Affiliation: Women and Infants Hospital
- Integrated serum screening for Down syndrome in primary obstetric practiceGeorge J Knight
Foundation for Blood Research, Scarborough, Maine, USA
Prenat Diagn 25:1162-7. 2005..We report results of an intervention trial of integrated serum screening that involved 229 primary prenatal care practitioners throughout Maine...
- Maternal serum-integrated screening for trisomy 18 using both first- and second-trimester markersGlenn E Palomaki
Foundation for Blood Research, PO Box 190, Scarborough, Maine 04070 0190, USA
Prenat Diagn 23:243-7. 2003..To estimate the prenatal screening performance of an integrated serum test for detecting trisomy 18, which combines measurements of first- and second-trimester markers with maternal age to assign patient-specific risks...
- Repeated measurement of pregnancy-associated plasma protein-A (PAPP-A) in Down syndrome screening: a validation studyGlenn E Palomaki
Women and Infants Hospital, Providence, Rhode Island 02903, USA
Prenat Diagn 26:730-9. 2006..To confirm that measuring pregnancy-associated plasma protein-A (PAPP-A) in both first- and second-trimester serum samples improves Down syndrome screening...
- Comparing three screening strategies for combining first- and second-trimester Down syndrome markersGlenn E Palomaki
Division of Medical Screening, Department of Pathology and Laboratory Medicine, Women and Infants Hospital, Providence, RI 02903, USA
Obstet Gynecol 107:367-75. 2006..To describe the choices and tradeoffs inherent in 3 published strategies that combine first- and second-trimester markers for Down syndrome screening...
- Patient and health professional acceptance of integrated serum screening for Down syndromeGlenn E Palomaki
Department of Biometry, Foundation for Blood Research, Scarborough, ME, USA
Semin Perinatol 29:247-51. 2005..Women receiving prenatal care at the primary care level are prepared to wait until the second trimester for more accurate Down syndrome risk estimates on which to base their decision-making...
- Maternal serum invasive trophoblast antigen and first-trimester Down syndrome screeningGlenn E Palomaki
Foundation for Blood Research, Scarborough, ME, USA
Clin Chem 51:1499-504. 2005..The current report describes a case-control study of serum invasive trophoblast antigen (ITA) and its possible inclusion in first-trimester screening for Down syndrome...
- Maternal serum invasive trophoblast antigen (hyperglycosylated hCG) as a screening marker for Down syndrome during the second trimesterGlenn E Palomaki
Foundation for Blood Research, Scarborough, ME 04070 00190, USA
Clin Chem 50:1804-8. 2004..This study aims at better defining the screening performance of serum ITA in the second trimester...
- Invasive trophoblast antigen (hyperglycosylated human chorionic gonadotropin) in second-trimester maternal urine as a marker for down syndrome: preliminary results of an observational study on fresh samplesGlenn E Palomaki
Foundation for Blood Research, PO Box 190, Scarborough, ME 04070 0190, USA
Clin Chem 50:182-9. 2004..We report preliminary results for urinary ITA in an ongoing observational study...
- Estimating first-trimester combined screening performance for Down syndrome in dried blood spots versus fresh seraGlenn E Palomaki
Women and Infants Hospital Brown University, Providence, Rhode Island 02903, USA
Genet Med 9:458-63. 2007..The study purpose was to examine the consequences of using dried blood spots rather than fresh sera in first-trimester Down syndrome screening...
- A comparison of human chorionic gonadotropin- related components in fresh frozen serum with the proficiency testing material used by the College of American PathologistsGeorge J Knight
Foundation for Blood Research, Scarborough, ME 04074, USA
Arch Pathol Lab Med 129:328-30. 2005..The goal is to gain insight into the possible source(s) of bias attributable to the proficiency testing material (PTM) with a view toward creating more appropriate survey materials...
- Epidemiologic monitoring of prenatal screening for neural tube defects and Down syndromeGeorge J Knight
Prenatal Screening Laboratory, Foundation for Blood Research, Post Office Box 190, Scarborough, ME 04070, USA
Clin Lab Med 23:531-51, xi. 2003..Epidemiologic monitoring also provides useful information for physicians, public health authorities, and regulatory bodies...
- Are IQs low in offspring of euthyroid women with low T4George Knight; Fiscal Year: 2004..It is intended that the study be continued for five more years (total of 10) in order to obtain additional estimates of neuropsychological development in the children at a time when more extensive testing can be performed. ..