Research Topics
| William OhSummaryAffiliation: Women and Infants' Hospital Country: USA Publications
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Publications
Early onset neonatal group B streptococcal sepsisWilliam Oh
Department of Pediatrics, Alpert Medical School, Brown University, Providence, RI, USA
Am J Perinatol 30:143-7. 2013..5 to 0.3/1,000 live births over the past three decades. Some women may have unknown GBS status. The American Academy of Pediatrics has developed an algorithm as guidance for the management of the newborns...
Fluid and electrolyte management of very low birth weight infantsWilliam Oh
Department of Pediatrics, Alpert Medical School of Brown University, Providence, RI 02912, USA
Pediatr neonatol 53:329-33. 2012..The review also describes the principles of fluid and electrolyte management of infants with BPD, which includes the strategy of providing adequate nutrition to promote normal growth...
Influence of clinical status on the association between plasma total and unbound bilirubin and death or adverse neurodevelopmental outcomes in extremely low birth weight infantsW Oh
Warren Alpert Medical School of Brown University, RI, USA
Acta Paediatr 99:673-8. 2010..To assess the influence of clinical status on the association between total plasma bilirubin and unbound bilirubin on death or adverse neurodevelopmental outcomes at 18-22 months corrected age in extremely low birth weight infants...
Association between fluid intake and weight loss during the first ten days of life and risk of bronchopulmonary dysplasia in extremely low birth weight infantsWilliam Oh
Neonatal Research Center, Bethesda, MD, USA
J Pediatr 147:786-90. 2005..To demonstrate the association between fluid intake and weight loss during the first 10 days of life and the risk of bronchopulmonary dysplasia (BPD) in extremely low birth weight (ELBW) infants...
Association between peak serum bilirubin and neurodevelopmental outcomes in extremely low birth weight infantsWilliam Oh
Women and Infants Hospital of Rhode Island Brown University, Providence, Rhode Island 02905, USA
Pediatrics 112:773-9. 2003..To assess the association between peak total serum bilirubin (PSB) levels during the first 2 weeks of life and neurodevelopmental outcomes of extremely low birth weight (ELBW) infants at 18 to 22 months' postmenstrual age...
Effects of delayed cord clamping in very-low-birth-weight infantsW Oh
Department of Pediatrics, Women and Infants Hospital, 101 Dudley Street, Providence, RI 02905, USA
J Perinatol 31:S68-71. 2011..Delayed cord clamping (DCC) may be beneficial in very-preterm and very-low-birth-weight infants...
Cytokines and neurodevelopmental outcomes in extremely low birth weight infantsWaldemar A Carlo
Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35233 7335, USA
J Pediatr 159:919-25.e3. 2011....
Outcome of term infants using apgar scores at 10 minutes following hypoxic-ischemic encephalopathyAbbot R Laptook
Department of Pediatrics, Women and Infants Hospital of Rhode Island, Providence, Rhode Island 02906, USA
Pediatrics 124:1619-26. 2009..The objective of this study was to determine whether Apgar scores at 10 minutes are associated with death or disability in early childhood after perinatal hypoxic-ischemic encephalopathy...
Outcomes of safety and effectiveness in a multicenter randomized, controlled trial of whole-body hypothermia for neonatal hypoxic-ischemic encephalopathySeetha Shankaran
Department of Pediatrics, Wayne State University School of Medicine, Detroit, Michigan, USA
Pediatrics 122:e791-8. 2008..Whole-body hypothermia reduced the frequency of death or moderate/severe disabilities in neonates with hypoxic-ischemic encephalopathy in a randomized, controlled multicenter trial...
Predicting time to hospital discharge for extremely preterm infantsSusan R Hintz
Department of Pediatrics, Division of Neonatology, Stanford University School of Medicine and Lucile Packard Children s Hospital, Palo Alto, CA 94304, USA
Pediatrics 125:e146-54. 2010..Accurate models for predicting time to hospital discharge could aid in resource planning, family counseling, and stimulate quality-improvement initiatives...
Impact of timing of birth and resident duty-hour restrictions on outcomes for small preterm infantsEdward F Bell
Department of Pediatrics, University of Iowa, Iowa City, IA 52242, USA
Pediatrics 126:222-31. 2010....
Late-onset sepsis in very low birth weight neonates: the experience of the NICHD Neonatal Research NetworkBarbara J Stoll
Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia 30322, USA
Pediatrics 110:285-91. 2002..Strategies to reduce late-onset sepsis and its medical, social, and economic toll need to be addressed urgently...
