Res 31:703-8. 2006..To evaluate and compare the neuroinvasiveness and neurovirulence after ocular HSV-1 infection in ApoE knockout (ApoE-/-) and control C57BL/6 (ApoE+/+) mice...- Ocular herpes simplex virus: how are latency, reactivation, recurrent disease and therapy interrelated?Lena J Al-Dujaili
Department of Ophthalmology, Louisiana State University Health Sciences Center, New Orleans, USA
Future Microbiol 6:877-907. 2011..Here, we review HSV-1 latent infections, reactivation, recurrent disease and antiviral therapies for the ocular HSV diseases... - Sodium butyrate: a chemical inducer of in vivo reactivation of herpes simplex virus type 1 in the ocular mouse modelDonna M Neumann
Department of Ophthalmology LSU Eye Center of Excellence, Louisiana State University Health Sciences Center at New Orleans, New Orleans, Louisiana 70112, USA
J Virol 81:6106-10. 2007.... - In vitro synergism of trifluorothymidine and ganciclovir against HSV-1Jeffery A Hobden
Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA
Invest Ophthalmol Vis Sci 52:830-3. 2011..To determine whether trifluorothymidine (TFT) and ganciclovir (GCV) are synergistic against herpes simplex virus type 1 (HSV-1)... - Ocular herpes simplex virus type 1: is the cornea a reservoir for viral latency or a fast pit stop?David P Kennedy
Department of Ophthalmology, Louisiana State University Health Sciences Center, New Orleans, LA 70112 2234, USA
Cornea 30:251-9. 2011..To present a review supporting and refuting evidence from mouse, rabbit, nonhuman primate, and human studies of herpes simplex virus type 1 (HSV-1) concerning corneal latency... - In vivo changes in the patterns of chromatin structure associated with the latent herpes simplex virus type 1 genome in mouse trigeminal ganglia can be detected at early times after butyrate treatmentDonna M Neumann
Department of Ophthalmology LSU Eye Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA
J Virol 81:13248-53. 2007..5 h and 1 h post-butyrate treatment, respectively. This is the first study to combine in vivo reactivation with the examination of the HSV-1 genome through ChIP assays at early times after the introduction of in vivo reactivation stimuli... - Clinical and antiviral efficacy of an ophthalmic formulation of dexamethasone povidone-iodine in a rabbit model of adenoviral keratoconjunctivitisChristian Clement
Department of Ophthalmology, School of Public Health, Neuroscience Center, Louisiana State University, New Orleans, LA 70112, USA
Invest Ophthalmol Vis Sci 52:339-44. 2011..To determine the efficacy of a new formulation of topical dexamethasone 0.1%/povidone-iodine 0.4% (FST-100) in reducing clinical symptoms and infectious viral titers in a rabbit model of adenoviral keratoconjunctivitis... - HSV-1 latent rabbits shed viral DNA into their salivaJames M Hill
Department of Ophthalmology LSUHSC School of Medicine, 533 Bolivar Street, Room 3D13, New Orleans, LA 70112, USA
Virol J 9:221. 2012..This study used real-time PCR to quantify HSV-1 DNA in the saliva and tears of rabbits latent with HSV-1 McKrae... - Rabbit and mouse models of HSV-1 latency, reactivation, and recurrent eye diseasesJody M Webre
Department of Ophthalmology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
J Biomed Biotechnol 2012:612316. 2012..This paper is pertinent but not intended to be all inclusive. We will give examples of key papers that have reported novel discoveries related to the review topics... - Acyclovir or Aβ42 peptides attenuate HSV-1-induced miRNA-146a levels in human primary brain cellsWalter J Lukiw
LSU Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, 2020 Gravier Street, Suite 904, New Orleans, LA 70112 2272, USA
Neuroreport 21:922-7. 2010.... - Apolipoprotein E alleles can contribute to the pathogenesis of numerous clinical conditions including HSV-1 corneal diseaseJames M Hill
Department of Ophthalmology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
Exp Eye Res 84:801-11. 2007..While many clinical investigations have been reported and, to a lesser extent, transgenic mouse studies have been conducted, no specific mechanisms of how ApoE induces or alters clinical disease are known... - High-glucose-induced endothelial cell injury is inhibited by a Peptide derived from human apolipoprotein EPartha S Bhattacharjee
Department of Biology, Xavier University of Louisiana, New Orleans, Louisiana, USA
PLoS ONE 7:e52152. 2012..Thus, strategies targeting ECM-degrading enzymes could be therapeutically beneficial for treating diabetic retinopathy... - Overlapping subdeletions within a 348-bp in the 5' exon of the LAT region that facilitates epinephrine-induced reactivation of HSV-1 in the rabbit ocular model do not further define a functional elementPartha S Bhattacharjee
LSU Eye Center, Department of Ophthalmology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
Virology 312:151-8. 2003....