Research Topics
Genomes and Genes | Meredith DixonSummaryAffiliation: Women and Infants' Hospital Country: USA Publications
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Detail Information
Publications
Postmortem RNA and protein stability in perinatal human lungsMonique E De Paepe
Department of Pathology, Women and Infants Hospital, Providence, RI 02905, USA
Diagn Mol Pathol 11:170-6. 2002..RNA is equivalent, if not superior, to LN for preservation of postmortem RNA and protein in developing human lungs...
Ex vivo expanded human cord blood-derived hematopoietic progenitor cells induce lung growth and alveolarization in injured newborn lungsQuanfu Mao
Department of Pathology, Women and Infants Hospital, Providence, RI, USA
Respir Res 14:37. 2013....
Long-term outcome of human cord blood-derived hematopoietic progenitor cells in murine lungsMonique E De Paepe
Department of Pathology, Women and Infants Hospital, Providence, Rhode Island 02905, USA
Exp Lung Res 39:59-69. 2013..Cord blood-CD34+ cell administration appears to have growth-promoting effects in injured newborn lungs, without affecting alveolar development in this model...
The human fetal lung xenograft: validation as model of microvascular remodeling in the postglandular lungMonique E De Paepe
Department of Pathology, Women and Infants Hospital, Brown University, Providence, RI, USA
Pediatr Pulmonol 47:1192-203. 2012..Coordinated remodeling of epithelium and vasculature is essential for normal postglandular lung development. The value of the human-to-rodent lung xenograft as model of fetal microvascular development remains poorly defined...
Correlation between cord insertion type and superficial choriovasculature in diamniotic-monochorionic twin placentasM E De Paepe
Department of Pathology, Women and Infants Hospital, Alpert Medical School of Brown University, Providence, RI 02905, USA
Placenta 32:901-5. 2011..The choriovascular correlates of peripheral cord insertion in diamniotic-monochorionic twin placentas remain undetermined...
Resilience of the human fetal lung following stillbirth: potential relevance for pulmonary regenerative medicineMonique E De Paepe
Department of Pathology, Women and Infants Hospital, and Department of Pathology and Laboratory Medicine, Alpert Medical School of Brown University, Providence, Rhode Island 02905, USA
Exp Lung Res 38:43-54. 2012..In conclusion, fetal lung tissues from second trimester stillbirths can regain their inherent high regenerative potential following short-term culture, even if harvested more than 36 hours after delivery...
Placental markers of twin-to-twin transfusion syndrome in diamniotic-monochorionic twins: A morphometric analysis of deep artery-to-vein anastomosesM E De Paepe
Department of Pathology, Women and Infants Hospital, Providence, RI 02905, USA
Placenta 31:269-76. 2010..Elucidation of the role of the various placental determinants in diamniotic-monochorionic twin gestations may lead to further refinement of therapeutic strategies...
Placental characteristics of selective birth weight discordance in diamniotic-monochorionic twin gestationsM E De Paepe
Department of Pathology, Women and Infants Hospital, 101 Dudley Street, Providence, RI 02905, USA
Placenta 31:380-6. 2010..Elucidation of the mechanisms whereby velamentous cord insertion affects fetal growth may lead to more focused and effective therapeutic strategies for twin and singleton pregnancies complicated by dysregulated fetal growth...
Effects of Fas-ligand overexpression on alveolar type II cell growth kinetics in perinatal murine lungsMonique E De Paepe
Department of Pathology, Women and Infants Hospital, and Department of Pathology and Laboratory Medicine, Alpert Medical School of Brown University, Providence, Rhode Island 02905, USA
Pediatr Res 68:57-62. 2010..In conclusion, these results, and our previous studies, suggest that FasL signaling has dual timing-dependent proapoptotic and proproliferative effects on postcanalicular type II cell kinetics...
Angiogenesis-related gene expression profiling in ventilated preterm human lungsMonique E De Paepe
Department of Pathology, Women and Infants Hospital, Providence, Rhode Island 02905, USA
Exp Lung Res 36:399-410. 2010..This angiogenic shift may be implicated in the regulation of dysmorphic angiogenesis and, consequently, deficient alveolarization characteristic of infants with BPD...
Intrauterine demise due to congenital mesoblastic nephroma in a fetus conceived by assisted reproductive technologyMonique E De Paepe
Department of Pathology, Women and Infants Hospital, Providence, Rhode Island 02905, USA
Fertil Steril 95:1119.e15-7. 2011..To report a case of antenatally diagnosed congenital mesoblastic nephroma in an assisted reproductive technology (ART) conception...