Predictive value of an early amplitude integrated electroencephalogram and neurologic examinationSeetha Shankaran
Department of Pediatrics, Wayne State University, Detroit, Michigan, USA
Pediatrics 128:e112-20. 2011..To examine the predictive validity of the amplitude integrated electroencephalogram (aEEG) and stage of encephalopathy among infants with hypoxic-ischemic encephalopathy (HIE) eligible for therapeutic whole-body hypothermia...
Parenteral glutamine supplementation does not reduce the risk of mortality or late-onset sepsis in extremely low birth weight infantsBrenda B Poindexter
Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA
Pediatrics 113:1209-15. 2004..Whether glutamine supplementation would provide a similar benefit to extremely low birth weight (ELBW) infants is not known...
Maternal age, multiple birth, and extremely low birth weight infantsBetty R Vohr
Department of Pediatrics, The Warren Alpert Medical School of Brown University, Providence, RI, USA
J Pediatr 154:498-503.e2. 2009..To compare the rates of adverse neurodevelopmental outcome or death at 18 to 22 months among extremely low birth weight (ELBW) infants born to mothers >or=4 0 years to the corresponding rates among infants of younger mothers...
Very low birth weight preterm infants with surgical short bowel syndrome: incidence, morbidity and mortality, and growth outcomes at 18 to 22 monthsConrad R Cole
Emory University School of Medicine, Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, 2015 Uppergate Dr, Atlanta, GA 30322, USA
Pediatrics 122:e573-82. 2008....
Inhaled nitric oxide for premature infants with severe respiratory failureKrisa P Van Meurs
Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, Calif 94304, USA
N Engl J Med 353:13-22. 2005..We conducted a multicenter, randomized, blinded, controlled trial to determine whether inhaled nitric oxide reduced the rate of death or bronchopulmonary dysplasia in such infants...
Neonatal candidiasis: epidemiology, risk factors, and clinical judgmentDaniel K Benjamin
Department of Pediatrics, Duke University, Duke Clinical Research Institute, 2400 Pratt St, Durham, NC 27705, USA
Pediatrics 126:e865-73. 2010..We quantified risk factors that predict infection in premature infants at high risk and compared clinical judgment with a prediction model of invasive candidiasis...
To tap or not to tap: high likelihood of meningitis without sepsis among very low birth weight infantsBarbara J Stoll
Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA
Pediatrics 113:1181-6. 2004..Because CSF cultures were performed only half as often as BCs, this discordance in blood and CSF culture results suggests that meningitis may be underdiagnosed among VLBW infants...
Early nutrition mediates the influence of severity of illness on extremely LBW infantsRichard A Ehrenkranz
Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520, USA
Pediatr Res 69:522-9. 2011....
Antenatal consent in the SUPPORT trial: challenges, costs, and representative enrollmentWade D Rich
Department of Pediatrics, School of Medicine, University of California, San Diego, California, USA
Pediatrics 126:e215-21. 2010....
Early-childhood neurodevelopmental outcomes are not improving for infants born at <25 weeks' gestational ageSusan R Hintz
Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, 750 Welch Rd, Suite 315, Palo Alto, CA 94304, USA
Pediatrics 127:62-70. 2011..We compared neurodevelopmental outcomes at 18 to 22 months' corrected age of infants born with extremely low birth weight at an estimated gestational age of <25 weeks during 2 periods: 1999-2001 (epoch 1) and 2002-2004 (epoch 2)...
Synchronized nasal intermittent positive-pressure ventilation and neonatal outcomesVineet Bhandari
Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520 8064, USA
Pediatrics 124:517-26. 2009..Limited information is available on the outcomes of infants managed with SNIPPV...
Neonatal candidiasis among extremely low birth weight infants: risk factors, mortality rates, and neurodevelopmental outcomes at 18 to 22 monthsDaniel K Benjamin
Department of Pediatrics, Duke Clinical Research Institute, Duke University, Durham, North Carolina, USA
Pediatrics 117:84-92. 2006..Neonatal candidiasis is associated with substantial morbidity and mortality rates. Neurodevelopmental follow-up data for a large multicenter cohort have not been reported...
Survival and morbidity outcomes for very low birth weight infants with Down syndromeNansi S Boghossian
University of Iowa Health Care, Department of Pediatrics, 200 Hawkins Dr, Iowa City, IA 52242, USA
Pediatrics 126:1132-40. 2010....
