George Knight

Summary

Affiliation: Women and Infants Hospital
Country: USA

Publications

  1. ncbi request reprint Integrated serum screening for Down syndrome in primary obstetric practice
    George J Knight
    Foundation for Blood Research, Scarborough, Maine, USA
    Prenat Diagn 25:1162-7. 2005
  2. ncbi request reprint Maternal serum-integrated screening for trisomy 18 using both first- and second-trimester markers
    Glenn E Palomaki
    Foundation for Blood Research, PO Box 190, Scarborough, Maine 04070 0190, USA
    Prenat Diagn 23:243-7. 2003
  3. ncbi request reprint Repeated measurement of pregnancy-associated plasma protein-A (PAPP-A) in Down syndrome screening: a validation study
    Glenn E Palomaki
    Women and Infants Hospital, Providence, Rhode Island 02903, USA
    Prenat Diagn 26:730-9. 2006
  4. ncbi request reprint Comparing three screening strategies for combining first- and second-trimester Down syndrome markers
    Glenn E Palomaki
    Division of Medical Screening, Department of Pathology and Laboratory Medicine, Women and Infants Hospital, Providence, RI 02903, USA
    Obstet Gynecol 107:367-75. 2006
  5. ncbi request reprint Patient and health professional acceptance of integrated serum screening for Down syndrome
    Glenn E Palomaki
    Department of Biometry, Foundation for Blood Research, Scarborough, ME, USA
    Semin Perinatol 29:247-51. 2005
  6. ncbi request reprint Maternal serum invasive trophoblast antigen and first-trimester Down syndrome screening
    Glenn E Palomaki
    Foundation for Blood Research, Scarborough, ME, USA
    Clin Chem 51:1499-504. 2005
  7. ncbi request reprint Maternal serum invasive trophoblast antigen (hyperglycosylated hCG) as a screening marker for Down syndrome during the second trimester
    Glenn E Palomaki
    Foundation for Blood Research, Scarborough, ME 04070 00190, USA
    Clin Chem 50:1804-8. 2004
  8. ncbi request reprint Invasive trophoblast antigen (hyperglycosylated human chorionic gonadotropin) in second-trimester maternal urine as a marker for down syndrome: preliminary results of an observational study on fresh samples
    Glenn E Palomaki
    Foundation for Blood Research, PO Box 190, Scarborough, ME 04070 0190, USA
    Clin Chem 50:182-9. 2004
  9. ncbi request reprint Estimating first-trimester combined screening performance for Down syndrome in dried blood spots versus fresh sera
    Glenn E Palomaki
    Women and Infants Hospital Brown University, Providence, Rhode Island 02903, USA
    Genet Med 9:458-63. 2007
  10. ncbi request reprint A comparison of human chorionic gonadotropin- related components in fresh frozen serum with the proficiency testing material used by the College of American Pathologists
    George J Knight
    Foundation for Blood Research, Scarborough, ME 04074, USA
    Arch Pathol Lab Med 129:328-30. 2005

