James H Pickar

Summary

Affiliation: Wyeth Research
Country: USA

Publications

  1. doi Endometrial effects of a tissue selective estrogen complex containing bazedoxifene/conjugated estrogens as a menopausal therapy
    James H Pickar
    Wyeth Research, Collegeville, Pennsylvania 19101, USA
    Fertil Steril 92:1018-24. 2009
  2. ncbi Do journals have a publication bias?
    James H Pickar
    Wyeth Research, Philadelphia, PA, USA
    Maturitas 57:16-9. 2007
  3. ncbi Endometrial effects of lower doses of conjugated equine estrogens and medroxyprogesterone acetate: two-year substudy results
    James H Pickar
    Wyeth Research, Philadelphia, Pennsylvania 19101 2528, USA
    Fertil Steril 80:1234-40. 2003
  4. ncbi Endometrial effects of bazedoxifene acetate, a novel selective estrogen receptor modulator, in postmenopausal women
    Sheila Ronkin
    Wyeth Research, Collegeville, Pennsylvania 19426, USA
    Obstet Gynecol 105:1397-404. 2005
  5. ncbi Estrogens in postmenopausal women: recent insights
    Ginger D Constantine
    Wyeth Research, 500 Arcola Road, Collegeville, PA 19426, USA
    Curr Opin Pharmacol 3:626-34. 2003
  6. ncbi Body composition during treatment with conjugated estrogens with and without medroxyprogesterone acetate: analysis of the women's Health, Osteoporosis, Progestin, Estrogen (HOPE) trial
    Ian H Thorneycroft
    Department of Obstetrics and Gynecology, University of South Alabama, Mobile, AL, USA
    Am J Obstet Gynecol 197:137.e1-7. 2007
  7. ncbi Identification of a novel estrogen-regulated gene, EIG121, induced by hormone replacement therapy and differentially expressed in type I and type II endometrial cancer
    Lei Deng
    Department of Pathology, University of Texas M D Anderson Cancer Center, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA
    Clin Cancer Res 11:8258-64. 2005
  8. ncbi Bone response to treatment with lower doses of conjugated estrogens with and without medroxyprogesterone acetate in early postmenopausal women
    Robert Lindsay
    Helen Hayes Hospital, Route 9 W, West Haverstraw, NY 10993, USA
    Osteoporos Int 16:372-9. 2005
  9. ncbi Body mass index does not influence response to treatment, nor does body weight change with lower doses of conjugated estrogens and medroxyprogesterone acetate in early postmenopausal women
    Wulf H Utian
    Rapid Medical Research, Cleveland, Ohio, USA
    Menopause 11:306-14. 2004
  10. ncbi Coordinate regulation of the production and signaling of retinoic acid by estrogen in the human endometrium
    Lei Deng
    Department of Integrative Biology and Pharmacology, University of Texas Houston Health Science Center, Houston, Texas 77030, USA
    J Clin Endocrinol Metab 88:2157-63. 2003