Neonatal outcomes of extremely preterm infants from the NICHD Neonatal Research NetworkBarbara J Stoll
Department of Pediatrics, Emory University School of Medicine and Children s Healthcare of Atlanta, 2015 Uppergate Dr, Atlanta, GA 30322, USA
Pediatrics 126:443-56. 2010....
Predictors of death or bronchopulmonary dysplasia in preterm infants with respiratory failureN Ambalavanan
Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35249, USA
J Perinatol 28:420-6. 2008..To identify the variables that predict death/physiologic bronchopulmonary dysplasia (BPD) in preterm infants with severe respiratory failure...
Does labor influence neonatal and neurodevelopmental outcomes of extremely-low-birth-weight infants who are born by cesarean delivery?Rajan Wadhawan
National Institute for Child Health and Human Development Neonatal Research Network, Bethesda, MD 02905, USA
Am J Obstet Gynecol 189:501-6. 2003..We hypothesized that infants who are born by cesarean delivery without labor will have better outcomes than those infants who are born by cesarean delivery with labor...
Delayed cord clamping in very preterm infants reduces the incidence of intraventricular hemorrhage and late-onset sepsis: a randomized, controlled trialJudith S Mercer
University of Rhode Island, Kingston, RI, USA
Pediatrics 117:1235-42. 2006..Other outcome variables were late-onset sepsis (LOS) and intraventricular hemorrhage (IVH)...
Very low birth weight preterm infants with early onset neonatal sepsis: the predominance of gram-negative infections continues in the National Institute of Child Health and Human Development Neonatal Research Network, 2002-2003Barbara J Stoll
Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA
Pediatr Infect Dis J 24:635-9. 2005..CONCLUSION: EOS remains an uncommon but important cause of morbidity and mortality among VLBW infants. Gram-negative organisms continue to be the predominant pathogens associated with EOS...
Prolonged hospital stay for extremely premature infants: risk factors, center differences, and the impact of mortality on selecting a best-performing centerC Michael Cotten
Department of Pediatrics, Duke University School of Medicine, Durham, NC 27710, USA
J Perinatol 25:650-5. 2005..CONCLUSIONS: These findings suggest that reduction of CLD, surgical NEC, and late onset sepsis could reduce PHS in EP infants. Risk adjusted odds of PHS and mortality are both crucial for selecting a PHS best-performing center...
Stability of neuromotor outcomes at 18 and 30 months of age after extremely low birth weight statusMyriam Peralta-Carcelen
Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama, USA
Pediatrics 123:e887-95. 2009..Extremely low birth weight (< or =1000 g) children have increased rates of cerebral palsy and other abnormal neurologic findings...
Prolonged duration of initial empirical antibiotic treatment is associated with increased rates of necrotizing enterocolitis and death for extremely low birth weight infantsC Michael Cotten
Department of Pediatrics, Duke University, Durham, NC 27710, USA
Pediatrics 123:58-66. 2009....
Hypocarbia and adverse outcome in neonatal hypoxic-ischemic encephalopathyAthina Pappas
Department of Pediatrics, Wayne State University School of Medicine, Detroit, MI 48201, USA
J Pediatr 158:752-758.e1. 2011..To evaluate the association between early hypocarbia and 18- to 22-month outcome among neonates with hypoxic-ischemic encephalopathy...
Prediction of bronchopulmonary dysplasia by postnatal age in extremely premature infantsMatthew M Laughon
Department of Pediatrics, University of North Carolina, Chapel Hill, North Carolina 27599 7596, USA
Am J Respir Crit Care Med 183:1715-22. 2011....
Elevated temperature after hypoxic-ischemic encephalopathy: risk factor for adverse outcomesAbbot Laptook
Department of Pediatrics, Women and Infants Hospital of Rhode Island, 101 Dudley St, Providence, RI 02906, USA
Pediatrics 122:491-9. 2008....
Intercenter differences in bronchopulmonary dysplasia or death among very low birth weight infantsNamasivayam Ambalavanan
Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35249, USA
Pediatrics 127:e106-16. 2011....
Perinatal systemic inflammatory response syndrome and retinopathy of prematurityBeena G Sood
Department of Pediatrics, Wayne State University, Detroit, Michigan 48201, USA
Pediatr Res 67:394-400. 2010..We conclude that perinatal inflammation may be involved in the pathogenesis of ROP...
Is phototherapy exposure associated with better or worse outcomes in 501- to 1000-g-birth-weight infants?Susan R Hintz
Department of Pediatrics, Stanford University School of Medicine, Palo Alto, CA, USA
Acta Paediatr 100:960-5. 2011..Conservative Phototherapy...