Research Grants

Detail Information

Publications11

  1. ncbi request reprint Integrated serum screening for Down syndrome in primary obstetric practice
    George J Knight
    Foundation for Blood Research, Scarborough, Maine, USA
    Prenat Diagn 25:1162-7. 2005
    ..We report results of an intervention trial of integrated serum screening that involved 229 primary prenatal care practitioners throughout Maine...
  2. ncbi request reprint Maternal serum-integrated screening for trisomy 18 using both first- and second-trimester markers
    Glenn E Palomaki
    Foundation for Blood Research, PO Box 190, Scarborough, Maine 04070 0190, USA
    Prenat Diagn 23:243-7. 2003
    ..To estimate the prenatal screening performance of an integrated serum test for detecting trisomy 18, which combines measurements of first- and second-trimester markers with maternal age to assign patient-specific risks...
  3. ncbi request reprint Repeated measurement of pregnancy-associated plasma protein-A (PAPP-A) in Down syndrome screening: a validation study
    Glenn E Palomaki
    Women and Infants Hospital, Providence, Rhode Island 02903, USA
    Prenat Diagn 26:730-9. 2006
    ..To confirm that measuring pregnancy-associated plasma protein-A (PAPP-A) in both first- and second-trimester serum samples improves Down syndrome screening...
  4. ncbi request reprint Comparing three screening strategies for combining first- and second-trimester Down syndrome markers
    Glenn E Palomaki
    Division of Medical Screening, Department of Pathology and Laboratory Medicine, Women and Infants Hospital, Providence, RI 02903, USA
    Obstet Gynecol 107:367-75. 2006
    ..To describe the choices and tradeoffs inherent in 3 published strategies that combine first- and second-trimester markers for Down syndrome screening...
  5. ncbi request reprint Patient and health professional acceptance of integrated serum screening for Down syndrome
    Glenn E Palomaki
    Department of Biometry, Foundation for Blood Research, Scarborough, ME, USA
    Semin Perinatol 29:247-51. 2005
    ..Women receiving prenatal care at the primary care level are prepared to wait until the second trimester for more accurate Down syndrome risk estimates on which to base their decision-making...
  6. ncbi request reprint Maternal serum invasive trophoblast antigen and first-trimester Down syndrome screening
    Glenn E Palomaki
    Foundation for Blood Research, Scarborough, ME, USA
    Clin Chem 51:1499-504. 2005
    ..The current report describes a case-control study of serum invasive trophoblast antigen (ITA) and its possible inclusion in first-trimester screening for Down syndrome...
  7. ncbi request reprint Maternal serum invasive trophoblast antigen (hyperglycosylated hCG) as a screening marker for Down syndrome during the second trimester
    Glenn E Palomaki
    Foundation for Blood Research, Scarborough, ME 04070 00190, USA
    Clin Chem 50:1804-8. 2004
    ..This study aims at better defining the screening performance of serum ITA in the second trimester...
  8. ncbi request reprint Invasive trophoblast antigen (hyperglycosylated human chorionic gonadotropin) in second-trimester maternal urine as a marker for down syndrome: preliminary results of an observational study on fresh samples
    Glenn E Palomaki
    Foundation for Blood Research, PO Box 190, Scarborough, ME 04070 0190, USA
    Clin Chem 50:182-9. 2004
    ..We report preliminary results for urinary ITA in an ongoing observational study...
  9. ncbi request reprint Estimating first-trimester combined screening performance for Down syndrome in dried blood spots versus fresh sera
    Glenn E Palomaki
    Women and Infants Hospital Brown University, Providence, Rhode Island 02903, USA
    Genet Med 9:458-63. 2007
    ..The study purpose was to examine the consequences of using dried blood spots rather than fresh sera in first-trimester Down syndrome screening...
  10. ncbi request reprint A comparison of human chorionic gonadotropin- related components in fresh frozen serum with the proficiency testing material used by the College of American Pathologists
    George J Knight
    Foundation for Blood Research, Scarborough, ME 04074, USA
    Arch Pathol Lab Med 129:328-30. 2005
    ..The goal is to gain insight into the possible source(s) of bias attributable to the proficiency testing material (PTM) with a view toward creating more appropriate survey materials...
  11. ncbi request reprint Epidemiologic monitoring of prenatal screening for neural tube defects and Down syndrome
    George J Knight
    Prenatal Screening Laboratory, Foundation for Blood Research, Post Office Box 190, Scarborough, ME 04070, USA
    Clin Lab Med 23:531-51, xi. 2003
    ..Epidemiologic monitoring also provides useful information for physicians, public health authorities, and regulatory bodies...

Research Grants1

  1. Are IQs low in offspring of euthyroid women with low T4
    George Knight; Fiscal Year: 2004
    ..It is intended that the study be continued for five more years (total of 10) in order to obtain additional estimates of neuropsychological development in the children at a time when more extensive testing can be performed. ..