Collaborators

Detail Information

Publications12

  1. doi Endometrial effects of a tissue selective estrogen complex containing bazedoxifene/conjugated estrogens as a menopausal therapy
    James H Pickar
    Wyeth Research, Collegeville, Pennsylvania 19101, USA
    Fertil Steril 92:1018-24. 2009
    ..To evaluate the endometrial safety of a tissue selective estrogen complex (TSEC; pairing of a selective estrogen receptor modulator [SERM] with estrogens) composed of bazedoxifene/conjugated estrogens (BZA/CE) in postmenopausal women...
  2. ncbi Do journals have a publication bias?
    James H Pickar
    Wyeth Research, Philadelphia, PA, USA
    Maturitas 57:16-9. 2007
    ..Additionally, the routine practice of a journal providing copies of articles and press releases related to those articles in advance of the journal's publication and general availability requires evaluation...
  3. ncbi Endometrial effects of lower doses of conjugated equine estrogens and medroxyprogesterone acetate: two-year substudy results
    James H Pickar
    Wyeth Research, Philadelphia, Pennsylvania 19101 2528, USA
    Fertil Steril 80:1234-40. 2003
    ..To determine the endometrial safety of 2 years of treatment with lower doses of continuous combined conjugated equine estrogens (CEE) and medroxyprogesterone acetate (MPA)...
  4. ncbi Endometrial effects of bazedoxifene acetate, a novel selective estrogen receptor modulator, in postmenopausal women
    Sheila Ronkin
    Wyeth Research, Collegeville, Pennsylvania 19426, USA
    Obstet Gynecol 105:1397-404. 2005
    ..To assess the endometrial effects of bazedoxifene acetate in healthy postmenopausal women...
  5. ncbi Estrogens in postmenopausal women: recent insights
    Ginger D Constantine
    Wyeth Research, 500 Arcola Road, Collegeville, PA 19426, USA
    Curr Opin Pharmacol 3:626-34. 2003
    ..Ongoing investigations into different formulations and dosing options, as well as genetic factors that might influence the response to therapy, should provide valuable information...
  6. ncbi Body composition during treatment with conjugated estrogens with and without medroxyprogesterone acetate: analysis of the women's Health, Osteoporosis, Progestin, Estrogen (HOPE) trial
    Ian H Thorneycroft
    Department of Obstetrics and Gynecology, University of South Alabama, Mobile, AL, USA
    Am J Obstet Gynecol 197:137.e1-7. 2007
    ..The objective of the study was to determine the effects of several doses of conjugated estrogens (CE) and CE plus medroxyprogesterone acetate (MPA) on body composition (BC)...
  7. ncbi Identification of a novel estrogen-regulated gene, EIG121, induced by hormone replacement therapy and differentially expressed in type I and type II endometrial cancer
    Lei Deng
    Department of Pathology, University of Texas M D Anderson Cancer Center, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA
    Clin Cancer Res 11:8258-64. 2005
    ..Here, we describe the expression pattern of a novel estrogen-induced gene, EIG121, in distinct types of endometrial cancer...
  8. ncbi Bone response to treatment with lower doses of conjugated estrogens with and without medroxyprogesterone acetate in early postmenopausal women
    Robert Lindsay
    Helen Hayes Hospital, Route 9 W, West Haverstraw, NY 10993, USA
    Osteoporos Int 16:372-9. 2005
    ..In summary, continued bone loss among early postmenopausal women treated with lower doses of CE or CE/MPA is uncommon...
  9. ncbi Body mass index does not influence response to treatment, nor does body weight change with lower doses of conjugated estrogens and medroxyprogesterone acetate in early postmenopausal women
    Wulf H Utian
    Rapid Medical Research, Cleveland, Ohio, USA
    Menopause 11:306-14. 2004
    ....
  10. ncbi Coordinate regulation of the production and signaling of retinoic acid by estrogen in the human endometrium
    Lei Deng
    Department of Integrative Biology and Pharmacology, University of Texas Houston Health Science Center, Houston, Texas 77030, USA
    J Clin Endocrinol Metab 88:2157-63. 2003
    ..This coordinate mechanism may play a role in the antiproliferative effects that counterbalance the estrogen-induced endometrial proliferation...
  11. ncbi Menopausal symptoms in older women and the effects of treatment with hormone therapy
    Vanessa M Barnabei
    Medical College of Wisconsin, Milwaukee 53226, USA
    Obstet Gynecol 100:1209-18. 2002
    ..The frequency and severity of such symptoms and response to hormone therapy in older women have not been well documented...
  12. ncbi Effect of lower doses of conjugated equine estrogens with and without medroxyprogesterone acetate on bone in early postmenopausal women
    Robert Lindsay
    Internal Medicine, Helen Hayes Hospital, Rte 9W, West Haverstraw, NY 10993, USA
    JAMA 287:2668-76. 2002
    ..This lower-dose therapy's protection against loss of bone mineral density (BMD) associated with menopause has not been thoroughly investigated...