T cell cytokines and the risk of blood stream infection in extremely low birth weight infantsRobert L Schelonka
Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA
Cytokine 53:249-55. 2011..Altered maturation of regulatory and inflammatory cytokines may increase the risk of serious infection in this population...
Community supports after surviving extremely low-birth-weight, extremely preterm birth: special outpatient services in early childhoodSusan R Hintz
Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, California 94304, USA
Arch Pediatr Adolesc Med 162:748-55. 2008..To determine special outpatient services (SOS) use, need, associated factors, and neurodevelopmental and functional outcomes among extremely preterm infants at 18 to 22 months' corrected age...
Cytokines associated with bronchopulmonary dysplasia or death in extremely low birth weight infantsNamasivayam Ambalavanan
Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35249, USA
Pediatrics 123:1132-41. 2009..The goal was to develop multivariate logistic regression models for the outcome of bronchopulmonary dysplasia and/or death at postmenstrual age of 36 weeks by using clinical and cytokine data from the first 28 days...
Changes in pathogens causing early-onset sepsis in very-low-birth-weight infantsBarbara J Stoll
Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA
N Engl J Med 347:240-7. 2002..The change in pathogens over time from predominantly gram-positive to predominantly gram-negative requires confirmation by ongoing surveillance...
Prevention of intraventricular hemorrhage by indomethacin in male preterm infantsLaura R Ment
Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA
J Pediatr 145:832-4. 2004..Analysis of our cohort by sex showed indomethacin halved the incidence of IVH, eliminated parenchymal hemorrhage, and was associated with higher verbal scores at 3 to 8 years in boys...
Hemodynamic effects of delayed cord clamping in premature infantsRoss Sommers
Department of Neonatology, Women and Infants Hospital of Rhode Island and Alpert Medical School of Brown University, Providence, RI 02905, USA
Pediatrics 129:e667-72. 2012..Our objective was to compare the hemodynamic differences between premature infants randomized to either DCC or immediate cord clamping (ICC)...
Human milk intake and retinopathy of prematurity in extremely low birth weight infantsCherrie D Heller
Department of Pediatrics, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
Pediatrics 120:1-9. 2007..Our goal was to analyze the association between human milk intake and severe retinopathy of prematurity in extremely low birth weight infants...
Association between urinary lactate to creatinine ratio and neurodevelopmental outcome in term infants with hypoxic-ischemic encephalopathyWilliam Oh
Department of Pediatrics, Warren Alpert Medical School of Brown University, Providence, RI, USA
J Pediatr 153:375-8. 2008..To assess the association between urinary lactate to creatinine ratio (ULCR) and neurodevelopmental outcome in term infants with hypoxic ischemic encephalopathy and examine the effect of hypothermia on the change in ULCR...
Ontogeny of bilirubin-binding capacity and the effect of clinical status in premature infants born at less than 1300 gramsGeorge Jesse Bender
Department of Pediatrics, Brown Medical School, Women and Infants Hospital of Rhode Island, 100 Dudley St, Providence, RI 02860, USA
Pediatrics 120:1067-73. 2007..Unbound bilirubin levels may depend on the bilirubin-binding capacity of albumin, which has not been described for neonates of <28 weeks' gestation...
Congenital hypothyroidism with a delayed thyroid-stimulating hormone elevation in very premature infants: incidence and growth and developmental outcomesHyung Chul Woo
Department of Pediatrics, The Warren Alpert Medical School of Brown University, Providence, RI, USA
J Pediatr 158:538-42. 2011....
Oral probiotics reduce the incidence and severity of necrotizing enterocolitis in very low birth weight infantsHung Chih Lin
Department of Pediatrics, China Medical University Hospital, China Medical University, 2 Yuh Der Rd, Taichung 404, Taiwan
Pediatrics 115:1-4. 2005..We evaluated the efficacy of probiotics in reducing the incidence and severity of necrotizing enterocolitis (NEC) in very low birth weight (VLBW) infants...
Trends in neonatal morbidity and mortality for very low birthweight infantsAvroy A Fanaroff
Department of Pediatrics, Case Western Reserve University, Cleveland, OH
Am J Obstet Gynecol 196:147.e1-8. 2007..To document the mortality and morbidity of infants weighing 501-1500 g at birth according to gestational age, birthweight, and sex...