Alveolar epithelial cell therapy with human cord blood-derived hematopoietic progenitor cellsMonique E De Paepe
Department of Pathology, Women and Infants Hospital, Providence, Rhode Island 02905, USA
Am J Pathol 178:1329-39. 2011..Graft proliferation and alveolar epithelial differentiation are promoted by lung injury...
Pulmonary dendritic cells in lungs of preterm infants: neglected participants in bronchopulmonary dysplasia?Monique E De Paepe
Department of Pathology, Women and Infants Hospital, Providence, RI, USA
Pediatr Dev Pathol 14:20-7. 2011..Elucidation of the role of this immunovascular axis may lead to novel therapeutic approaches to BPD...
Fas-ligand-induced apoptosis of respiratory epithelial cells causes disruption of postcanalicular alveolar developmentMonique E De Paepe
Women and Infants Hospital, Dept of Pathology, 101 Dudley St, Providence, RI 02905, USA
Am J Pathol 173:42-56. 2008....
Renal tubular apoptosis in twin-to-twin transfusion syndromeMonique E De Paepe
Department of Pathology, Women and Infants Hospital, 101 Dudley Street, Providence, RI 02905, USA
Pediatr Dev Pathol 6:215-25. 2003..We speculate that the risk for development of tubular apoptosis in TTTS depends on the severity and timing of the hemodynamic imbalance, whereby early mid-trimester fetuses may be more vulnerable...
Postmortem validation of imaging-derived formulas for prediction of fetal lung volumeMonique E De Paepe
Department of Pathology, Women and Infants Hospital, Providence, RI 02905, USA
Fetal Diagn Ther 18:353-9. 2003..To determine the validity of existing imaging-derived formulas for predicting the fetal lung volume (FLV)...
Placental findings after laser ablation of communicating vessels in twin-to-twin transfusion syndromeMonique E De Paepe
Department of Pathology, Women and Infants Hospital, Providence, RI 02905, USA
Pediatr Dev Pathol 7:159-65. 2004..Detailed analysis of laser-treated placentas and clinicopathological correlation may lead to a better understanding of the pathophysiology of TTTS and continued refinement of therapeutic approaches for this often lethal condition...
Fas/FasL-mediated apoptosis in perinatal murine lungsMonique E De Paepe
Program of Fetal Medicine, Women and Infants Hospital, Providence, RI 02905, USA
Am J Physiol Lung Cell Mol Physiol 287:L730-42. 2004..The developmental time dependence of apoptosis-related events in the murine model should facilitate investigations of the regulation of perinatal pulmonary apoptotic gene expression...
Vascular distribution patterns in monochorionic twin placentasM E De Paepe
Department of Pathology, Women and Infants Hospital and Brown Medical School, 101 Dudley Street, Providence, RI 02905, United States
Placenta 26:471-5. 2005..These findings suggest that the magistral/mixed vascular distribution pattern may represent an important placental architectural feature contributing to the complex pathophysiology of TTTS...
Hyperoxia-induced apoptosis and Fas/FasL expression in lung epithelial cellsMonique E De Paepe
Dept of Pathology, Women and Infants Hospital, Brown Medical School, Providence, RI 02905, USA
Am J Physiol Lung Cell Mol Physiol 289:L647-59. 2005..Elucidation of regulation of hyperoxia-induced lung apoptosis may lead to alternative therapeutic strategies for perinatal or adult pulmonary diseases characterized by dysregulated type II cell apoptosis...
Postmortem lung weight/body weight standards for term and preterm infantsMonique E De Paepe
Department of Pathology, Women and Infants Hospital and Brown University Medical School, Providence, Rhode Island 02905, USA
Pediatr Pulmonol 40:445-8. 2005..Correlation of LW/BW with age-matched reference values at postmortem examination represents an invaluable additional tool to evaluate lung growth, particularly in preterm infants...
Growth of pulmonary microvasculature in ventilated preterm infantsMonique E De Paepe
Women and Infants Hospital, Department of Pathology, 101 Dudley Street, Providence, RI 02905, USA
Am J Respir Crit Care Med 173:204-11. 2006....
Endoglin (CD105) up-regulation in pulmonary microvasculature of ventilated preterm infantsMonique E De Paepe
Women and Infants Hospital, Department of Pathology, 101 Dudley Street, Providence, RI 02905, USA
Am J Respir Crit Care Med 178:180-7. 2008..The molecular regulation of this BPD-associated dysangiogenesis remains undetermined...
Educational and occupational outcomes among survivors of childhood cancer during the transition to emerging adulthoodCynthia A Gerhardt
Center for Biobehavioral Health, The Ohio State University, Columbus, Ohio, USA
J Dev Behav Pediatr 28:448-55. 2007..To examine educational and occupational outcomes among survivors of childhood cancer and peers during the transition from adolescence to emerging adulthood...
