Karen A TourianSummaryAffiliation: Wyeth Research Country: USA Publications
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Publications
Desvenlafaxine 50 and 100 mg/d in the treatment of major depressive disorder: an 8-week, phase III, multicenter, randomized, double-blind, placebo-controlled, parallel-group trial and a post hoc pooled analysis of three studiesKaren A Tourian
Wyeth Research, Paris, France
Clin Ther 31:1405-23. 2009..Although a number of effective antidepressants are available, the need for new medications that are effective and well tolerated remains...
A randomized, double-blind, placebo-controlled trial of desvenlafaxine succinate in the treatment of major depressive disorderLucia Septien Velez
Wyeth Research, Paris, France
Int Clin Psychopharmacol 22:338-47. 2007..These data provide support for the efficacy and safety of desvenlafaxine in the treatment of major depressive disorder...
Analysis of the effect of desvenlafaxine on anxiety symptoms associated with major depressive disorder: pooled data from 9 short-term, double-blind, placebo-controlled trialsKaren A Tourian
Wyeth, a company of the Pfizer Group, Paris, France
CNS Spectr 15:187-93. 2010..This analysis evaluated the effects of the serotonin-norepinephrine reuptake inhibitor, desvenlafaxine (administered as desvenlafaxine succinate), on anxiety symptoms associated with depression...
Retrospective analysis of suicidality in patients treated with the antidepressant desvenlafaxineKaren A Tourian
Wyeth, a company of the Pfizer Group, Division Wyeth Research, Paris, France
J Clin Psychopharmacol 30:411-6. 2010..No evidence of a signal for increased suicidality was detected in adult patients treated with desvenlafaxine in short-term MDD trials. As suicidal events were extremely rare, a true increased risk cannot be ruled out...
Desvenlafaxine and weight change in major depressive disorderKaren A Tourian
Wyeth Research, Collegeville, Pennsylvania and Wyeth Research, Paris, France Drs Tourian and Leurent are currently with Wyeth, a company of the Pfizer Group, Paris, France, and Drs Graepel and Ninan are currently with Pfizer Inc, Collegeville, Pennsylvania
Prim Care Companion J Clin Psychiatry 12:PCC.08m00746. 2010..To characterize weight change during short- and longer-term treatment with desvenlafaxine (administered as desvenlafaxine succinate) for major depressive disorder (MDD)...