Effects of sample dilution, peroxidase concentration, and chloride ion on the measurement of unbound bilirubin in premature newbornsCharles E Ahlfors
PO Box 2904, Vashon, WA 98070, USA
Clin Biochem 40:261-7. 2007....
Minimal ventilation to prevent bronchopulmonary dysplasia in extremely-low-birth-weight infantsWaldemar A Carlo
University of Alabama at Birmingham, Division of Neonatology, 35233, USA
J Pediatr 141:370-4. 2002..CONCLUSIONS: With the sample size studied, minimal ventilation did not reduce the incidence of death or BPD. The reduced ventilator support at 36 weeks in the minimal ventilation group warrants further study of this intervention...
Risk factors for early death among extremely low-birth-weight infantsSeetha Shankaran
Wayne State University, Detroit, Michigan, USA
Am J Obstet Gynecol 186:796-802. 2002..4; 95% CI, 1.3-1.6), and lower birth weight per 50 g (95% CI, 1.2-1.4). CONCLUSION: Early death (<12 hours of age) among extremely low-birth-weight infants may reflect an assessment of non-viability by obstetricians and neonatologists...
Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathySeetha Shankaran
Division of Neonatal Perinatal Medicine, Wayne State University, Children s Hospital of Michigan, Detroit, MI 48201, USA
N Engl J Med 353:1574-84. 2005..Hypothermia is protective against brain injury after asphyxiation in animal models. However, the safety and effectiveness of hypothermia in term infants with encephalopathy is uncertain...
Aggressive vs. conservative phototherapy for infants with extremely low birth weightBrenda H Morris
University of Texas Medical School, Houston, TX 77030, USA
N Engl J Med 359:1885-96. 2008..It is unclear whether aggressive phototherapy to prevent neurotoxic effects of bilirubin benefits or harms infants with extremely low birth weight (1000 g or less)...
Neurodevelopmental outcome of premature infants after antenatal phenobarbital exposureSeetha Shankaran
Wayne State University, Detroit, MI, USA
Am J Obstet Gynecol 187:171-7. 2002....
Neurodevelopmental outcome of extremely low birth weight infants with posthemorrhagic hydrocephalus requiring shunt insertionIra Adams-Chapman
Department of Pediatrics Division of Neonatology, Emory University School of Medicine, 46 Jesse Hill Jr Drive SE, Atlanta, GA 30303, USA
Pediatrics 121:e1167-77. 2008..We aimed to evaluate neurodevelopmental and growth outcomes among extremely low birth weight infants who had severe intraventricular hemorrhage that required shunt insertion compared with infants without shunt insertion...
Initial decline in hemoglobin during neoadjuvant hormonal therapy predicts for early prostate specific antigen failure following radiation and hormonal therapy for patients with intermediate and high-risk prostate cancerAnthony V D'Amico
Department of Radiation Oncology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
Cancer 95:275-80. 2002....
Effect of parenteral glutamine supplementation on plasma amino acid concentrations in extremely low-birth-weight infantsBrenda B Poindexter
Indiana University, Indianapolis, USA
Am J Clin Nutr 77:737-43. 2003..Currently available amino acid solutions are likely to be suboptimal in their supply of phenylalanine, tyrosine, or both for these infants...
Indomethacin prophylaxis for preterm infants: the impact of 2 multicentered randomized controlled trials on clinical practiceRonald I Clyman
Cardiovascular Research Institute and Department of Pediatrics, University of California San Francisco, San Francisco, CA 94143 0544, USA
J Pediatr 150:46-50.e2. 2007..The TIPP trial failed to find a benefit in its primary outcome (improved survival/neurodevelopmental outcome); this negative result may have discouraged indomethacin prophylaxis use...
Whole-body hypothermia for neonatal encephalopathy: animal observations as a basis for a randomized, controlled pilot study in term infantsSeetha Shankaran
Wayne State University, Detroit, Michigan, USA
Pediatrics 110:377-85. 2002....
Oral probiotics prevent necrotizing enterocolitisHung-Chih Lin
J Pediatr 148:849; author reply 850. 2006
Immediate and delayed cord clamping in infants born between 24 and 32 weeks: a pilot randomized controlled trialJudith S Mercer
College of Nursing, University of Rhode Island, White Hall, 2 Heathman Road, Kingston, RI 02881-2021, USA
J Perinatol 23:466-72. 2003..1 mg/dl; p=0.02). CONCLUSION: The research design is feasible. The immediate benefit of improved blood pressure was confirmed and other findings deserve consideration for further study...
